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AIDS Malignancies Training and Research International Program (AMTRIP)

Award Number: D43TW010354
ORGANIZATION: FOGARTY INTERNATIONAL CENTER
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 02/01/2022
PERIOD OF PERFORMANCE END DATE: 03/31/2026

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AIDS Malignancies Training and Research International Program (AMTRIP) - PROJECT SUMMARY/ABSTRACT HIV/AIDS is at epidemic proportions in Zambia, where approximately 1.2 million people – representing about 12% of the country's adult population – are infected. Concomitant with this epidemic, the widespread availability of free anti-retroviral treatment in-country has increased the lifespan of HIV-1 infected individuals, resulting in prolonged chronic immunosuppression and increased occurrence of HIV-associated cancers. However, in-country efforts to prevent, diagnose, and manage cancer in Zambia have been hindered by a lack of laboratory facilities, insufficient cancer research infrastructure, and a shortage of trained personnel. Recognizing these critical gaps, the University of Zambia School of Medicine, the University Teaching Hospitals, and the University of Nebraska-Lincoln leveraged the success of a previous Fogarty partnership to establish the AIDS Malignancies Training and Research International Program (AMTRIP) in collaboration with a new lead partner, the Cancer Diseases Hospital (CDH). This unique program aims to enhance Zambia's cancer research infrastructure and capacity by training Zambian biomedical researchers and health care providers in laboratory techniques and research methodology related to basic cancer biology, molecular genomics, and bioinformatics. Now in its fifth year, AMTRIP has made significant strides by providing intensive long-term graduate degree training and short- and medium-term technical training for a diverse group of 25 trainees; hosting workshops for over 300 health care professionals; successfully transitioning trainees into mentorship roles; adapting program activities to meet the needs of trainees and the rapidly changing cancer research landscape; and leveraging partnerships with other D43 programs to expand the program's impact. Building on these accomplishments, this renewal application seeks to further enhance cancer research capacity in Zambia by: 1) continuing to provide long-term academic instruction and research experiences for eight current master's and three current PhD students in Zambia and recruiting four additional master's and two additional PhD students; 2) providing medium-term (six months to one year) technical training for trainees in topics related to molecular pathology, cancer biology, bioinformatics and genomics; and 3) delivering short- term training (less than three months) and technical workshops (3-5 days) designed to enhance basic, clinical, implementation, genomics, bioinformatics, and behavioral cancer research in collaboration with other regional partners and programs. Expected outcomes of this renewal include the graduation of eight current master's and three current PhD candidates; recruitment and training of an additional four master's and two PhD students in relevant cancer research fields; the transition of trainees into mentorship roles; enhanced infrastructure at Zambian institutions, including the completion of a CDH laboratory renovation; and expanded partnerships with other D43 programs. Given current progress and anticipated renewal outcomes, AMTRIP is on track to transition program leadership to the next generation of cancer researchers in a future renewal.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $150,001 )
2025	2025	LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER NEW ORLEANS	433 BOLIVAR ST RM 619	NEW ORLEANS	LA	70112	ORLEANS	USA	International Research and Research Training	000	11	3/26/2025	NON-COMPETING CONTINUATION	$150,001
														Subtotal = $150,001

Issue Date FY: 2024 ( Subtotal = $291,707 )
2024	2024	LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER NEW ORLEANS	433 BOLIVAR ST RM 619	NEW ORLEANS	LA	70112	ORLEANS	USA	International Research and Research Training	000	10	4/19/2024	NON-COMPETING CONTINUATION	$291,707
														Subtotal = $291,707

Issue Date FY: 2023 ( Subtotal = $291,471 )
2023	2023	LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER-NEW ORLEANS	433 BOLIVAR ST STE 815	NEW ORLEANS	LA	70112	ORLEANS	USA	International Research and Research Training	003	9	3/30/2023	NON-COMPETING CONTINUATION	$0
2023	2023	LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER-NEW ORLEANS	433 BOLIVAR ST STE 815	NEW ORLEANS	LA	70112	ORLEANS	USA	International Research and Research Training	002	9	3/23/2023	NON-COMPETING CONTINUATION	$291,471
2023	2021	BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA	2200 VINE ST	LINCOLN	NE	68503	LANCASTER	USA	International Research and Research Training	000	6	1/18/2023	COMPETING CONTINUATION	-$231,652
2023	2021	LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER-NEW ORLEANS	433 BOLIVAR ST STE 815	NEW ORLEANS	LA	70112	ORLEANS	USA	International Research and Research Training	001	7	1/18/2023	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$231,652
														Subtotal = $291,471

Issue Date FY: 2022 ( Subtotal = $291,708 )
2022	2022	LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER-NEW ORLEANS	433 BOLIVAR ST STE 815	NEW ORLEANS	LA	70112	ORLEANS	USA	International Research and Research Training	003	8	5/6/2022	NON-COMPETING CONTINUATION	$291,707
2022	2021	BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA	2200 VINE ST BOX 830861	LINCOLN	NE	68503	LANCASTER	USA	International Research and Research Training	002	6	5/6/2022	COMPETING CONTINUATION	$1
2022	2021	BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA	2200 VINE ST BOX 830861	LINCOLN	NE	68503	LANCASTER	USA	International Research and Research Training	006	6	6/8/2022	COMPETING CONTINUATION	$231,651
2022	2021	LOUISIANA STATE UNIVERSITY SYSTEM	433 BOLIVAR ST STE 815	NEW ORLEANS	LA	70112	ORLEANS	USA	International Research and Research Training	001	7	1/26/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$287,118
2022	2021	BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA	2200 VINE ST BOX 830861	LINCOLN	NE	68503	LANCASTER	USA	International Research and Research Training	000	6	1/24/2022	COMPETING CONTINUATION	-$287,118
2022	2021	LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER-NEW ORLEANS	433 BOLIVAR ST STE 815	NEW ORLEANS	LA	70112	ORLEANS	USA	International Research and Research Training	004	7	5/6/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2022	2020	BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA	2200 VINE ST BOX 830861	LINCOLN	NE	68503	LANCASTER	USA	International Research and Research Training	005	5	6/8/2022	NON-COMPETING CONTINUATION	-$231,651
														Subtotal = $291,708

Issue Date FY: 2021 ( Subtotal = $287,118 )
2021	2021	BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA	2200 VINE ST BOX 830861	LINCOLN	NE	68503	LANCASTER	USA	International Research and Research Training	001	6	5/14/2021	COMPETING CONTINUATION	$287,118
2021	2020	BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA	2200 VINE ST BOX 830861	LINCOLN	NE	68503	LANCASTER	USA	International Research and Research Training	000	5	5/14/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $287,118

Issue Date FY: 2020 ( Subtotal = $299,045 )
2020	2020	BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA	2200 VINE ST BOX 830861	LINCOLN	NE	68503	LANCASTER	USA	International Research and Research Training	000	5	3/6/2020	NON-COMPETING CONTINUATION	$299,045
														Subtotal = $299,045

Issue Date FY: 2019 ( Subtotal = $281,741 )
2019	2019	BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA	2200 VINE ST BOX 830861	LINCOLN	NE	68503	LANCASTER	USA	International Research and Research Training	000	4	3/5/2019	NON-COMPETING CONTINUATION	$281,741
														Subtotal = $281,741

Issue Date FY: 2018 ( Subtotal = $300,162 )
2018	2018	BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA	2200 VINE ST BOX 830861	LINCOLN	NE	68503	LANCASTER	USA	International Research and Research Training	000	3	2/17/2018	NON-COMPETING CONTINUATION	$300,162
														Subtotal = $300,162

Issue Date FY: 2017 ( Subtotal = $298,898 )
2017	2017	BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA	2200 VINE ST BOX 830861	LINCOLN	NE	68503	LANCASTER	USA	International Research and Research Training	000	2	2/27/2017	NON-COMPETING CONTINUATION	$298,898
														Subtotal = $298,898

Issue Date FY: 2016 ( Subtotal = $302,669 )
2016	2016	UNIVERSITY OF NEBRASKA LINCOLN	303 ADMINISTRATION BUILDING	LINCOLN	NE	68588	LANCASTER	USA	International Research and Research Training	000	1	4/8/2016	NEW	$302,669
2016	2016	UNIVERSITY OF NEBRASKA LINCOLN	303 ADMINISTRATION BUILDING	LINCOLN	NE	68588	LANCASTER	USA	International Research and Research Training	001	1	7/11/2016	NEW	$0
														Subtotal = $302,669

Grand Total All Awards = $2,794,520

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AIDS Malignancies Training and Research International Program (AMTRIP)

Award Number: D43TW010354

ORGANIZATION: FOGARTY INTERNATIONAL CENTER

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 02/01/2022

PERIOD OF PERFORMANCE END DATE: 03/31/2026

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