Thursday, November 21, 2024 11/21/2024

Children's Oncology Group NCI Community Oncology Research Program (NCORP) Research Base grant

Award Number: UG1CA189955
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Project Summary The prognosis for children with cancer has improved dramatically over the past decades with an overall 5-year survival rate now at 84%. However, the late effects of cancer treatment, including permanent organ and tissue damage, hormonal and reproductive dysfunction and second cancers, are of special concern, with more than 40% of the estimated 360,000 survivors of childhood cancer experiencing a significant health-related quality of life complication from childhood cancer and its treatment. In addition, progress for a number of childhood cancers remains limited with approximately 50% of children with acute myelogenous leukemia, 50% of children with high-risk neuroblastoma, and more than 90% of children with brainstem glioma, still succumbing to their disease. The Children’s Oncology Group (COG), the world’s largest organization devoted exclusively to childhood and adolescent cancer research, and its multidisciplinary research teams comprised of more than 9,000 members, conducts research at more than 220 leading children’s hospitals, universities, and cancer centers. This proposal is for the COG NCI Community Oncology Research Program (NCORP) Research Base to continue its collaborative research work for our 26 community and 16 minority/underserved NCORP sites. With COG’s significant scientific, statistical, data management and information technology infrastructure, we seek to conduct pediatric clinical trials to define optimal treatments, and conduct laboratory research that will translate into more effective treatments with reduced side effects. The COG directly addresses the NCORP goals of providing access to state-of-the-art cancer treatment at community sites while conducting research in cancer control, including post-treatment surveillance/survivorship, and cancer care delivery. We promote the participation of community-based investigators in all of COG’s research, governance and administration and in NCORP Network activities. The COG’s research goals are to reduce overall mortality and morbidity, decrease acute and delayed treatment-related toxicities, and develop more effective ways of delivering care to children, adolescents and young adults. The COG NCORP Research Base is uniquely positioned to elucidate the impact of different health care delivery characteristics on outcomes, to identify determinants of poorer outcomes in underserved groups including adolescents and young adults, and to develop targeted strategies aimed at eliminating disparities and improving efficiencies for the delivery of cancer care in young persons with cancer.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $4,597,748 )
2024	2024	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 600	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Control	003	11	7/29/2024	NON-COMPETING CONTINUATION	$2,973,582
2024	2024	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 600	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Treatment Research	004	11	8/1/2024	SUPPLEMENT FOR EXPANSION	$1,421,697
2024	2024	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 600	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Control	005	11	8/9/2024	SUPPLEMENT FOR EXPANSION	$202,469
2024	2023	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 600	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Control	002	10	5/6/2024	NON-COMPETING CONTINUATION	$0
2024	2023	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 600	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Control	000	10	11/8/2023	SUPPLEMENT FOR EXPANSION	$0
2024	2023	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 600	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Control	001	10	4/26/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $4,597,748

Issue Date FY: 2023 ( Subtotal = $7,582,576 )
2023	2023	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 600	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Control	007	10	9/20/2023	SUPPLEMENT FOR EXPANSION	-$23,573
2023	2023	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 600	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Control	006	10	9/19/2023	SUPPLEMENT FOR EXPANSION	$202,469
2023	2023	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 600	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Control	004	10	8/8/2023	NON-COMPETING CONTINUATION	$5,903,680
2023	2023	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 600	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Treatment Research	005	10	8/10/2023	SUPPLEMENT FOR EXPANSION	$1,500,000
2023	2022	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 600	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Control	002	9	4/26/2023	NON-COMPETING CONTINUATION	$0
2023	2022	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 600	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Treatment Research	000	9	10/21/2022	SUPPLEMENT FOR EXPANSION	$0
2023	2021	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 600	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Control	003	8	7/14/2023	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$1,220
2023	2020	CHILDREN'S HOSPITAL OF PHILADELPHIA, THE	3401 CIVIC CENTER BLVD	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cancer Control	001	7	2/2/2023	NON-COMPETING CONTINUATION	-$1,220
														Subtotal = $7,582,576

Issue Date FY: 2022 ( Subtotal = $5,028,903 )
2022	2022	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 600	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Control	007	9	7/29/2022	NON-COMPETING CONTINUATION	$3,314,492
2022	2022	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 600	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Treatment Research	009	9	8/30/2022	SUPPLEMENT FOR EXPANSION	$1,500,000
2022	2022	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 600	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Control	008	9	8/9/2022	NON-COMPETING CONTINUATION	$215,084
2022	2021	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 290	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Control	004	8	6/6/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2022	2021	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 600	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Control	003	8	2/11/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$3,741,638
2022	2020	CHILDREN'S HOSPITAL OF PHILADELPHIA, THE	3401 CIVIC CENTER BLVD	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cancer Control	000	7	2/11/2022	NON-COMPETING CONTINUATION	-$2,792,752
2022	2020	CHILDREN'S HOSPITAL OF PHILADELPHIA, THE	3401 CIVIC CENTER BLVD	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cancer Control	002	7	2/11/2022	SUPPLEMENT FOR EXPANSION	-$449,700
2022	2020	CHILDREN'S HOSPITAL OF PHILADELPHIA, THE	3401 CIVIC CENTER BLVD	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cancer Treatment Research	001	7	2/11/2022	SUPPLEMENT FOR EXPANSION	-$499,186
2022	2018	CHILDREN'S HOSPITAL OF PHILADELPHIA, THE	3401 CIVIC CENTER BLVD	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cancer Treatment Research	006	5	6/29/2022	NON-COMPETING CONTINUATION	-$673
2022	2017	CHILDREN'S HOSPITAL OF PHILADELPHIA, THE	3401 CIVIC CENTER BLVD	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cancer Treatment Research	005	4	6/29/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $5,028,903

Issue Date FY: 2021 ( Subtotal = $5,792,964 )
2021	2021	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 290	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Control	003	8	9/20/2021	SUPPLEMENT FOR EXPANSION	$749,652
2021	2021	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 290	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Treatment Research	002	8	9/17/2021	SUPPLEMENT FOR EXPANSION	$499,186
2021	2021	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 290	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Control	004	8	9/21/2021	SUPPLEMENT FOR EXPANSION	$725,002
2021	2021	PUBLIC HEALTH INSTITUTE	555 12TH ST STE 290	OAKLAND	CA	94607	ALAMEDA	USA	Cancer Control	000	8	9/16/2021	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$3,819,124
2021	2020	CHILDREN'S HOSPITAL OF PHILADELPHIA, THE	3401 CIVIC CENTER BLVD	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cancer Control	001	7	9/17/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $5,792,964

Issue Date FY: 2020 ( Subtotal = $6,410,373 )
2020	2020	CHILDREN'S HOSPITAL OF PHILADELPHIA, THE	3401 CIVIC CENTER BLVD	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cancer Control	006	7	9/17/2020	SUPPLEMENT FOR EXPANSION	$449,700
2020	2020	CHILDREN'S HOSPITAL OF PHILADELPHIA, THE	3401 CIVIC CENTER BLVD	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cancer Treatment Research	004	7	8/21/2020	SUPPLEMENT FOR EXPANSION	$499,186
2020	2020	CHILDREN'S HOSPITAL OF PHILADELPHIA, THE	3401 CIVIC CENTER BLVD	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cancer Control	005	7	9/16/2020	NON-COMPETING CONTINUATION	$222,650
2020	2020	CHILDREN'S HOSPITAL OF PHILADELPHIA, THE	3401 CIVIC CENTER BLVD	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cancer Control	003	7	8/20/2020	NON-COMPETING CONTINUATION	$5,238,837
2020	2019	CHILDREN'S HOSPITAL OF PHILADELPHIA, THE	3401 CIVIC CENTER BLVD	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cancer Control	002	6	2/21/2020	COMPETING CONTINUATION	$779,811
2020	2019	CHILDREN'S HOSPITAL OF PHILADELPHIA, THE	3401 CIVIC CENTER BLVD	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cancer Control	000	6	12/31/2019	COMPETING CONTINUATION	$0
2020	2018	CHILDREN'S HOSPITAL OF PHILADELPHIA, THE	3401 CIVIC CENTER BLVD	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cancer Treatment Research	001	5	2/21/2020	NON-COMPETING CONTINUATION	-$779,811
														Subtotal = $6,410,373

Issue Date FY: 2019 ( Subtotal = $4,610,801 )
2019	2019	CHILDREN'S HOSPITAL OF PHILADELPHIA, THE	3401 CIVIC CENTER BLVD	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cancer Control	000	6	9/2/2019	COMPETING CONTINUATION	$4,610,801
														Subtotal = $4,610,801

Issue Date FY: 2018 ( Subtotal = $3,037,489 )
2018	2018	CHILDREN'S HOSPITAL OF PHILADELPHIA, THE	3401 CIVIC CENTER BLVD	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cancer Treatment Research	000	5	8/1/2018	NON-COMPETING CONTINUATION	$3,037,489
														Subtotal = $3,037,489

Issue Date FY: 2017 ( Subtotal = $3,690,706 )
2017	2017	CHILDREN'S HOSPITAL OF PHILADELPHIA, THE	3401 CIVIC CENTER BLVD	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cancer Treatment Research	000	4	7/26/2017	NON-COMPETING CONTINUATION	$3,690,706
														Subtotal = $3,690,706

Issue Date FY: 2016 ( Subtotal = $3,231,233 )
2016	2016	CHILDREN'S HOSPITAL OF PHILADELPHIA	34TH ST & CIVIC CENTER BLVD	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cancer Treatment Research	001	3	8/5/2016	NON-COMPETING CONTINUATION	-$730,002
2016	2016	CHILDREN'S HOSPITAL OF PHILADELPHIA	34TH ST & CIVIC CENTER BLVD	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cancer Treatment Research	000	3	8/1/2016	NON-COMPETING CONTINUATION	$3,961,235
														Subtotal = $3,231,233

Grand Total All Awards = $51,905,263

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Children's Oncology Group NCI Community Oncology Research Program (NCORP) Research Base grant

Award Number: UG1CA189955

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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