| | | | | | | | | | | | | | | | |
| | |
 | Issue Date FY: 2024 ( Subtotal = $53,510,192 ) (Continued on the next page) |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K02NS112600 | Joint analysis of genomic and electronic medical record data to assess outcomes and drug response in pediatric epilepsies | 000 | 5 | NIH | 2/19/2024 | $271,308 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U01DK135002 | Assessing Diabetes Risk Origins in Teens (ADROIT) | 000 | 2 | NIH | 2/29/2024 | $779,139 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R21MH131932 | Role of locus coeruleus-paraventricular thalamic projections in social threat processing | 000 | 2 | NIH | 1/26/2024 | $196,906 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08CA277013 | Optimizing outcomes for children and young adults with relapse of B-cell acute lymphoblastic leukemia after CD19-targeted chimeric antigen receptor T-cell therapy | 001 | 2 | NIH | 1/16/2024 | $179,076 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS126469 | Eye as a Window into Brain Health in Pediatric Hydrocephalus | 001 | 2 | NIH | 4/12/2024 | $49,318 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS126469 | Eye as a Window into Brain Health in Pediatric Hydrocephalus | 000 | 2 | NIH | 3/11/2024 | $634,118 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL161583 | Laryngotracheal Reconstruction with Engineered Cartilage | 000 | 2 | NIH | 2/7/2024 | $578,805 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DE032332 | Functional analysis of ESRP1/2 and CTNND1 gene variants in orofacial cleft | 001 | 2 | NIH | 1/10/2024 | $605,720 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL OF PHILADELPHIA, THE | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R21AI174545 | Exploring a Functional Role of Chromosome Loop Extrusion Direction on Regulating Genome Biology | 000 | 2 | NIH | 10/25/2023 | $240,300 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DK134717 | Vitamin D control of calorie allocation to muscle | 000 | 2 | NIH | 2/16/2024 | $463,307 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DK133453 | Leveraging early-life microbes to prevent type 1 diabetes | 001 | 2 | NIH | 3/20/2024 | $84,989 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DK133453 | Leveraging early-life microbes to prevent type 1 diabetes | 000 | 2 | NIH | 3/19/2024 | $663,514 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS131512 | A computational phenotyping approach to characterize neurogenetic disorders | 000 | 2 | NIH | 3/19/2024 | $644,590 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS127830 | Subgroup delineation in genetic epilepsies and developmental brain disorders | 000 | 2 | NIH | 3/19/2024 | $646,768 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS126541 | Glial metabolic status regulates axon regeneration in the central nervous system | 000 | 2 | NIH | 4/9/2024 | $560,837 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R03HD108387 | Understanding organizational culture and implementation of evidence-based resuscitation practices | 000 | 2 | NIH | 1/12/2024 | $80,100 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AG077911 | Illuminating adipo-osteoprogenitors in the bone marrow | 000 | 2 | NIH | 2/7/2024 | $415,678 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL OF PHILADELPHIA, THE | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL162715 | Impact of Obesity on Lung Macrophage Metabolism and Inflammation | 000 | 2 | NIH | 11/13/2023 | $533,991 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL OF PHILADELPHIA, THE | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R21MH131944 | Orexins actions in adolescence | 000 | 2 | NIH | 11/15/2023 | $198,000 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23DK131331 | IMPAKT Study: Imaging Modalities in Pediatric Assessments of Kidney Transplants | 000 | 3 | NIH | 3/18/2024 | $179,036 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS120099 | INJURY-INDUCED SPATIAL MEMORY IMPAIRMENTS ARE LINKED TO UNCOORDINATED HIPPOCAMPAL NEURONAL FIRING | 000 | 3 | NIH | 1/16/2024 | $396,000 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS122887 | Mechanistically-oriented therapy for a progressive myoclonus epilepsy | 000 | 3 | NIH | 3/4/2024 | $457,055 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS124640 | p38 MAPK activation as a therapeutic target for Friedreich ataxia | 000 | 3 | NIH | 3/5/2024 | $517,240 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL160748 | Preserving Genome Integrity In AAV-Mediated Gene Therapy | 000 | 3 | NIH | 1/31/2024 | $580,716 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL OF PHILADELPHIA, THE | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23HL161309 | Understanding longitudinal microbiome change in relation to immunologic outcomes in pediatric SCT recipients. | 000 | 3 | NIH | 12/14/2023 | $185,652 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | DP2AI164319 | Engineering synthetic cellular crosstalk for transplantation tolerance | 000 | 3 | NIH | 1/25/2024 | $474,500 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA262260 | A stalled chromatin regulatory network that mediates the oncogenic activity of Meningioma-1 | 001 | 3 | NIH | 4/17/2024 | $21,924 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA262260 | A stalled chromatin regulatory network that mediates the oncogenic activity of Meningioma-1 | 000 | 3 | NIH | 3/22/2024 | $394,632 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL OF PHILADELPHIA, THE | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08DK128606 | Novel gene discovery in disorders of the liver and biliary tree | 000 | 3 | NIH | 11/16/2023 | $163,836 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08NS119797 | Interrogation and Modulation of the Epigenome after Prenatal Hypoxic Brain Injury | 000 | 3 | NIH | 3/5/2024 | $215,523 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA258524 | Tracking Peripheral T-Cell Repertoire Changes for Preoperative and Early Ovarian Cancer Diagnosis | 005 | 4 | NIH | 4/16/2024 | $32,993 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA258524 | Tracking Peripheral T-Cell Repertoire Changes for Preoperative and Early Ovarian Cancer Diagnosis | 004 | 4 | NIH | 2/2/2024 | $593,871 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA269788 | IDP mediated transcriptional stabilization as a cause of AML | 000 | 3 | NIH | 4/3/2024 | $37,818 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA271523 | Novel Regulation of Oncogenic NRAS Signaling in Myeloid Malignancies | 001 | 3 | NIH | 4/10/2024 | $27,367 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA271523 | Novel Regulation of Oncogenic NRAS Signaling in Myeloid Malignancies | 000 | 3 | NIH | 3/13/2024 | $492,582 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01EB031284 | Infant Atlas of Brain Perfusion | 000 | 3 | NIH | 2/6/2024 | $528,516 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AR079822 | Immunological, serologic, and imaging biomarker predictors of flare in pediatric spondyloarthritis | 000 | 3 | NIH | 3/6/2024 | $349,825 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01LM013526 | Situation Awareness to Improve Infant Sepsis Recognition in the Presence of Clinical Uncertainty | 000 | 4 | NIH | 4/15/2024 | $332,608 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01MH125958 | Optimized Affective Computing Measures of Social Processes and Negative Valence in Youth Psychopathology | 000 | 4 | NIH | 1/31/2024 | $748,809 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01MH122465 | Sustainment of Mental Health Supports in Under-Resourced Urban Schools | 000 | 4 | NIH | 1/29/2024 | $725,808 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23HL153759 | The Roles of Pulmonary Hypertension and Right Ventricular Dysfunction in Pediatric Acute Respiratory Distress Syndrome | 000 | 4 | NIH | 4/3/2024 | $172,771 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HG013355 | Utilizing long-read sequencing to resolve inconclusive diagnoses and uncertainty in genetic testing | 000 | 1 | NIH | 4/1/2024 | $400,500 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | P30HS029755 | PEDSnet Scholars: A National Pediatric Learning Health System Embedded Scientist Training and Research Program | 001 | 1 | AHRQ | 1/10/2024 | -$968,100 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL OF PHILADELPHIA, THE | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | P30HS029755 | PEDSnet Scholars: A National Pediatric Learning Health System Embedded Scientist Training and Research Program | 000 | 1 | AHRQ | 12/27/2023 | $968,100 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | P30HS029755 | PEDSnet Scholars: A National Pediatric Learning Health System Embedded Scientist Training and Research Program | 001 | 1 | AHRQ | 1/10/2024 | $968,100 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI182049 | The B22 family of orthopoxvirus virulence factors: Investigating structure/function of these potent, multifaceted immunoevasins | 000 | 1 | NIH | 2/6/2024 | $668,007 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | F32DK138739 | Real-world Effectiveness and Utilization of Glucagon-Like Peptide-1 Receptor Agonists for Treatment of Type 2 Diabetes in Adolescents and Young Adults | 001 | 1 | NIH | 2/29/2024 | $0 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | F32DK138739 | Real-world Effectiveness and Utilization of Glucagon-Like Peptide-1 Receptor Agonists for Treatment of Type 2 Diabetes in Adolescents and Young Adults | 000 | 1 | NIH | 2/29/2024 | $85,304 |
| | 2024 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01MH134965 | 2/2 - Neurodevelopmental Trajectories in 22q11.2 Deletion Syndrome in Adolescence and Young Adulthood | 000 | 1 | NIH | 2/13/2024 | $435,881 |
|
