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 | Issue Date FY: 2026 ( Subtotal = $242,845,065 ) (Continued on the next page) |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI194422 | Genetics-based discovery of novel genes regulating follicular helper T cell function | 000 | 1 | NIH | 7/8/2026 | $906,255 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K25HL186164 | Computational and Experimental Investigations of Deformation-Driven Molecular Pathways in Single Right Ventricle Congenital Heart Disease | 000 | 1 | NIH | 7/8/2026 | $115,584 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DK141778 | Urinary peptidomics for neurogenic bladder risk stratification in patients with spina bifida | 000 | 1 | NIH | 2/6/2026 | $796,742 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R21DA065088 | Antioxidant and blood flow profiling in individuals with HIV | 001 | 1 | NIH | 3/11/2026 | $0 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | F32AR088407 | Investigating the role of Tfam-mediated mitochondrial respiration in osteoblastogenesis | 000 | 1 | NIH | 9/1/2026 | $76,300 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08DE035951 | Mapping the developmental effects of TBCK loss in dental and craniofacial mineralization | 000 | 1 | NIH | 7/8/2026 | $162,508 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R03HD122148 | Disease trajectories of rare genomic variants contributing to lesional brain disorders | 000 | 1 | NIH | 5/14/2026 | $356,000 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R50CA293895 | Development and deployment of computational methods to create novel immunotherapies for children with cancer | 000 | 1 | NIH | 8/27/2026 | $181,610 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | F32AR088407 | Investigating the role of Tfam-mediated mitochondrial respiration in osteoblastogenesis | 001 | 1 | NIH | 9/1/2026 | $0 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL183262 | Unlocking the potential of wearable sensors to measure physical activity and predict clinical worsening in pediatric pulmonary hypertension | 000 | 1 | NIH | 8/13/2026 | $1,068,774 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DK144396 | Real-world Comparative Treatment Effectiveness and Surrogate Outcome Evaluation in Membranous Nephropathy using Observational Data | 000 | 1 | NIH | 5/19/2026 | $949,759 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DK145431 | Defining bone marrow factors that support neonatalhematopoiesis | 000 | 1 | NIH | 8/25/2026 | $853,295 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA300077 | Bioinspired virus-like nanovaccines boost CAR T and endogenous T cells in tandem against solid tumors with antigen heterogeneity | 000 | 1 | NIH | 5/19/2026 | $737,082 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R21NS147239 | Understanding the Role of BLOC1S1 in Myelin Development | 000 | 1 | NIH | 4/28/2026 | $489,500 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | UM454988 | Autism Research Consortium | 02 | 2 | HRSA | 9/9/2026 | $0 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | UM454988 | Autism Research Consortium | 01 | 2 | HRSA | 9/3/2026 | $0 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | UM454988 | Autism Research Consortium | 00 | 2 | HRSA | 7/28/2026 | $1,161,404 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS131512 | A computational phenotyping approach to characterize neurogenetic disorders | 000 | 4 | NIH | 4/7/2026 | $688,207 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI185544 | High Resolution, Whole Genome Tracking of Pathogen Transmission and Infection in the Neonatal ICU (NICU) | 000 | 2 | NIH | 6/18/2026 | $873,921 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA193776 | Improving risk allocation and developing novel therapies for children with T-ALL and T-LL | 001 | 9 | NIH | 4/17/2026 | $73,733 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA193776 | Improving risk allocation and developing novel therapies for children with T-ALL and T-LL | 000 | 9 | NIH | 1/27/2026 | $663,617 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23HD119673 | Neurocognitive Outcomes and the Trajectory of Recovery One-year After Pediatric Sepsis | 000 | 2 | NIH | 7/7/2026 | $155,432 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS144826 | Neurological pathophysiology of disrupted O-glycosylation in congenital disorders of glycosylation | 000 | 2 | NIH | 8/7/2026 | $686,889 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | F32HL175927 | Role of dietary fatty acids in shaping lung macrophage homeostasis and inflammatory function | 002 | 2 | NIH | 9/2/2026 | $82,348 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23HD119271 | Transplacental Antibiotic Exposures in Newborn Infants | 000 | 2 | NIH | 7/1/2026 | $159,976 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI187174 | Defining the role of enterococci in reshaping Clostridioides difficile infection | 000 | 2 | NIH | 7/15/2026 | $808,886 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | DP2AI192737 | Decoding multidrug-resistant pathogen dynamics for clinically-relevant wastewater surveillance | 000 | 2 | NIH | 7/7/2026 | $534,000 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08NS140553 | Defining JNK-associated neurodevelopmental disorders | 000 | 2 | NIH | 7/30/2026 | $221,400 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23HD113836 | Defining transmission pathways for sepsis-causing pathogens in low resource settings using microbiome methods and spatial epidemiology | 000 | 2 | NIH | 8/11/2026 | $155,185 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08HL173625 | Air pollution sensitivity in pediatric asthma | 001 | 2 | NIH | 6/18/2026 | $135,000 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08HL173625 | Air pollution sensitivity in pediatric asthma | 000 | 1 | NIH | 5/18/2026 | $47,234 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | OT2OD037960 | Multimodal machine learning for diagnosis and mechanistic phenotyping of inherited diseases | 002 | 1 | NIH | 6/3/2026 | $1,217,898 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R00NS135123 | Development of Distinct Areas in the Human Cerebral Cortex | 000 | 3 | NIH | 8/21/2026 | $249,001 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL180443 | Origins of neonatal lung myofibroblasts | 000 | 2 | NIH | 7/10/2026 | $582,691 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23NS140491 | Outcome measures and quantitative EEG biomarkers in SYNGAP1-related disorders | 000 | 2 | NIH | 8/7/2026 | $218,713 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23HL177271 | Developing a framework for designing the next generation of pediatric ARDS trials | 000 | 2 | NIH | 8/3/2026 | $180,001 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA271523 | Novel Regulation of Oncogenic NRAS Signaling in Myeloid Malignancies | 000 | 5 | NIH | 3/4/2026 | $547,313 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA273328 | Re-Engaging AYA Survivors in Cancer-Related Healthcare (REACH): A Sequential Multiple Assignment Randomized Trial (SMART) | 000 | 4 | NIH | 3/30/2026 | $715,901 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL177014 | Endothelial cell targeting of factor VIII for hemophilia A | 000 | 2 | NIH | 8/13/2026 | $857,161 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | DP1DA063517 | Lifespan effects of prenatal and perinatal opioid exposure on the brain's metabolic-epigenetic axis | 000 | 2 | NIH | 6/3/2026 | $534,000 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA258524 | Tracking Peripheral T-Cell Repertoire Changes for Preoperative and Early Ovarian Cancer Diagnosis | 001 | 6 | NIH | 4/16/2026 | $83,785 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA258524 | Tracking Peripheral T-Cell Repertoire Changes for Preoperative and Early Ovarian Cancer Diagnosis | 000 | 6 | NIH | 1/16/2026 | $754,071 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | P01CA217959 | Discovering and Exploiting Mechanisms of Neuroblastoma Therapy Resistance | 000 | 8 | NIH | 4/27/2026 | $2,450,350 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AR061758 | Pathogenic Mechanisms in Hereditary Multiple Exostoses Syndrome | 001 | 15 | NIH | 5/14/2026 | $19,360 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R00HL177827 | Determining genetic mechanisms that drive in vitro hematopoiesis | 000 | 2 | NIH | 8/10/2026 | $445,000 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AR061758 | Pathogenic Mechanisms in Hereditary Multiple Exostoses Syndrome | 000 | 15 | NIH | 3/31/2026 | $348,480 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HD114705 | Comprehensive identification and functional study of Esrp-regulated isoforms during epithelial-mesenchymal transition. | 000 | 2 | NIH | 2/26/2026 | $756,436 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL179221 | Proteolytic Regulation of Factor VIII Before and After Activation | 000 | 2 | NIH | 6/23/2026 | $646,626 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08DK146197 | Elucidating the role of interleukin-22 in Hirschsprung Associated enterocolitis pathogenesis | 000 | 1 | NIH | 1/14/2026 | $159,288 |
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