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 | Issue Date FY: 2025 ( Subtotal = $17,547,736 ) (Continued on the next page) |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R03CA293992 | Long-read, single-cell RNA sequencing of high-risk neuroblastoma samples | 000 | 1 | NIH | 12/16/2024 | $178,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23HL161309 | Understanding longitudinal microbiome change in relation to immunologic outcomes in pediatric SCT recipients. | 000 | 4 | NIH | 12/10/2024 | $185,652 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS120099 | INJURY-INDUCED SPATIAL MEMORY IMPAIRMENTS ARE LINKED TO UNCOORDINATED HIPPOCAMPAL NEURONAL FIRING | 000 | 4 | NIH | 11/29/2024 | $396,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL162715 | Impact of Obesity on Lung Macrophage Metabolism and Inflammation | 000 | 3 | NIH | 11/26/2024 | $540,803 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R03CA287169 | Identification and characterization of genetic risk factors in pediatric brain tumors | 000 | 2 | NIH | 11/25/2024 | $178,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U01TR005355 | Personalized prime editing as a platform for hepatic inborn errors of metabolism | 000 | 1 | NIH | 11/27/2024 | $1,427,560 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23DK134847 | Physical Activity and Muscle Strength in Pediatric CKD | 000 | 2 | NIH | 12/3/2024 | $182,197 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08DK128606 | Novel gene discovery in disorders of the liver and biliary tree | 000 | 4 | NIH | 11/1/2024 | $163,836 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI147118 | Mechanobiology of the immune synapse: signal integration via actin dynamics | 000 | 9 | NIH | 11/1/2024 | $413,263 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R21AI182619 | Potent Signal 1 as a noncanonical Signal 3: antigen location, and peptide:MHCII complex density and half-life as drivers of CD4+ T cell differentiation | 000 | 1 | NIH | 11/21/2024 | $267,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DK112955 | Repurposing rifampin to reduce elevated levels of blood and urine calcium in patients with inactivating mutations of CYP24A1 | 000 | 8 | NIH | 11/20/2024 | $657,228 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08AI151265 | Functions for novel IL-15-responsive macrophages in the uterus during pregnancy | 000 | 5 | NIH | 11/14/2024 | $185,328 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI187335 | Manipulation of the DNA damage response and the proteome on viral genomes during Herpes Simplex Virus (HSV) infection | 000 | 1 | NIH | 11/14/2024 | $651,832 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI181999 | Cul5 regulates lung ILC2 cells during helminth infection | 000 | 1 | NIH | 11/14/2024 | $659,341 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI172841 | Pathogenicity of the emerging pathogen Kingella kingae | 000 | 3 | NIH | 10/31/2024 | $445,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01MH107506 | A longitudinal study of brain development in children with autism | 001 | 8 | NIH | 11/15/2024 | $68,484 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01MH107506 | A longitudinal study of brain development in children with autism | 000 | 8 | NIH | 11/12/2024 | $75,426 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DK118155 | Intersection of signaling pathways and transcription factors regulating islet development | 001 | 7 | NIH | 12/12/2024 | $563,705 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AG077911 | Illuminating adipo-osteoprogenitors in the bone marrow | 000 | 3 | NIH | 12/20/2024 | $415,678 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | T2331579 | Children's Hospitals Graduate Medical Education Payment Program | 00 | 8 | HRSA | 12/9/2024 | $1,167,227 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | T2331579 | Children's Hospitals Graduate Medical Education Payment Program | 00 | 8 | HRSA | 12/9/2024 | $3,426,155 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS137604 | A developmental mechanism of temperature-sensitive seizures towards therapeutic manipulation | 000 | 1 | NIH | 12/28/2024 | $596,146 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01MH138428 | Intergenerational transmission of threat sensitivity as an risk marker for psychopathology in young children | 000 | 1 | NIH | 12/18/2024 | $681,690 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI179680 | The molecular circuits controlling human T follicular regulatory cell development | 000 | 1 | NIH | 12/9/2024 | $781,685 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23HL151381 | Leveraging implementation and behavioral science to reduce harmful overuse of diagnostic testing in critically ill children | 000 | 5 | NIH | 12/10/2024 | $175,519 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01MH134965 | 2/2 - Neurodevelopmental Trajectories in 22q11.2 Deletion Syndrome in Adolescence and Young Adulthood | 000 | 2 | NIH | 12/10/2024 | $411,666 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08AI182477 | Modeling and prediction of allergic trajectories in children | 000 | 1 | NIH | 12/4/2024 | $151,444 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI182049 | The B22 family of orthopoxvirus virulence factors: Investigating structure/function of these potent, multifaceted immunoevasins | 000 | 2 | NIH | 12/10/2024 | $719,964 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R13EB037422 | Body MRI: Unsolved Problems & Unmet Needs | 000 | 1 | NIH | 12/30/2024 | $10,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01EB031284 | Infant Atlas of Brain Perfusion | 000 | 4 | NIH | 12/31/2024 | $535,678 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AR083903 | Regulation of Skeletal Growth and Regeneration | 000 | 1 | NIH | 12/31/2024 | $378,250 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL177971 | Lymphatic Dysfunction and Development of Post-Transplant Obliterative Bronchiolitis | 000 | 1 | NIH | 12/25/2024 | $750,162 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DK141691 | Mechanistic human studies to prevent Hirschsprung-associated enterocolitis | 000 | 1 | NIH | 12/27/2024 | $722,908 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | P30HS029755 | PEDSnet Scholars: A National Pediatric Learning Health System Embedded Scientist Training and Research Program | 000 | 2 | AHRQ | 12/23/2024 | $973,541 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI187202 | Chronic STAT3 signaling in STAT3 GOF causes CD8 T cell dysfunction via CD39 upregulation | 000 | 1 | NIH | 12/20/2024 | $658,426 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS110869 | Interneuron axonopathy underlies circuit dysfunction in a mouse model of Dravet syndrome | 001 | 6 | NIH | 12/18/2024 | $645,791 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R03CA293992 | Long-read, single-cell RNA sequencing of high-risk neuroblastoma samples | 001 | 1 | NIH | 12/26/2024 | $0 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS119977 | Pathomechanisms of SCN3A-related neurodevelopmental disorder | 000 | 5 | NIH | 11/20/2024 | $466,472 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | F32DA062486 | Targeting Dentate Gyrus to Disrupt Fentanyl-Linked Context Memories | 000 | 1 | NIH | 12/16/2024 | $76,756 |
| | 2025 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U2CHL156291 | Integrating Imaging-based Infrastructure into the INCLUDE Data Hub | 000 | 5 | NIH | 11/26/2024 | $0 |
| | 2025 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL168066 | Multidimensional phenotype classification in grade 3 BPD | 000 | 2 | NIH | 11/28/2024 | $0 |
| | 2025 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R35GM134863 | Mitochondrial respiratory chain disease mechanistic and therapeutic modeling | 000 | 5 | NIH | 11/8/2024 | $0 |
| | 2025 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA275767 | PET Biomarker for synaptic density changes after radiation therapy | 000 | 1 | NIH | 11/13/2024 | $0 |
| | 2025 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23MH119976 | Health Coaching to Improve Comprehensive HIV and Sexually Transmitted Infection Prevention in Adolescent Primary Care | 000 | 5 | NIH | 10/24/2024 | -$58,495 |
| | 2025 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08DK131253 | Dissecting the mechanisms behind biphasic beta cell disease caused by mutations in HNF1alpha | 000 | 4 | NIH | 10/9/2024 | $0 |
| | 2025 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA283058 | The interface of transcription, DNA damage and epigenetics: A therapeutic vulnerability of the EWS-FLI1 transcription factor | 000 | 2 | NIH | 11/5/2024 | -$429,113 |
| | 2025 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DK118155 | Intersection of signaling pathways and transcription factors regulating islet development | 000 | 6 | NIH | 10/18/2024 | $0 |
| | 2025 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | H9E53192 | Transition for Youth with Autism and/or Epilepsy Demonstration Projects | 01 | 1 | HRSA | 11/8/2024 | $0 |
| | 2025 | 2024 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | RL1HD107777 | Collaborative Pediatric Critical Care Research Network - Clinical Site | 000 | 4 | NIH | 10/11/2024 | $0 |
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