| | | | | | | | | | | | | | | | |
| | |
 | Issue Date FY: 2025 ( Subtotal = $58,097,824 ) (Continued on the next page) |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DK054937 | Transcriptional Networks Controlling Erythroid Differentiation | 000 | 26 | NIH | 4/18/2025 | $752,242 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AR061758 | Pathogenic Mechanisms in Hereditary Multiple Exostoses Syndrome | 000 | 14 | NIH | 3/14/2025 | $348,480 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA237562 | Elucidating the role of the noncoding genome in neuroblastoma | 000 | 5 | NIH | 3/14/2025 | $362,340 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA271523 | Novel Regulation of Oncogenic NRAS Signaling in Myeloid Malignancies | 000 | 4 | NIH | 3/14/2025 | $492,582 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA269788 | IDP mediated transcriptional stabilization as a cause of AML | 000 | 4 | NIH | 3/14/2025 | $212,790 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | P20DK140504 | Personalizing Outcomes of Nephrolithiasis in Youth (PONY) | 000 | 2 | NIH | 4/18/2025 | $391,028 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DK135871 | Early life bladder inflammatory events in female mice lead to subsequent LUTS in adulthood | 000 | 3 | NIH | 4/18/2025 | $570,212 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | F32AR085486 | Skeletal Patterning Orchestrated by RUNX2 and RUNX3 | 000 | 1 | NIH | 3/13/2025 | $73,828 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | T2331579 | Children's Hospitals Graduate Medical Education Payment Program | 01 | 8 | HRSA | 4/11/2025 | $1,167,227 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | T2331579 | Children's Hospitals Graduate Medical Education Payment Program | 01 | 8 | HRSA | 4/11/2025 | $3,426,155 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HD114705 | Comprehensive identification and functional study of Esrp-regulated isoforms during epithelial-mesenchymal transition. | 000 | 1 | NIH | 3/12/2025 | $763,886 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23HD115872 | Hospital Financial Health, NICU Strain, and Neonatal Outcome Variation and Subpopulation Disparities | 000 | 1 | NIH | 3/31/2025 | $160,052 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R25TR005269 | Predoctoral Preparatory Program (P3) in Translational Research | 000 | 2 | NIH | 4/1/2025 | $98,855 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23HL153759 | The Roles of Pulmonary Hypertension and Right Ventricular Dysfunction in Pediatric Acute Respiratory Distress Syndrome | 000 | 5 | NIH | 4/1/2025 | $176,799 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA262260 | A stalled chromatin regulatory network that mediates the oncogenic activity of Meningioma-1 | 000 | 4 | NIH | 3/18/2025 | $394,632 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R00HL177830 | NET stabilization: mechanistic and therapeutic studies studying the role of NETs in thromboinflammatory disease | 000 | 1 | NIH | 3/17/2025 | $445,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | NU65PS923759 | The Adolescent Initiative Mobile Health Team | 00 | 4 | CDC | 4/2/2025 | $400,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS127830 | Subgroup delineation in genetic epilepsies and developmental brain disorders | 001 | 3 | NIH | 3/31/2025 | $636,135 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI180250 | Defining the four major routes of MHC class II antigen processing and presentation with influenza antigens | 000 | 2 | NIH | 4/16/2025 | $598,313 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01MH132934 | The Genetics of Personalized Functional MRI Networks | 000 | 3 | NIH | 4/17/2025 | $713,048 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | P01CA217959 | Discovering and Exploiting Mechanisms of Neuroblastoma Therapy Resistance | 001 | 7 | NIH | 3/28/2025 | $2,202,503 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HG013355 | Utilizing long-read sequencing to resolve inconclusive diagnoses and uncertainty in genetic testing | 000 | 2 | NIH | 3/20/2025 | $400,500 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08AI151265 | Functions for novel IL-15-responsive macrophages in the uterus during pregnancy | 000 | 5 | NIH | 11/14/2024 | $185,328 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08AI182476 | Evaluating mRNA-lipid nanoparticle platforms and adjuvants to overcome maternal antibody interference | 000 | 1 | NIH | 1/9/2025 | $184,896 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI181999 | Cul5 regulates lung ILC2 cells during helminth infection | 000 | 1 | NIH | 11/14/2024 | $659,341 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI187335 | Manipulation of the DNA damage response and the proteome on viral genomes during Herpes Simplex Virus (HSV) infection | 000 | 1 | NIH | 11/14/2024 | $651,832 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DE033646 | Mechanisms of Macroglossia in Beckwith-Wiedemann Syndrome | 000 | 1 | NIH | 4/24/2025 | $818,112 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL161583 | Laryngotracheal Reconstruction with Engineered Cartilage | 000 | 3 | NIH | 3/25/2025 | $563,777 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL169401 | A precision therapy approach to red cell transfusion for sickle cell disease | 000 | 2 | NIH | 4/25/2025 | $715,949 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL160748 | Preserving Genome Integrity In AAV-Mediated Gene Therapy | 000 | 4 | NIH | 2/28/2025 | $580,716 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R25HD101365 | Advancing Child Health: Preparing the Next Generation of Pediatric Researchers | 000 | 5 | NIH | 4/25/2025 | $162,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL119479 | Regulation of Hemoglobin Switching | 001 | 12 | NIH | 2/28/2025 | $614,926 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA193776 | Improving risk allocation and developing novel therapies for children with T-ALL and T-LL | 000 | 8 | NIH | 2/28/2025 | $664,135 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HS029867 | CCC EQUATE (Equitable Quantification And Task Evaluation) | 000 | 2 | AHRQ | 3/24/2025 | $350,544 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS126541 | Glial metabolic status regulates axon regeneration in the central nervous system | 000 | 3 | NIH | 3/25/2025 | $512,301 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U01DK135002 | Assessing Diabetes Risk Origins in Teens (ADROIT) | 000 | 3 | NIH | 2/14/2025 | $749,173 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R37CA282041 | GPC2 CARs in neuroblastoma: Mechanisms of resistance and efficacy of next-generation constructs | 000 | 2 | NIH | 4/7/2025 | $562,834 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AR080062 | Transcriptional control of growth plate chondrocytes | 000 | 4 | NIH | 4/7/2025 | $529,312 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08CA277013 | Optimizing outcomes for children and young adults with relapse of B-cell acute lymphoblastic leukemia after CD19-targeted chimeric antigen receptor T-cell therapy | 000 | 3 | NIH | 2/14/2025 | $180,885 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01MH133843 | Precision brain charts for imaging-genomics of schizophrenia and the psychosis spectrum | 000 | 3 | NIH | 3/11/2025 | $663,129 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AR079822 | Immunological, serologic, and imaging biomarker predictors of flare in pediatric spondyloarthritis | 000 | 4 | NIH | 3/24/2025 | $364,553 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | F32AR085486 | Skeletal Patterning Orchestrated by RUNX2 and RUNX3 | 001 | 1 | NIH | 4/7/2025 | $0 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23HD109426 | The impact of delivery hospital organizational structure and culture on perinatal outcomes | 000 | 3 | NIH | 4/8/2025 | $155,196 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS131512 | A computational phenotyping approach to characterize neurogenetic disorders | 000 | 3 | NIH | 3/11/2025 | $631,987 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R03CA293992 | Long-read, single-cell RNA sequencing of high-risk neuroblastoma samples | 003 | 1 | NIH | 3/3/2025 | $0 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI103280 | MEP pathway resistance in Plasmodium falciparum | 000 | 13 | NIH | 3/11/2025 | $452,870 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DK133453 | Leveraging early-life microbes to prevent type 1 diabetes | 000 | 3 | NIH | 3/3/2025 | $658,400 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA259635 | Anti-tumor immunity and intestinal microbiota are modulated by mitochondrial DNA | 000 | 4 | NIH | 4/11/2025 | $571,766 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HD100421 | Effects of Sleep on Bone Density and Strength in Adolescence: A Prospective Longitudinal Study | 001 | 5 | NIH | 4/11/2025 | $65,161 |
|
