| | | | | | | | | | | | | | | | |
| | |
 | Issue Date FY: 2025 ( Subtotal = $62,924,584 ) (Continued on the next page) |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23NS124986 | Trigeminovascular sensitization in post-traumatic headache: electrophysiologic and blood biomarkers in youth | 000 | 4 | NIH | 5/2/2025 | $215,195 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA259635 | Anti-tumor immunity and intestinal microbiota are modulated by mitochondrial DNA | 000 | 4 | NIH | 4/11/2025 | $571,766 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23DK131331 | IMPAKT Study: Imaging Modalities in Pediatric Assessments of Kidney Transplants | 000 | 4 | NIH | 4/24/2025 | $178,948 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01EB031284 | Infant Atlas of Brain Perfusion | 000 | 4 | NIH | 12/31/2024 | $535,678 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23HD102526 | Maternal Resilience to Stress, Neonatal Outcomes, and Racial/Ethnic Health Disparities | 000 | 5 | NIH | 4/22/2025 | $158,651 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08DK128606 | Novel gene discovery in disorders of the liver and biliary tree | 000 | 4 | NIH | 11/1/2024 | $163,836 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01MH125958 | Optimized Affective Computing Measures of Social Processes and Negative Valence in Youth Psychopathology | 000 | 5 | NIH | 1/21/2025 | $695,590 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U01DK135002 | Assessing Diabetes Risk Origins in Teens (ADROIT) | 000 | 3 | NIH | 2/14/2025 | $749,173 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI184976 | Genetic determinates of SPI1 expression and activity in human germinal center B cells | 000 | 1 | NIH | 2/1/2025 | $820,623 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DK133453 | Leveraging early-life microbes to prevent type 1 diabetes | 000 | 3 | NIH | 3/3/2025 | $658,400 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | F32MH135724 | HIV and ART Disruptions in Glial Cell Lipid Metabolism and its Effect on Adolescent Myelination | 000 | 2 | NIH | 3/6/2025 | $84,592 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23HL153759 | The Roles of Pulmonary Hypertension and Right Ventricular Dysfunction in Pediatric Acute Respiratory Distress Syndrome | 000 | 5 | NIH | 4/1/2025 | $176,799 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R25HD101365 | Advancing Child Health: Preparing the Next Generation of Pediatric Researchers | 000 | 5 | NIH | 4/25/2025 | $162,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DE033646 | Mechanisms of Macroglossia in Beckwith-Wiedemann Syndrome | 000 | 1 | NIH | 4/24/2025 | $818,112 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HD116782 | Reducing Disparities in Access to High-level Neonatal Intensive Care and Neonatal Outcomes | 000 | 1 | NIH | 4/14/2025 | $736,279 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HD100421 | Effects of Sleep on Bone Density and Strength in Adolescence: A Prospective Longitudinal Study | 001 | 5 | NIH | 4/11/2025 | $65,161 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HD100421 | Effects of Sleep on Bone Density and Strength in Adolescence: A Prospective Longitudinal Study | 000 | 5 | NIH | 1/21/2025 | $586,448 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08AI151265 | Functions for novel IL-15-responsive macrophages in the uterus during pregnancy | 000 | 5 | NIH | 11/14/2024 | $185,328 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS119473 | Novel Ultrasound Indices of Intracranial Pressure and Brain Ischemia in Neonatal Hydrocephalus | 001 | 5 | NIH | 5/8/2025 | $701,154 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS122887 | Mechanistically-oriented therapy for a progressive myoclonus epilepsy | 000 | 4 | NIH | 4/9/2025 | $501,794 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS126469 | Eye as a Window into Brain Health in Pediatric Hydrocephalus | 000 | 3 | NIH | 5/1/2025 | $693,180 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01MH136706 | Linking mitochondrial and synaptic weakness to schizophrenia | 000 | 2 | NIH | 1/23/2025 | $552,074 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | P20DK140504 | Personalizing Outcomes of Nephrolithiasis in Youth (PONY) | 000 | 2 | NIH | 4/18/2025 | $391,028 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS120099 | INJURY-INDUCED SPATIAL MEMORY IMPAIRMENTS ARE LINKED TO UNCOORDINATED HIPPOCAMPAL NEURONAL FIRING | 000 | 4 | NIH | 11/29/2024 | $396,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL162715 | Impact of Obesity on Lung Macrophage Metabolism and Inflammation | 000 | 3 | NIH | 11/26/2024 | $540,803 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01MH134965 | 2/2 - Neurodevelopmental Trajectories in 22q11.2 Deletion Syndrome in Adolescence and Young Adulthood | 000 | 2 | NIH | 12/10/2024 | $411,666 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08HD111688 | Comprehensive Pediatric Phenotyping for Evidence-Based Diagnosis in Genetic Disease | 000 | 3 | NIH | 5/1/2025 | $148,824 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | P30HS029755 | PEDSnet Scholars: A National Pediatric Learning Health System Embedded Scientist Training and Research Program | 000 | 2 | AHRQ | 12/23/2024 | $973,541 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | DP2AI164319 | Engineering synthetic cellular crosstalk for transplantation tolerance | 000 | 4 | NIH | 1/17/2025 | $527,222 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R33GM146159 | Pediatric Sepsis Biorepository and Clinical Database | 000 | 4 | NIH | 4/11/2025 | $694,755 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | NU65PS923759 | The Adolescent Initiative Mobile Health Team | 00 | 4 | CDC | 4/2/2025 | $400,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL119479 | Regulation of Hemoglobin Switching | 001 | 12 | NIH | 2/28/2025 | $614,926 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R25TR005269 | Predoctoral Preparatory Program (P3) in Translational Research | 000 | 2 | NIH | 4/1/2025 | $98,855 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23HL151381 | Leveraging implementation and behavioral science to reduce harmful overuse of diagnostic testing in critically ill children | 000 | 5 | NIH | 12/10/2024 | $175,519 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS119977 | Pathomechanisms of SCN3A-related neurodevelopmental disorder | 000 | 5 | NIH | 11/20/2024 | $466,472 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI172841 | Pathogenicity of the emerging pathogen Kingella kingae | 000 | 3 | NIH | 10/31/2024 | $445,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS124640 | p38 MAPK activation as a therapeutic target for Friedreich ataxia | 000 | 4 | NIH | 4/28/2025 | $556,671 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01MH129970 | Behavioral pattern separation: orchestration by lateral entorhinal cortex-hippocampal circuitry | 000 | 3 | NIH | 3/27/2025 | $601,308 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AG077911 | Illuminating adipo-osteoprogenitors in the bone marrow | 000 | 3 | NIH | 12/20/2024 | $415,678 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23DK134847 | Physical Activity and Muscle Strength in Pediatric CKD | 000 | 2 | NIH | 12/3/2024 | $182,197 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS126541 | Glial metabolic status regulates axon regeneration in the central nervous system | 000 | 3 | NIH | 3/25/2025 | $512,301 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DK135871 | Early life bladder inflammatory events in female mice lead to subsequent LUTS in adulthood | 000 | 3 | NIH | 4/18/2025 | $570,212 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI180250 | Defining the four major routes of MHC class II antigen processing and presentation with influenza antigens | 000 | 2 | NIH | 4/16/2025 | $598,313 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI147118 | Mechanobiology of the immune synapse: signal integration via actin dynamics | 000 | 9 | NIH | 11/1/2024 | $413,263 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DE032332 | Functional analysis of ESRP1/2 and CTNND1 gene variants in orofacial cleft | 000 | 3 | NIH | 1/17/2025 | $551,976 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23HD109426 | The impact of delivery hospital organizational structure and culture on perinatal outcomes | 000 | 3 | NIH | 4/8/2025 | $155,196 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS127830 | Subgroup delineation in genetic epilepsies and developmental brain disorders | 001 | 3 | NIH | 3/31/2025 | $636,135 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R61NS130216 | Development of Translatable Neurophysiological Biomarkers to Accelerate Therapeutic Development in Rett Syndrome | 000 | 3 | NIH | 3/26/2025 | $701,399 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01MH122465 | Sustainment of Mental Health Supports in Under-Resourced Urban Schools | 000 | 5 | NIH | 1/28/2025 | $647,682 |
|
