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 | Issue Date FY: 2026 ( Subtotal = $113,484,895 ) (Continued on the next page) |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS120099 | INJURY-INDUCED SPATIAL MEMORY IMPAIRMENTS ARE LINKED TO UNCOORDINATED HIPPOCAMPAL NEURONAL FIRING | 000 | 5 | NIH | 12/16/2025 | $396,000 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL162715 | Impact of Obesity on Lung Macrophage Metabolism and Inflammation | 000 | 4 | NIH | 2/9/2026 | $549,173 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL162715 | Impact of Obesity on Lung Macrophage Metabolism and Inflammation | 001 | 4 | NIH | 3/25/2026 | $17,342 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DK134585 | Resolving Uncertainty in Alagille Syndrome Diagnostics | 000 | 4 | NIH | 5/26/2026 | $570,652 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23HL169833 | MIGHTIER: Movement in Heart Transplant patients: the Impact of Environmental factoRs | 001 | 3 | NIH | 6/11/2026 | $160,053 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | OT2CA297575 | MATCHMAKERS - Solving TCR recognition and design via integrated high-throughput screening, structural, functional, and computational approaches | 001 | 1 | NIH | 5/1/2026 | $434,021 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | DP2AI164319 | Engineering synthetic cellular crosstalk for transplantation tolerance | 000 | 5 | NIH | 1/15/2026 | $527,222 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01MH134965 | 2/2 - Neurodevelopmental Trajectories in 22q11.2 Deletion Syndrome in Adolescence and Young Adulthood | 000 | 3 | NIH | 1/21/2026 | $484,313 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R37AI067946 | Directing Function at the Natural Killer Cell Secretory Immunological Synapse | 001 | 17 | NIH | 12/30/2025 | $546,512 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R34MH132718 | Implementation strategies for caregiver and teacher use of behavioral interventions with ADHD: A pilot study | 000 | 3 | NIH | 7/1/2026 | $308,503 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HG013359 | Novel bioinformatics methods to detect DNA and RNA modifications using Nanopore long-read sequencing | 000 | 4 | NIH | 6/30/2026 | $714,861 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL119479 | Regulation of Hemoglobin Switching | 001 | 13 | NIH | 3/24/2026 | $20,497 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL119479 | Regulation of Hemoglobin Switching | 000 | 13 | NIH | 2/23/2026 | $649,089 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R25TR005269 | Predoctoral Preparatory Program (P3) in Translational Research | 000 | 3 | NIH | 6/16/2026 | $98,678 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL168066 | Multidimensional phenotype classification in grade 3 BPD | 000 | 4 | NIH | 7/6/2026 | $796,943 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA303081 | Characterization and targeting of HSPC-like blasts in high-risk leukemias | 000 | 1 | NIH | 7/3/2026 | $744,511 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HD117777 | Medicaid Enrollment and Outcomes Over the Reproductive Lifecourse | 000 | 2 | NIH | 6/30/2026 | $692,628 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R03DK147724 | Control of hemoglobin expression by the chromatin remodeler CHD7 | 000 | 1 | NIH | 5/7/2026 | $133,500 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08NS144513 | Striatal Interneuron Dysfunction: Uncovering the mechanistic basis of autism spectrum disorder in Dravet Syndrome | 000 | 1 | NIH | 5/11/2026 | $221,400 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23MH138754 | An Examination of Computational Learning Mechanisms Underlying Aberrant Food Approach in Youth with ARFID | 000 | 1 | NIH | 5/7/2026 | $170,024 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL180417 | Lessons from Hardikar Syndrome: MED12 as a novel regulator of vasculogenesis | 000 | 1 | NIH | 7/7/2026 | $889,804 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | AY2AX000199 | Realizing and Sustaining Personalized In Vivo Gene Editing Therapeutics | 000 | 1 | NIH | 7/6/2026 | $6,084,531 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DC023554 | Verbal and Non-Verbal Predictors of Successful Communication Within and Across Neurotype: Leveraging Context-Dependent, Next-Generation Digital Phenotyping | 000 | 1 | NIH | 5/18/2026 | $717,468 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA300077 | Bioinspired virus-like nanovaccines boost CAR T and endogenous T cells in tandem against solid tumors with antigen heterogeneity | 000 | 1 | NIH | 5/19/2026 | $737,082 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DK144396 | Real-world Comparative Treatment Effectiveness and Surrogate Outcome Evaluation in Membranous Nephropathy using Observational Data | 000 | 1 | NIH | 5/19/2026 | $949,759 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R21NS147239 | Understanding the Role of BLOC1S1 in Myelin Development | 000 | 1 | NIH | 4/28/2026 | $489,500 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R21CA299559 | Enhancing drug delivery to treat high-risk neuroblastoma | 000 | 1 | NIH | 3/27/2026 | $457,683 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI195638 | Role of the PilC1 and PilC2 pilus-associated proteins in Kingella kingae pathogenicity | 001 | 1 | NIH | 2/26/2026 | $19,500 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI195638 | Role of the PilC1 and PilC2 pilus-associated proteins in Kingella kingae pathogenicity | 000 | 1 | NIH | 2/17/2026 | $833,612 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08DK146197 | Elucidating the role of interleukin-22 in Hirschsprung Associated enterocolitis pathogenesis | 000 | 1 | NIH | 1/14/2026 | $159,288 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HG014500 | 3D Chromatin architectural dynamics at ultra-high resolution | 000 | 1 | NIH | 1/30/2026 | $863,248 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI187222 | Cul5 dampens cytokine sensing in Type II lymphocytes to prevent allergic airways remodeling | 000 | 1 | NIH | 2/4/2026 | $670,017 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08AI193172 | From inhibitors to enzymatic deficiencies: exploring alterations in erythrocyte glycolysis as an antimalarial strategy. | 000 | 2 | NIH | 6/30/2026 | $187,056 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08HL177281 | Dysregulation of transcription factors and chromatin architecture in Trisomy 21 hematopoietic disorders | 000 | 2 | NIH | 6/30/2026 | $158,976 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HD117422 | Pediatric Acute Respiratory distress syndrome MAnagement (PARMA) | 000 | 2 | NIH | 4/17/2026 | $738,333 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AR083245 | FGFR3 Activities in the Control of Skeletal Growth | 001 | 3 | NIH | 5/14/2026 | $35,046 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AR083245 | FGFR3 Activities in the Control of Skeletal Growth | 000 | 3 | NIH | 3/26/2026 | $630,824 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL179221 | Proteolytic Regulation of Factor VIII Before and After Activation | 000 | 2 | NIH | 6/23/2026 | $646,626 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA273328 | Re-Engaging AYA Survivors in Cancer-Related Healthcare (REACH): A Sequential Multiple Assignment Randomized Trial (SMART) | 000 | 4 | NIH | 3/30/2026 | $715,901 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AR061758 | Pathogenic Mechanisms in Hereditary Multiple Exostoses Syndrome | 001 | 15 | NIH | 5/14/2026 | $19,360 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AR061758 | Pathogenic Mechanisms in Hereditary Multiple Exostoses Syndrome | 000 | 15 | NIH | 3/31/2026 | $348,480 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HD114705 | Comprehensive identification and functional study of Esrp-regulated isoforms during epithelial-mesenchymal transition. | 000 | 2 | NIH | 2/26/2026 | $756,436 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | DP1DA063517 | Lifespan effects of prenatal and perinatal opioid exposure on the brain's metabolic-epigenetic axis | 000 | 2 | NIH | 6/3/2026 | $534,000 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | P01CA217959 | Discovering and Exploiting Mechanisms of Neuroblastoma Therapy Resistance | 000 | 8 | NIH | 4/27/2026 | $2,450,350 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA258524 | Tracking Peripheral T-Cell Repertoire Changes for Preoperative and Early Ovarian Cancer Diagnosis | 001 | 6 | NIH | 4/16/2026 | $83,785 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA258524 | Tracking Peripheral T-Cell Repertoire Changes for Preoperative and Early Ovarian Cancer Diagnosis | 000 | 6 | NIH | 1/16/2026 | $754,071 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA271523 | Novel Regulation of Oncogenic NRAS Signaling in Myeloid Malignancies | 000 | 5 | NIH | 3/4/2026 | $547,313 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K23HD119271 | Transplacental Antibiotic Exposures in Newborn Infants | 000 | 2 | NIH | 7/1/2026 | $159,976 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | DP2AI192737 | Decoding multidrug-resistant pathogen dynamics for clinically-relevant wastewater surveillance | 000 | 2 | NIH | 7/7/2026 | $534,000 |
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