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 | Issue Date FY: 2026 ( Subtotal = $63,474,512 ) (Continued on the next page) |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI187222 | Cul5 dampens cytokine sensing in Type II lymphocytes to prevent allergic airways remodeling | 000 | 1 | NIH | 2/4/2026 | $670,017 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI187202 | Chronic STAT3 signaling in STAT3 GOF causes CD8 T cell dysfunction via CD39 upregulation | 000 | 2 | NIH | 12/31/2025 | $709,449 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI180250 | Defining the four major routes of MHC class II antigen processing and presentation with influenza antigens | 000 | 3 | NIH | 5/7/2026 | $598,313 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI187335 | Manipulation of the DNA damage response and the proteome on viral genomes during Herpes Simplex Virus (HSV) infection | 000 | 2 | NIH | 12/1/2025 | $671,993 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI182049 | The B22 family of orthopoxvirus virulence factors: Investigating structure/function of these potent, multifaceted immunoevasins | 000 | 3 | NIH | 1/1/2026 | $742,230 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI184976 | Genetic determinates of SPI1 expression and activity in human germinal center B cells | 000 | 2 | NIH | 1/26/2026 | $801,574 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI181999 | Cul5 regulates lung ILC2 cells during helminth infection | 000 | 2 | NIH | 12/1/2025 | $674,760 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI172841 | Pathogenicity of the emerging pathogen Kingella kingae | 000 | 4 | NIH | 11/28/2025 | $445,000 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI103280 | MEP pathway resistance in Plasmodium falciparum | 000 | 14 | NIH | 4/2/2026 | $452,189 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AG077911 | Illuminating adipo-osteoprogenitors in the bone marrow | 001 | 4 | NIH | 2/24/2026 | $46,186 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AG077911 | Illuminating adipo-osteoprogenitors in the bone marrow | 000 | 4 | NIH | 1/16/2026 | $415,678 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R21AI182619 | Potent Signal 1 as a noncanonical Signal 3: antigen location, and peptide:MHCII complex density and half-life as drivers of CD4+ T cell differentiation | 000 | 2 | NIH | 12/10/2025 | $222,500 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R03CA293992 | Long-read, single-cell RNA sequencing of high-risk neuroblastoma samples | 001 | 2 | NIH | 4/17/2026 | $17,800 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R03CA293992 | Long-read, single-cell RNA sequencing of high-risk neuroblastoma samples | 000 | 2 | NIH | 12/23/2025 | $160,200 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R03DK147724 | Control of hemoglobin expression by the chromatin remodeler CHD7 | 000 | 1 | NIH | 5/7/2026 | $133,500 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS124640 | p38 MAPK activation as a therapeutic target for Friedreich ataxia | 000 | 5 | NIH | 4/27/2026 | $556,692 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS126469 | Eye as a Window into Brain Health in Pediatric Hydrocephalus | 000 | 4 | NIH | 4/27/2026 | $678,495 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS126541 | Glial metabolic status regulates axon regeneration in the central nervous system | 000 | 4 | NIH | 4/7/2026 | $559,992 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS137604 | A developmental mechanism of temperature-sensitive seizures towards therapeutic manipulation | 001 | 2 | NIH | 4/21/2026 | $57,495 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS137604 | A developmental mechanism of temperature-sensitive seizures towards therapeutic manipulation | 000 | 2 | NIH | 1/31/2026 | $517,460 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS127830 | Subgroup delineation in genetic epilepsies and developmental brain disorders | 000 | 4 | NIH | 4/7/2026 | $691,483 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS131512 | A computational phenotyping approach to characterize neurogenetic disorders | 000 | 4 | NIH | 4/7/2026 | $688,207 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01MH138428 | Intergenerational transmission of threat sensitivity as an risk marker for psychopathology in young children | 000 | 2 | NIH | 12/5/2025 | $593,833 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS110869 | Interneuron axonopathy underlies circuit dysfunction in a mouse model of Dravet syndrome | 000 | 7 | NIH | 2/24/2026 | $674,970 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS122887 | Mechanistically-oriented therapy for a progressive myoclonus epilepsy | 000 | 5 | NIH | 4/8/2026 | $501,794 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS120099 | INJURY-INDUCED SPATIAL MEMORY IMPAIRMENTS ARE LINKED TO UNCOORDINATED HIPPOCAMPAL NEURONAL FIRING | 001 | 5 | NIH | 2/28/2026 | $44,000 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS120099 | INJURY-INDUCED SPATIAL MEMORY IMPAIRMENTS ARE LINKED TO UNCOORDINATED HIPPOCAMPAL NEURONAL FIRING | 000 | 5 | NIH | 12/16/2025 | $396,000 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS082046 | Normal and Pathological Function of the Dentate Gyrus | 000 | 14 | NIH | 3/31/2026 | $568,054 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01MH136706 | Linking mitochondrial and synaptic weakness to schizophrenia | 000 | 3 | NIH | 1/21/2026 | $649,499 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01MH133838 | A longitudinal study identifying psychological and service delivery targets to improve daily living skills and quality of life outcomes among autistic youth exiting high school | 000 | 4 | NIH | 4/17/2026 | $791,853 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01MH134965 | 2/2 - Neurodevelopmental Trajectories in 22q11.2 Deletion Syndrome in Adolescence and Young Adulthood | 000 | 3 | NIH | 1/21/2026 | $484,313 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HS029500 | Implementing vancomycin-sparing regimens in preterm infants | 000 | 3 | AHRQ | 4/17/2026 | $488,937 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HS029188 | Smart checklist implementation for pediatric tracheal intubations in the ICU- multicenter study: SMART PICU | 000 | 4 | AHRQ | 4/27/2026 | $380,997 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL177971 | Lymphatic Dysfunction and Development of Post-Transplant Obliterative Bronchiolitis | 001 | 2 | NIH | 3/13/2026 | $21,920 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL177971 | Lymphatic Dysfunction and Development of Post-Transplant Obliterative Bronchiolitis | 000 | 2 | NIH | 1/30/2026 | $694,129 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL166217 | Determining the genetic and social determinants of heart failure and mortality in patients with congenital heart disease (DEFINE) | 001 | 4 | NIH | 4/6/2026 | $741,290 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL164536 | Decellularized cartilage and progenitor cells for laryngotracheal reconstruction | 001 | 2 | NIH | 3/25/2026 | $21,900 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL164536 | Decellularized cartilage and progenitor cells for laryngotracheal reconstruction | 000 | 2 | NIH | 2/18/2026 | $693,478 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL162715 | Impact of Obesity on Lung Macrophage Metabolism and Inflammation | 000 | 4 | NIH | 2/9/2026 | $549,173 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL162715 | Impact of Obesity on Lung Macrophage Metabolism and Inflammation | 001 | 4 | NIH | 3/25/2026 | $17,342 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HD116782 | Reducing Disparities in Access to High-level Neonatal Intensive Care and Neonatal Outcomes | 002 | 2 | NIH | 4/15/2026 | $71,691 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HD114622 | OPTImal VENTilation to Improve Pediatric Cardiac Arrest Outcomes | 001 | 2 | NIH | 4/6/2026 | $79,143 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HD116782 | Reducing Disparities in Access to High-level Neonatal Intensive Care and Neonatal Outcomes | 001 | 2 | NIH | 3/27/2026 | $0 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HD114622 | OPTImal VENTilation to Improve Pediatric Cardiac Arrest Outcomes | 000 | 2 | NIH | 1/15/2026 | $712,279 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HD117422 | Pediatric Acute Respiratory distress syndrome MAnagement (PARMA) | 000 | 2 | NIH | 4/17/2026 | $738,333 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HD116782 | Reducing Disparities in Access to High-level Neonatal Intensive Care and Neonatal Outcomes | 000 | 2 | NIH | 1/23/2026 | $645,225 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HD114705 | Comprehensive identification and functional study of Esrp-regulated isoforms during epithelial-mesenchymal transition. | 000 | 2 | NIH | 2/26/2026 | $756,436 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HG014500 | 3D Chromatin architectural dynamics at ultra-high resolution | 000 | 1 | NIH | 1/30/2026 | $863,248 |
| | 2026 | 2026 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HG013355 | Utilizing long-read sequencing to resolve inconclusive diagnoses and uncertainty in genetic testing | 000 | 3 | NIH | 2/26/2026 | $445,000 |
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