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 | Issue Date FY: 2025 ( Subtotal = $203,436,923 ) (Continued on the next page) |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U01DK066174 | Chronic Kidney Disease in Children (CKiD) | 002 | 24 | NIH | 7/30/2025 | $175,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U01DK066174 | Chronic Kidney Disease in Children (CKiD) | 002 | 24 | NIH | 7/30/2025 | $863,229 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U01DK066174 | Chronic Kidney Disease in Children (CKiD) | 002 | 24 | NIH | 7/30/2025 | $300,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DK134717 | Vitamin D control of calorie allocation to muscle | 000 | 3 | NIH | 2/17/2025 | $458,947 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA193776 | Improving risk allocation and developing novel therapies for children with T-ALL and T-LL | 001 | 8 | NIH | 5/22/2025 | $73,791 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA193776 | Improving risk allocation and developing novel therapies for children with T-ALL and T-LL | 000 | 8 | NIH | 2/28/2025 | $664,135 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AI185544 | High Resolution, Whole Genome Tracking of Pathogen Transmission and Infection in the Neonatal ICU (NICU) | 000 | 1 | NIH | 7/17/2025 | $881,303 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | UM454988 | Autism Research Consortium | 01 | 1 | HRSA | 9/3/2025 | $0 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | UM454988 | Autism Research Consortium | 00 | 1 | HRSA | 7/30/2025 | $1,059,242 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS131512 | A computational phenotyping approach to characterize neurogenetic disorders | 001 | 3 | NIH | 8/5/2025 | $70,222 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01NS131512 | A computational phenotyping approach to characterize neurogenetic disorders | 000 | 3 | NIH | 3/11/2025 | $631,987 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U01DK135002 | Assessing Diabetes Risk Origins in Teens (ADROIT) | 000 | 3 | NIH | 2/14/2025 | $749,173 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U19NS132301 | Guide RNA manufacturing capabilities for platform in vivo base editing therapies for metabolic liver diseases | 003 | 3 | NIH | 8/29/2025 | $0 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U19NS132301 | Guide RNA manufacturing capabilities for platform in vivo base editing therapies for metabolic liver diseases | 002 | 3 | NIH | 8/12/2025 | $1,000,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U19NS132301 | Guide RNA manufacturing capabilities for platform in vivo base editing therapies for metabolic liver diseases | 001 | 3 | NIH | 8/8/2025 | $5,059,052 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U19NS132301 | Guide RNA manufacturing capabilities for platform in vivo base editing therapies for metabolic liver diseases | 000 | 2 | NIH | 5/6/2025 | $29,667 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U24NS131172 | GLIA-CTN Genomic Expert Curation Panel | 000 | 3 | NIH | 6/27/2025 | $359,546 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DK138634 | The role of CD73 in esophageal epithelial homeostasis | 000 | 2 | NIH | 7/16/2025 | $728,143 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U01DA055365 | 3/24 Healthy Brain and Child Development National Consortium | 001 | 5 | NIH | 9/5/2025 | $1,783,874 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U01DA055365 | 3/24 Healthy Brain and Child Development National Consortium | 001 | 5 | NIH | 9/5/2025 | -$1,783,874 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U01DA055365 | 3/24 Healthy Brain and Child Development National Consortium | 000 | 5 | NIH | 7/14/2025 | $1,783,874 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DE032332 | Functional analysis of ESRP1/2 and CTNND1 gene variants in orofacial cleft | 001 | 3 | NIH | 5/7/2025 | $61,330 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DE032332 | Functional analysis of ESRP1/2 and CTNND1 gene variants in orofacial cleft | 000 | 3 | NIH | 1/17/2025 | $551,976 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01FD008225 | PKDNet - ARPKD Learning Network | 000 | 2 | FDA | 8/18/2025 | $400,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R00HL177827 | Determining genetic mechanisms that drive in vitro hematopoiesis | 000 | 1 | NIH | 7/15/2025 | $445,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | DP1DA063517 | Lifespan effects of prenatal and perinatal opioid exposure on the brain's metabolic-epigenetic axis | 000 | 1 | NIH | 8/21/2025 | $534,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA248501 | Mechanistic biomarkers to enable Bcl2 inhibitor therapies for neuroblastoma | 001 | 5 | NIH | 5/22/2025 | $39,500 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AR061758 | Pathogenic Mechanisms in Hereditary Multiple Exostoses Syndrome | 001 | 14 | NIH | 5/19/2025 | $27,104 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01CA248501 | Mechanistic biomarkers to enable Bcl2 inhibitor therapies for neuroblastoma | 000 | 5 | NIH | 2/13/2025 | $355,506 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01AR061758 | Pathogenic Mechanisms in Hereditary Multiple Exostoses Syndrome | 000 | 14 | NIH | 3/14/2025 | $348,480 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HD114705 | Comprehensive identification and functional study of Esrp-regulated isoforms during epithelial-mesenchymal transition. | 000 | 1 | NIH | 3/12/2025 | $763,886 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U54DE035976 | Advancing Craniosynostosis Treatment (ACT)Rare Diseases Consortium | 001 | 1 | NIH | 8/29/2025 | -$530,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U54DE035976 | Advancing Craniosynostosis Treatment (ACT)Rare Diseases Consortium | 000 | 1 | NIH | 8/19/2025 | $530,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U54DE035976 | Advancing Craniosynostosis Treatment (ACT)Rare Diseases Consortium | 000 | 1 | NIH | 8/19/2025 | $800,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U54DE035976 | Advancing Craniosynostosis Treatment (ACT)Rare Diseases Consortium | 000 | 1 | NIH | 8/19/2025 | $200,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R21HD120719 | Natural History Study and Identification of Patient-Centric Clinical Outcome Assessments in TUBB4A-LD (NIH R21) | 000 | 1 | NIH | 8/29/2025 | $415,245 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U54DE035976 | Advancing Craniosynostosis Treatment (ACT)Rare Diseases Consortium | 001 | 1 | NIH | 8/29/2025 | $530,000 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HD117422 | Pediatric Acute Respiratory distress syndrome MAnagement (PARMA) | 000 | 1 | NIH | 8/15/2025 | $767,069 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01DK142682 | Autophagy, injury, and plasticity in the intestinal regenerative process | 000 | 1 | NIH | 9/8/2025 | $836,942 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | RF1MH129594 | Developing electrophysiological markers for clinical trials in autistic adults | 000 | 4 | NIH | 9/4/2025 | $1,492,966 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R50CA305079 | Rare Tumor Clinical Research Specialist | 000 | 1 | NIH | 9/8/2025 | $197,518 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HD117777 | Medicaid Enrollment and Outcomes Over the Reproductive Lifecourse | 000 | 1 | NIH | 9/10/2025 | $730,191 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL180442 | Lung Injury in ONcologic Stem cell transplants (LIONS) | 000 | 1 | NIH | 9/10/2025 | $879,567 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U54HL185006 | ARDVARC-Advancing Rare Disorders: Vascular mAlformation Research Network with CaNVAS | 000 | 1 | NIH | 9/8/2025 | $968,769 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HD119165 | Neural markers of late language emergence in preschool children born very and extremely preterm | 000 | 1 | NIH | 9/10/2025 | $2,375,939 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R21TR006299 | Patient-Centric Clinical Outcome Measures for Multiple Sulfatase Deficiency (MSD) | 000 | 1 | NIH | 9/3/2025 | $489,500 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | U54HL185006 | ARDVARC-Advancing Rare Disorders: Vascular mAlformation Research Network with CaNVAS | 000 | 1 | NIH | 9/8/2025 | $890,459 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | K08DK141964 | Elucidating Effector CD8 T-Cell – Kupffer Cell InterferonGamma Interaction in Pediatric Activated T-cell Acute Liver Failure | 000 | 1 | NIH | 9/11/2025 | $159,408 |
| | 2025 | 2025 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 3401 CIVIC CENTER BLVD | PHILADELPHIA | PA | 19104-4319 | PHILADELPHIA | USA | R01HL160748 | Preserving Genome Integrity In AAV-Mediated Gene Therapy | 001 | 4 | NIH | 8/14/2025 | $64,523 |
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