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The NIGMS Human Genetic Cell Repository

Award Number: U42GM115336
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 03/15/2015
PERIOD OF PERFORMANCE END DATE: 02/28/2025

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The NIGMS Human Genetic Cell Repository - The NIGMS Human Genetic Cell Repository U42 Application FOA No.: RFA-GM-19-002 Project Summary/Abstract Coriell Institute for Medical Research (Coriell) proposes to maintain and expand the NIGMS Human Genetic Cell Repository (HGCR). The NIGMS HGCR, established in 1972 at Coriell by the National Institute of General Medical Sciences (NIGMS), provides a readily accessible, centralized resource for biospecimens from individuals with inherited disorders, chromosomal abnormalities, apparently healthy individuals, and individuals of diverse geographic origins for use in biomedical research. The primary goal of the NIGMS HGCR is to stimulate and facilitate biomedical research, teaching, and the diagnosis and prevention of human genetic diseases by establishing and maintaining a repository of high quality, uncontaminated, well characterized, and clinically well-documented cell lines and DNA and making these resources available to investigators throughout the U.S. and abroad. The NIGMS HGCR mission is in line with the NIGMS mission, which is “to support research that increases understanding of life processes and lays the foundation for advances in disease diagnosis, treatment and prevention”. The NIGMS HGCR’s activities, all governed by high standards of quality, will include (1) collection, establishment, characterization, maintenance, and distribution of cell lines, (2) preparation, storage and distribution of DNA from cell lines, (3) the development and offering of special genetic services and biomaterials in response to customer requests, (4) maintenance of a comprehensive database and online catalog, and (5) publicizing the NIGMS HGCR’s collections. The NIGMS HGCR will maintain, grow and distribute the current collection of approximately 11,800 unique cell lines, 6,400 DNA samples, and 54 human iPSC lines in its online catalog, as well as newly acquired resources. The NIGMS HGCR will continue to create human induced pluripotent stem cell (iPSC) lines at Coriell by reprogramming certain NIGMS HGCR cell lines. Additionally, Coriell is committed to integrating state-of-the-art technologies into its activities and will continue to offer a wide range of cutting edge services that enhance the utility of the HGCR collection to the genetic research community.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $1,622,641 )
2024	2024	CORIELL INSTITUTE FOR MEDICAL RESEARCH, INC.	403 HADDON AVE	CAMDEN	NJ	08103	CAMDEN	USA	Biomedical Research and Research Training	000	10	2/27/2024	NON-COMPETING CONTINUATION	$1,460,377
2024	2024	CORIELL INSTITUTE FOR MEDICAL RESEARCH, INC.	403 HADDON AVE	CAMDEN	NJ	08103	CAMDEN	USA	Biomedical Research and Research Training	001	10	6/19/2024	NON-COMPETING CONTINUATION	$162,264
														Subtotal = $1,622,641

Issue Date FY: 2023 ( Subtotal = $1,825,714 )
2023	2023	CORIELL INSTITUTE FOR MEDICAL RESEARCH INC	403 HADDON AVE	CAMDEN	NJ	08103	CAMDEN	USA	Biomedical Research and Research Training	000	9	2/14/2023	NON-COMPETING CONTINUATION	$1,825,714
														Subtotal = $1,825,714

Issue Date FY: 2022 ( Subtotal = $1,825,470 )
2022	2022	CORIELL INSTITUTE FOR MEDICAL RESEARCH, INC.	403 HADDON AVE	CAMDEN	NJ	08103	CAMDEN	USA	Biomedical Research and Research Training	001	8	5/23/2022	NON-COMPETING CONTINUATION	$182,550
2022	2022	CORIELL INSTITUTE FOR MEDICAL RESEARCH, INC.	403 HADDON AVE	CAMDEN	NJ	08103	CAMDEN	USA	Biomedical Research and Research Training	000	8	2/14/2022	NON-COMPETING CONTINUATION	$1,642,920
														Subtotal = $1,825,470

Issue Date FY: 2021 ( Subtotal = $2,000,000 )
2021	2021	CORIELL INSTITUTE FOR MEDICAL RESEARCH, INC.	403 HADDON AVE	CAMDEN	NJ	08103	CAMDEN	USA	Biomedical Research and Research Training	001	7	3/1/2021	NON-COMPETING CONTINUATION	$2,000,000
2021	2020	CORIELL INSTITUTE FOR MEDICAL RESEARCH, INC.	403 HADDON AVE	CAMDEN	NJ	08103	CAMDEN	USA	Biomedical Research and Research Training	000	6	11/18/2020	COMPETING CONTINUATION	$0
														Subtotal = $2,000,000

Issue Date FY: 2020 ( Subtotal = $2,000,000 )
2020	2020	CORIELL INSTITUTE FOR MEDICAL RESEARCH, INC.	403 HADDON AVE	CAMDEN	NJ	08103	CAMDEN	USA	Biomedical Research and Research Training	000	6	3/30/2020	COMPETING CONTINUATION	$2,000,000
2020	2019	CORIELL INSTITUTE FOR MEDICAL RESEARCH, INC.	403 HADDON AVE	CAMDEN	NJ	08103	CAMDEN	USA	Biomedical Research and Research Training	001	5	9/6/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,000,000

Issue Date FY: 2019 ( Subtotal = $2,800,000 )
2019	2019	CORIELL INSTITUTE FOR MEDICAL RESEARCH, INC.	403 HADDON AVE	CAMDEN	NJ	08103	CAMDEN	USA	Biomedical Research and Research Training	001	5	2/27/2019	NON-COMPETING CONTINUATION	$2,800,000
2019	2018	CORIELL INSTITUTE FOR MEDICAL RESEARCH, INC.	403 HADDON AVE	CAMDEN	NJ	08103	CAMDEN	USA	Biomedical Research and Research Training	000	4	11/27/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,800,000

Issue Date FY: 2018 ( Subtotal = $2,800,000 )
2018	2018	CORIELL INSTITUTE FOR MEDICAL RESEARCH, INC.	403 HADDON AVE	CAMDEN	NJ	08103	CAMDEN	USA	Biomedical Research and Research Training	001	4	4/25/2018	NON-COMPETING CONTINUATION	$280,001
2018	2018	CORIELL INSTITUTE FOR MEDICAL RESEARCH, INC.	403 HADDON AVE	CAMDEN	NJ	08103	CAMDEN	USA	Biomedical Research and Research Training	000	4	2/22/2018	NON-COMPETING CONTINUATION	$2,519,999
														Subtotal = $2,800,000

Issue Date FY: 2017 ( Subtotal = $2,800,000 )
2017	2017	CORIELL INSTITUTE FOR MEDICAL RESEARCH, INC.	403 HADDON AVE	CAMDEN	NJ	08103	CAMDEN	USA	Biomedical Research and Research Training	001	3	7/26/2017	NON-COMPETING CONTINUATION	$280,001
2017	2017	CORIELL INSTITUTE FOR MEDICAL RESEARCH, INC.	403 HADDON AVE	CAMDEN	NJ	08103	CAMDEN	USA	Biomedical Research and Research Training	000	3	2/27/2017	NON-COMPETING CONTINUATION	$2,519,999
														Subtotal = $2,800,000

Issue Date FY: 2016 ( Subtotal = $2,800,000 )
2016	2016	CORIELL INSTITUTE FOR MEDICAL RESEARCH INC	403 HADDON AVENUE	CAMDEN	NJ	08103	CAMDEN	USA	Biomedical Research and Research Training	000	2	3/4/2016	NON-COMPETING CONTINUATION	$2,800,000
														Subtotal = $2,800,000

Issue Date FY: 2015 ( Subtotal = $2,800,000 )
2015	2015	CORIELL INSTITUTE FOR MEDICAL RESEARCH INC	403 HADDON AVENUE	CAMDEN	NJ	08103	CAMDEN	USA	Biomedical Research and Research Training	000	1	3/13/2015	NEW	$2,800,000
														Subtotal = $2,800,000

Grand Total All Awards = $23,273,825

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The NIGMS Human Genetic Cell Repository

Award Number: U42GM115336

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 03/15/2015

PERIOD OF PERFORMANCE END DATE: 02/28/2025

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