Monday, December 22, 2025 12/22/2025

Advancing Standardization of Neurophysiology Data Through Dissemination of NWB

Award Number: U24NS120057
ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 04/01/2021
PERIOD OF PERFORMANCE END DATE: 02/28/2027

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Advancing Standardization of Neurophysiology Data Through Dissemination of NWB - PROJECT SUMMARY Lack of standards for neurophysiology data and related metadata is the single greatest impediment to fully extracting return on investment from neurophysiology experiments. One of the greatest questions in science today is understanding how the brain works and gives rise to thoughts, memories, perception, and consciousness. To address this challenge, neurophysiologists within the NIH BRAIN initiative and around the world perform experiments that measure neuronal activity from different parts of the brain and relate that activity to sensation and behavior. A key component of the BRAIN Initiative is to support sharing of these rich datasets and extend their value by enabling reuse of data within and across labs. The goal of this proposal is to disseminate Neurodata Without Borders (NWB) neurophysiology technologies developed as part of the NIH BRAIN Initiative broadly to the neuroscience research community. NWB is an award-winning, community-driven data standard and software ecosystem for neurophysiology. To facilitate data sharing and reuse, the NWB format standardizes how neurophysiology data and associated metadata are stored, and the NWB software enables researchers to access and save data in the NWB format easily and efficiently. Several leading neuroscience labs and institutions now produce data in NWB; however, a substantial energy barrier remains for labs to standardize their data. To lower the barrier of adopting NWB, we propose a multifaceted plan to make NWB easier to use by focusing on the needs of 1) neuroscience researchers and laboratories by enhancing user training, support, and coverage of new technologies and 2) neuroscience tools and technologies by maintaining core NWB technologies and integrating with a wide array of powerful data tools and technologies. With NWB data as a target, scientists can access, manage, and share data using common protocols, while developers have a common format on top of which to build tools. By targeting these two areas simultaneously, we aim to reduce cost, time, and effort for analysis; improve quality, reliability, and accuracy of results; and enable scientists to access new scientific capabilities. Successful completion of the proposed work will enable broad dissemination of NWB to neuroscience labs and researchers and integration of NWB with neuroscience tools, providing the research community with an accessible data standard and software ecosystem that enhances utilization, sharing, quality, reliability, and analysis of neurophysiology data.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2025	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA	1 CYCLOTRON RD	BERKELEY	CA	94720	ALAMEDA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	5	12/19/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2025 ( Subtotal = $1,056,178 )
2025	2025	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA	1 CYCLOTRON RD	BERKELEY	CA	94720	ALAMEDA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	5	3/31/2025	NON-COMPETING CONTINUATION	$1,056,178
														Subtotal = $1,056,178

Issue Date FY: 2024 ( Subtotal = $1,056,178 )
2024	2024	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA	1 CYCLOTRON RD	BERKELEY	CA	94720	ALAMEDA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	4	2/8/2024	NON-COMPETING CONTINUATION	$1,056,178
														Subtotal = $1,056,178

Issue Date FY: 2023 ( Subtotal = $1,402,208 )
2023	2023	REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE	1 CYCLOTRON RD	BERKELEY	CA	94720	ALAMEDA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	3	1/24/2023	NON-COMPETING CONTINUATION	$1,173,518
2023	2023	REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE	1 CYCLOTRON RD	BERKELEY	CA	94720	ALAMEDA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	3	8/17/2023	SUPPLEMENT FOR EXPANSION	$228,690
														Subtotal = $1,402,208

Issue Date FY: 2022 ( Subtotal = $1,173,002 )
2022	2022	REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE	1 CYCLOTRON RD	BERKELEY	CA	94720	ALAMEDA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	2	3/24/2022	NON-COMPETING CONTINUATION	$117,289
2022	2022	REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE	1 CYCLOTRON RD	BERKELEY	CA	94720	ALAMEDA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	2	2/15/2022	NON-COMPETING CONTINUATION	$1,055,713
														Subtotal = $1,173,002

Issue Date FY: 2021 ( Subtotal = $1,183,839 )
2021	2021	REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE	1 CYCLOTRON RD	BERKELEY	CA	94720	ALAMEDA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	1	6/28/2021	NEW	$118,413
2021	2021	REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE	1 CYCLOTRON RD	BERKELEY	CA	94720	ALAMEDA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	1	3/17/2021	NEW	$1,065,426
														Subtotal = $1,183,839

Grand Total All Awards = $5,871,405

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Advancing Standardization of Neurophysiology Data Through Dissemination of NWB

Award Number: U24NS120057

ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 04/01/2021

PERIOD OF PERFORMANCE END DATE: 02/28/2027

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