Monday, June 30, 2025 6/30/2025

Michigan SIREN Collaborative

Award Number: U24NS100680
ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/15/2017
PERIOD OF PERFORMANCE END DATE: 01/31/2028

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Michigan SIREN Collaborative - The Michigan SIREN Collaborative (MI-SIREN) is organized around a strong network of research universities and hospitals with long-term successful collaborations. MI-SIREN includes 2 previous NETT hubs (Wayne State University (WSU) and Henry Ford Health Systems). MI-SIREN encompasses a hub and 8 primary spokes situated within 7 sizeable health care systems. MI-SIREN is affiliated with five major research universities, Wayne State University, Michigan State University, University of Michigan, University of Virginia and Oakland University. MI-SIREN accounted for over 940,000 ED annual visits in 2019 and 2020. MI-SIREN incorporates eight designated ST elevation myocardial infarction (STEM) centers, seven level 1 trauma centers, four Children’s hospitals, three certified burn centers, and three level 1 pediatric trauma centers. MI-SIREN has the capacity to provide the diverse population of critical patients required for SIREN. MI-SIREN incorporates innovative enrollment and retention practices like a three-tiered enrollment, designated duties, and shared employees which reduces errors and increases enrollment. MI-SIREN has tight collaboration with EMS divisions in metropolitan Detroit, Ann Arbor, Grand Rapids, and Charlottesville, Virginia and has performed multiple Exception From Informed Consent (EFIC) studies. MI-SIREN is the third highest enroller in the current SIREN Network with exceptional quality metrics. MI-SIREN provides access to nearly the entire population of Detroit, MI, approximately 680,000 with 82% African American, and 49.8% living below the poverty level. MI-SIREN will build upon our exemplary subject recruitment by leveraging shared resources, making strategic investment into spokes, and expanding capacity. MI-SIREN will support, engage, and train the next generation of diverse clinical scientists. MI-SIREN will encourage faculty to enrich SIREN leadership and actively pursue grant proposals utilizing the SIREN network. MI-SIREN offers a pipeline for SIREN grant submissions through our expert faculty. MI-SIREN has a proven record of engaged high quality performance of clinical trials.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $341,465 )
2025	2025	WAYNE STATE UNIVERSITY	5700 CASS AVE STE 4900	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	003	8	2/18/2025	NON-COMPETING CONTINUATION	$0
2025	2025	WAYNE STATE UNIVERSITY	5700 CASS AVE STE 4900	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	002	8	2/13/2025	NON-COMPETING CONTINUATION	$341,465
2025	2024	WAYNE STATE UNIVERSITY	5700 CASS AVE STE 4900	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	7	12/5/2024	NON-COMPETING CONTINUATION	$0
2025	2024	WAYNE STATE UNIVERSITY	5700 CASS AVE STE 4900	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	7	1/14/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $341,465

Issue Date FY: 2024 ( Subtotal = $351,850 )
2024	2024	WAYNE STATE UNIVERSITY	5700 CASS AVE STE 4900	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	005	7	5/7/2024	NON-COMPETING CONTINUATION	$25,392
2024	2024	WAYNE STATE UNIVERSITY	5700 CASS AVE STE 4900	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	004	7	1/30/2024	NON-COMPETING CONTINUATION	$326,458
2024	2023	WAYNE STATE UNIVERSITY	5700 CASS AVE STE 4900	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	002	6	12/28/2023	COMPETING CONTINUATION	$0
2024	2023	WAYNE STATE UNIVERSITY	5700 CASS AVE STE 4900	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	003	6	1/19/2024	COMPETING CONTINUATION	$0
2024	2023	WAYNE STATE UNIVERSITY	5700 CASS AVE STE 4900	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	6	12/12/2023	COMPETING CONTINUATION	$151
2024	2022	WAYNE STATE UNIVERSITY	5700 CASS AVE STE 4900	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	5	12/12/2023	SUPPLEMENT FOR EXPANSION	-$151
														Subtotal = $351,850

Issue Date FY: 2023 ( Subtotal = $376,231 )
2023	2023	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	6	2/1/2023	COMPETING CONTINUATION	$376,231
2023	2022	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	002	5	2/15/2023	SUPPLEMENT FOR EXPANSION	$0
2023	2021	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	5	1/20/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $376,231

Issue Date FY: 2022 ( Subtotal = $73,781 )
2022	2022	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	5	5/27/2022	SUPPLEMENT FOR EXPANSION	$73,781
2022	2020	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	4	11/22/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $73,781

Issue Date FY: 2021 ( Subtotal = $135,720 )
2021	2021	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	5	6/10/2021	NON-COMPETING CONTINUATION	$135,720
														Subtotal = $135,720

Issue Date FY: 2020 ( Subtotal = $139,567 )
2020	2020	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	002	4	6/17/2020	NON-COMPETING CONTINUATION	$139,567
2020	2019	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	3	5/20/2020	NON-COMPETING CONTINUATION	$0
2020	2019	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	3	6/15/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $139,567

Issue Date FY: 2019 ( Subtotal = $143,413 )
2019	2019	WAYNE STATE UNIVERSITY	5057 WOODWARD 13 FLOOR	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	002	3	8/28/2019	NON-COMPETING CONTINUATION	$0
2019	2019	WAYNE STATE UNIVERSITY	5057 WOODWARD 13 FLOOR	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	3	6/28/2019	NON-COMPETING CONTINUATION	$143,413
2019	2018	WAYNE STATE UNIVERSITY	5057 WOODWARD 13 FLOOR	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	2	10/29/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $143,413

Issue Date FY: 2018 ( Subtotal = $135,336 )
2018	2018	WAYNE STATE UNIVERSITY	5057 WOODWARD 13 FLOOR	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	2	5/30/2018	NON-COMPETING CONTINUATION	$135,336
														Subtotal = $135,336

Issue Date FY: 2017 ( Subtotal = $246,400 )
2017	2017	WAYNE STATE UNIVERSITY	5057 WOODWARD 13 FLOOR	DETROIT	MI	48202	WAYNE	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	1	7/6/2017	NEW	$246,400
														Subtotal = $246,400

Grand Total All Awards = $1,943,763

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Michigan SIREN Collaborative

Award Number: U24NS100680

ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/15/2017

PERIOD OF PERFORMANCE END DATE: 01/31/2028

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