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 | Issue Date FY: 2025 ( Subtotal = $35,841,836 ) (Continued on the next page) |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R21AI182688 | Regulation of Innate Immunity by the Hippo Kinases | 000 | 2 | NIH | 2/25/2025 | $185,671 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01AG081981 | Novel Early Retinal Imaging Biomarkers for Treating Later Spatial Memory Loss in Experimental Alzheimer's Disease | 003 | 3 | NIH | 6/24/2025 | $0 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01AG081981 | Novel Early Retinal Imaging Biomarkers for Treating Later Spatial Memory Loss in Experimental Alzheimer's Disease | 000 | 3 | NIH | 5/19/2025 | $977,580 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01AG081981 | Novel Early Retinal Imaging Biomarkers for Treating Later Spatial Memory Loss in Experimental Alzheimer's Disease | 001 | 3 | NIH | 6/17/2025 | $86,896 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01EY035231 | Airborne Particulates, Corneal Oxidative Stress and Infection | 000 | 3 | NIH | 6/4/2025 | $394,376 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R03DK140261 | High salt-dependent regulation of the Na+/K+/2Cl- co-transporter (NKCC2) ubiquitination by E3-ubiquitin ligases in Thick Ascending Limb | 000 | 1 | NIH | 6/11/2025 | $115,500 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R35GM150892 | Subcellular mechanisms coupling lipid synthesis and methionine metabolism | 000 | 3 | NIH | 4/8/2025 | $370,480 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01AG079097 | Profiling Psychosocial Dementia Caregiving Networks: The Impact of Dementia Care Networks on Care Outcomes of Medicare Enrollee Persons Living with Dementia | 000 | 4 | NIH | 5/8/2025 | $405,147 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01CA269607 | Targeted drug delivery system to overcome blood-brain barrier and therapeutic resistance to current standard of care in Glioblastoma | 000 | 4 | NIH | 6/24/2025 | $511,948 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R61MH137105 | Cannabidiol-enhanced cognitive behavioral therapy for generalized anxiety disorder | 000 | 1 | NIH | 5/19/2025 | $1,715,387 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R21AI180183 | The Role of UNG2 Degradation in Antibody Maturation | 000 | 2 | NIH | 4/18/2025 | $228,200 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | K01AG076740 | Maximizing the Scalability of the Chronic Disease Self-Management Program (CDSMP) Among Older Adults in State Correctional Settings | 000 | 3 | NIH | 3/24/2025 | $118,806 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01EY034964 | The Warburg Effect and Diabetic Retinopathy | 000 | 3 | NIH | 4/21/2025 | $385,000 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01ES033171 | Benzene exposure promotes neuroinflammation and metabolic dysregulation | 000 | 4 | NIH | 1/16/2025 | $359,423 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01DK126743 | Molecular and cellular analysis of the ABHD5/PNPLA3 metabolon in lipid homeostasis | 000 | 5 | NIH | 6/23/2025 | $476,166 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01GM146803 | A new paradigm of general transcription factor TFIIB functionality in termination and promoter directionality | 000 | 4 | NIH | 5/19/2025 | $307,648 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R35GM142637 | Spatiotemporal tools to interrogate O-GlcNAc functions in cellular signaling | 000 | 5 | NIH | 4/30/2025 | $360,742 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01EY033516 | Diabetic Retinopathy, Mitochondria Damage and Long Non-coding RNAs | 000 | 4 | NIH | 6/4/2025 | $346,500 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01DK129681 | Infusion device optimization by addressing root causes of the inflammatory response | 001 | 4 | NIH | 6/13/2025 | $51,063 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01DK129681 | Infusion device optimization by addressing root causes of the inflammatory response | 000 | 4 | NIH | 4/9/2025 | $459,580 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01ES036178 | Environmental ethoxylated surfactants and metabolic health dysregulation in zebrafish | 000 | 1 | NIH | 6/2/2025 | $756,318 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01DA052386 | The effects of gestational opioid exposure on the maternal brain, behavior and microbiome | 000 | 4 | NIH | 6/6/2025 | $333,094 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01HL163844 | Impact of Dietary Fructose and High Salt Diet on Neurocardiovascular and Renal Function | 000 | 4 | NIH | 3/31/2025 | $563,476 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01EB035631 | Enabling systemic delivery of europium-containing contrast agents for magnetic resonance imaging | 000 | 1 | NIH | 5/7/2025 | $578,863 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01AI169505 | Synthesis and Evaluation of Carbohydrate Vaccine Adjuvants | 001 | 4 | NIH | 6/2/2025 | $1,271,476 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | D4045693 | Graduate Psychology Education Programs | 00 | 4 | HRSA | 6/11/2025 | $449,254 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01HL153377 | Stress and Cardiovascular Risk Among Urban African American Adults: A Multilevel, Mixed Methods Approach:Supplement | 002 | 4 | NIH | 6/6/2025 | $0 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01HL153377 | Stress and Cardiovascular Risk Among Urban African American Adults: A Multilevel, Mixed Methods Approach:Supplement | 001 | 4 | NIH | 12/15/2024 | $22,821 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | T32GM139807 | IMSD at Wayne State University | 001 | 5 | NIH | 4/24/2025 | $0 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | T32GM139807 | IMSD at Wayne State University | 000 | 5 | NIH | 1/22/2025 | $341,418 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R00CA252152 | Does obesity influence protein quality control in endometrial cancer? | 001 | 5 | NIH | 5/22/2025 | $24,900 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R00CA252152 | Does obesity influence protein quality control in endometrial cancer? | 000 | 5 | NIH | 3/14/2025 | $224,100 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01HD105944 | Intraflagellar transport (IFT) and sperm formation | 000 | 4 | NIH | 2/12/2025 | $478,365 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01ES034410 | Interaction between Genome and Heavy Metals in Nonalcoholic Fatty Liver Disease | 000 | 3 | NIH | 3/19/2025 | $586,862 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01EY026964 | Targeting NAD metabolism to ameliorate bacterial endophthalmitis | 000 | 9 | NIH | 3/17/2025 | $325,703 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01DK090313 | A novel CREBH-derived hepatokine regulates triglyceride metabolism | 000 | 13 | NIH | 2/20/2025 | $365,780 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01DK132065 | Mitochondrial NAD kinase: function and mechanism in metabolism | 001 | 4 | NIH | 6/12/2025 | $37,595 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01DK132065 | Mitochondrial NAD kinase: function and mechanism in metabolism | 000 | 4 | NIH | 3/5/2025 | $338,358 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | F30GM149139 | Epigenetic Regulation of Langerhans Cell Histiocytosis Pathophysiology and Microenvironment by HDAC3 | 001 | 2 | NIH | 5/22/2025 | $376 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | F30GM149139 | Epigenetic Regulation of Langerhans Cell Histiocytosis Pathophysiology and Microenvironment by HDAC3 | 000 | 2 | NIH | 3/5/2025 | $39,246 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | UG1CA233163 | National Clinical Trials Network (NCTN) - Lead Academic Participating Site (LAPS) | 000 | 6 | NIH | 3/13/2025 | $303,263 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01HD111146 | Impact of benzene-induced MIA on fetal T cell development | 000 | 3 | NIH | 2/13/2025 | $335,766 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01CA251676 | Dual function of HSP70 in cytoprotection of tumor cells and generation of permissive microenvironment | 002 | 6 | NIH | 4/25/2025 | $317,049 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01CA251676 | Dual function of HSP70 in cytoprotection of tumor cells and generation of permissive microenvironment | 004 | 6 | NIH | 6/9/2025 | $35,226 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R21EY037082 | Differential impact of acute and chronic opioids on ocular innate immunity and infections | 000 | 1 | NIH | 1/27/2025 | $192,500 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01ES035692 | PFAS increases susceptibility to infection-mediated PTB | 000 | 2 | NIH | 6/4/2025 | $584,355 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01NS086778 | MOLECULAR MECHANISMS OF NEUROPROTECTION IN POLYGLUTAMINE-DEPENDENT DEGENERATION | 002 | 11 | NIH | 11/13/2024 | $428,150 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01NS086778 | MOLECULAR MECHANISMS OF NEUROPROTECTION IN POLYGLUTAMINE-DEPENDENT DEGENERATION | 003 | 11 | NIH | 11/14/2024 | $130,838 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01AG089566 | Local protein synthesis in tau pathology neurodegeneration | 000 | 2 | NIH | 5/27/2025 | $377,300 |
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