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 | Issue Date FY: 2025 ( Subtotal = $35,841,836 ) (Continued on the next page) |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01EY027381 | Ferroptosis in bacterial endophthalmitis: Mechanisms and Therapeutic targeting | 000 | 7 | NIH | 5/29/2025 | $453,470 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01NS094570 | Investigating the source and the action behind shunt obstruction in the treatment of pediatric hydrocephalus | 003 | 8 | NIH | 5/22/2025 | $525,636 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R21AG083760 | Redirected CaMKII for restoring deficits in Alzheimer's disease models | 000 | 2 | NIH | 4/28/2025 | $182,915 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | F30CA291094 | Investigating the MAIT cell- Microbiome Relationship in Pancreatic Cancer Liver Metastasis | 001 | 2 | NIH | 5/29/2025 | $564 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01MD018583 | Family mHealth Intervention to Improve Health Outcomes in Black Youth with Type 1 Diabetes: A Multi-Center Randomized Controlled Trial | 000 | 3 | NIH | 1/1/2025 | $530,699 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01CA250469 | Therapeutic Targeting Mitochondrial C1 Metabolism | 001 | 5 | NIH | 6/12/2025 | $61,444 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01CA250469 | Therapeutic Targeting Mitochondrial C1 Metabolism | 000 | 5 | NIH | 12/13/2024 | $552,994 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | P30CA022453 | CANCER CENTER SUPPORT GRANT | 000 | 43 | NIH | 12/3/2024 | $2,368,190 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01HL161233 | Contribution of neuroplasticity in the rostral ventrolateral medulla to physical inactivity-related cardiovascular disease | 000 | 4 | NIH | 11/13/2024 | $556,551 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01EY035785 | Role of Programmed Cell Death Pathways in Bacterial Keratitis | 000 | 2 | NIH | 4/11/2025 | $433,576 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R35GM150570 | Mechanisms of polarized protein sorting in AP-1B-deficient epithelia | 000 | 3 | NIH | 6/4/2025 | $385,000 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01DC020299 | Targeting nitrative stress for treatment of cisplatin ototoxicity | 001 | 3 | NIH | 5/1/2025 | $36,525 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01DC020299 | Targeting nitrative stress for treatment of cisplatin ototoxicity | 000 | 3 | NIH | 11/18/2024 | $328,726 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01HD110462 | Sperm mitochondrial biomarkers and male reproductive health | 001 | 2 | NIH | 4/7/2025 | $0 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01HD110462 | Sperm mitochondrial biomarkers and male reproductive health | 000 | 2 | NIH | 1/15/2025 | $583,177 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01NS134695 | Non-invasive infrared light therapy and medical device to treat spinal cord injury | 000 | 2 | NIH | 6/5/2025 | $561,974 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01ES022606 | Expression, Regulation and Function of the SULT1C Carcinogen-Activating Enzymes | 000 | 10 | NIH | 12/17/2024 | $610,104 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R35GM149271 | Regulation of inositol biosynthesis and consequences of inositol depletion | 001 | 3 | NIH | 1/16/2025 | $333,995 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01NS064033 | Functional brain mapping in pediatric neurosurgery | 000 | 14 | NIH | 4/25/2025 | $474,090 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | T32GM142519 | Chemistry Biology Interface Training Program at Wayne State University | 000 | 5 | NIH | 6/11/2025 | $292,380 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01DK131114 | Regulation of NKCC2 and renal NaCl transport by protein-protein interactions | 000 | 3 | NIH | 12/23/2024 | $484,984 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R21AI182688 | Regulation of Innate Immunity by the Hippo Kinases | 000 | 2 | NIH | 2/25/2025 | $185,671 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01AG081981 | Novel Early Retinal Imaging Biomarkers for Treating Later Spatial Memory Loss in Experimental Alzheimer's Disease | 003 | 3 | NIH | 6/24/2025 | $0 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01AG081981 | Novel Early Retinal Imaging Biomarkers for Treating Later Spatial Memory Loss in Experimental Alzheimer's Disease | 000 | 3 | NIH | 5/19/2025 | $977,580 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01AG081981 | Novel Early Retinal Imaging Biomarkers for Treating Later Spatial Memory Loss in Experimental Alzheimer's Disease | 001 | 3 | NIH | 6/17/2025 | $86,896 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01EY035231 | Airborne Particulates, Corneal Oxidative Stress and Infection | 000 | 3 | NIH | 6/4/2025 | $394,376 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R03DK140261 | High salt-dependent regulation of the Na+/K+/2Cl- co-transporter (NKCC2) ubiquitination by E3-ubiquitin ligases in Thick Ascending Limb | 000 | 1 | NIH | 6/11/2025 | $115,500 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R35GM150892 | Subcellular mechanisms coupling lipid synthesis and methionine metabolism | 000 | 3 | NIH | 4/8/2025 | $370,480 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01AG079097 | Profiling Psychosocial Dementia Caregiving Networks: The Impact of Dementia Care Networks on Care Outcomes of Medicare Enrollee Persons Living with Dementia | 000 | 4 | NIH | 5/8/2025 | $405,147 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01CA269607 | Targeted drug delivery system to overcome blood-brain barrier and therapeutic resistance to current standard of care in Glioblastoma | 000 | 4 | NIH | 6/24/2025 | $511,948 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R61MH137105 | Cannabidiol-enhanced cognitive behavioral therapy for generalized anxiety disorder | 000 | 1 | NIH | 5/19/2025 | $1,715,387 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R21AI180183 | The Role of UNG2 Degradation in Antibody Maturation | 000 | 2 | NIH | 4/18/2025 | $228,200 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | K01AG076740 | Maximizing the Scalability of the Chronic Disease Self-Management Program (CDSMP) Among Older Adults in State Correctional Settings | 000 | 3 | NIH | 3/24/2025 | $118,806 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01EY034964 | The Warburg Effect and Diabetic Retinopathy | 000 | 3 | NIH | 4/21/2025 | $385,000 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01ES033171 | Benzene exposure promotes neuroinflammation and metabolic dysregulation | 000 | 4 | NIH | 1/16/2025 | $359,423 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01DK126743 | Molecular and cellular analysis of the ABHD5/PNPLA3 metabolon in lipid homeostasis | 000 | 5 | NIH | 6/23/2025 | $476,166 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01GM146803 | A new paradigm of general transcription factor TFIIB functionality in termination and promoter directionality | 000 | 4 | NIH | 5/19/2025 | $307,648 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R35GM142637 | Spatiotemporal tools to interrogate O-GlcNAc functions in cellular signaling | 000 | 5 | NIH | 4/30/2025 | $360,742 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01EY033516 | Diabetic Retinopathy, Mitochondria Damage and Long Non-coding RNAs | 000 | 4 | NIH | 6/4/2025 | $346,500 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01DK129681 | Infusion device optimization by addressing root causes of the inflammatory response | 001 | 4 | NIH | 6/13/2025 | $51,063 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01DK129681 | Infusion device optimization by addressing root causes of the inflammatory response | 000 | 4 | NIH | 4/9/2025 | $459,580 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01ES036178 | Environmental ethoxylated surfactants and metabolic health dysregulation in zebrafish | 000 | 1 | NIH | 6/2/2025 | $756,318 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01DA052386 | The effects of gestational opioid exposure on the maternal brain, behavior and microbiome | 000 | 4 | NIH | 6/6/2025 | $333,094 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R00CA252152 | Does obesity influence protein quality control in endometrial cancer? | 001 | 5 | NIH | 5/22/2025 | $24,900 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R00CA252152 | Does obesity influence protein quality control in endometrial cancer? | 000 | 5 | NIH | 3/14/2025 | $224,100 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01HD105944 | Intraflagellar transport (IFT) and sperm formation | 000 | 4 | NIH | 2/12/2025 | $478,365 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01ES034410 | Interaction between Genome and Heavy Metals in Nonalcoholic Fatty Liver Disease | 000 | 3 | NIH | 3/19/2025 | $586,862 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01EY026964 | Targeting NAD metabolism to ameliorate bacterial endophthalmitis | 000 | 9 | NIH | 3/17/2025 | $325,703 |
| | 2025 | 2025 | WAYNE STATE UNIVERSITY | 5700 CASS AVE STE 4900 | DETROIT | MI | 48202-3692 | WAYNE | USA | R01DK090313 | A novel CREBH-derived hepatokine regulates triglyceride metabolism | 000 | 13 | NIH | 2/20/2025 | $365,780 |
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