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ABCD-USA Consortium: Data Analysis, Informatics and Resource Center

Award Number: U24DA041123
ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/30/2015
PERIOD OF PERFORMANCE END DATE: 03/31/2027

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ABCD-USA Consortium: Data Analysis, Informatics and Resource Center - Project Summary/Abstract In its initial funding period, the ABCD consortium used a rigorous epidemiological approach to recruit a diverse sample of 11,878 9-10-year-olds through our 21 research sites, of which 2136 are twins or triplets. ABCD has created a comprehensive yet efficient protocol for participating youth and parents, using standardized and state-of-the-art methods for neuroimaging, biospecimens, and assessments of substance use, mental and physical health, neurocognition, culture, and environment, using a fully digital platform and making use of mobile technologies. We ensure cohesion and standardization by having employed a recruitment strategy designed by a professional survey company (experience with Monitoring the Future); standardized environmental, neurocognitive and mental health assessments, MRI assessments with all scanners using harmonized Human Connectome Project procedures, and computerized data collection with real-time quality control. Developmentally tailored assessments will have stable sensitivity and construct validity across the childhood and adolescent developmental period. They minimize participant burden, yet capture even subtle changes over time in substance use, mental health, neurocognition, development, and environment, and we employ novel state-of-the-art bioassays and passive data collection from mobile devices. A detailed retention plan builds on the experience and success of our investigators. This application describes the ABCD Data Analysis, Informatics and Resource Center (DAIRC), which will: maintain and update the harmonized MRI acquisition protocol, compatible with all major scanner platforms, taking advantage of recent technological advances in structural and functional MRI; perform rigorous quality control and quantitative calibration procedures to ensure accuracy and comparability of derived imaging measures across scanners and across time; implement advanced computational analysis workflows for all imaging data; implement reliable data entry, quality control, and monitoring tools for the substance use questionnaire, neurocognitive assessments, bioassay- derived measures, and mobile technologies assessment data; implement the state-of-the-art statistical analysis tools and procedures needed to integrate information across measures and modalities; continue development of infrastructure and procedures for public sharing of raw and derived data and associated tools and computational workflows; and enable interactive data exploration and analytics through a web-based Portal.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $4,481,746 )
2025	2025	J. CRAIG VENTER INSTITUTE, INC.	4120 CAPRICORN LN	LA JOLLA	CA	92037	SAN DIEGO	USA	Drug Use and Addiction Research Programs	004	11	4/10/2025	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$405,546
2025	2025	J. CRAIG VENTER INSTITUTE, INC.	4120 CAPRICORN LN	LA JOLLA	CA	92037	SAN DIEGO	USA	Drug Use and Addiction Research Programs	003	11	3/17/2025	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$4,076,200
2025	2024	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	001	10	3/17/2025	NON-COMPETING CONTINUATION	$0
2025	2024	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	002	10	3/17/2025	SUPPLEMENT FOR EXPANSION	$0
2025	2024	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	000	10	2/14/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $4,481,746

Issue Date FY: 2024 ( Subtotal = $6,662,763 )
2024	2024	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	004	10	5/13/2024	NON-COMPETING CONTINUATION	$0
2024	2024	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	005	10	7/25/2024	NON-COMPETING CONTINUATION	$90,345
2024	2024	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	006	10	9/3/2024	SUPPLEMENT FOR EXPANSION	$2,900,000
2024	2024	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	003	10	4/15/2024	NON-COMPETING CONTINUATION	$3,672,418
2024	2023	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	001	9	10/13/2023	NON-COMPETING CONTINUATION	$0
2024	2023	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	002	9	1/10/2024	NON-COMPETING CONTINUATION	$0
2024	2022	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	000	8	10/12/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $6,662,763

Issue Date FY: 2023 ( Subtotal = $6,262,762 )
2023	2023	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	001	9	5/19/2023	SUPPLEMENT FOR EXPANSION	$2,499,999
2023	2023	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	000	9	3/23/2023	NON-COMPETING CONTINUATION	$3,762,763
2023	2022	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	002	8	7/21/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $6,262,762

Issue Date FY: 2022 ( Subtotal = $3,763,088 )
2022	2022	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	000	8	3/31/2022	NON-COMPETING CONTINUATION	$3,763,088
														Subtotal = $3,763,088

Issue Date FY: 2021 ( Subtotal = $4,214,231 )
2021	2021	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	004	7	4/13/2021	SUPPLEMENT FOR EXPANSION	$291,722
2021	2021	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	005	7	9/7/2021	NON-COMPETING CONTINUATION	$0
2021	2021	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	003	7	4/12/2021	NON-COMPETING CONTINUATION	$3,922,509
2021	2020	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	000	6	12/21/2020	COMPETING CONTINUATION	$0
2021	2020	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	002	6	3/10/2021	COMPETING CONTINUATION	$201,953
2021	2019	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	001	5	3/10/2021	NON-COMPETING CONTINUATION	-$201,953
														Subtotal = $4,214,231

Issue Date FY: 2020 ( Subtotal = $3,958,758 )
2020	2020	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	003	6	8/27/2020	SUPPLEMENT FOR EXPANSION	$0
2020	2020	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	002	6	5/1/2020	SUPPLEMENT FOR EXPANSION	$157,500
2020	2020	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	001	6	4/14/2020	COMPETING CONTINUATION	$3,801,258
2020	2019	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	000	5	4/13/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $3,958,758

Issue Date FY: 2019 ( Subtotal = $2,760,489 )
2019	2019	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	001	5	7/29/2019	NON-COMPETING CONTINUATION	$0
2019	2019	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	000	5	4/16/2019	NON-COMPETING CONTINUATION	$2,760,489
														Subtotal = $2,760,489

Issue Date FY: 2018 ( Subtotal = $2,726,393 )
2018	2018	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	000	4	4/25/2018	NON-COMPETING CONTINUATION	$2,726,393
														Subtotal = $2,726,393

Issue Date FY: 2017 ( Subtotal = $3,023,259 )
2017	2017	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	001	3	7/7/2017	SUPPLEMENT FOR EXPANSION	$145,760
2017	2017	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	002	3	9/14/2017	SUPPLEMENT FOR EXPANSION	$100,000
2017	2017	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	000	3	6/14/2017	NON-COMPETING CONTINUATION	$2,777,499
														Subtotal = $3,023,259

Issue Date FY: 2016 ( Subtotal = $2,936,270 )
2016	2016	UNIVERSITY OF CALIFORNIA-SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	000	2	6/1/2016	NON-COMPETING CONTINUATION	$2,764,270
2016	2016	UNIVERSITY OF CALIFORNIA-SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	001	2	9/1/2016	SUPPLEMENT FOR EXPANSION	$172,000
														Subtotal = $2,936,270

Issue Date FY: 2015 ( Subtotal = $1,532,349 )
2015	2015	UNIVERSITY OF CALIFORNIA-SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Drug Use and Addiction Research Programs	000	1	9/25/2015	NEW	$1,532,349
														Subtotal = $1,532,349

Grand Total All Awards = $42,322,108

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ABCD-USA Consortium: Data Analysis, Informatics and Resource Center

Award Number: U24DA041123

ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/30/2015

PERIOD OF PERFORMANCE END DATE: 03/31/2027

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