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 | Issue Date FY: 2025 ( Subtotal = $585,389,749 ) (Continued on the next page) |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | OT2OD040415 | Elucidating the Interplay of Genes and Environment in Autism Using Genomic and Exposure Data from Large Populations | 000 | 1 | NIH | 9/19/2025 | $1,972,770 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | F31NS147852 | Applying spatial transcriptomics and mouse molecular genetics to understand the mechanisms of fibrotic scarring for promoting neural repair after spinal cord injury | 000 | 1 | NIH | 9/19/2025 | $42,870 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | F30HL178290 | Mechanism of cardioprotective mitochondrial oxidative stress priming in doxorubicin-induced cardiotoxicity | 000 | 1 | NIH | 9/5/2025 | $42,596 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R00AA031328 | Role of gut microbial ethanol production in alcohol use disorder and alcohol-associated liver disease | 000 | 3 | NIH | 9/15/2025 | $248,981 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | RF1AG095193 | Human neuropeptide transmitter systems are dysregulated in Alzheimer's disease pathogenesis | 000 | 1 | NIH | 9/5/2025 | $3,138,871 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01AI192662 | Skin microbes and development of allergic disease | 000 | 1 | NIH | 9/5/2025 | $5,176,858 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01HL180754 | Protein Aggregation in Hematopoietic Stem Cells | 000 | 1 | NIH | 9/12/2025 | $536,468 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | K08HL173682 | Role of KLF6 in Lung Development | 000 | 1 | NIH | 8/29/2025 | $173,259 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01DK141973 | Renal Metabolism in AKI | 000 | 1 | NIH | 9/12/2025 | $2,833,514 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | U01DK143381 | Utilizing continuous ketone monitors to enable safe use of SGLT inhibitors in patients with Type 1 Diabetes | 000 | 1 | NIH | 9/10/2025 | $2,257,919 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | OT2OD032619 | SPARC Engagement Plan with the Common Fund Data Ecosystem | 001 | 1 | NIH | 9/10/2025 | $349,999 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01AR086616 | Role of lysine acetylation in skeletal muscle contractile function | 000 | 1 | NIH | 9/12/2025 | $1,853,872 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01GM158907 | Innovative drug design technologies from computational mapping of energy, entropy, and free energy in proteins and protein-ligand systems | 000 | 1 | NIH | 9/8/2025 | $638,334 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | K00EY038170 | Characterizing individual differences in toddlers' information seeking during naturalistic play | 000 | 2 | NIH | 9/8/2025 | $52,322 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | F32GM157932 | De novo design of artificial haloperoxidase enzymes | 000 | 1 | NIH | 8/29/2025 | $75,052 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | K00EY038170 | Characterizing individual differences in toddlers' information seeking during naturalistic play | 000 | 2 | NIH | 9/8/2025 | $29,296 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | RF1NS144660 | Mechanism of ALS/FTD determined by multimodal single cell spatial transcriptomics | 000 | 1 | NIH | 9/11/2025 | $3,081,936 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R37CA239072 | Regulation of PD-L1/PD-1 immune checkpoints by cis-interactions | 002 | 7 | NIH | 6/25/2025 | $35,391 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R37CA239072 | Regulation of PD-L1/PD-1 immune checkpoints by cis-interactions | 001 | 7 | NIH | 2/13/2025 | $318,535 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01NS131151 | Developing a Synthetic Adeno-Associated Virus (AAV) for Engineering Safer Gene Therapies | 000 | 3 | NIH | 1/27/2025 | $386,587 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01HL166485 | The cardiovascular consequences of sleep apnea plus COPD (Overlap syndrome) | 001 | 3 | NIH | 8/9/2025 | $776,366 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R33DA060426 | Evaluating Vending Machines providing Naloxone to Prevent Overdose in American Indian Communities | 000 | 2 | NIH | 8/8/2025 | $702,245 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01CA251414 | FEN1-Nuclease-Targeted Therapy for Ewing Sarcoma | 001 | 5 | NIH | 5/23/2025 | $62,429 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | K99DA060978 | From Childhood to Adulthood: the Co-occurrence of Trauma, Substance Use, and Additional Stressors | 000 | 1 | NIH | 6/20/2025 | $158,246 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01CA251414 | FEN1-Nuclease-Targeted Therapy for Ewing Sarcoma | 000 | 5 | NIH | 3/11/2025 | $561,859 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | F32HL178303 | Tissue elasticity and viscosity modulates macrophage-fibroblast signaling in cardiac fibrosis | 001 | 1 | NIH | 3/17/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | F32HL178303 | Tissue elasticity and viscosity modulates macrophage-fibroblast signaling in cardiac fibrosis | 002 | 1 | NIH | 6/23/2025 | $1,284 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | F32HL178303 | Tissue elasticity and viscosity modulates macrophage-fibroblast signaling in cardiac fibrosis | 000 | 1 | NIH | 3/17/2025 | $76,756 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | K08NS123543 | Defining the forebrain neurophysiological representation of pain | 000 | 3 | NIH | 2/17/2025 | $195,561 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R21AI187952 | Immune adaptations in acute pouchitis | 000 | 1 | NIH | 7/17/2025 | $409,320 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | U24DK097771 | dkNET Coordinating Unit: Harnessing the Power of AI and Data Science forCollaborative Discovery and Sharing in the DK Community | 003 | 12 | NIH | 9/5/2025 | $494,250 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | U24DK097771 | dkNET Coordinating Unit: Harnessing the Power of AI and Data Science forCollaborative Discovery and Sharing in the DK Community | 002 | 12 | NIH | 4/17/2025 | $2,000,000 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | F31AI194603 | Mechanisms of gene regulation in bacterial defense islands | 001 | 1 | NIH | 7/17/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | F31AI194603 | Mechanisms of gene regulation in bacterial defense islands | 000 | 1 | NIH | 7/17/2025 | $45,982 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01HL173155 | Blood Pressure Control Advancing Refugee Health Equity (BPCARE): an RCT of adherence | 000 | 1 | NIH | 7/17/2025 | $688,525 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01DA062216 | Strengthening Text-based Warning Labels on Cannabis Edible Packages | 000 | 1 | NIH | 7/10/2025 | $811,679 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R21AI186034 | Applied Metatranscriptomics and Metatranslatomics to identify new mechanisms of Salmonella-microbiota competition | 000 | 2 | NIH | 3/11/2025 | $178,331 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01DE035393 | Targeting Systems Vulnerabilities in the EGFR/HER3/HER2 Oncogenic Signaling Circuitry: New Precision Therapies for Oral Cancer | 000 | 1 | NIH | 6/26/2025 | $483,360 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R21DE035344 | A Chairside Diagnostic to Reduce the Need for Endodontic Retreatment | 000 | 1 | NIH | 6/25/2025 | $443,490 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01ES025792 | Cyclical Alterations In Neurocognitive Performance And Mood Over Two Years In Relation To Pesticide Spray Seasons Among Adolescent And Young Adult Participants Of The Espina Study. | 000 | 9 | NIH | 3/10/2025 | $600,662 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01NS139872 | Development of photocaged DREADD agonists for high-efficiency, target-specific optical silencing of synaptic transmission | 000 | 1 | NIH | 1/31/2025 | $1,124,850 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | U01AG088051 | Development of a MT-stabilizing agent for the treatment of tauopathies | 002 | 2 | NIH | 8/18/2025 | $2,250,355 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R35GM156288 | Regulated assembly and function of macromolecular complexes in genome maintenance | 000 | 1 | NIH | 1/31/2025 | $254,919 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R25MH108389 | Sustained Training in Aging and HIV Research (STAHR) | 000 | 8 | NIH | 3/13/2025 | $209,974 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01AG087407 | Intrinsic CSF outflow metrics for mild cognitive impairment and Alzheimer's disease | 001 | 2 | NIH | 8/11/2025 | $61,164 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01AG087407 | Intrinsic CSF outflow metrics for mild cognitive impairment and Alzheimer's disease | 000 | 2 | NIH | 2/14/2025 | $688,104 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01HL161361 | CRISPR-based transistors for high throughput multiplexed monitoring of CRISPR-based editing efficiency for Sickle cell disease | 001 | 4 | NIH | 7/24/2025 | $43,134 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01HL161361 | CRISPR-based transistors for high throughput multiplexed monitoring of CRISPR-based editing efficiency for Sickle cell disease | 000 | 4 | NIH | 3/3/2025 | $388,206 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01DK136117 | Reverse Metabolomics for the Discovery of Disease Associated Microbial Molecules | 001 | 3 | NIH | 5/19/2025 | $72,982 |
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