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 | Issue Date FY: 2025 ( Subtotal = $447,231,774 ) (Continued on the next page) |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | RF1MH129979 | Endothelial monoamine neurotransmitter metabolism at the blood-brain barrier | 000 | 4 | NIH | 8/6/2025 | $790,000 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01HL178857 | Mechanisms of Cardiac Myosin Heavy Chain Gene Regulation | 000 | 1 | NIH | 7/31/2025 | $761,152 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01AR085008 | Ultrashort Echo Time Magnetic Resonance Imaging of the Knee Joint | 000 | 1 | NIH | 7/25/2025 | $675,131 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R35GM156889 | Flows, Fates and Forces: A Biophysical Framework for Data-Driven Discovery in Development | 000 | 1 | NIH | 7/23/2025 | $327,019 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | F32DA064409 | Developmental Brain Connectomes and Substance Use in Adolescence | 001 | 1 | NIH | 7/23/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | F31NS145649 | LRRK2-specific DARPins as tools to investigate kinase activation and regulation in Parkinson's Disease | 000 | 1 | NIH | 7/29/2025 | $42,596 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | F32DA064409 | Developmental Brain Connectomes and Substance Use in Adolescence | 000 | 1 | NIH | 7/23/2025 | $75,052 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | U01AG094588 | In vitro pharmacology, chronic toxicology, and embryo-fetal development studies to demonstrate safety of GSM-779690 | 000 | 1 | NIH | 7/31/2025 | $1,612,640 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R21DA062721 | Trajectories of social isolation and loneliness among older adults living with HIV who use methamphetamine | 000 | 1 | NIH | 7/31/2025 | $198,854 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R21HD117178 | Identification of a cellular immune signature unique to clinically-significant villitis of unknown etiology | 000 | 1 | NIH | 7/21/2025 | $452,000 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | K23HL181397 | Optimal Ventilator Management in Patients with ARDS on ECMO | 000 | 1 | NIH | 7/25/2025 | $178,846 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | F31DA063338 | Evaluating the Multiscale Effects of Fentanyl-Induced Dependence and Abstinence within the Mouse Basolateral Amygdala | 001 | 1 | NIH | 7/21/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R37CA288506 | Targeting T Cells for enhancing anti-tumor immunity in pediatric brain tumors. | 000 | 1 | NIH | 7/25/2025 | $546,308 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01HG010885 | Systematic characterization of tandem repeat variants contributing to complex traits | 001 | 6 | NIH | 7/28/2025 | $634,178 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01HL162302 | AMPK Regulation of ACE2 in Endothelial Health and Disease | 000 | 4 | NIH | 2/27/2025 | $591,251 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01MH134120 | Chronobiological Basis of Depression during the Menopause Transition | 000 | 2 | NIH | 3/14/2025 | $668,102 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | P30MH062512 | HIV Neurobehavioral Research Center | 000 | 25 | NIH | 2/13/2025 | $1,499,994 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01HL132141 | A novel treatment of aortic disease in Marfan Syndrome targeting oxidative stress and PKG dysregulation | 001 | 8 | NIH | 7/17/2025 | $73,162 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01HL132141 | A novel treatment of aortic disease in Marfan Syndrome targeting oxidative stress and PKG dysregulation | 000 | 8 | NIH | 3/4/2025 | $658,459 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | UM1TR005449 | CTSA UM1 Program at University of California San Diego Altman Clinical and Translational Research Institute | 001 | 1 | NIH | 8/12/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R35GM158085 | Analysis of active genetic elements in germline and somatic cell lineages | 000 | 1 | NIH | 7/28/2025 | $376,498 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | UM1TR005449 | CTSA UM1 Program at University of California San Diego Altman Clinical and Translational Research Institute | 000 | 1 | NIH | 7/23/2025 | $10,325,540 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01HL181539 | Biological Mechanisms of the Infarct Borderzone | 000 | 1 | NIH | 7/28/2025 | $765,288 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | F31NS141340 | Hunger-dependent modulation of neural circuits for social visuomotor processing in schooling fish | 000 | 1 | NIH | 7/31/2025 | $42,913 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | F99CA305515 | From T Cells to Dendritic Cells: Mechanistic Dissection of CTLA4 and TIM3 in Cancer Immunity | 000 | 1 | NIH | 7/29/2025 | $47,096 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R37NS112503 | Mechanism of stathmin-2-dependent axon maintenance, regeneration, and function | 000 | 7 | NIH | 7/30/2025 | $3,495,400 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R21CA306070 | 3D High Density Collagen I Improves Modeling of Metastatic Pancreatic Cancer | 000 | 1 | NIH | 7/31/2025 | $410,115 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01AI190001 | Conditional and female lethal approaches for mosquito control | 000 | 1 | NIH | 7/21/2025 | $588,514 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01GM148476 | Recognition of Synthetic Unnatural Base Pairs by RNA Polymerase | 001 | 3 | NIH | 8/7/2025 | $40,379 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01GM148476 | Recognition of Synthetic Unnatural Base Pairs by RNA Polymerase | 000 | 3 | NIH | 2/17/2025 | $363,427 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01CA257505 | Targeting Systems Vulnerabilities in the Gαq/GNAQ Oncogenic Signaling Circuitry: New Precision Therapies for Uveal Melanoma | 001 | 5 | NIH | 5/22/2025 | $52,211 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01CA257505 | Targeting Systems Vulnerabilities in the Gαq/GNAQ Oncogenic Signaling Circuitry: New Precision Therapies for Uveal Melanoma | 000 | 5 | NIH | 3/6/2025 | $469,899 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | U24DK138512 | An interactive resource to generate and provide integrated knowledge of the human pancreas | 000 | 2 | NIH | 2/19/2025 | $1,714,904 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R21AI193549 | Mechanisms that underpin immunoglobulin gene rearrangement | 000 | 1 | NIH | 7/8/2025 | $438,500 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01HG012351 | Next generation massively multiplexed combinatorial genetic screens | 001 | 3 | NIH | 4/25/2025 | $67,881 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01HG012351 | Next generation massively multiplexed combinatorial genetic screens | 000 | 3 | NIH | 3/20/2025 | $610,933 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | K23DK134880 | Reducing Hyperinsulinemia and Insulin Resistance in Type 1 Diabetes Using Adjunctive Therapies | 000 | 2 | NIH | 2/19/2025 | $197,208 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | K23DK132680 | Non Invasive Assessment of Microcirculation Function and Kidney Disease | 000 | 4 | NIH | 2/19/2025 | $194,037 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01MH106595 | Psychiatric Genomics Consortium for PTSD | 002 | 10 | NIH | 3/19/2025 | $204,864 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01DA053372 | Effect of methadone on the developmental properties of human brain organoids | 001 | 4 | NIH | 4/10/2025 | $62,026 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01DA053372 | Effect of methadone on the developmental properties of human brain organoids | 000 | 4 | NIH | 2/26/2025 | $558,239 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R61MH129380 | Targeting Dopamine-Mediated Social Reward Sensitivity to Remediate Social Disconnection | 001 | 2 | NIH | 7/31/2025 | $210,205 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01CA241728 | Bacterial biosensors for the prevention of gastrointestinal cancers | 003 | 6 | NIH | 8/11/2025 | $120,024 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | U01NS126054 | Optimization of Calcium and RNA multiplexed activity imaging for highly parallelized evaluation of cell type functions in deep-brain structures | 001 | 4 | NIH | 7/15/2025 | $639,097 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R61MH129380 | Targeting Dopamine-Mediated Social Reward Sensitivity to Remediate Social Disconnection | 000 | 2 | NIH | 3/6/2025 | $1,191,148 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R01HL170002 | Molecular basis of ASNA1 cardiomyopathy | 000 | 2 | NIH | 2/25/2025 | $491,573 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R21AI188166 | Sequence specific determinants, and impacts, of NS2 interactions with the influenza A virus polymerase | 000 | 1 | NIH | 7/8/2025 | $438,500 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | R00HL168365 | p16INK4a+ fibroblasts regulate epithelial regeneration after injury in lung alveoli through the SASP | 001 | 4 | NIH | 6/16/2025 | $248,995 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA, SAN DIEGO | 9500 GILMAN DR | LA JOLLA | CA | 92093-0021 | SAN DIEGO | USA | U01DA056006 | Single Cell Transcriptomics of the Cocaine Use Disorder in the Context of HIV | 001 | 4 | NIH | 3/31/2025 | $1,690,196 |
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