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Alliance for Clinical Trials in Oncology Operations Center

Award Number: U10CA180821
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 04/17/2014
PERIOD OF PERFORMANCE END DATE: 02/29/2032

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Alliance for Clinical Trials in Oncology Operations Center - PROJECT SUMMARY/ABSTRACT The Alliance for Clinical Trials in Oncology is an experienced multi-institutional cancer clinical trials group that develops and conducts clinical trials with promising new cancer therapies by utilizing the best science to develop optimal treatment and prevention strategies for cancer, as well as research methods to alleviate side effects of cancer and cancer treatments. The Alliance provides a comprehensive and highly efficient clinical trials infrastructure, access to experienced collaborators across all disciplines of oncology clinical trials research, and a diverse portfolio of trials for patients with breast, gastrointestinal, genitourinary, respiratory, central nervous system, hematological malignancies, in addition to rare tumors. Particular strengths of the Alliance include the long-standing tradition of collaborative research of the legacy members, its focus on science, innovation and mentorship, its successful track record in developing multidisciplinary therapeutic solutions for cancer patients, its seamless incorporation of correlative science for the discovery of prognostic and predictive biomarkers, and its commitment to special patient populations including minority and underserved populations. The Mission of the Alliance for Clinical Trials in Oncology is to reduce the impact of cancer by: • Conducting high quality multidisciplinary cancer control, prevention, and treatment trials that engage a comprehensive research network; • Furthering our understanding of the biological basis of the cancer process and its treatment; from discovery, to validation, to clinical practice; • Providing a scientific and operational infrastructure for innovative clinical and translational research in the academic and community settings.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $10,090,432 )
2026	2026	ALLIANCE NCTN FOUNDATION	311 S WACKER DR STE 2650	CHICAGO	IL	60606	COOK	USA	Cancer Treatment Research	001	12	6/23/2026	COMPETING CONTINUATION	$6,719,624
2026	2026	ALLIANCE NCTN FOUNDATION	311 S WACKER DR STE 2650	CHICAGO	IL	60606	COOK	USA	Cancer Treatment Research	004	12	9/15/2026	COMPETING CONTINUATION	$3,370,808
2026	2026	ALLIANCE NCTN FOUNDATION	311 S WACKER DR STE 2650	CHICAGO	IL	60606	COOK	USA	Cancer Treatment Research	003	12	9/10/2026	COMPETING CONTINUATION	$0
2026	2024	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	000	11	4/22/2026	NON-COMPETING CONTINUATION	$0
2026	2024	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	002	11	7/6/2026	NON-COMPETING CONTINUATION	$0
														Subtotal = $10,090,432

Issue Date FY: 2025 ( Subtotal = $12,431,077 )
2025	2025	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	004	11	4/16/2025	SUPPLEMENT FOR EXPANSION	$3,950,153
2025	2025	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	006	11	9/16/2025	SUPPLEMENT FOR EXPANSION	$623,526
2025	2025	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	005	11	9/15/2025	SUPPLEMENT FOR EXPANSION	$7,863,323
2025	2024	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	003	11	4/9/2025	NON-COMPETING CONTINUATION	$0
2025	2024	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	000	11	10/23/2024	NON-COMPETING CONTINUATION	$0
2025	2024	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	001	11	3/4/2025	NON-COMPETING CONTINUATION	$0
2025	2023	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Control	002	9	3/13/2025	SUPPLEMENT FOR EXPANSION	-$5,925
														Subtotal = $12,431,077

Issue Date FY: 2024 ( Subtotal = $10,362,227 )
2024	2024	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	001	11	2/19/2024	NON-COMPETING CONTINUATION	$6,878,833
2024	2024	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	004	11	9/13/2024	SUPPLEMENT FOR EXPANSION	$40,907
2024	2024	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	003	11	4/16/2024	NON-COMPETING CONTINUATION	$621,762
2024	2024	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	002	11	3/20/2024	SUPPLEMENT FOR EXPANSION	$1,131,435
2024	2024	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	005	11	9/19/2024	NON-COMPETING CONTINUATION	$1,689,290
2024	2023	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	000	10	1/30/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $10,362,227

Issue Date FY: 2023 ( Subtotal = $14,681,047 )
2023	2023	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	007	10	8/28/2023	SUPPLEMENT FOR EXPANSION	$777,919
2023	2023	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	006	10	8/22/2023	NON-COMPETING CONTINUATION	$1,697,155
2023	2023	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	005	10	5/26/2023	SUPPLEMENT FOR EXPANSION	$1,529,099
2023	2023	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	003	10	4/24/2023	NON-COMPETING CONTINUATION	$576,000
2023	2023	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	008	10	8/29/2023	NON-COMPETING CONTINUATION	$300,000
2023	2023	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	001	10	3/14/2023	NON-COMPETING CONTINUATION	$6,960,799
2023	2023	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	004	10	5/1/2023	SUPPLEMENT FOR EXPANSION	$2,046,686
2023	2023	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Control	000	9	1/11/2023	SUPPLEMENT FOR EXPANSION	$817,650
2023	2018	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	002	5	3/20/2023	NON-COMPETING CONTINUATION	-$24,261
														Subtotal = $14,681,047

Issue Date FY: 2022 ( Subtotal = $13,882,110 )
2022	2022	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	011	9	9/14/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2022	BRIGHAM AND WOMEN'S HOSPITAL, INC., THE	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	002	9	4/22/2022	SUPPLEMENT FOR EXPANSION	$2,408,803
2022	2022	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	007	9	8/16/2022	NON-COMPETING CONTINUATION	$1,099,268
2022	2022	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	009	9	9/14/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2022	BRIGHAM AND WOMEN'S HOSPITAL, INC., THE	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	001	9	4/14/2022	NON-COMPETING CONTINUATION	$0
2022	2022	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	006	9	8/10/2022	NON-COMPETING CONTINUATION	$2,041,024
2022	2022	BRIGHAM AND WOMEN'S HOSPITAL, INC., THE	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	004	9	7/15/2022	NON-COMPETING CONTINUATION	$0
2022	2022	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	008	9	8/24/2022	SUPPLEMENT FOR EXPANSION	$207,570
2022	2022	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	013	9	9/15/2022	NON-COMPETING CONTINUATION	$0
2022	2022	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	012	9	9/14/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2022	BRIGHAM AND WOMEN'S HOSPITAL, INC., THE	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	003	9	6/24/2022	SUPPLEMENT FOR EXPANSION	$1,400,000
2022	2022	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	010	9	9/14/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2022	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	005	9	7/29/2022	SUPPLEMENT FOR EXPANSION	$1,221,951
2022	2022	BRIGHAM AND WOMEN'S HOSPITAL, INC., THE	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	000	9	3/17/2022	NON-COMPETING CONTINUATION	$5,503,494
														Subtotal = $13,882,110

Issue Date FY: 2021 ( Subtotal = $13,914,145 ) (Continued on the next page)
2021	2021	BRIGHAM AND WOMEN'S HOSPITAL, INC., THE	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	001	8	3/1/2021	NON-COMPETING CONTINUATION	$8,332,715
2021	2021	BRIGHAM AND WOMEN'S HOSPITAL, INC., THE	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	004	8	6/7/2021	NON-COMPETING CONTINUATION	$2,000,000
2021	2021	BRIGHAM AND WOMEN'S HOSPITAL, INC., THE	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	003	8	5/13/2021	NON-COMPETING CONTINUATION	$0
Grand Total All Awards = $167,207,857

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Alliance for Clinical Trials in Oncology Operations Center

Award Number: U10CA180821

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 04/17/2014

PERIOD OF PERFORMANCE END DATE: 02/29/2032

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