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 | Issue Date FY: 2026 ( Subtotal = $13,957,965 ) (Continued on the next page) |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI136041 | Eicosanoid Networks in Aspirin Hypersensitivity | 000 | 13 | NIH | 12/3/2025 | $656,461 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K00CA274651 | Development of Lipid Nanoparticles for B-cell Mediated Immunotherapies | 000 | 4 | NIH | 12/10/2025 | $80,231 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UM1AI069412 | Boston HIV CTU | 000 | 20 | NIH | 12/9/2025 | $2,578,146 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R37AI139536 | Neuroimmune interactions regulate development of allergic inflammation | 000 | 8 | NIH | 12/2/2025 | $602,703 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21HD117308 | Continuous Non-Invasive Blood Pressure Monitoring in Neonates using Wearable Wireless NIRS | 000 | 2 | NIH | 12/12/2025 | $234,746 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01NS136297 | Optimizing Neuromodulation Therapies for Epilepsy: Identifying the Right Patient, Right Place, and Right Time for Stimulation | 000 | 2 | NIH | 12/12/2025 | $590,408 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01MH132632 | Control of ETV1 transcriptional networks in amygdalar astrocytes | 000 | 3 | NIH | 12/3/2025 | $434,860 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HD113792 | Mechanics of Vertebrate Embryo Elongation | 000 | 3 | NIH | 12/15/2025 | $567,127 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01EB035091 | Abbreviated yet enhanced neuro MRI protocol | 000 | 2 | NIH | 12/5/2025 | $384,451 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01ES034079 | Geospatially modeled environmental risk factors for lymphoid malignancies | 000 | 3 | NIH | 12/9/2025 | $687,459 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DK141535 | The role of SRCAP in therapy related clonal hematopoiesis | 000 | 2 | NIH | 12/15/2025 | $508,759 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DK039773 | Mechanisms of Ischemic Kidney Injury and Repair | 000 | 39 | NIH | 12/15/2025 | $712,313 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA288535 | Cell surface receptor targeted therapies for brain tumors | 000 | 2 | NIH | 12/18/2025 | $370,543 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI187513 | Rapid point of care Hepatitis C virus detection using a long-lasting luminescent cascade signal amplification | 000 | 2 | NIH | 12/4/2025 | $875,816 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI176341 | A TCF1:Glucocorticoid regulatory circuit controls IL-23-driven Th17 pathogenicity | 000 | 4 | NIH | 12/10/2025 | $517,503 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI175582 | Skin vaccination and generation of protective lung-tropic memory T cells | 000 | 3 | NIH | 11/26/2025 | $940,602 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI181221 | Interrogating Clonal Repertoire in Drug Hypersensitivity Reactions | 000 | 3 | NIH | 12/5/2025 | $865,521 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI179807 | Harnessing commensal redox metabolism in infection prevention | 000 | 3 | NIH | 12/4/2025 | $849,858 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI179986 | The novel role of MIF-CD74 inflammatory pathway in immune regulation | 000 | 3 | NIH | 12/5/2025 | $420,683 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG082346 | Mechanisms of Somatic Mutation in Alzheimer's Disease Using Single Neuron Analysis | 000 | 3 | NIH | 12/11/2025 | $804,192 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08NS136723 | Immune Regulation of the Blood-Brain Barrier | 000 | 2 | NIH | 12/17/2025 | $230,580 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K24AI180296 | Patient-Oriented Research Mentorship and Training in Upper Airway Allergic and Inflammatory Diseases | 000 | 3 | NIH | 12/10/2025 | $174,031 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23MD016129 | Improving Outcomes for Spanish-Speaking Surgical Patients with Limited English Proficiency | 000 | 4 | NIH | 12/9/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23HL171893 | Interplay of Inflammation, Angiogenesis, and Coronary Microvascular Perfusion in Advanced Kidney Disease | 000 | 1 | NIH | 12/3/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08DE030216 | Development of an artificial intelligence-driven, imaging-based platform for pretreatment identification of extranodal extension in head and neck cancer | 000 | 5 | NIH | 10/22/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K01DA061975 | Dynamic Treatment Regimes for Personalized Opioid Use Disorder Care | 000 | 1 | NIH | 12/3/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UG3TR005836 | An Aging Alveolar Lung Model in Microgravity | 000 | 1 | NIH | 12/10/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | U54AG062322 | Center for Stress and Neural Regulation of Reproductive Aging Health Outcomes | 000 | 6 | NIH | 11/26/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | U19CA264504 | Harvard/Stanford GTN Program: Novel targeted therapeutics for glioblastoma | 000 | 5 | NIH | 12/5/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | U01AG089040 | Development, Validation, and Harmonization of Methods for Collection and Measurement of NAD+ and Related Metabolites: Application to a Randomized Trial of Patients Undergoing Coronary Artery Bypass | 000 | 2 | NIH | 12/3/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | U01AI186972 | Harnessing Trained Immunity as a Radiation Medical Countermeasure | 000 | 1 | NIH | 11/26/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | U01CA268810 | Polygenic risk stratification combined with mpMRI to identify clinically relevant prostate cancer | 000 | 3 | NIH | 12/15/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R34HL178960 | Antihypertensive self-titration to improve US blood pressure control | 000 | 1 | NIH | 12/10/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL162102 | Menstrual-phase-dependent differences in response to chronic variable sleep loss | 000 | 4 | NIH | 12/13/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL160799 | Targeting the Active Resolution of Inflammation for Cardiovascular Disease Prevention | 000 | 4 | NIH | 10/7/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL161087 | Skin-Intrinsic Immunosuppressive Mesenchymal Stem Cells and aGVHD | 000 | 4 | NIH | 12/9/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01EY022445 | Use of Correlated Data Methods in Ophthalmology | 000 | 10 | NIH | 10/30/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01EB032387 | Ultrasound based neurosurgical navigation with uncertainty visualization | 000 | 4 | NIH | 12/17/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DK126855 | "A microbiome-dependent bile acid metabolite improves type 2 diabetes." | 000 | 5 | NIH | 12/1/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA241817 | Development of Methods for a Simplified and Reliable Prostate Cancer MRI Exam | 000 | 5 | NIH | 12/16/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI153605 | Commensal control of C. difficile virulence | 000 | 5 | NIH | 12/17/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | P41EB028741 | Advanced Technologies - National Center for Image Guided Therapy (AT-NCIGT) | 000 | 5 | NIH | 10/8/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23AT012475 | App-guided bedtime mindfulness for insomnia | 000 | 2 | NIH | 12/15/2025 | $0 |
| | 2026 | 2024 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23MH120324 | Toward optimizing digital mental health interventions: A clinical trial aimed at understanding what drives patient engagement. | 000 | 5 | NIH | 12/4/2025 | $0 |
| | 2026 | 2024 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K12HD103096 | Transdisciplinary Harvard WRHR Career Development for Gynecologists and Obstetricians | 000 | 5 | NIH | 12/15/2025 | -$72,871 |
| | 2026 | 2024 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08HL151976 | Ubiquitination and Endothelial Fibrosis in Early Pulmonary Arterial Hypertension | 000 | 5 | NIH | 12/18/2025 | -$1,572 |
| | 2026 | 2024 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | T35AG038027 | Greater Boston Medical Student Training in Aging Research | 000 | 15 | NIH | 12/9/2025 | $0 |
| | 2026 | 2024 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | T32HL094301 | Noninvasive Cardiovascular Imaging Research Training Program | 000 | 15 | NIH | 12/5/2025 | $0 |
| | 2026 | 2024 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21DC020777 | A Multi-omics Investigation of Incident Persistent Tinnitus | 000 | 3 | NIH | 12/10/2025 | $0 |
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