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 | Issue Date FY: 2026 ( Subtotal = $123,264,275 ) (Continued on the next page) |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HD107772 | Safety of Benzodiazepines and Non-Benzodiazepine Sedative Hypnotics in Pregnancy | 000 | 5 | NIH | 5/7/2026 | $619,665 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R13AT013876 | The Science of Tai Chi & Qigong as Whole Person Health: Deepening Our Physiological Understanding of the Mind-Body Connection | 000 | 1 | NIH | 5/7/2026 | $30,000 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R13AT013876 | The Science of Tai Chi & Qigong as Whole Person Health: Deepening Our Physiological Understanding of the Mind-Body Connection | 000 | 1 | NIH | 5/7/2026 | $15,000 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23HL166686 | Personalized Exercise Training to Improve Functional Capacity in Transthyretin Cardiac Amyloidosis | 000 | 4 | NIH | 4/28/2026 | $184,537 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG077489 | Towards Precision Nutrition for Alzheimer's Dementia Prevention: A Prospective Study of Dietary Patterns, the Gut Microbiome and Cognitive Function | 000 | 5 | NIH | 4/7/2026 | $865,792 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA279410 | MMS22L loss and PARP inhibition in prostate cancer | 000 | 4 | NIH | 4/7/2026 | $409,463 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21HD117308 | Continuous Non-Invasive Blood Pressure Monitoring in Neonates using Wearable Wireless NIRS | 001 | 2 | NIH | 4/2/2026 | $26,083 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI175149 | Prostaglandin E2-Dependent Control of a Mast Cell IL-33/ST2 Pathway in Asthma | 000 | 4 | NIH | 4/1/2026 | $859,874 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08HD116931 | The role of AgRP neurons in the metabolic and reproductive complications of Cushing's Syndrome | 000 | 1 | NIH | 4/27/2026 | $167,400 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL178823 | Extending neutrophil survival in neutropenia-related pneumonia | 000 | 2 | NIH | 4/2/2026 | $663,213 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL135142 | Genetic and Genomic Characterization of the Occurrence and Progression of Interstitial Lung Abnormalities | 000 | 7 | NIH | 4/2/2026 | $1,582,806 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01EB037010 | Development of a multifunctional interventional device for biopsy and optical imaging-based phase-0 drug response measurements | 000 | 1 | NIH | 4/28/2026 | $749,901 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01NS088137 | Targeting TGFb/IFNy-IRF8 Signaling to Modulate Monocytes and their Crosstalk with Microglia and Astrocytes to Treat Multiple Sclerosis | 000 | 12 | NIH | 4/13/2026 | $644,207 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23NS136767 | Predicting Dependency after Traumatic Brain Injury | 000 | 3 | NIH | 4/13/2026 | $227,727 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UC2AR081023 | Integrative analysis of high dimensional tissue molecular data to define key biological systems in autoimmune diseases (SBC) | 000 | 5 | NIH | 4/13/2026 | $698,803 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UC2AR081023 | Integrative analysis of high dimensional tissue molecular data to define key biological systems in autoimmune diseases (SBC) | 000 | 5 | NIH | 4/13/2026 | $300,000 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UC2AR081023 | Integrative analysis of high dimensional tissue molecular data to define key biological systems in autoimmune diseases (SBC) | 000 | 5 | NIH | 4/13/2026 | $100,000 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01LM014239 | Identifying and addressing missingness and bias to enhance discovery from multimodal health data | 000 | 4 | NIH | 4/2/2026 | $387,919 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | U01CA268810 | Polygenic risk stratification combined with mpMRI to identify clinically relevant prostate cancer | 001 | 4 | NIH | 4/2/2026 | $583,246 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HD113792 | Mechanics of Vertebrate Embryo Elongation | 001 | 3 | NIH | 4/2/2026 | $63,014 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08AI196234 | A Transposon-based Gene Drive to Combat Antimicrobial Resistance | 000 | 1 | NIH | 4/1/2026 | $171,046 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL168899 | Traffic-Related Ultrafine Particles Disrupt The Resolution Of Lung Inflammation | 000 | 3 | NIH | 3/20/2026 | $690,385 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08AI190123 | Defining the T cell state that sustains chronic allergic disease | 000 | 1 | NIH | 4/1/2026 | $193,600 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01NS123557 | Improved Delivery of Gene Therapies to the Central Nervous System by Focused Ultrasound-Mediated Disruption of the Blood-Brain Barrier | 000 | 5 | NIH | 3/24/2026 | $469,886 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL164380 | Risk Stratification for COPD Exacerbations with CT Analysis and Multidimensional Trajectory Subtyping | 001 | 4 | NIH | 3/25/2026 | $24,369 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01NS142764 | SocialBit2: High-fidelity Mobile Sensing of Social Connection after Stroke | 000 | 1 | NIH | 3/19/2026 | $716,816 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K99CA296755 | Inflammation and Hepatocellular Carcinoma: A Multiomics Approach to Improve Early Detection, Causal Inference, and Lifestyle Based Prevention | 001 | 2 | NIH | 4/16/2026 | $16,588 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R03DE034380 | Medicaid coverage of treatment for periodontal disease and its impact on health outcomes | 001 | 2 | NIH | 4/15/2026 | $18,591 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R03HL183107 | Discovery of rare splicing variants in whole blood and lung | 002 | 1 | NIH | 4/24/2026 | $147,675 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23AR083505 | Integrating multiomic analyses for gene discovery andgenetic diagnosis of Mendelian myopathies | 000 | 3 | NIH | 4/17/2026 | $173,880 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA267479 | MicroRNA control of tumor-promoting inflammation in colon cancer | 001 | 5 | NIH | 4/16/2026 | $38,633 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HD115260 | Composite tissue patterning in mammalian digit tip regeneration | 000 | 3 | NIH | 3/19/2026 | $704,713 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R35GM149229 | Chemical Approaches to Understanding Reversible Lysine Modifications | 000 | 4 | NIH | 4/17/2026 | $447,500 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R03HL183108 | Early Immune Signatures of COPD: Linking Inflammation to Disease Progression | 000 | 1 | NIH | 3/19/2026 | $120,825 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA295683 | Development and optimization of highly effective treatments in patients with head and neck cancer using in situ implantable microdevices | 001 | 2 | NIH | 4/16/2026 | $66,403 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | F32DE035781 | Targeted gene delivery to nociceptors | 000 | 1 | NIH | 3/19/2026 | $80,352 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DC021104 | Genetic Approach to Therapy for DFNA9 | 000 | 4 | NIH | 4/17/2026 | $693,926 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA307291 | Macrophage-directed strategies for BRCA-associated breast cancer | 000 | 1 | NIH | 4/17/2026 | $772,208 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K00CA274651 | Development of Lipid Nanoparticles for B-cell Mediated Immunotherapies | 001 | 4 | NIH | 4/16/2026 | $8,914 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R24OD035402 | A community resource for germline and somatic genetic disease modeling in zebrafish | 001 | 4 | NIH | 4/15/2026 | $210,350 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA124633 | Pathogenesis and Treatment of NUT midline carcinoma | 000 | 19 | NIH | 4/28/2026 | $411,640 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA288535 | Cell surface receptor targeted therapies for brain tumors | 001 | 2 | NIH | 4/16/2026 | $41,171 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01EB034223 | Generating High Quality, High Resolution, Patient-Specific 4D Models of Cerebral Vasculature | 000 | 4 | NIH | 3/19/2026 | $402,750 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R03CA295675 | Mixed Lineage Kinase 2 (MLK2) in tumor angiogenesis | 001 | 2 | NIH | 4/16/2026 | $8,318 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA295752 | DNA damage-related stemness program during BRCA1 breast cancer initiation | 001 | 2 | NIH | 4/16/2026 | $53,089 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI189471 | Lipidomic discovery of physiological CD1 antigens and blockers for human T cells | 000 | 1 | NIH | 4/9/2026 | $893,459 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DK145763 | Dapagliflozin in Active Lupus Nephritis: A Pilot and Feasibility Randomized Trial | 001 | 1 | NIH | 3/30/2026 | $0 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG084017 | Ahead of the Curve: Early detection and monitoring of learning decrements in Alzheimers disease | 000 | 3 | NIH | 4/8/2026 | $850,797 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08NS128329 | Heterogeneity in Toxicity of Oligomeric Amyloid Beta and Neuronal Resilience in Alzheimer Disease | 000 | 5 | NIH | 5/7/2026 | $224,153 |
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