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 | Issue Date FY: 2025 ( Subtotal = $25,342,593 ) (Continued on the next page) |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K01AG080030 | Living beyond cancer: the short- and long-term cognitive effects of breast cancer and its treatment for cancer survivors | 000 | 3 | NIH | 11/22/2024 | $130,950 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL157073 | Role of group 2 innate lymphoid cells in myocardial infarction | 000 | 4 | NIH | 11/26/2024 | $613,929 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI136041 | Eicosanoid Networks in Aspirin Hypersensitivity | 000 | 12 | NIH | 11/18/2024 | $636,768 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08ES034822 | Investigating environmental and gene-environment contributors to Parkinson's disease risk by coupling quantitative environmental exposure data to iPSC modeling | 000 | 3 | NIH | 11/18/2024 | $209,607 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K24AI180296 | Patient-Oriented Research Mentorship and Training in Upper Airway Allergic and Inflammatory Diseases | 000 | 2 | NIH | 11/19/2024 | $174,031 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01MH132632 | Control of ETV1 transcriptional networks in amygdalar astrocytes | 000 | 2 | NIH | 11/20/2024 | $369,631 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08HL163246 | Improving COPD Outcomes: Using Real-World Data to Analyze Treatment Effectiveness, Safety, and Adherence | 000 | 3 | NIH | 11/18/2024 | $165,741 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL167960 | Leveraging machine learning for cardiovascular disease risk prediction and prevention in women with a history of adverse pregnancy outcomes | 000 | 2 | NIH | 11/19/2024 | $741,241 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA241817 | Development of Methods for a Simplified and Reliable Prostate Cancer MRI Exam | 000 | 5 | NIH | 11/19/2024 | $404,800 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08NS136723 | Immune Regulation of the Blood-Brain Barrier | 000 | 1 | NIH | 11/20/2024 | $230,580 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R03AI178363 | Clinically Recognized Congenital Cytomegalovirus Infection and Risk of Long-Term Neurologic and Non-neurologic Complications: Evidence from a Nationwide Cohort | 000 | 2 | NIH | 11/19/2024 | $86,815 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL167905 | miR-130b, angiogenesis, and diabetic critical limb ischemia | 000 | 2 | NIH | 11/8/2024 | $594,287 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA248306 | Mechanism of LSD1 in breast cancer metastasis suppression | 000 | 5 | NIH | 11/6/2024 | $342,494 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R37GM058615 | Mechanisms and Physiology of COPI Transport | 000 | 23 | NIH | 11/15/2024 | $523,574 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UM1AI069412 | Boston HIV CTU | 000 | 19 | NIH | 11/15/2024 | $412,287 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UM1AI069412 | Boston HIV CTU | 000 | 19 | NIH | 11/15/2024 | $1,840,919 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HD099176 | SocialBit: Establishing the accuracy of a wearable sensor to detect social interactions after stroke | 000 | 5 | NIH | 10/31/2024 | $489,949 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI181221 | Interrogating Clonal Repertoire in Drug Hypersensitivity Reactions | 000 | 2 | NIH | 10/31/2024 | $841,591 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R37AI139536 | Neuroimmune interactions regulate development of allergic inflammation | 000 | 7 | NIH | 10/30/2024 | $584,623 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI165382 | KSHV Latency Regulation | 000 | 4 | NIH | 11/1/2024 | $671,213 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI175582 | Skin vaccination and generation of protective lung-tropic memory T cells | 000 | 2 | NIH | 11/4/2024 | $912,384 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K00CA245720 | Genome Integrity Through the Cell Cycle in Homeostasis and Cancer | 000 | 6 | NIH | 11/4/2024 | $105,805 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI179986 | The novel role of MIF-CD74 inflammatory pathway in immune regulation | 000 | 2 | NIH | 11/7/2024 | $408,062 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01ES034079 | Geospatially modeled environmental risk factors for lymphoid malignancies | 000 | 2 | NIH | 10/28/2024 | $690,548 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R13AG092128 | 2024 Biomarkers of Aging Conference | 000 | 1 | NIH | 10/28/2024 | $40,534 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL171141 | Using statistical network methods to elucidate the multi-omic modulators of the effect of maternal vitamin D levels on childhood asthma | 000 | 2 | NIH | 11/25/2024 | $805,344 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01ES025530 | Role of AHR in Dendritic Cells in the Control of CNS Autoimmunity | 000 | 9 | NIH | 11/26/2024 | $372,171 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R38AG085422 | Mentored Research Training in Aging and Surgery (MERITAS) | 000 | 2 | NIH | 11/26/2024 | $363,250 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL130974 | Clinical Genetics and Screening for Pulmonary Fibrosis | 000 | 8 | NIH | 11/30/2024 | $1,155,112 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01MH136503 | Using Neuroimaging to Investigate Mechanism-based Biomarkers of Schizophrenia | 000 | 1 | NIH | 11/29/2024 | $745,741 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL162813 | Uncovering the genetically-driven differential susceptibility to chronic obstructive pulmonary disease and pulmonary fibrosis | 000 | 3 | NIH | 11/29/2024 | $697,156 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01NS136297 | Optimizing Neuromodulation Therapies for Epilepsy: Identifying the Right Patient, Right Place, and Right Time for Stimulation | 000 | 1 | NIH | 11/29/2024 | $690,763 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DK138260 | Development of novel PD1 agonist therapeutic strategies for inflammatory bowel disease | 000 | 2 | NIH | 11/27/2024 | $417,284 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG074899 | Autophagon: an Autophagy-Functionalizing Gene Therapy Tool for Neurodegenerative Diseases | 000 | 5 | NIH | 11/27/2024 | $688,634 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL168899 | Traffic-Related Ultrafine Particles Disrupt The Resolution Of Lung Inflammation | 000 | 2 | NIH | 11/25/2024 | $623,328 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL135142 | Genetic and Genomic Characterization of the Occurrence and Progression of Interstitial Lung Abnormalities | 000 | 6 | NIH | 11/26/2024 | $1,388,686 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI187513 | Rapid point of care Hepatitis C virus detection using a long-lasting luminescent cascade signal amplification | 000 | 1 | NIH | 11/22/2024 | $884,453 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01MH124381 | Brain-based Mechanisms of Emotion Regulation in Aging and Mood Disorders | 000 | 5 | NIH | 11/25/2024 | $684,676 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K25HL157601 | Structural and Funcional Vascular Phenotyping in Smokers with Pulmonary Hypertension using Artificial Intelligence | 000 | 2 | NIH | 11/27/2024 | $187,320 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | AY2AX000058 | DEMOCRATIZE: Driving Equitable Medical Care in Rural America Through Innovative vehicalZE | 000 | 1 | NIH | 11/25/2024 | $4,380,160 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG075509 | Gender-dependent APOE4 regulation of neutrophil-microglia crosstalk in Alzheimer's disease | 000 | 4 | NIH | 11/22/2024 | $664,270 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23DK125672 | Novel Pathways and Therapeutic Targets for Cisplatin-Associated Acute Kidney Injury | 000 | 4 | NIH | 11/22/2024 | $188,266 |
| | 2025 | 2024 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01MH138297 | The SUSTAIN 2 study - SUStained HIV Treatment for Adherence After Interruption in Care | 000 | 1 | NIH | 10/19/2024 | $0 |
| | 2025 | 2024 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | U10CA180821 | Alliance for Clinical Trials in Oncology Operations Center | 000 | 11 | NIH | 10/23/2024 | $0 |
| | 2025 | 2024 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DA049822 | The Comparative Effectiveness and Safety of Pharmacotherapies for the Treatment of Opioid Use Disorder in Pregnancy | 000 | 5 | NIH | 10/10/2024 | $0 |
| | 2025 | 2024 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AR080659 | Immunologic and Clinical Sequelae after COVID-19 in Patients with Systemic Autoimmune Rheumatic Diseases | 000 | 2 | NIH | 11/27/2024 | $0 |
| | 2025 | 2024 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL128658 | Determination of the site of pharyngeal collapse in Obstructive Sleep Apnea patients from snoring sounds | 000 | 7 | NIH | 11/21/2024 | $0 |
| | 2025 | 2024 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | U19AI095219 | Pathophysiologic and Therapeutic Mechanisms of Aspirin Exacerbated Respiratory Disease | 000 | 14 | NIH | 11/20/2024 | $0 |
| | 2025 | 2024 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R35GM128691 | Personalizing Perioperative Preventive Analgesia: Translational Studies Investigating the Biopsychosocial Underpinnings of Enhanced Pain Propensity | 000 | 7 | NIH | 11/6/2024 | $0 |
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