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 | Issue Date FY: 2025 ( Subtotal = $218,617,108 ) (Continued on the next page) |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08HL171877 | Etiology of naturally-occurring anti-ABO antibodies | 000 | 2 | NIH | 3/10/2025 | $168,480 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21AR080849 | Osteoclasts or RANKL: Which is the critical target in treatment of fibrous dysplasia bone lesions? | 000 | 2 | NIH | 2/17/2025 | $174,545 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL163099 | Mechanisms and Modulation of Accelerated Atherosclerosis in Clonal Hematopoiesis | 000 | 4 | NIH | 2/14/2025 | $585,400 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UC2AR081023 | Integrative analysis of high dimensional tissue molecular data to define key biological systems in autoimmune diseases (SBC) | 002 | 4 | NIH | 7/8/2025 | $0 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UC2AR081023 | Integrative analysis of high dimensional tissue molecular data to define key biological systems in autoimmune diseases (SBC) | 002 | 4 | NIH | 7/8/2025 | $0 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08HL177156 | Immuno-Metabolic Regulation of Vascular Dysfunction by CD70 | 000 | 1 | NIH | 2/24/2025 | $167,400 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UC2AR081023 | Integrative analysis of high dimensional tissue molecular data to define key biological systems in autoimmune diseases (SBC) | 001 | 4 | NIH | 6/6/2025 | $0 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UC2AR081023 | Integrative analysis of high dimensional tissue molecular data to define key biological systems in autoimmune diseases (SBC) | 001 | 4 | NIH | 6/6/2025 | $0 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UC2AR081023 | Integrative analysis of high dimensional tissue molecular data to define key biological systems in autoimmune diseases (SBC) | 000 | 4 | NIH | 2/14/2025 | $500,000 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UC2AR081023 | Integrative analysis of high dimensional tissue molecular data to define key biological systems in autoimmune diseases (SBC) | 000 | 4 | NIH | 2/14/2025 | $100,000 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DK137856 | Validation of a novel cerebellar-striatal satiety circuit in human | 001 | 2 | NIH | 7/3/2025 | $74,779 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DK137856 | Validation of a novel cerebellar-striatal satiety circuit in human | 000 | 2 | NIH | 2/18/2025 | $673,005 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DA061199 | A Psilocybin-Sensitive Neuroimmune Circuit Controlling Stress Behaviors | 000 | 2 | NIH | 2/14/2025 | $497,726 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DA061199 | A Psilocybin-Sensitive Neuroimmune Circuit Controlling Stress Behaviors | 001 | 2 | NIH | 4/10/2025 | $55,303 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R00CA256497 | Integrative Prediction of Therapeutic Response in T-cell Lymphoma by Omic and Spatial Modeling | 001 | 5 | NIH | 5/22/2025 | $24,901 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R00CA256497 | Integrative Prediction of Therapeutic Response in T-cell Lymphoma by Omic and Spatial Modeling | 000 | 5 | NIH | 2/14/2025 | $224,099 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AR076973 | Development of enthesopathy in the mouse model of X-linked hypophosphatemia | 001 | 5 | NIH | 6/2/2025 | $26,333 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AR076973 | Development of enthesopathy in the mouse model of X-linked hypophosphatemia | 000 | 5 | NIH | 2/14/2025 | $338,567 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HD101101 | Mechanistic pathways of the effects of human-animal interaction on depression and psychosocial stress | 001 | 5 | NIH | 5/19/2025 | $66,726 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HD101101 | Mechanistic pathways of the effects of human-animal interaction on depression and psychosocial stress | 000 | 5 | NIH | 2/19/2025 | $600,539 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01MD016178 | Social networks and risk of delayed arrival to the hospital during stroke | 000 | 4 | NIH | 2/21/2025 | $663,585 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01NS119476 | Next Generation Gene Therapy for Refractory Pain | 000 | 4 | NIH | 3/4/2025 | $634,215 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG080429 | Leveraging Longitudinal Data and Informatics Technology to Understand the Role of Bilingualism in Cognitive Resilience, Aging and Dementia | 001 | 3 | NIH | 6/17/2025 | $109,693 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG080429 | Leveraging Longitudinal Data and Informatics Technology to Understand the Role of Bilingualism in Cognitive Resilience, Aging and Dementia | 000 | 3 | NIH | 3/6/2025 | $1,234,055 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01ES036206 | Per- and polyfluoroalkyl substances, apolipoproteins, and risk of coronary heart disease | 000 | 2 | NIH | 2/14/2025 | $702,691 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AR077132 | Suturable bioprinted vascularized muscle constructs for treatment of skeletal muscle loss | 001 | 5 | NIH | 5/22/2025 | $35,284 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AR077132 | Suturable bioprinted vascularized muscle constructs for treatment of skeletal muscle loss | 000 | 5 | NIH | 2/14/2025 | $453,645 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA235134 | Adaptive Percutaneous Prostate Interventions using Sensorized Needle | 002 | 5 | NIH | 5/22/2025 | $61,989 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA235134 | Adaptive Percutaneous Prostate Interventions using Sensorized Needle | 001 | 5 | NIH | 2/13/2025 | $557,907 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R00NS114111 | Molecular Control of Astrocytes in CNS Inflammation | 001 | 5 | NIH | 3/20/2025 | -$24,899 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R00NS114111 | Molecular Control of Astrocytes in CNS Inflammation | 000 | 5 | NIH | 1/27/2025 | $249,000 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R03DE034380 | Medicaid coverage of treatment for periodontal disease and its impact on health outcomes | 000 | 1 | NIH | 1/27/2025 | $185,918 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08EB034299 | Rapid Anatomic and Quantitative MR Imaging of the Skull Base and Face | 000 | 2 | NIH | 1/27/2025 | $191,138 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08DK131321 | IL1 as a Driver of Mucosal Immune Dysregulation in Inflammatory Bowel Disease | 000 | 4 | NIH | 2/19/2025 | $168,400 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DK136617 | Urine levels of Glycated CD59 for screening and diagnosis of pregnancy-induced glucose intolerance | 000 | 2 | NIH | 2/17/2025 | $647,442 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R35GM153468 | Decoding the Molecular Mechanisms Governing Regulation and Reprogramming of Cellular Identity | 001 | 2 | NIH | 1/28/2025 | $403,650 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG084531 | Combination Therapy with Semaglutide and Anti-Amyloid Antibodies for Alzheimers Disease | 000 | 2 | NIH | 1/28/2025 | $765,619 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R35GM153468 | Decoding the Molecular Mechanisms Governing Regulation and Reprogramming of Cellular Identity | 003 | 2 | NIH | 4/25/2025 | $289,477 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K24HL136852 | Mentored Patient-Oriented Research for Preventing ASCVD Events | 002 | 8 | NIH | 5/12/2025 | $126,184 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23HL159279 | (Administrative Supplement) Cardiac Perfusion, Structure, and Function across the Primary Aldosteronism Spectrum | 000 | 4 | NIH | 2/28/2025 | $192,896 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23HL159279 | (Administrative Supplement) Cardiac Perfusion, Structure, and Function across the Primary Aldosteronism Spectrum | 001 | 4 | NIH | 4/15/2025 | $75,460 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG087356 | Identification of brain metabolomic profiles associated with dementia | 001 | 2 | NIH | 6/9/2025 | $67,443 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG087356 | Identification of brain metabolomic profiles associated with dementia | 000 | 2 | NIH | 3/7/2025 | $758,747 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23AR080203 | Multi-omic Studies of Local and Systemic Immune Dysregulation in Rosacea | 000 | 4 | NIH | 3/13/2025 | $169,884 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI156084 | IRI, innate immunity and transplant rejection | 000 | 5 | NIH | 2/13/2025 | $434,700 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01NS121096 | Gene Edited and Engineered Tumor Cell Therapeutics for Cancer | 000 | 5 | NIH | 3/14/2025 | $373,424 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA235589 | Lymph Node Quantification System for Multisite Clinical Trials | 001 | 6 | NIH | 3/10/2025 | $703,707 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R03OD039974 | Accurate, fast, and distributed atlas-scale integration of scRNAseq data | 000 | 1 | NIH | 6/10/2025 | $1 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R03OD039974 | Accurate, fast, and distributed atlas-scale integration of scRNAseq data | 000 | 1 | NIH | 6/10/2025 | $357,999 |
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