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 | Issue Date FY: 2025 ( Subtotal = $202,186,340 ) (Continued on the next page) |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG080429 | Leveraging Longitudinal Data and Informatics Technology to Understand the Role of Bilingualism in Cognitive Resilience, Aging and Dementia | 000 | 3 | NIH | 3/6/2025 | $1,234,055 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01NS119476 | Next Generation Gene Therapy for Refractory Pain | 000 | 4 | NIH | 3/4/2025 | $634,215 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HD101101 | Mechanistic pathways of the effects of human-animal interaction on depression and psychosocial stress | 001 | 5 | NIH | 5/19/2025 | $66,726 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HD101101 | Mechanistic pathways of the effects of human-animal interaction on depression and psychosocial stress | 000 | 5 | NIH | 2/19/2025 | $600,539 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01MD016178 | Social networks and risk of delayed arrival to the hospital during stroke | 000 | 4 | NIH | 2/21/2025 | $663,585 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08HL157725 | High-dimensional single-cell mapping to define immune signatures of cytomegalovirus-associated rejection in cardiac transplantation | 002 | 5 | NIH | 2/20/2025 | $169,560 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R00NS114111 | Molecular Control of Astrocytes in CNS Inflammation | 001 | 5 | NIH | 3/20/2025 | -$24,899 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R00NS114111 | Molecular Control of Astrocytes in CNS Inflammation | 000 | 5 | NIH | 1/27/2025 | $249,000 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R03DE034380 | Medicaid coverage of treatment for periodontal disease and its impact on health outcomes | 000 | 1 | NIH | 1/27/2025 | $185,918 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08EB034299 | Rapid Anatomic and Quantitative MR Imaging of the Skull Base and Face | 000 | 2 | NIH | 1/27/2025 | $191,138 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K24HL136852 | Mentored Patient-Oriented Research for Preventing ASCVD Events | 002 | 8 | NIH | 5/12/2025 | $126,184 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG084531 | Combination Therapy with Semaglutide and Anti-Amyloid Antibodies for Alzheimers Disease | 000 | 2 | NIH | 1/28/2025 | $765,619 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R35GM153468 | Decoding the Molecular Mechanisms Governing Regulation and Reprogramming of Cellular Identity | 003 | 2 | NIH | 4/25/2025 | $289,477 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R35GM153468 | Decoding the Molecular Mechanisms Governing Regulation and Reprogramming of Cellular Identity | 001 | 2 | NIH | 1/28/2025 | $403,650 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01EB035679 | An AI-Assisted Strategy for Monitoring Pulmonary Congestion in Acute Heart Failure Patients in Emergency Settings | 000 | 1 | NIH | 1/30/2025 | $608,944 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01MD016910 | Disasters and Hospital Systems Serving Health Disparity Populations: Identifying the Long Term effects of the COVID-19 Pandemic to Mitigate Future Challenges | 001 | 3 | NIH | 5/27/2025 | $0 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01MD016910 | Disasters and Hospital Systems Serving Health Disparity Populations: Identifying the Long Term effects of the COVID-19 Pandemic to Mitigate Future Challenges | 000 | 3 | NIH | 12/22/2024 | $614,364 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UM1AI069412 | Boston HIV CTU | 001 | 19 | NIH | 4/24/2025 | $412,287 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UM1AI069412 | Boston HIV CTU | 001 | 19 | NIH | 4/24/2025 | $1,840,918 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UM1AI069412 | Boston HIV CTU | 000 | 19 | NIH | 11/15/2024 | $412,287 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UM1AI069412 | Boston HIV CTU | 000 | 19 | NIH | 11/15/2024 | $1,840,919 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01MH132632 | Control of ETV1 transcriptional networks in amygdalar astrocytes | 000 | 2 | NIH | 11/20/2024 | $369,631 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R35GM152063 | Epigenetic regulation of transcriptional programming | 001 | 2 | NIH | 5/26/2025 | $680,200 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DK135667 | Pathobiology of autoimmune-mediated diffuse podocytopathy | 000 | 2 | NIH | 6/20/2025 | $708,681 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21AI181873 | Systematic CRISPR Analysis of EBV Lymphoma Resistance Pathways to Natural Killer Cell Lysis | 000 | 2 | NIH | 6/3/2025 | $268,500 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI179986 | The novel role of MIF-CD74 inflammatory pathway in immune regulation | 000 | 2 | NIH | 11/7/2024 | $408,062 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08DE030216 | Development of an artificial intelligence-driven, imaging-based platform for pretreatment identification of extranodal extension in head and neck cancer | 000 | 5 | NIH | 12/31/2024 | $168,240 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI175582 | Skin vaccination and generation of protective lung-tropic memory T cells | 000 | 2 | NIH | 11/4/2024 | $912,384 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23HL159279 | (Administrative Supplement) Cardiac Perfusion, Structure, and Function across the Primary Aldosteronism Spectrum | 000 | 4 | NIH | 2/28/2025 | $192,896 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23HL159279 | (Administrative Supplement) Cardiac Perfusion, Structure, and Function across the Primary Aldosteronism Spectrum | 001 | 4 | NIH | 4/15/2025 | $75,460 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA235589 | Lymph Node Quantification System for Multisite Clinical Trials | 001 | 6 | NIH | 3/10/2025 | $703,707 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG080992 | Role of a novel risk loci HAVCR2 of late-onset Alzheimer's disease in the regulation of microglial response in neurodegeneration | 001 | 3 | NIH | 6/17/2025 | $66,393 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG080992 | Role of a novel risk loci HAVCR2 of late-onset Alzheimer's disease in the regulation of microglial response in neurodegeneration | 000 | 3 | NIH | 3/6/2025 | $746,921 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R03OD039974 | Accurate, fast, and distributed atlas-scale integration of scRNAseq data | 000 | 1 | NIH | 6/10/2025 | $1 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R03OD039974 | Accurate, fast, and distributed atlas-scale integration of scRNAseq data | 000 | 1 | NIH | 6/10/2025 | $357,999 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DK138036 | Novel approaches to improve comparative effectiveness research of medical and surgical weight reduction strategies in clinical practice | 001 | 2 | NIH | 6/26/2025 | $77,255 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DK138036 | Novel approaches to improve comparative effectiveness research of medical and surgical weight reduction strategies in clinical practice | 000 | 2 | NIH | 3/5/2025 | $695,317 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL168199 | Identifying Subtypes of COPD Using Metabolomic and Genomic Approaches | 000 | 2 | NIH | 3/19/2025 | $627,879 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | U01AG086168 | Understanding Interorgan Communication Through Heterochronic Organ Transplantation | 000 | 2 | NIH | 3/6/2025 | $617,098 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | U01AG086168 | Understanding Interorgan Communication Through Heterochronic Organ Transplantation | 001 | 2 | NIH | 6/9/2025 | $54,852 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AR080194 | New approaches to safety monitoring of novel systemic treatments for atopic dermatitis in clinical practice and underrepresented populations | 001 | 4 | NIH | 6/11/2025 | $44,504 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AR080194 | New approaches to safety monitoring of novel systemic treatments for atopic dermatitis in clinical practice and underrepresented populations | 000 | 4 | NIH | 2/19/2025 | $572,186 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23NS136767 | Predicting Dependency after Traumatic Brain Injury | 000 | 2 | NIH | 3/20/2025 | $227,707 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL170000 | Role of CLCA1 as a MIF decoy inhibitor in abdominal aortic aneurysms | 000 | 2 | NIH | 3/10/2025 | $642,975 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL065095 | Regulators of immune complex mediated neutrophil antigen presentation | 000 | 26 | NIH | 3/11/2025 | $676,617 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DC020965 | Naturalistic Neuroimaging for Presurgical Language Mapping | 002 | 3 | NIH | 5/30/2025 | $62,362 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DC020965 | Naturalistic Neuroimaging for Presurgical Language Mapping | 000 | 3 | NIH | 2/25/2025 | $561,270 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08HL171877 | Etiology of naturally-occurring anti-ABO antibodies | 000 | 2 | NIH | 3/10/2025 | $168,480 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL162102 | Menstrual-phase-dependent differences in response to chronic variable sleep loss | 001 | 4 | NIH | 4/16/2025 | $802,786 |
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