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 | Issue Date FY: 2025 ( Subtotal = $411,024,921 ) (Continued on the next page) |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | T32HL176440 | Training Program in Patient-Oriented Research in Cardiovascular Endocrinology | 001 | 1 | NIH | 9/3/2025 | -$201,426 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | F32HL178207 | Innovative implementation of artificial intelligence techniques for enhanced management of aortic abdominal aneurysms | 001 | 1 | NIH | 8/12/2025 | $0 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | F32HL178207 | Innovative implementation of artificial intelligence techniques for enhanced management of aortic abdominal aneurysms | 000 | 1 | NIH | 8/12/2025 | $75,520 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | T32HL176440 | Training Program in Patient-Oriented Research in Cardiovascular Endocrinology | 001 | 1 | NIH | 9/3/2025 | $201,426 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | T32HL176440 | Training Program in Patient-Oriented Research in Cardiovascular Endocrinology | 000 | 1 | NIH | 8/28/2025 | $201,426 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21HL181694 | Mathematical Modelling of Peripheral Metabolic Circadian Rhythms: Implications for Shift Work and Jetlag Management | 000 | 1 | NIH | 8/25/2025 | $281,560 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23AT013401 | Acupoint sensitization in inflammatory bowel disease | 000 | 1 | NIH | 8/26/2025 | $145,359 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | U01AG086168 | Understanding Interorgan Communication Through Heterochronic Organ Transplantation | 001 | 2 | NIH | 6/9/2025 | $54,852 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R33MH131043 | Mobile application for early detection and intervention to reduce psychological distress in informal family caregivers of community dwelling adults with chronic disorders in Thailand | 000 | 3 | NIH | 7/31/2025 | $173,865 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | U01AG086168 | Understanding Interorgan Communication Through Heterochronic Organ Transplantation | 000 | 2 | NIH | 3/6/2025 | $617,098 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01EB036996 | Trackerless Surgical Navigation for Dynamic Environments in Minimally Invasive Liver Surgery | 000 | 1 | NIH | 8/1/2025 | $1,554,122 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R00MH131850 | Towards Developing Biomarkers for Premature Aging in Schizophrenia | 001 | 3 | NIH | 8/18/2025 | -$249,000 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R00MH131850 | Towards Developing Biomarkers for Premature Aging in Schizophrenia | 001 | 3 | NIH | 8/18/2025 | $249,000 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K24HL175495 | Volume And Patient-Oriented Research in Chronic Kidney Disease (VAPOR-CKD) | 000 | 1 | NIH | 8/27/2025 | $131,886 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG080992 | Role of a novel risk loci HAVCR2 of late-onset Alzheimer's disease in the regulation of microglial response in neurodegeneration | 001 | 3 | NIH | 6/17/2025 | $66,393 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R00MH131850 | Towards Developing Biomarkers for Premature Aging in Schizophrenia | 000 | 3 | NIH | 8/12/2025 | $249,000 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23HD118179 | Nourishing Growing Brains: Maternal Micronutrient Supplementation during Lactation, Human Milk B-Complex Vitamins, and Infant Neurodevelopment | 000 | 1 | NIH | 8/1/2025 | $167,400 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R03OD039974 | Accurate, fast, and distributed atlas-scale integration of scRNAseq data | 000 | 1 | NIH | 6/10/2025 | $357,999 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG080992 | Role of a novel risk loci HAVCR2 of late-onset Alzheimer's disease in the regulation of microglial response in neurodegeneration | 000 | 3 | NIH | 3/6/2025 | $746,921 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL176714 | Leveraging research and clinical cohorts to improve Obstructive Sleep Apnea subtyping | 000 | 1 | NIH | 8/22/2025 | $818,279 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UG3MH141096 | Dynamic Decision Support Tools for Precision Treatment-Resistant Depression Care | 000 | 1 | NIH | 8/29/2025 | $1,688,034 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R33MH131043 | Mobile application for early detection and intervention to reduce psychological distress in informal family caregivers of community dwelling adults with chronic disorders in Thailand | 002 | 3 | NIH | 9/9/2025 | $7,200 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R61NS138810 | Optimization of New Drugs for the Treatment of Essential Tremor | 000 | 1 | NIH | 7/31/2025 | $864,552 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R33MH131043 | Mobile application for early detection and intervention to reduce psychological distress in informal family caregivers of community dwelling adults with chronic disorders in Thailand | 001 | 3 | NIH | 8/6/2025 | $100,800 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R03OD039974 | Accurate, fast, and distributed atlas-scale integration of scRNAseq data | 000 | 1 | NIH | 6/10/2025 | $1 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21TW012945 | Rapid Emergency Skills for Prehospital Optimization, Notification, and Delivery (RESPOND-Guatemala): A comprehensive mHealth program for emergency prehospital skills and triage notification | 002 | 1 | NIH | 9/15/2025 | $2,322 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL176637 | Endothelial Inflammation, Src Kinase Dysregulation, and Fibrosis in Early Pulmonary Arterial Hypertension | 000 | 1 | NIH | 9/8/2025 | $800,962 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R56HL179741 | FcgR-activated neutrophil regulation of T cells in nephritis and vasculitis | 000 | 1 | NIH | 9/8/2025 | $300,000 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21AG091064 | Determining if Tregs are Dysfunctional in Alzheimer's Diseases | 000 | 1 | NIH | 9/12/2025 | $492,250 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | F32GM159396 | Development of small molecule inhibitors of the E3 ligase NEDD4 | 000 | 1 | NIH | 9/11/2025 | $75,520 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21TW012945 | Rapid Emergency Skills for Prehospital Optimization, Notification, and Delivery (RESPOND-Guatemala): A comprehensive mHealth program for emergency prehospital skills and triage notification | 001 | 1 | NIH | 9/14/2025 | $57,309 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | F32GM159396 | Development of small molecule inhibitors of the E3 ligase NEDD4 | 001 | 1 | NIH | 9/11/2025 | $0 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K99AI191990 | Ultra-long-acting delivery for the prevention and treatment of HIV/AIDS | 000 | 1 | NIH | 9/3/2025 | $135,540 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21TW012945 | Rapid Emergency Skills for Prehospital Optimization, Notification, and Delivery (RESPOND-Guatemala): A comprehensive mHealth program for emergency prehospital skills and triage notification | 000 | 1 | NIH | 9/12/2025 | $146,501 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | OT2OD040029 | Feasibility of Genomic Newborn Screening Through Public Health Laboratories | 000 | 1 | NIH | 9/4/2025 | $14,399,393 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R03DK144241 | Incident Hemodialysis Electrolyte Analysis and Rhythm Trends (IHEART) | 000 | 1 | NIH | 9/8/2025 | $268,500 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K24HL179901 | Linking Mechanism to Outcome in Airway Inflammation and Remodeling | 000 | 1 | NIH | 9/12/2025 | $133,221 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08AI194971 | Expanded evaluation of the role of antibody-dependent innate effector function in TB disease progression in HIV co-infected individuals | 000 | 1 | NIH | 9/11/2025 | $194,400 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DK142791 | Targeting LIGHT for treatment of glomerulonephritis | 000 | 1 | NIH | 8/29/2025 | $2,466,907 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL168067 | Role of ventilatory drive in obstructive sleep apnea: An avenue for precision intervention | 001 | 3 | NIH | 8/12/2025 | $894,263 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01LM014667 | Developing large language models for drug safety and effectiveness causal analysis | 000 | 1 | NIH | 7/31/2025 | $402,750 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | P50CA165962 | Targeted Therapies for Glioma | 001 | 10 | NIH | 3/19/2025 | $2,442,975 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UG3AI190114 | Harnessing translational research to advance understanding and clinical care in antibiotic allergy | 000 | 1 | NIH | 7/23/2025 | $443,527 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R35GM157032 | Molecular Mechanisms of Hormone-Mediated Sex Differences in Wound Healing | 002 | 2 | NIH | 8/27/2025 | $442,444 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL175295 | Beyond BMI: Role of Body Composition, Coronary Microvascular Dysfunction and HFpEF in Characterizing Cardiometabolic Disease Phenotypes | 000 | 1 | NIH | 8/15/2025 | $784,362 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA296008 | Magnetic Resonance Fingerprinting of Glutamate Metabolism for Guiding Glioma Cancer Care | 000 | 1 | NIH | 8/14/2025 | $3,155,815 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K01HL177168 | Place-Based Factors Contributing to Sleep Health Disparities in the United States | 000 | 1 | NIH | 9/18/2025 | $177,385 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | U01AI186972 | Harnessing Trained Immunity as a Radiation Medical Countermeasure | 000 | 1 | NIH | 9/24/2025 | $586,619 |
| 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL180621 | Characterization of lung interstitial neutrophils | 000 | 1 | NIH | 8/21/2025 | $710,302 |
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