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 | Issue Date FY: 2026 ( Subtotal = $4,305,716 ) |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI175582 | Skin vaccination and generation of protective lung-tropic memory T cells | 000 | 3 | NIH | 11/26/2025 | $940,602 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01MH132632 | Control of ETV1 transcriptional networks in amygdalar astrocytes | 000 | 3 | NIH | 12/3/2025 | $434,860 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI179807 | Harnessing commensal redox metabolism in infection prevention | 000 | 3 | NIH | 12/4/2025 | $849,858 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R37AI139536 | Neuroimmune interactions regulate development of allergic inflammation | 000 | 8 | NIH | 12/2/2025 | $602,703 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI187513 | Rapid point of care Hepatitis C virus detection using a long-lasting luminescent cascade signal amplification | 000 | 2 | NIH | 12/4/2025 | $875,816 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI136041 | Eicosanoid Networks in Aspirin Hypersensitivity | 000 | 13 | NIH | 12/3/2025 | $656,461 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | U54AG062322 | Center for Stress and Neural Regulation of Reproductive Aging Health Outcomes | 000 | 6 | NIH | 11/26/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | U01AI186972 | Harnessing Trained Immunity as a Radiation Medical Countermeasure | 000 | 1 | NIH | 11/26/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | U01AG089040 | Development, Validation, and Harmonization of Methods for Collection and Measurement of NAD+ and Related Metabolites: Application to a Randomized Trial of Patients Undergoing Coronary Artery Bypass | 000 | 2 | NIH | 12/3/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23HL171893 | Interplay of Inflammation, Angiogenesis, and Coronary Microvascular Perfusion in Advanced Kidney Disease | 000 | 1 | NIH | 12/3/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K01DA061975 | Dynamic Treatment Regimes for Personalized Opioid Use Disorder Care | 000 | 1 | NIH | 12/3/2025 | $0 |
| | 2026 | 2024 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL153004 | Aldosterone, the Mineralocorticoid Receptor, and Cardiovascular Disease in Obesity | 000 | 5 | NIH | 12/1/2025 | $0 |
| | 2026 | 2024 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA074305 | Chemical Approaches to Cell Signaling Enzymes | 000 | 30 | NIH | 11/26/2025 | $0 |
| | 2026 | 2024 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG064223 | Role of rare damaging mutations in aging | 000 | 5 | NIH | 11/25/2025 | -$25,688 |
| | 2026 | 2024 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23MH120324 | Toward optimizing digital mental health interventions: A clinical trial aimed at understanding what drives patient engagement. | 000 | 5 | NIH | 12/4/2025 | $0 |
| | 2026 | 2024 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K99MH131850 | Towards Developing Biomarkers for Premature Aging in Schizophrenia | 000 | 2 | NIH | 11/26/2025 | $0 |
| | 2026 | 2023 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UM1CA186107 | Long Term Multidisciplinary Study of Cancer in Women: The Nurses Health Study | 000 | 10 | NIH | 12/4/2025 | -$11 |
| | 2026 | 2023 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DE028336 | Long Term Oral Health Outcomes in the Chronic GVHD Consortium | 000 | 5 | NIH | 12/4/2025 | $0 |
| | 2026 | 2022 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21NS127299 | Cell-specific Functional and Transcriptomic Analysis of Plasticity Pathways in MECP2-Duplication Syndrome | 000 | 1 | NIH | 11/25/2025 | $0 |
| | 2026 | 2021 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01MH113256 | Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar Disorder | 000 | 5 | NIH | 11/20/2025 | -$28,885 |
|
| Issue Date FY: 2025 ( Subtotal = $411,024,921 ) (Continued on the next page) |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AR080194 | New approaches to safety monitoring of novel systemic treatments for atopic dermatitis in clinical practice and underrepresented populations | 000 | 4 | NIH | 2/19/2025 | $572,186 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08HL177156 | Immuno-Metabolic Regulation of Vascular Dysfunction by CD70 | 000 | 1 | NIH | 2/24/2025 | $167,400 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R00CA256497 | Integrative Prediction of Therapeutic Response in T-cell Lymphoma by Omic and Spatial Modeling | 001 | 5 | NIH | 5/22/2025 | $24,901 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R00CA256497 | Integrative Prediction of Therapeutic Response in T-cell Lymphoma by Omic and Spatial Modeling | 000 | 5 | NIH | 2/14/2025 | $224,099 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UC2AR081023 | Integrative analysis of high dimensional tissue molecular data to define key biological systems in autoimmune diseases (SBC) | 002 | 4 | NIH | 7/8/2025 | $0 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AR076973 | Development of enthesopathy in the mouse model of X-linked hypophosphatemia | 001 | 5 | NIH | 6/2/2025 | $26,333 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UC2AR081023 | Integrative analysis of high dimensional tissue molecular data to define key biological systems in autoimmune diseases (SBC) | 002 | 4 | NIH | 7/8/2025 | $0 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AR076973 | Development of enthesopathy in the mouse model of X-linked hypophosphatemia | 000 | 5 | NIH | 2/14/2025 | $338,567 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DK137856 | Validation of a novel cerebellar-striatal satiety circuit in human | 001 | 2 | NIH | 7/3/2025 | $74,779 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UC2AR081023 | Integrative analysis of high dimensional tissue molecular data to define key biological systems in autoimmune diseases (SBC) | 001 | 4 | NIH | 6/6/2025 | $0 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DK137856 | Validation of a novel cerebellar-striatal satiety circuit in human | 000 | 2 | NIH | 2/18/2025 | $673,005 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K01HL177168 | Place-Based Factors Contributing to Sleep Health Disparities in the United States | 000 | 1 | NIH | 9/18/2025 | $177,385 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AR085629 | Discovering and characterizing the germline mechanisms of cutaneous immune-related adverse events (cirAE) | 000 | 1 | NIH | 9/4/2025 | $746,572 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R34AT013522 | Harmonized Healing: Personalized Music Interventions to Address Chronic Pain in People Living with HIV | 000 | 1 | NIH | 9/4/2025 | $269,468 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL172907 | Optimizing Cardiovascular Care and Promoting Excellent Health Outcomes for Adults with Diabetes across settings | 000 | 1 | NIH | 9/1/2025 | $763,858 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K76AG095036 | Evaluating the effect of a new Medicare dental benefit on the health of older adults | 000 | 1 | NIH | 9/10/2025 | $242,196 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL176637 | Endothelial Inflammation, Src Kinase Dysregulation, and Fibrosis in Early Pulmonary Arterial Hypertension | 000 | 1 | NIH | 9/8/2025 | $800,962 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23AI185318 | Defining vaccine immunogenicity and adoptive transfer in hematopoietic stem cell transplant recipients | 000 | 1 | NIH | 9/15/2025 | $194,400 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23AA032563 | A digital pill system to measure and support acamprosate adherence in individuals with alcohol associated liver disease | 000 | 1 | NIH | 9/16/2025 | $194,062 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | OT2OD040029 | Feasibility of Genomic Newborn Screening Through Public Health Laboratories | 000 | 1 | NIH | 9/4/2025 | $14,399,393 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG095009 | The Ante-Amyloid Treatment of Alzheimer's disease (A3) Trial and Alzheimer Plasma EXtension (APEX) Study | 000 | 1 | NIH | 8/29/2025 | $6,467,513 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG088141 | Nicotinamide Adenine Dinucleotide Augmentation to Prevent or Reverse the Progression of Alzheimer's Disease in People with Down Syndrome | 000 | 1 | NIH | 9/8/2025 | $801,359 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K99CA293266 | Elucidating pathways underlying the association of contraception use with ovarian cancers through metabolic profiling | 000 | 1 | NIH | 9/11/2025 | $155,605 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | F32GM159396 | Development of small molecule inhibitors of the E3 ligase NEDD4 | 000 | 1 | NIH | 9/11/2025 | $75,520 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21TW012945 | Rapid Emergency Skills for Prehospital Optimization, Notification, and Delivery (RESPOND-Guatemala): A comprehensive mHealth program for emergency prehospital skills and triage notification | 001 | 1 | NIH | 9/14/2025 | $57,309 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | F32GM159396 | Development of small molecule inhibitors of the E3 ligase NEDD4 | 001 | 1 | NIH | 9/11/2025 | $0 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K99AI191990 | Ultra-long-acting delivery for the prevention and treatment of HIV/AIDS | 000 | 1 | NIH | 9/3/2025 | $135,540 |
| | 2025 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21TW012945 | Rapid Emergency Skills for Prehospital Optimization, Notification, and Delivery (RESPOND-Guatemala): A comprehensive mHealth program for emergency prehospital skills and triage notification | 000 | 1 | NIH | 9/12/2025 | $146,501 |
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