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 | Issue Date FY: 2026 ( Subtotal = $373,285,798 ) (Continued on the next page) |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DC023537 | Hormonal and Multi-Omic Factors Associated with Tinnitus Incidence and Remission in Women | 000 | 1 | NIH | 8/20/2026 | $225,000 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R00HL165024 | Using genomic modifiers to mechanistically link clonal hematopoiesis of indeterminate potential penetrance to coronary artery disease | 000 | 3 | NIH | 3/10/2026 | $249,000 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01NS142764 | SocialBit2: High-fidelity Mobile Sensing of Social Connection after Stroke | 000 | 1 | NIH | 3/19/2026 | $716,816 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL176637 | Endothelial Inflammation, Src Kinase Dysregulation, and Fibrosis in Early Pulmonary Arterial Hypertension | 000 | 2 | NIH | 7/14/2026 | $739,659 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | F32DE035781 | Targeted gene delivery to nociceptors | 002 | 1 | NIH | 9/16/2026 | $0 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DK145733 | Metabolomics-Driven Insights into Ultra-Processed Foods: Identifying High-Risk UPF Subtypes for T2D Prevention | 000 | 1 | NIH | 8/31/2026 | $894,984 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | F32DE035781 | Targeted gene delivery to nociceptors | 001 | 1 | NIH | 3/19/2026 | $0 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | F32DE035781 | Targeted gene delivery to nociceptors | 000 | 1 | NIH | 3/19/2026 | $80,352 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | U01AI201044 | Allergen and damage sensing by chemosensory tuft cells in the airway | 000 | 1 | NIH | 7/3/2026 | $564,396 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R03HL183108 | Early Immune Signatures of COPD: Linking Inflammation to Disease Progression | 000 | 1 | NIH | 3/19/2026 | $120,825 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DE036397 | Targeted Gene Delivery to Trigeminal Nociceptors | 000 | 1 | NIH | 9/1/2026 | $694,824 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R37AI150396 | HIV Reservoir Ecology of Viral Remission (PTC) | 000 | 7 | NIH | 8/25/2026 | $867,687 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21TW012945 | Rapid Emergency Skills for Prehospital Optimization, Notification, and Delivery (RESPOND-Guatemala): A comprehensive mHealth program for emergency prehospital skills and triage notification | 002 | 2 | NIH | 8/26/2026 | $1,944 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21TW012945 | Rapid Emergency Skills for Prehospital Optimization, Notification, and Delivery (RESPOND-Guatemala): A comprehensive mHealth program for emergency prehospital skills and triage notification | 001 | 2 | NIH | 8/26/2026 | $95,473 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K99AI191990 | Ultra-long-acting delivery for the prevention and treatment of HIV/AIDS | 000 | 2 | NIH | 9/4/2026 | $135,540 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21TW012945 | Rapid Emergency Skills for Prehospital Optimization, Notification, and Delivery (RESPOND-Guatemala): A comprehensive mHealth program for emergency prehospital skills and triage notification | 000 | 2 | NIH | 8/14/2026 | $63,826 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | F32GM159396 | Development of small molecule inhibitors of the E3 ligase NEDD4 | 000 | 2 | NIH | 8/21/2026 | $79,348 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K24HL179901 | Linking Mechanism to Outcome in Airway Inflammation and Remodeling | 000 | 2 | NIH | 8/25/2026 | $133,221 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23AR087540 | Quantitative chest imaging and serum proteomics in patients with systemic autoimmune rheumatic disease-associated interstitial lung disease | 000 | 1 | NIH | 8/31/2026 | $172,470 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG093025 | Health Care Contact Days: Assessing Key Perspectives, the Role of Health Systems, and Impact on Patient Outcomes | 000 | 1 | NIH | 8/31/2026 | $943,368 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG102399 | Advance Care Planning for Older Individuals with Down Syndrome Experiencing Early Onset and Accelerated Dementia: A Mechanistic Evaluation | 000 | 1 | NIH | 8/31/2026 | $889,734 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R37AI150396 | HIV Reservoir Ecology of Viral Remission (PTC) | 003 | 7 | NIH | 9/4/2026 | $0 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R37AI150396 | HIV Reservoir Ecology of Viral Remission (PTC) | 001 | 7 | NIH | 8/31/2026 | $0 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21HL184189 | Integrative Single-Cell Analysis of Aging-Associated Changes in Human Hematopoietic Stem Cell Heterogeneity | 000 | 1 | NIH | 3/9/2026 | $134,250 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI189471 | Lipidomic discovery of physiological CD1 antigens and blockers for human T cells | 000 | 1 | NIH | 4/9/2026 | $893,459 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21HL184189 | Integrative Single-Cell Analysis of Aging-Associated Changes in Human Hematopoietic Stem Cell Heterogeneity | 001 | 1 | NIH | 4/20/2026 | $134,250 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K01HL186417 | Understanding the Role of the X Chromosome in COPD through Integrated Multi-Omic Approaches | 000 | 1 | NIH | 5/12/2026 | $177,355 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG088141 | Nicotinamide Adenine Dinucleotide Augmentation to Prevent or Reverse the Progression of Alzheimer's Disease in People with Down Syndrome | 002 | 2 | NIH | 9/9/2026 | $801,611 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R13AT013876 | The Science of Tai Chi & Qigong as Whole Person Health: Deepening Our Physiological Understanding of the Mind-Body Connection | 000 | 1 | NIH | 5/7/2026 | $30,000 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R13AT013876 | The Science of Tai Chi & Qigong as Whole Person Health: Deepening Our Physiological Understanding of the Mind-Body Connection | 000 | 1 | NIH | 5/7/2026 | $15,000 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL172907 | Optimizing Cardiovascular Care and Promoting Excellent Health Outcomes for Adults with Diabetes across settings | 000 | 2 | NIH | 9/3/2026 | $710,349 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG095009 | The Ante-Amyloid Treatment of Alzheimer's disease (A3) Trial and Alzheimer Plasma EXtension (APEX) Study | 000 | 2 | NIH | 8/19/2026 | $6,451,513 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA307291 | Macrophage-directed strategies for BRCA-associated breast cancer | 000 | 1 | NIH | 4/17/2026 | $772,208 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K99DE034830 | Investigation of Key Nicotinamide Adenine Dinucleotide Metabolism Pathway Roles in Support of Epstein-Barr Virus Replication | 000 | 1 | NIH | 2/27/2026 | $135,000 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DK147058 | Real-World Evaluation of Continuous Glucose Monitoring in Older Adults With Type 2 Diabetes: A Multisite Study of Structures, Processes, and Outcome | 000 | 1 | NIH | 5/12/2026 | $891,382 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23AI185318 | Defining vaccine immunogenicity and adoptive transfer in hematopoietic stem cell transplant recipients | 000 | 2 | NIH | 8/6/2026 | $194,400 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21AI196527 | AI-guided Intestinal stem cell activation for mucosal restoration in ulcerative colitis | 000 | 1 | NIH | 2/18/2026 | $479,610 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K76AG095036 | Evaluating the effect of a new Medicare dental benefit on the health of older adults | 001 | 2 | NIH | 8/17/2026 | $240,036 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R34AT013522 | Harmonized Healing: Personalized Music Interventions to Address Chronic Pain in People Living with HIV | 000 | 2 | NIH | 6/5/2026 | $240,827 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K99AG097920 | Integrating Multi-Omics to Uncover Microbial Aging Dynamics in Cognitive Health | 000 | 1 | NIH | 7/1/2026 | $135,540 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL173477 | Risk Factors and Outcomes of Multiple Cardiovascular Drug Intolerance in Women | 000 | 1 | NIH | 9/17/2026 | $623,711 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K00NS134140 | Mapping and Reprogramming Bioelectric Networks in Brain Cancer | 000 | 3 | NIH | 9/17/2026 | $91,152 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | U24CA306986 | National Cancer Institute Imaging Data Commons: improved sustainability and usability | 000 | 1 | NIH | 9/9/2026 | $836,291 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | F32AG099445 | Identifying the cellular consequences of ABCA7 genetic risk in Alzheimer's disease | 000 | 1 | NIH | 9/17/2026 | $81,280 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AT013252 | A multi-site feasibility clinical trial of GetHealthy-OA, a mind-body program for those with the combination of knee osteoarthritis, obesity, and depressive symptoms | 000 | 1 | NIH | 9/17/2026 | $1,591,498 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG079917 | Sleep Spindle Dynamics as a Clinical Biomarker of Aging, Alzheimer's Disease, and Trisomy 21 | 000 | 2 | NIH | 9/16/2026 | $831,903 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23MH142183 | Community-based HIV care for mobile populations in the Dominican Republic | 000 | 1 | NIH | 9/8/2026 | $189,542 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG094807 | Enhancing early detection and intervention for cognitive decline through FHIR-based clinical decision support | 000 | 1 | NIH | 9/16/2026 | $742,523 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL185474 | Testing the implementation and effectiveness of electronic health record-based interventions to improve hypertension control | 000 | 1 | NIH | 9/3/2026 | $908,994 |
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