| | | | | | | | | | | | | | | | |
| | |
 | Issue Date FY: 2026 ( Subtotal = $21,559,943 ) (Continued on the next page) |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | UM1AI069412 | Boston HIV CTU | 000 | 20 | NIH | 12/9/2025 | $2,578,146 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01ES034079 | Geospatially modeled environmental risk factors for lymphoid malignancies | 000 | 3 | NIH | 12/9/2025 | $687,459 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA288535 | Cell surface receptor targeted therapies for brain tumors | 000 | 2 | NIH | 12/18/2025 | $370,543 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K24AR085342 | Mentoring Patient-Oriented Research Leveraging Bioinformatics to Study CV Risk in Rheumatic Disease | 000 | 2 | NIH | 1/19/2026 | $171,396 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08NS136723 | Immune Regulation of the Blood-Brain Barrier | 000 | 2 | NIH | 12/17/2025 | $230,580 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01EB035091 | Abbreviated yet enhanced neuro MRI protocol | 000 | 2 | NIH | 12/5/2025 | $384,451 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA295752 | DNA damage-related stemness program during BRCA1 breast cancer initiation | 000 | 2 | NIH | 12/31/2025 | $477,805 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21AI182809 | Biomarkers predicting nasal polyp recurrence in aspirin-exacerbated respiratory disease | 000 | 2 | NIH | 12/31/2025 | $223,750 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01MH136503 | Using Neuroimaging to Investigate Mechanism-based Biomarkers of Schizophrenia | 001 | 2 | NIH | 1/9/2026 | $272,636 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01MH136503 | Using Neuroimaging to Investigate Mechanism-based Biomarkers of Schizophrenia | 000 | 2 | NIH | 1/8/2026 | $349,669 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI187513 | Rapid point of care Hepatitis C virus detection using a long-lasting luminescent cascade signal amplification | 000 | 2 | NIH | 12/4/2025 | $875,816 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K01AG080030 | Living beyond cancer: the short- and long-term cognitive effects of breast cancer and its treatment for cancer survivors | 000 | 4 | NIH | 1/14/2026 | $130,950 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI136041 | Eicosanoid Networks in Aspirin Hypersensitivity | 000 | 13 | NIH | 12/3/2025 | $656,461 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R03CA295675 | Mixed Lineage Kinase 2 (MLK2) in tumor angiogenesis | 000 | 2 | NIH | 1/13/2026 | $74,862 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HD113792 | Mechanics of Vertebrate Embryo Elongation | 000 | 3 | NIH | 12/15/2025 | $567,127 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI134989 | Type 2 Inflammation and Remodeling Elicited Through an LTE4/OXGR1-dependent pathway | 000 | 8 | NIH | 12/30/2025 | $712,176 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DK141535 | The role of SRCAP in therapy related clonal hematopoiesis | 000 | 2 | NIH | 12/15/2025 | $508,759 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K00CA274651 | Development of Lipid Nanoparticles for B-cell Mediated Immunotherapies | 000 | 4 | NIH | 12/10/2025 | $80,231 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HD114708 | An integrated intervention to address the double burden of maternal child malnutrition in Guatemala | 000 | 2 | NIH | 1/14/2026 | $370,115 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01NS136297 | Optimizing Neuromodulation Therapies for Epilepsy: Identifying the Right Patient, Right Place, and Right Time for Stimulation | 000 | 2 | NIH | 12/12/2025 | $590,408 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R21HD117308 | Continuous Non-Invasive Blood Pressure Monitoring in Neonates using Wearable Wireless NIRS | 000 | 2 | NIH | 12/12/2025 | $234,746 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI179986 | The novel role of MIF-CD74 inflammatory pathway in immune regulation | 000 | 3 | NIH | 12/5/2025 | $420,683 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K24AI180296 | Patient-Oriented Research Mentorship and Training in Upper Airway Allergic and Inflammatory Diseases | 000 | 3 | NIH | 12/10/2025 | $174,031 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI181221 | Interrogating Clonal Repertoire in Drug Hypersensitivity Reactions | 000 | 3 | NIH | 12/5/2025 | $865,521 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K02NS131521 | Restoring Cortical Network Function in Rett Syndrome | 000 | 3 | NIH | 1/13/2026 | $257,731 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DK039773 | Mechanisms of Ischemic Kidney Injury and Repair | 000 | 39 | NIH | 12/15/2025 | $712,313 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23AR080203 | Multi-omic Studies of Local and Systemic Immune Dysregulation in Rosacea | 000 | 5 | NIH | 1/7/2026 | $169,884 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01NS131182 | Chemogenetic Neurovascular Oxidative Stress: Neurodegeneration and Cardiac Remodeling | 000 | 3 | NIH | 1/19/2026 | $539,650 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI144166 | Role of Tim-3:Bat-3 pathway in inducing tolerogenic DCs and peripheral tolerance | 000 | 7 | NIH | 12/29/2025 | $512,496 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01NS131182 | Chemogenetic Neurovascular Oxidative Stress: Neurodegeneration and Cardiac Remodeling | 000 | 3 | NIH | 1/19/2026 | $159,177 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R37AI139536 | Neuroimmune interactions regulate development of allergic inflammation | 000 | 8 | NIH | 12/2/2025 | $602,703 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI179807 | Harnessing commensal redox metabolism in infection prevention | 000 | 3 | NIH | 12/4/2025 | $849,858 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01MH132632 | Control of ETV1 transcriptional networks in amygdalar astrocytes | 000 | 3 | NIH | 12/3/2025 | $434,860 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI165382 | KSHV Latency Regulation | 000 | 5 | NIH | 12/29/2025 | $691,972 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI175582 | Skin vaccination and generation of protective lung-tropic memory T cells | 000 | 3 | NIH | 11/26/2025 | $940,602 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AI176341 | A TCF1:Glucocorticoid regulatory circuit controls IL-23-driven Th17 pathogenicity | 000 | 4 | NIH | 12/10/2025 | $517,503 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01DK138260 | Development of novel PD1 agonist therapeutic strategies for inflammatory bowel disease | 000 | 3 | NIH | 12/22/2025 | $463,650 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K08ES034822 | Investigating environmental and gene-environment contributors to Parkinson's disease risk by coupling quantitative environmental exposure data to iPSC modeling | 000 | 4 | NIH | 12/31/2025 | $209,607 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01MD016910 | Disasters and Hospital Systems Serving Populations That Experience Health Disparities: Identifying the Long Term effects of Pandemics and Disasters in Order to Mitigate Future Challenges | 000 | 4 | NIH | 1/12/2026 | $588,461 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AR080194 | New approaches to safety monitoring of novel systemic treatments for atopic dermatitis in clinical practice and underrepresented populations | 000 | 5 | NIH | 1/8/2026 | $570,768 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG074899 | Autophagon: an Autophagy-Functionalizing Gene Therapy Tool for Neurodegenerative Diseases | 000 | 6 | NIH | 1/13/2026 | $672,524 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01AG082346 | Mechanisms of Somatic Mutation in Alzheimer's Disease Using Single Neuron Analysis | 000 | 3 | NIH | 12/11/2025 | $804,192 |
| | 2026 | 2026 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | K23DK125672 | Novel Pathways and Therapeutic Targets for Cisplatin-Associated Acute Kidney Injury | 000 | 5 | NIH | 12/19/2025 | $188,266 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01CA241817 | Development of Methods for a Simplified and Reliable Prostate Cancer MRI Exam | 000 | 5 | NIH | 12/16/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL161087 | Skin-Intrinsic Immunosuppressive Mesenchymal Stem Cells and aGVHD | 000 | 4 | NIH | 12/9/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | P41EB028741 | Advanced Technologies - National Center for Image Guided Therapy (AT-NCIGT) | 000 | 5 | NIH | 10/8/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | R01HL160799 | Targeting the Active Resolution of Inflammation for Cardiovascular Disease Prevention | 000 | 4 | NIH | 10/7/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | U01AI186972 | Harnessing Trained Immunity as a Radiation Medical Countermeasure | 000 | 1 | NIH | 11/26/2025 | $0 |
| | 2026 | 2025 | BRIGHAM & WOMENS HOSPITAL INC | 75 FRANCIS ST | BOSTON | MA | 02115-6110 | SUFFOLK | USA | U01AG089040 | Development, Validation, and Harmonization of Methods for Collection and Measurement of NAD+ and Related Metabolites: Application to a Randomized Trial of Patients Undergoing Coronary Artery Bypass | 001 | 2 | NIH | 1/16/2026 | $0 |
|
