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Training Program in NeuroHIV (TPNH)

Award Number: T32NS121780
ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 07/02/2021
PERIOD OF PERFORMANCE END DATE: 06/30/2026

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Training Program in NeuroHIV (TPNH) - Project Summary/Abstract This is a new application for an Institutional Training Grant in the basic and clinical aspects of Neurological Disorders caused by HIV, better known as HIV-associated neurocognitive disorders (HAND). The Training Program in NeuroHIV (TPNH) is requesting support for 4 advanced predoctoral students who will be trained in research on how HIV causes neural injury by faculty actively participating in the Neuroscience and Immunology programs at Georgetown University. The purpose of this training program is to prepare scientists to investigate molecular and cellular mechanisms of neurodegenerative processes as well as the immunological responses triggered by HIV. Our goal is to train researchers on the basic science aspect of developing neurotherapeutics and/or treatment strategies to reduce the neuronal and glial impairments that result from HIV infection of the brain. An experienced and well-funded group of 22 faculty members with a wide range of research interests and expertise in CNS function, neurodegeneration, virology and immunology will participate in the Ph.D. training program. Most students will enter graduate school through the Georgetown University Interdisciplinary Program in Neuroscience (IPN). In the first year they will take course work and rotate through the laboratories of potential mentors. In the second year, those interested in the TPNH will take specifically relevant courses dealing with neurodegenerative disorders, immunology, and immunopathogenesis of HIV infection, as well as extended integrative reasoning and statistical literacy training, and professional development training (i.e., grant writing and presentation skills). In the second year of graduate school, students will formally apply to the TPNH with the outline of a thesis research proposal approved by a potential mentor or co-mentors from the IPN/Immunology Training Faculty. Thesis research will start after the completion of the Ph.D. program’s qualifying exam. In their third and fourth years, trainees will participate in training sessions with clinician-scientists to provide the necessary experience in basic and clinical science that is key to the understanding of HAND from bench to therapeutics. Trainees will report results from their research in yearly student seminars, presentations at national meetings, and as publications in peer-reviewed journals. With respect to public health, this program will create a core of neuroscientists trained for research and/or management of research programs, through which new and more effective treatments for HAND and related neuro-immuno-degenerative disorders will be developed.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $174,800 )
2025	2025	GEORGETOWN UNIVERSITY	MAIN CAMPUS	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	5	6/26/2025	NON-COMPETING CONTINUATION	$174,800
														Subtotal = $174,800

Issue Date FY: 2024 ( Subtotal = $153,921 )
2024	2024	GEORGETOWN UNIVERSITY	MAIN CAMPUS	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	4	7/11/2024	NON-COMPETING CONTINUATION	$153,921
														Subtotal = $153,921

Issue Date FY: 2023 ( Subtotal = $173,834 )
2023	2023	GEORGETOWN UNIVERSITY	MAIN CAMPUS	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	3	6/30/2023	NON-COMPETING CONTINUATION	$173,834
														Subtotal = $173,834

Issue Date FY: 2022 ( Subtotal = $169,769 )
2022	2022	GEORGETOWN UNIVERSITY (THE)	37TH AND O ST NW	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	2	5/12/2022	NON-COMPETING CONTINUATION	$169,769
														Subtotal = $169,769

Issue Date FY: 2021 ( Subtotal = $83,034 )
2021	2021	GEORGETOWN UNIVERSITY (THE)	37TH AND O ST NW	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	1	7/2/2021	NEW	$83,034
														Subtotal = $83,034

Grand Total All Awards = $755,358

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Training Program in NeuroHIV (TPNH)

Award Number: T32NS121780

ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 07/02/2021

PERIOD OF PERFORMANCE END DATE: 06/30/2026

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