Monday, June 30, 2025 6/30/2025

Training in Developmental Hematology

Award Number: T32HL086345
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 04/01/2007
PERIOD OF PERFORMANCE END DATE: 05/31/2024

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Training in Developmental Hematology - PROJECT SUMMARY/ABSTRACT Studies in pediatric blood disorders provide an important paradigm for understanding the fundamental mechanisms regulating hematopoiesis. Unlike adult hematologic disorders, many pediatric diseases result from intrinsic genetic defects that control blood cell development or function. Understanding remains incomplete on the molecular pathogenesis of most of the hematologic diseases in children. At UCLA, we have a tremendous resource of interdisciplinary investigators whose research focuses on a wide spectrum of topics related to developmental hematology. Given the declining number of physician-scientists in Pediatric Hematology, a training program in Developmental Hematology is critical to produce the cadre of investigators who will continue to advance the field. Therefore, we propose a unique training program that focuses specifically on pediatric hematologic diseases by integrating a variety of disciplines, including molecular and cellular hematopoiesis, alternative organism models, stem cell transplantation and gene therapy, hemostasis and thrombosis, transfusion medicine, novel technologies (genomics, proteomics, gene editing, etc.), hematologic malignancies, therapeutics, and bioinformatics. In this application, we seek funding for 4 postdoctoral fellows per year for 5 years. The fellows will be either recent recipients of MD, MD/PhD, or PhD degrees undergoing postdoctoral training. We will emphasize recruitment to reflect the gender, racial, and ethnic diversity of our nation. Trainees will have the opportunity to develop research in one of the 22 faculty member's laboratories that bridge 12 Departments, providing trainees access to the incredibly diverse academic assets across the UCLA campus. The mentoring faculty have active and productive research programs and multiple mutual collaborations and publications, providing an ideal training environment. Trainees may also participate in an exchange program established with the NHLBI-funded T32 program at the University of Michigan (HL007622) to gain deeper knowledge of either hemostasis/thrombosis or hematopoietic stem cell transplantation, two academic strengths of their program (UM trainees may come to UCLA for training in cell and gene therapy). Trainees will be selected from a large pool of postdoctoral fellows based on their academic and research achievements. Appointments will be for 1-2 years, the second year appointment dependent on documented productivity. Trainees will take a required course on Developmental Hematology and receive training in principles of human subject research and the responsible conduct of research through courses in research ethics. They will participate in journal clubs and attend seminars and lectures related to pediatric hematology, stem cell biology, immunology and clinical research. Trainees will meet with a Scholarship Oversight Committee every 6 months to monitor progress and productivity. We will utilize the strengths of UCLA, including the breadth and depth of investigators across many disciplines, to train future researchers and leaders in the field of Pediatric Hematology.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = -$175,535 )
2025	2022	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Blood Diseases and Resources Research	001	15	10/30/2024	NON-COMPETING CONTINUATION	-$165,456
2025	2021	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Blood Diseases and Resources Research	000	14	10/30/2024	NON-COMPETING CONTINUATION	-$10,079
														Subtotal = -$175,535

Issue Date FY: 2022 ( Subtotal = $165,456 )
2022	2022	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Blood Diseases and Resources Research	000	15	5/20/2022	NON-COMPETING CONTINUATION	$165,459
2022	2022	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Blood Diseases and Resources Research	001	15	7/5/2022	NON-COMPETING CONTINUATION	-$3
														Subtotal = $165,456

Issue Date FY: 2021 ( Subtotal = $329,347 )
2021	2021	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Blood Diseases and Resources Research	000	14	6/21/2021	NON-COMPETING CONTINUATION	$329,347
														Subtotal = $329,347

Issue Date FY: 2020 ( Subtotal = $248,884 )
2020	2020	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90095	LOS ANGELES	USA	Blood Diseases and Resources Research	000	13	5/21/2020	NON-COMPETING CONTINUATION	$248,884
														Subtotal = $248,884

Issue Date FY: 2019 ( Subtotal = $308,490 )
2019	2019	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90095	LOS ANGELES	USA	Blood Diseases and Resources Research	000	12	5/20/2019	NON-COMPETING CONTINUATION	$308,490
														Subtotal = $308,490

Issue Date FY: 2018 ( Subtotal = $297,379 )
2018	2018	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90095	LOS ANGELES	USA	Blood Diseases and Resources Research	000	11	5/14/2018	COMPETING CONTINUATION	$297,379
2018	2018	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90095	LOS ANGELES	USA	Blood Diseases and Resources Research	002	11	8/6/2018	COMPETING CONTINUATION	$91,529
2018	2016	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90095	LOS ANGELES	USA	Blood Diseases and Resources Research	001	10	8/6/2018	EXTENSION WITH OR WITHOUT FUNDS	-$91,529
														Subtotal = $297,379

Issue Date FY: 2017 ( Subtotal = $0 )
2017	2016	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90095	LOS ANGELES	USA	Blood Diseases and Resources Research	001	10	10/31/2016	EXTENSION WITH OR WITHOUT FUNDS	$213,682
2017	2015	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90095	LOS ANGELES	USA	Blood Diseases and Resources Research	000	9	10/31/2016	NON-COMPETING CONTINUATION	-$213,682
														Subtotal = $0

Issue Date FY: 2016 ( Subtotal = $200,846 )
2016	2016	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Blood Diseases and Resources Research	000	10	5/13/2016	EXTENSION WITH OR WITHOUT FUNDS	$200,846
														Subtotal = $200,846

Issue Date FY: 2015 ( Subtotal = $234,931 )
2015	2015	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Blood Diseases and Resources Research	000	9	6/10/2015	NON-COMPETING CONTINUATION	$234,931
														Subtotal = $234,931

Issue Date FY: 2014 ( Subtotal = $216,787 )
2014	2014	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Blood Diseases and Resources Research	000	8	6/25/2014	NON-COMPETING CONTINUATION	$216,787
														Subtotal = $216,787

Issue Date FY: 2013 ( Subtotal = $270,913 )
2013	2013	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Blood Diseases and Resources Research	001	7	5/15/2013	NON-COMPETING CONTINUATION	$270,913
2013	2011	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Blood Diseases and Resources Research	000	5	3/28/2013	NON-COMPETING CONTINUATION	$0
														Subtotal = $270,913

Issue Date FY: 2012 ( Subtotal = $245,488 )
2012	2012	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Blood Diseases and Resources Research	000	6	5/10/2012	COMPETING CONTINUATION	$245,488
														Subtotal = $245,488

Issue Date FY: 2011 ( Subtotal = $199,490 )
2011	2011	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Blood Diseases and Resources Research	000	5	3/16/2011	NON-COMPETING CONTINUATION	$195,174
2011	2011	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Blood Diseases and Resources Research	001	5	6/7/2011	NON-COMPETING CONTINUATION	$4,316
														Subtotal = $199,490

Issue Date FY: 2010 ( Subtotal = $266,752 )
2010	2010	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Blood Diseases and Resources Research	000	4	2/16/2010	NON-COMPETING CONTINUATION	$266,752
														Subtotal = $266,752

Issue Date FY: 2009 ( Subtotal = $264,814 )
2009	2009	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Blood Diseases and Resources Research	000	3	3/24/2009	NON-COMPETING CONTINUATION	$264,814
														Subtotal = $264,814

Issue Date FY: 2008 ( Subtotal = $262,489 )
2008	2008	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Blood Diseases and Resources Research	000	2	2/27/2008	NON-COMPETING CONTINUATION	$262,489
														Subtotal = $262,489

Issue Date FY: 2007 ( Subtotal = $262,489 )
2007	2007	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	10920 WILSHIRE BLVD, 5TH FLOOR	LOS ANGELES	CA	90024	LOS ANGELES	USA	Blood Diseases and Resources Research	000	1	3/22/2007	NEW	$262,489
														Subtotal = $262,489

Grand Total All Awards = $3,599,020

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Training in Developmental Hematology

Award Number: T32HL086345

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 04/01/2007

PERIOD OF PERFORMANCE END DATE: 05/31/2024

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