Monday, June 30, 2025 6/30/2025

Transfusion Biology and Cellular Therapies

Award Number: T32HL066987
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 09/01/2001
PERIOD OF PERFORMANCE END DATE: 11/30/2027

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Transfusion Biology and Cellular Therapies - PROJECT SUMMARY For the past century, a major focus for Transfusion Medicine has been the immune compatibility of blood components with added attention to the safe and appropriate use of blood products. The success of these investigations has fueled expansive growth in the field with efforts focused on developing novel blood components for transfusion and to generate cellular therapies. These activities require a concerted effort to link advances in basic science with therapeutic interventions in the clinic. Transfusion Medicine Scientists and Specialists lead the effort to train individuals to advance blood and hematopoietic cellular therapies. The overall goal of the Program in Transfusion Biology and Cellular Therapies continues to be the preparation of M.D., M.D./Ph.D. or Ph.D. postdoctoral fellows for biomedical research careers. This long-standing program entering its third decade has supported 80 postdoctoral fellows with over 40% of trainees being women or underrepresented individuals. The T32 supports 8 postdoctoral fellows for 2-3 years enabling them to move on to leading positions in academia or industry. As the field of Transfusion Medicine continues to grow, as does the program to include the scientific areas around Immunobiology, Hematopoiesis, and Cellular Therapy. Major strengths of our multi-disciplinary program include utilizing the strong clinical and basic research environments at Harvard Medical School involving Boston Children's Hospital, Dana-Farber Cancer Institute, Brigham & Women's Hospital, and Massachusetts General Hospital. In addition to scientific investigation, we have developed programs to a) educate trainees in responsible conduct of research, grant writing, laboratory management, and ensuring rigor and reproducibility of data b) offer opportunities to develop skills in public speaking c) recruit and retain trainees from underrepresented or disadvantaged groups and d) maintain academic oversight for scholarship to advance career development. Dr. John Manis will continue his role as overall PI and has expanded the number of Program co-Directors to effectively represent both basic science and clinical Transfusion Medicine. These leaders will be responsible for the scientific direction of the training program, the mentoring of trainees as well as junior faculty, and monitoring milestones to ensure continued success. We have assembled our faculty roster this year to increase contemporary scientific representation from disciplines related to Transfusion and to better reflect the needs of our applicant pool. We believe our approach of including broad representation of clinical, basic and translational research talent is a fundamental strength of our program and fits well with the evolving field of Transfusion Biology and Cellular Therapies. This distinctive training approach has generated a unique environment for trainees in the Harvard Medical Area and ours remains a highly sought-after program. The outstanding pool of applicants and recruitment of faculty dedicated to the program has facilitated this goal. Our evolving Training Program strives to provide a unique and rich training environment for academic transfusion biology and cellular therapies.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $500,908 )
2025	2025	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	000	23	12/7/2024	NON-COMPETING CONTINUATION	$500,908
														Subtotal = $500,908

Issue Date FY: 2024 ( Subtotal = $305,829 )
2024	2024	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	003	22	12/1/2023	NON-COMPETING CONTINUATION	$257,696
2024	2024	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	010	22	8/22/2024	NON-COMPETING CONTINUATION	$48,133
2024	2023	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	002	21	11/6/2023	COMPETING CONTINUATION	$485,595
2024	2023	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	006	21	1/9/2024	COMPETING CONTINUATION	-$485,595
2024	2023	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	009	21	1/23/2024	COMPETING CONTINUATION	$485,595
2024	2021	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	001	20	11/6/2023	NON-COMPETING CONTINUATION	-$423,336
2024	2021	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	005	20	1/9/2024	NON-COMPETING CONTINUATION	$423,336
2024	2021	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	008	20	1/23/2024	NON-COMPETING CONTINUATION	-$423,336
2024	2020	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	007	19	1/23/2024	NON-COMPETING CONTINUATION	-$62,259
2024	2020	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	004	19	1/9/2024	NON-COMPETING CONTINUATION	$62,259
2024	2020	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	000	19	11/6/2023	NON-COMPETING CONTINUATION	-$62,259
														Subtotal = $305,829

Issue Date FY: 2023 ( Subtotal = $654,167 )
2023	2023	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	001	21	11/30/2022	COMPETING CONTINUATION	$636,961
2023	2023	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	002	21	3/14/2023	COMPETING CONTINUATION	$17,206
2023	2023	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	003	21	5/16/2023	COMPETING CONTINUATION	$0
2023	2021	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	000	20	11/29/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $654,167

Issue Date FY: 2022 ( Subtotal = $0 )
2022	2021	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	000	20	11/24/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2021 ( Subtotal = $423,336 )
2021	2021	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	000	20	2/24/2021	NON-COMPETING CONTINUATION	$423,336
														Subtotal = $423,336

Issue Date FY: 2020 ( Subtotal = $194,311 )
2020	2020	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	000	19	2/17/2020	NON-COMPETING CONTINUATION	$194,311
														Subtotal = $194,311

Issue Date FY: 2019 ( Subtotal = $394,924 )
2019	2019	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	000	18	3/8/2019	NON-COMPETING CONTINUATION	$394,924
														Subtotal = $394,924

Issue Date FY: 2018 ( Subtotal = $566,715 )
2018	2018	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	000	17	3/25/2018	NON-COMPETING CONTINUATION	$548,860
2018	2018	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	001	17	8/13/2018	NON-COMPETING CONTINUATION	$17,855
														Subtotal = $566,715

Issue Date FY: 2017 ( Subtotal = $3,976,247 ) (Continued on the next page)
2017	2017	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	017	16	5/2/2017	COMPETING CONTINUATION	$491,604
2017	2017	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	015	16	5/2/2017	COMPETING CONTINUATION	$491,604
2017	2017	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	012	15	4/4/2017	SUPPLEMENT FOR EXPANSION	-$2,592
2017	2017	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	003	15	2/6/2017	SUPPLEMENT FOR EXPANSION	$5,051
2017	2017	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	014	16	5/1/2017	COMPETING CONTINUATION	$491,604
2017	2017	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	013	15	4/4/2017	SUPPLEMENT FOR EXPANSION	-$2,592
2017	2017	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	018	16	5/2/2017	COMPETING CONTINUATION	$491,604
2017	2017	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	002	16	1/12/2017	COMPETING CONTINUATION	$535,019
2017	2017	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	011	15	4/4/2017	SUPPLEMENT FOR EXPANSION	-$5,051
2017	2017	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	008	16	4/4/2017	COMPETING CONTINUATION	$491,604
2017	2017	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	019	16	5/2/2017	COMPETING CONTINUATION	$491,604
2017	2017	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	010	15	4/4/2017	SUPPLEMENT FOR EXPANSION	-$5,051
2017	2017	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	009	16	4/4/2017	COMPETING CONTINUATION	$491,604
2017	2017	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	016	16	5/2/2017	COMPETING CONTINUATION	$491,604
2017	2017	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	007	16	4/4/2017	COMPETING CONTINUATION	$491,604
2017	2017	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	004	15	3/31/2017	SUPPLEMENT FOR EXPANSION	$2,592
2017	2017	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	021	16	5/2/2017	COMPETING CONTINUATION	$2,592
2017	2017	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	020	16	5/2/2017	COMPETING CONTINUATION	$5,051
2017	2016	CHILDREN'S HOSPITAL CORPORATION, THE	300 LONGWOOD AVE	BOSTON	MA	02115	SUFFOLK	USA	Blood Diseases and Resources Research	005	15	4/4/2017	EXTENSION WITH OR WITHOUT FUNDS	-$491,604
Grand Total All Awards = $12,775,325

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Transfusion Biology and Cellular Therapies

Award Number: T32HL066987

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 09/01/2001

PERIOD OF PERFORMANCE END DATE: 11/30/2027

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