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 | Issue Date FY: 2025 ( Subtotal = $4,017,988 ) (Continued on the next page) |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | F32DK130267 | The role of TTC7A in apical lumen formation and polarized trafficking in the intestinal epithelium | 000 | 3 | NIH | 10/30/2024 | $87,064 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI119918 | Mast cell regulation of Th2 induction and tolerance breakdown in food allergy | 000 | 10 | NIH | 11/8/2024 | $580,728 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL162367 | The Role of Adaptor Protein Disabled-2 in Maintaining Endothelial Cell Function in Atherosclerosis | 000 | 4 | NIH | 11/7/2024 | $661,395 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99HL171947 | Novel role of Foxc2 in regulating metabolic disease | 000 | 2 | NIH | 11/8/2024 | $125,658 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R13DC022523 | International Usher Syndrome Conference | 000 | 1 | NIH | 11/15/2024 | $60,000 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01CA255216 | Non-invasive imaging of the anti-tumor immune response | 000 | 5 | NIH | 11/13/2024 | $528,877 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | F32MD017452 | Sexual Minority Mental Health During the COVID-19 Pandemic: An Intersectional, Social Epidemiologic Investigation | 000 | 3 | NIH | 11/10/2024 | $78,784 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL167450 | Desmosomes in cardiomyocyte homeostasis and disease | 000 | 3 | NIH | 11/11/2024 | $717,809 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | F32AI189235 | Antiretroviral mechanisms of TRIM56 | 000 | 1 | NIH | 11/12/2024 | $77,284 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R13HL177876 | Hemoglobin Switching Meeting | 000 | 1 | NIH | 11/9/2024 | $10,000 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL163937 | CMYA5 regulation of cardiac dyad structure and function | 000 | 3 | NIH | 11/11/2024 | $541,964 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI180137 | Mechanism of the transcription factor FoxP3 in regulatory T cell development | 000 | 2 | NIH | 10/24/2024 | $772,604 |
| | 2025 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI148470 | A priori adaptive evolution predictions for antibiotic resistance through genome-wide network analyses and machine learning | 000 | 5 | NIH | 11/14/2024 | $0 |
| | 2025 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AG071326 | Defining the Role of Poly ADP-ribose in Biomolecular Condensation in ALS and FTLD | 000 | 2 | NIH | 11/8/2024 | $1,084,589 |
| | 2025 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R35GM145368 | Discovery of novel regulatory territories in the TNF/LT locus | 000 | 3 | NIH | 11/8/2024 | $0 |
| | 2025 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K25AI177810 | Understand the mechanism of SARS-CoV-2 entry by single-molecule approaches | 000 | 1 | NIH | 11/8/2024 | -$120,258 |
| | 2025 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R35GM119537 | Mechanical forces in nanoscale biology: From hemostasis to single-molecule centrifugation | 000 | 9 | NIH | 11/6/2024 | $0 |
| | 2025 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R35GM122569 | Single molecule and biophysical studies of nucleic acid remodeling | 000 | 8 | NIH | 11/7/2024 | $0 |
| | 2025 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R35GM131728 | Prolonged duration and triggered local anesthesia | 000 | 6 | NIH | 11/15/2024 | $0 |
| | 2025 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R34DA060500 | Developing a Telehealth + mHealth Cannabis Use Intervention for Young Adults (MOMENT-V) | 000 | 1 | NIH | 11/5/2024 | $0 |
| | 2025 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R35GM133725 | Unraveling heterogeneity of molecular mechanisms in cellular motility and morphodynamics by machine learning | 000 | 7 | NIH | 11/5/2024 | $0 |
| | 2025 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K01AR078975 | Trans-megakaryocyte migration as neutrophil amplifier | 000 | 3 | NIH | 11/4/2024 | -$5,627 |
| | 2025 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R61NS126792 | Consortium Of MRI Biomarkers In Neonatal Encephalopathy (COMBINE) | 000 | 3 | NIH | 10/17/2024 | $0 |
| | 2025 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | UH3HL157564 | A Phase III Randomized Trial Comparing Unrelated Donor Bone Marrow Transplantation with Immune Suppressive Therapy for Newly Diagnosed Pediatric and Young Adult Patients with Severe Aplastic Anemia | 000 | 3 | NIH | 10/22/2024 | $0 |
| | 2025 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01CA193651 | Defining and targeting asparaginase resistance mechanisms in high-risk acute leukemias | 000 | 10 | NIH | 10/22/2024 | -$373,507 |
| | 2025 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R03NS127044 | Combining Brain Connectivity and Excitability to Plan Epilepsy Surgery in Children: A New Approach to Augment Presurgical Intracranial Electroencephalography | 000 | 2 | NIH | 10/10/2024 | $0 |
| | 2025 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | UE5NS070682 | CH/BIDMC/Harvard Medical School Neurology Resident Research Education Program | 000 | 15 | NIH | 10/17/2024 | $0 |
| | 2025 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21DA058120 | Depot formulations for on-demand tamper- and diversion-proof delivery of opioids | 000 | 1 | NIH | 10/17/2024 | $0 |
| | 2025 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R35GM134953 | Wnt Signaling and Vertebrate embryogenesis | 000 | 5 | NIH | 11/6/2024 | $0 |
| | 2025 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K08DK125878 | Role of intestinal luminal and epigenetic factors to mediate intestinal metabolic remodeling after gastric bypass surgery - Administrative Supplement | 001 | 4 | NIH | 11/14/2024 | $0 |
| | 2025 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K08DK125878 | Role of intestinal luminal and epigenetic factors to mediate intestinal metabolic remodeling after gastric bypass surgery - Administrative Supplement | 000 | 4 | NIH | 11/14/2024 | $0 |
| | 2025 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | UH3CA243120 | Natural Language Processing Platform for Cancer Surveillance | 000 | 5 | NIH | 11/6/2024 | -$7,805 |
| | 2025 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21DA058072 | Impact of Prolonged Perioperative Sedation on Infant Brain | 000 | 1 | NIH | 10/21/2024 | $0 |
| | 2025 | 2022 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01GM127600 | Surgical site infections and the role of anesthesia and bacterial ion transporters | 000 | 3 | NIH | 11/14/2024 | $0 |
| | 2025 | 2022 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | U24NS107183 | Boston Children's Hospital and Beth Israel Deaconess Medical Center NeuroNEXT Clinical Research Site | 001 | 5 | NIH | 11/14/2024 | -$349,842 |
| | 2025 | 2022 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01DK119488 | Regulation of the Intestinal Stem Cells During Regeneration | 000 | 4 | NIH | 11/7/2024 | $0 |
| | 2025 | 2022 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AR071342 | The LRP5 Pathway and Osteoblast Function In Osteogenesis Imperfecta | 000 | 5 | NIH | 10/18/2024 | -$155,899 |
| | 2025 | 2022 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI139633 | Mechanisms of a Novel Combined Immunodeficiency Caused by a Homozygous Mutation in COPG1 | 000 | 5 | NIH | 10/24/2024 | $0 |
| | 2025 | 2022 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI139633 | Mechanisms of a Novel Combined Immunodeficiency Caused by a Homozygous Mutation in COPG1 | 001 | 5 | NIH | 10/24/2024 | $0 |
| | 2025 | 2022 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01NS113591 | Disrupted Ciliary Signaling in the Brain Pathology of Tuberous Sclerosis Complex | 000 | 4 | NIH | 10/16/2024 | -$75,548 |
| | 2025 | 2022 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01NS113591 | Disrupted Ciliary Signaling in the Brain Pathology of Tuberous Sclerosis Complex | 001 | 4 | NIH | 10/16/2024 | -$23,259 |
| | 2025 | 2022 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01DK098496 | Endoplasmic Reticulum Stress, Brain and Obesity | 000 | 8 | NIH | 10/16/2024 | $0 |
| | 2025 | 2022 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01CA216188 | Mechanisms of tumorigenesis in Brg1 mutant lung cancer | 000 | 5 | NIH | 10/11/2024 | $0 |
| | 2025 | 2022 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | 90AX0022 | Pop Health on FLAT FHIR: A SMART Approach to Universal Healthcare Reporting | 06 | 1 | DHHS/OS | 10/4/2024 | $0 |
| | 2025 | 2021 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01DK076683 | Discover and functionally characterize full-penetrance causes of nephrosis / FSGS | 000 | 16 | NIH | 11/13/2024 | -$144,755 |
| | 2025 | 2021 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | U24NS107183 | Boston Children's Hospital and Beth Israel Deaconess Medical Center NeuroNEXT Clinical Research Site | 000 | 4 | NIH | 11/14/2024 | -$52,267 |
| | 2025 | 2020 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | 90AX0031 | Cumulus: A Universal Research Sidecar for a SMART Learning Healthcare System | 03 | 1 | DHHS/OS | 10/4/2024 | $0 |
| | 2025 | 2020 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | 90AX0022 | Pop Health on FLAT FHIR: A SMART Approach to Universal Healthcare Reporting | 06 | 1 | DHHS/OS | 10/4/2024 | $0 |
| | 2025 | 2019 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | 90AX0022 | Pop Health on FLAT FHIR: A SMART Approach to Universal Healthcare Reporting | 06 | 1 | DHHS/OS | 10/4/2024 | $0 |
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