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 | Issue Date FY: 2025 ( Subtotal = $209,008,293 ) (Continued on the next page) |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | F32MD017452 | Sexual Minority Mental Health During the COVID-19 Pandemic: An Intersectional, Social Epidemiologic Investigation | 001 | 3 | NIH | 3/22/2025 | $0 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | F32MD017452 | Sexual Minority Mental Health During the COVID-19 Pandemic: An Intersectional, Social Epidemiologic Investigation | 000 | 3 | NIH | 11/10/2024 | $78,784 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL155632 | Transcription Factor 4 Maintain Endothelial identity to Oppose Heart Failure | 001 | 4 | NIH | 8/12/2025 | $50,171 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL155632 | Transcription Factor 4 Maintain Endothelial identity to Oppose Heart Failure | 000 | 4 | NIH | 11/19/2024 | $451,532 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01EB032708 | Fetal MRI: robust self-driving brain acquisition and body movement quantification | 001 | 4 | NIH | 5/19/2025 | $69,278 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01EB032708 | Fetal MRI: robust self-driving brain acquisition and body movement quantification | 000 | 4 | NIH | 11/26/2024 | $623,514 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI180137 | Mechanism of the transcription factor FoxP3 in regulatory T cell development | 001 | 2 | NIH | 6/25/2025 | $0 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL181969 | Optimizing HCT Outcomes: A Multi-omic Investigation | 000 | 1 | NIH | 8/11/2025 | $2,024,340 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI112652 | Global regulators converge to orchestrate metabolism, biofilm, and pathogenesis | 000 | 9 | NIH | 2/13/2025 | $577,362 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AI180552 | Structural studies of the full-length nucleocapsid protein of SARS-CoV-2 | 000 | 1 | NIH | 7/23/2025 | $489,500 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL176663 | Investigating the pro-regenerative potential of Pontin in the heart. | 000 | 1 | NIH | 7/30/2025 | $833,594 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01EB037186 | Motion and distortion-robust quantitative MRI of early brain developments | 000 | 1 | NIH | 7/29/2025 | $511,583 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AI180611 | C. albicans cell wall stress responses and TOR signaling | 000 | 1 | NIH | 7/28/2025 | $489,500 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI182177 | Armed nanobodies as anti-infectives and anti-tumor agents | 001 | 2 | NIH | 5/23/2025 | $299,967 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI182177 | Armed nanobodies as anti-infectives and anti-tumor agents | 001 | 2 | NIH | 5/23/2025 | $242,933 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K23DK127251 | Effect of Thickened Feeds on Swallow Physiology and Clinical Outcomes in Children with Brief Resolved Unexplained Event | 000 | 5 | NIH | 2/26/2025 | $194,940 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | RF1NS142871 | Transposable Element Mobilization and Disrupted Translational Machinery in Down Syndrome | 000 | 1 | NIH | 7/30/2025 | $1,274,904 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI169648 | Functional investigation of a novel and essential subcellular compartment in Plasmodium falciparum transmission stage parasites | 000 | 4 | NIH | 2/18/2025 | $687,521 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AI194232 | Human cellular models of TB and innate immunity | 000 | 1 | NIH | 7/23/2025 | $489,500 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL182042 | Developing a spatiotemporal lineage map of heart development | 000 | 1 | NIH | 7/24/2025 | $865,286 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R13AR086669 | Development of a Pediatric Rheumatology Common Data Element set (CDE) for Juvenile Idiopathic Arthritis | 000 | 1 | NIH | 7/24/2025 | $1 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | F32GM159374 | Investigating BMAL1-RNA interactions and their roles in circadian rhythms | 000 | 1 | NIH | 7/25/2025 | $81,040 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R13AR086669 | Development of a Pediatric Rheumatology Common Data Element set (CDE) for Juvenile Idiopathic Arthritis | 000 | 1 | NIH | 7/24/2025 | $74,833 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AI185295 | Unravelling the role of aDb2 as a novel complement receptor in lung injury | 000 | 1 | NIH | 7/23/2025 | $489,500 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K01NS142019 | Role of KMT2D in neurodevelopmental disorders | 000 | 1 | NIH | 8/6/2025 | $241,380 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01CA295865 | Evaluating Pathways Involved in Melanoma Initiation | 000 | 1 | NIH | 7/29/2025 | $679,604 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01MH130356 | Effects of 16p11.2 copy number variation on neuronal development and pathology | 000 | 3 | NIH | 2/19/2025 | $699,666 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL158192 | High resolution lineage tracing of developmental hematopoiesis | 001 | 3 | NIH | 7/16/2025 | $74,310 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI175556 | Mechanisms of enhanced food allergy by S. aureus skin colonization in Atopic Dermatitis | 000 | 3 | NIH | 2/12/2025 | $757,963 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL158192 | High resolution lineage tracing of developmental hematopoiesis | 000 | 3 | NIH | 3/6/2025 | $668,787 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R37NS109211 | Kinetochore Protein Functions in Synaptogenesis | 002 | 7 | NIH | 8/4/2025 | $619,447 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21EB036775 | Ex vivo and In vivo Model Advancements for Airway Stent Design Optimization | 000 | 1 | NIH | 7/4/2025 | $222,500 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HS028930 | A Multicenter Randomized Controlled Trial of a Patient Safety Reporting Intervention for Families to Improve Medical Error Detection and Reduce Inequities | 000 | 4 | AHRQ | 2/10/2025 | $199,324 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD119283 | Neuroendocrine computations underlying an enduring behavioral state | 000 | 1 | NIH | 8/13/2025 | $571,485 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K00NS129126 | Epilepsy Mechanisms and the Path to Intervention | 000 | 3 | NIH | 8/13/2025 | $85,752 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K08AG086586 | Elucidating the neuronal mechanisms underlying cognitive resilience to Alzheimer's Disease | 000 | 1 | NIH | 8/8/2025 | $167,940 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AI188071 | Overcoming obstacles in structural elucidation of B cell antigen receptor assembly and lateral interaction | 000 | 1 | NIH | 7/9/2025 | $489,500 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL152358 | Exploring the relationship between advanced multimodal brain MRI phenotypes, genes and cognitive outcome in adults with CHD | 001 | 5 | NIH | 8/4/2025 | $78,258 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL152358 | Exploring the relationship between advanced multimodal brain MRI phenotypes, genes and cognitive outcome in adults with CHD | 000 | 5 | NIH | 2/15/2025 | $704,328 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | U01AI152033 | Genetic and microbial modifiers of Atopic Dermatitis (AD): Mechanisms of increased AD severity in patients with the R576 polymorphism in IL-4Ra and impact of S aureus skin decolonization on AD | 000 | 6 | NIH | 3/11/2025 | $510,170 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL096384 | Blood vessel assembly from multipotent hemangioma-derived stem cells | 002 | 14 | NIH | 4/14/2025 | $661,475 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01NS120986 | Predicting ASD and Other Developmental Outcomes in the First Year of Life Using EEG in a Diverse Community-Based Sample (Revision) | 001 | 4 | NIH | 5/16/2025 | $624,623 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01NS120986 | Predicting ASD and Other Developmental Outcomes in the First Year of Life Using EEG in a Diverse Community-Based Sample (Revision) | 000 | 4 | NIH | 2/13/2025 | $594,360 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01DA050589 | Understanding neuronal subtype-specific function of NAc in cocaine addiction | 000 | 5 | NIH | 2/28/2025 | $650,703 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01DA050589 | Understanding neuronal subtype-specific function of NAc in cocaine addiction | 001 | 5 | NIH | 4/10/2025 | $72,301 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01CA287076 | Activating gasdermin pores to induce pyroptosis and stimulate anti-tumor immunity | 001 | 2 | NIH | 5/22/2025 | $73,306 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01CA287076 | Activating gasdermin pores to induce pyroptosis and stimulate anti-tumor immunity | 000 | 2 | NIH | 3/3/2025 | $659,763 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99HL169927 | Deciphering the intrinsic myocardial and/or endocardial defects of hypoplastic left heart syndrome | 000 | 2 | NIH | 2/21/2025 | $127,278 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | U19AI158076 | Attacking failure of antibiotic treatment by targeting antimicrobial resistance enabler cell-states | 003 | 4 | NIH | 6/27/2025 | $2,470,464 |
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