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 | Issue Date FY: 2026 ( Subtotal = $274,655,920 ) (Continued on the next page) |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99AI199041 | Dissecting priming and activation mechanisms of NLRP3 against inflammatory diseases | 000 | 1 | NIH | 5/15/2026 | $124,992 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL179819 | Molecular Regulation of Atherosclerosis | 000 | 1 | NIH | 7/14/2026 | $1,628,604 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99AA032854 | Molecular mechanisms underlying alcohol-induced congenital heart defects | 000 | 1 | NIH | 7/29/2026 | $162,483 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI192967 | Immune Regulatory Functions of DOCK-STAT complexes | 000 | 1 | NIH | 6/16/2026 | $700,957 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL185725 | HIF2a-VIM-COX4I2 Axis Orchestrates Pericyte Cytoskeletal-Mitochondrial Crosstalk to Drive Pulmonary Vascular Remodeling | 000 | 1 | NIH | 8/14/2026 | $1,775,277 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99HD122217 | Elucidating mechanisms underlying pediatric erythromelalgia | 000 | 1 | NIH | 7/22/2026 | $126,468 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R33NS131704 | Gene Therapy for Succinic Semialdehyde Dehydrogenase Deficiency (SSADHD) | 000 | 3 | NIH | 7/24/2026 | $342,719 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K23DK149487 | Nucleoside Therapy in Patients with Telomere Biology Disorders | 000 | 1 | NIH | 7/31/2026 | $195,900 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI193134 | Integrins α4β7 in Leukocyte Rolling in Shear Flow, Firm Adhesion, and Therapy | 000 | 1 | NIH | 6/11/2026 | $889,904 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K23HL188353 | Use of Ventilatory Metrics in Pediatric Obstructive Sleep Apnea | 000 | 1 | NIH | 8/28/2026 | $171,600 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD121633 | Hydrogen in neonatal encephalopathy (HIE) Trial | 001 | 1 | NIH | 8/25/2026 | -$493,832 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99HL183664 | Targeting Angiocrine Signaling in Vascular Repair and Ischemic Stroke Recovery | 000 | 1 | NIH | 7/22/2026 | $139,822 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD121633 | Hydrogen in neonatal encephalopathy (HIE) Trial | 000 | 1 | NIH | 8/14/2026 | $182,000 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD121633 | Hydrogen in neonatal encephalopathy (HIE) Trial | 000 | 1 | NIH | 8/14/2026 | $1,400,000 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD121633 | Hydrogen in neonatal encephalopathy (HIE) Trial | 000 | 1 | NIH | 8/14/2026 | $1,347,616 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD121633 | Hydrogen in neonatal encephalopathy (HIE) Trial | 000 | 1 | NIH | 8/14/2026 | $988,448 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AG103841 | Prion-like properties of CLOCK as a protective reservoir for circadian timekeeping | 000 | 1 | NIH | 7/17/2026 | $489,500 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01DK144099 | The use of high bile-binding foods to reduce upper gastrointestinal bile acid concentrations: A novel intervention for children at risk for aspiration-associated complications | 000 | 1 | NIH | 8/4/2026 | $600,147 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL188153 | Transparent Artificial Intelligence from Clinical Text, ECGs, and Imaging for Pediatric Cardiology | 000 | 1 | NIH | 9/1/2026 | $857,878 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AA033213 | Characterization of Physical and Emotional Pain During the Protracted Withdrawal Stage of Alcohol Use Disorder | 000 | 1 | NIH | 8/3/2026 | $489,479 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R56NS150428 | Evaluating Candidate Genes for Evidence of Epilepsy | 000 | 1 | NIH | 8/28/2026 | $577,573 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01DA062669 | Functions and mechanisms of a molecularly defined prefrontal cortex neuron subtype in drug addiction | 000 | 1 | NIH | 4/28/2026 | $800,131 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R61AI197819 | Develop delivery systems and therapeutic proteins for reversal of botulinum neurotoxin intoxication | 000 | 1 | NIH | 5/22/2026 | $534,000 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R03DK144355 | Saliva biomarkers of aspiration in infants with brief resolved unexplained events | 000 | 1 | NIH | 5/22/2026 | $133,500 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI198376 | Leveraging human genetics to decipher B cell activation dysregulation in lupus | 001 | 1 | NIH | 8/12/2026 | $0 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI198376 | Leveraging human genetics to decipher B cell activation dysregulation in lupus | 000 | 1 | NIH | 5/20/2026 | $905,875 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | 90DDUC0142 | University Centers for Excellence in Developmental Disabilities, Education and Service | 00 | 4 | ACL | 7/1/2026 | $629,042 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R61NS130215 | Development and Validation of a Nocturnal Sleep Signature for the Diagnosis of Idiopathic Hypersomnia | 000 | 3 | NIH | 5/18/2026 | $465,931 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99HG013991 | Deciphering Determinants of Somatic Evolution with Single-Cell Genealogy | 000 | 2 | NIH | 1/31/2026 | $126,830 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01DA056771 | Engineering CAR-B cells for an HIV-1 functional cure | 000 | 5 | NIH | 5/20/2026 | $714,822 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01NS120986 | Predicting ASD and Other Developmental Outcomes in the First Year of Life Using EEG in a Diverse Community-Based Sample | 002 | 5 | NIH | 9/1/2026 | $0 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01NS120986 | Predicting ASD and Other Developmental Outcomes in the First Year of Life Using EEG in a Diverse Community-Based Sample | 001 | 5 | NIH | 3/2/2026 | $126,544 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01NS120986 | Predicting ASD and Other Developmental Outcomes in the First Year of Life Using EEG in a Diverse Community-Based Sample | 000 | 5 | NIH | 12/12/2025 | $1,138,899 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01CA287076 | Activating gasdermin pores to induce pyroptosis and stimulate anti-tumor immunity | 000 | 3 | NIH | 4/1/2026 | $733,069 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL096384 | Blood vessel assembly from multipotent hemangioma-derived stem cells | 000 | 15 | NIH | 4/2/2026 | $704,496 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL171206 | Mechanistic dissection of 22q11.2DS in zebrafish | 001 | 3 | NIH | 4/23/2026 | $18,637 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | U01AI152033 | Genetic and microbial modifiers of Atopic Dermatitis (AD): Mechanisms of increased AD severity in patients with the R576 polymorphism in IL-4Ra and impact of S aureus skin decolonization on AD | 001 | 7 | NIH | 8/17/2026 | $0 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL171206 | Mechanistic dissection of 22q11.2DS in zebrafish | 000 | 3 | NIH | 3/11/2026 | $590,171 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | U01AI152033 | Genetic and microbial modifiers of Atopic Dermatitis (AD): Mechanisms of increased AD severity in patients with the R576 polymorphism in IL-4Ra and impact of S aureus skin decolonization on AD | 000 | 7 | NIH | 4/3/2026 | $525,764 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K08AI187736 | The Establishment of Lung Resident Self-Antigen-Specific CD4+ Tregs Following Acute Tissue injury | 000 | 2 | NIH | 2/13/2026 | $194,740 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI189786 | Characterization of a novel post-transcriptional regulator in P. aeruginosa | 000 | 2 | NIH | 1/29/2026 | $873,988 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL152133 | Enhancing endothelial cell engraftment via transplantation of exogenous mitochondria | 000 | 5 | NIH | 5/4/2026 | $844,303 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AR083139 | Engineering self-assembled skin-on-a-chip | 001 | 3 | NIH | 5/5/2026 | $34,033 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AR083139 | Engineering self-assembled skin-on-a-chip | 000 | 3 | NIH | 2/11/2026 | $612,585 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99EY037374 | Transformations of photic information in melanopsin pathways | 000 | 2 | NIH | 7/22/2026 | $136,512 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99HG013662 | Computational Technology for Single-Cell Functional Genomics | 000 | 2 | NIH | 7/24/2026 | $130,680 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01DK123694 | Rosettes in Adrenal Development, Maintenance and Disease | 000 | 8 | NIH | 7/7/2026 | $755,828 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K23MD016171 | Developing an engagement intervention for Black and Latino caregivers to improve children’s receipt of mental health services after sexual abuse. | 000 | 5 | NIH | 6/16/2026 | $167,940 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01MH129636 | Predicting psychosis risk in youth using a novel structural neuroimaging score that measures deviation from normative development. Can we bring it to communities using portable, low-field MRI? | 000 | 5 | NIH | 2/24/2026 | $749,537 |
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