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 | Issue Date FY: 2026 ( Subtotal = $206,507,310 ) (Continued on the next page) |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL167513 | Targeting ZNF410 for HbF reactivation | 000 | 4 | NIH | 4/6/2026 | $658,954 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | U19AI189176 | Immunization against Multidrug-resistant Pathogens: Activating T Cell Immunity (IMPACT-CETR) | 001 | 2 | NIH | 7/1/2026 | $5,179,700 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R00HL184327 | Organ specific effects of platelet transfusions in neonates | 000 | 1 | NIH | 5/4/2026 | $443,978 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01DK142931 | Genomically-driven discovery of pediatric steroid sensitive nephrotic syndrome. | 000 | 1 | NIH | 1/22/2026 | $893,823 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01MH130356 | Effects of 16p11.2 copy number variation on neuronal development and pathology | 000 | 4 | NIH | 3/24/2026 | $813,612 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL158192 | High resolution lineage tracing of developmental hematopoiesis | 001 | 4 | NIH | 3/24/2026 | $22,059 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL158192 | High resolution lineage tracing of developmental hematopoiesis | 000 | 4 | NIH | 2/26/2026 | $698,536 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI175556 | Mechanisms of enhanced food allergy by S. aureus skin colonization in Atopic Dermatitis | 000 | 4 | NIH | 2/9/2026 | $781,407 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99AI187733 | Macrophage identity as a function of cell of origin | 000 | 2 | NIH | 7/16/2026 | $119,599 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21EB036775 | Ex vivo and In vivo Model Advancements for Airway Stent Design Optimization | 000 | 2 | NIH | 5/22/2026 | $267,000 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD119283 | Neuroendocrine computations underlying an enduring behavioral state | 001 | 2 | NIH | 5/27/2026 | $578,771 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K01AR085194 | Non-coding genetic risk variants modulating Tregs in arthritis | 000 | 2 | NIH | 7/8/2026 | $122,563 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI182177 | Armed nanobodies as anti-infectives and anti-tumor agents | 000 | 3 | NIH | 6/3/2026 | $299,967 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI182177 | Armed nanobodies as anti-infectives and anti-tumor agents | 000 | 3 | NIH | 6/3/2026 | $242,933 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | U01NS142013 | BRAIN CONNECTS: FAST-ET: fast automated serial tape-enabled electron tomography | 001 | 2 | NIH | 7/8/2026 | -$950,000 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | U01NS142013 | BRAIN CONNECTS: FAST-ET: fast automated serial tape-enabled electron tomography | 001 | 2 | NIH | 7/8/2026 | $950,000 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | U01NS142013 | BRAIN CONNECTS: FAST-ET: fast automated serial tape-enabled electron tomography | 000 | 2 | NIH | 6/30/2026 | $1,101,231 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K01NS142019 | Role of KMT2D in neurodevelopmental disorders | 000 | 2 | NIH | 7/10/2026 | $241,380 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI169648 | Functional investigation of a novel and essential subcellular compartment in Plasmodium falciparum transmission stage parasites | 000 | 5 | NIH | 2/13/2026 | $691,084 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01EB037186 | Motion and distortion-robust quantitative MRI of early brain developments | 000 | 2 | NIH | 5/19/2026 | $484,883 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI181618 | HIV-1 membrane fusion and inhibition | 000 | 3 | NIH | 3/30/2026 | $752,675 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | T32HD098061 | Neonatal Research Training Program | 000 | 8 | NIH | 4/10/2026 | $499,031 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL181969 | Optimizing HCT Outcomes: A Multi-omic Investigation | 001 | 2 | NIH | 5/19/2026 | $1,913,626 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD119407 | Motion-Robust Iron Quantification of Newborn Brains using Radial MRI | 000 | 2 | NIH | 5/28/2026 | $571,403 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K01DK142040 | Mechanisms of clonal competition in age related clonal hematopoiesis | 000 | 2 | NIH | 6/11/2026 | $153,360 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI187854 | Mechanism of inflammation in deficiency of adenosine deaminase 2 | 000 | 2 | NIH | 6/25/2026 | $531,424 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R35CA305089 | Effect of tumor editing on antitumor immunity | 000 | 2 | NIH | 6/25/2026 | $881,707 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01NS142815 | Dissecting Neural Circuits for Top-Down Control of Sympathetic Functions | 000 | 1 | NIH | 1/15/2026 | $674,950 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI192655 | Mechanisms of control of allergic skin inflammation by T regulatory cells | 000 | 2 | NIH | 6/26/2026 | $696,781 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K23MD016171 | Developing an engagement intervention for Black and Latino caregivers to improve children’s receipt of mental health services after sexual abuse. | 000 | 5 | NIH | 6/16/2026 | $167,940 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K08AG086586 | Elucidating the neuronal mechanisms underlying cognitive resilience to Alzheimer's Disease | 000 | 2 | NIH | 5/20/2026 | $167,940 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD091142 | Natural History of Succinic Semialdehyde Dehydrogenase Deficiency (SSADHD), a Heritable Disorder of GABA Metabolism | 001 | 8 | NIH | 7/21/2026 | $50,208 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD091142 | Natural History of Succinic Semialdehyde Dehydrogenase Deficiency (SSADHD), a Heritable Disorder of GABA Metabolism | 000 | 8 | NIH | 7/3/2026 | $649,604 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01DK123694 | Rosettes in Adrenal Development, Maintenance and Disease | 000 | 8 | NIH | 7/7/2026 | $755,828 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01DK143991 | Stress Granules in Red Blood Cell Development | 000 | 2 | NIH | 7/22/2026 | $801,000 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD119047 | Mental and Behavioral Health Among Bisexual Adolescents and Young Adults in the United States | 000 | 2 | NIH | 6/23/2026 | $732,230 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K08HD121809 | Dissecting the Genetic and Phenotypic Architecture of Stillbirth and Fetal Structural Anomalies to Improve Prenatal Diagnosis | 000 | 1 | NIH | 6/26/2026 | $167,400 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R61MH139596 | Developing Cognitive Control and Metacognition to Reduce the Functional Impact of Restricted and Repetitive Behaviors in Autism | 000 | 1 | NIH | 3/9/2026 | $990,550 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AI199018 | Molecular Mechanisms of Aire in Transcriptional Regulation | 000 | 1 | NIH | 4/17/2026 | $267,000 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99EY037821 | Targeting SARM1 as a Therapeutic Strategy for Autosomal Dominant Optic Atrophy (ADOA) and Leber Hereditary Optic Neuropathy (LHON) | 000 | 1 | NIH | 4/17/2026 | $132,837 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K08DK142004 | Mechanisms of hypothalamic-pituitary-adrenal axis suppression and recovery after long-term glucocorticoids | 000 | 1 | NIH | 4/17/2026 | $168,543 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AI199164 | Regulation of Alloimmunity by B Cells | 000 | 1 | NIH | 7/6/2026 | $267,000 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99HL179259 | Mechanisms of endothelial cell differentiation during vasculogenesis | 000 | 1 | NIH | 5/7/2026 | $139,822 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01CA307299 | Tumor suppressor function of p190 RhoGAP | 000 | 1 | NIH | 6/30/2026 | $578,559 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99HL186058 | Endocardial S1PR1 Internalization Drives Congenital Heart Disease via Notch Signaling Dysregulation | 000 | 1 | NIH | 5/12/2026 | $144,817 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI184490 | Regulation of innate immunity by the pathogen Staphylococcus aureus | 000 | 1 | NIH | 2/19/2026 | $800,557 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | F32HL186603 | Investigating the spatial and temporal regulation of nkx2.5+ ALPM progenitors in outflow tract development | 000 | 1 | NIH | 7/1/2026 | $82,348 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI198262 | Determining the Age-specific Mechanisms of Action of three newly discovered Adjuvant Combinations Using Human in vitro models and age-specific in vivo models | 000 | 1 | NIH | 7/16/2026 | $727,080 |
| | 2026 | 2026 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL180800 | Emperipolesis as a driver of platelet heterogeneity and function | 000 | 1 | NIH | 7/7/2026 | $1,733,846 |
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