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 | Issue Date FY: 2024 ( Subtotal = $97,270,292 ) (Continued on the next page) |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL167723 | Sphingolipid signaling in the endothelium during viral host defense | 000 | 1 | NIH | 12/20/2023 | $712,226 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | U01AI181964 | Consortium for food allergy research clinical center CoFar | 000 | 1 | NIH | 3/11/2024 | $380,000 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21NS135389 | Mitigating Post-Traumatic Epileptogenesis by Enhancing Synaptic Glutamate Transport via Long-Term Non-Bactericidal Beta-Lactam Administration | 000 | 1 | NIH | 3/7/2024 | $221,250 |
| | 2024 | 2024 | Children's Hospital Corporation, The | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | 90YE0303 | California Tribal Evaluation of Child Care and Development Fund Policies and Initiatives Implementation | 01 | 1 | ACF | 11/22/2023 | $300,000 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HG012871 | An ensemble framework for regulatory variant prediction. | 000 | 2 | NIH | 2/27/2024 | $508,990 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | UH3HL157564 | A Phase III Randomized Trial Comparing Unrelated Donor Bone Marrow Transplantation with Immune Suppressive Therapy for Newly Diagnosed Pediatric and Young Adult Patients with Severe Aplastic Anemia | 001 | 3 | NIH | 3/22/2024 | $636,067 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD107060 | Inflammatory stressors in serotonergic brainstem dysfunction and SIDS | 000 | 2 | NIH | 3/19/2024 | $650,415 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL158192 | High resolution lineage tracing of developmental hematopoiesis | 000 | 2 | NIH | 2/12/2024 | $675,723 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21EY033550 | Novel growth factors and regenerative RGC subtypes for optic nerve regeneration | 000 | 2 | NIH | 4/12/2024 | $221,250 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI177778 | Elucidating the functional mechanism of NLRP3 inflammasome activation | 000 | 2 | NIH | 2/21/2024 | $637,200 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AR082609 | Conditional mouse models with dominant negative Osteogenesis Imperfecta | 000 | 2 | NIH | 4/2/2024 | $175,230 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01DK134647 | The Role of Tcf7l2 in maintaining liver zonation and metabolic homeostasis | 000 | 2 | NIH | 1/10/2024 | $423,613 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI175556 | Mechanisms of enhanced food allergy by S. aureus skin colonization in Atopic Dermatitis | 000 | 2 | NIH | 2/23/2024 | $703,266 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21CA277460 | Tumor-targeted disruption of mismatch repair in microsatellite stable colorectal cancer | 001 | 2 | NIH | 4/17/2024 | $10,342 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21CA277460 | Tumor-targeted disruption of mismatch repair in microsatellite stable colorectal cancer | 000 | 2 | NIH | 11/13/2023 | $186,183 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K08NS130150 | The Role of Fos and the BAF Complex in Neuronal Activity-Dependent Chromatin Remodeling and Gene Expression | 000 | 2 | NIH | 4/1/2024 | $192,020 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL167513 | Targeting ZNF410 for HbF reactivation | 000 | 2 | NIH | 3/7/2024 | $605,162 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R35HL166556 | Inflammation and thrombosis fuel cardiovascular and pulmonary disease: Focus on the interplay of neutrophil inflammasomes with NETs | 000 | 2 | NIH | 3/5/2024 | $1,115,101 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01GM149729 | Gene Expression Modulated by G4, R-loop and DNA Supercoiling | 002 | 3 | NIH | 3/4/2024 | $318,600 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD110772 | Accurate, reliable, and interpretable machine learning for assessment of neonatal and pediatric brain micro-structure | 001 | 2 | NIH | 2/22/2024 | $0 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD110772 | Accurate, reliable, and interpretable machine learning for assessment of neonatal and pediatric brain micro-structure | 000 | 2 | NIH | 1/25/2024 | $342,495 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01MH130356 | Effects of 16p11.2 copy number variation on neuronal development and pathology | 000 | 2 | NIH | 2/5/2024 | $749,529 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AI173596 | Improving mRNA vaccines with extracellular vesicle-associated immunogens | 002 | 3 | NIH | 12/26/2023 | $199,125 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AI173596 | Improving mRNA vaccines with extracellular vesicle-associated immunogens | 000 | 3 | NIH | 11/1/2023 | $199,125 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K01DA057374 | Mobile health applications in adolescent marijuana use: assessing the interplay among sleep, pain and inhibitory control - Supplement | 001 | 2 | NIH | 12/22/2023 | $75,579 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K01DA057374 | Mobile health applications in adolescent marijuana use: assessing the interplay among sleep, pain and inhibitory control - Supplement | 000 | 2 | NIH | 11/16/2023 | $179,189 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K00NS120596 | The Development of Facial Motor Neuron Subtypes in Health and in Congenital Facial Weakness | 001 | 4 | NIH | 2/9/2024 | $5,910 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K00NS120596 | The Development of Facial Motor Neuron Subtypes in Health and in Congenital Facial Weakness | 000 | 4 | NIH | 12/19/2023 | $86,065 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | UG3NS132138 | Development of an Efficient High Throughput Technique for the Identification of High-Impact Non-Coding Somatic Variants Across Multiple Tissue Types | 000 | 2 | NIH | 4/23/2024 | $422,067 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AI173596 | Improving mRNA vaccines with extracellular vesicle-associated immunogens | 002 | 3 | NIH | 12/26/2023 | -$199,125 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01NS129823 | Targeting the Choroid Plexus-Cerebrospinal Fluid System to Treat Post-Hemorrhagic Hydrocephalus | 002 | 2 | NIH | 4/9/2024 | $40,794 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01NS129823 | Targeting the Choroid Plexus-Cerebrospinal Fluid System to Treat Post-Hemorrhagic Hydrocephalus | 001 | 2 | NIH | 12/28/2023 | $65,297 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL161605 | Glypicans in Bacterial Lung Infection | 000 | 1 | NIH | 4/1/2024 | $561,478 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01EY036220 | Promoting myelination of regenerating axons for vision restoration | 000 | 1 | NIH | 4/4/2024 | $560,851 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99HL173573 | The molecular determinants of atrial fibrillation | 000 | 1 | NIH | 3/28/2024 | $122,839 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R00NS126725 | Dissecting Hypothalamic Pathways for Seizure Control | 001 | 3 | NIH | 4/9/2024 | -$248,998 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R00NS126725 | Dissecting Hypothalamic Pathways for Seizure Control | 001 | 3 | NIH | 4/9/2024 | $241,529 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R00NS126725 | Dissecting Hypothalamic Pathways for Seizure Control | 000 | 3 | NIH | 2/29/2024 | $248,998 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R00CA267477 | Countering E-cigarette Marketing in the Retail Environment among Adolescents and Young Adults | 001 | 3 | NIH | 4/5/2024 | -$224,071 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL171405 | Pericyte contribution to capillary remodeling in pulmonary arterial hypertension | 000 | 1 | NIH | 12/15/2023 | $725,514 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R00CA267477 | Countering E-cigarette Marketing in the Retail Environment among Adolescents and Young Adults | 001 | 3 | NIH | 4/5/2024 | $248,968 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R00CA267477 | Countering E-cigarette Marketing in the Retail Environment among Adolescents and Young Adults | 000 | 3 | NIH | 2/29/2024 | $224,071 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01EB034757 | Low-dose contrast enhanced fast pediatric brain MRI | 000 | 1 | NIH | 3/1/2024 | $545,716 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01EY034846 | Development of Oculomotor Circuits in Nystagmus | 000 | 1 | NIH | 12/15/2023 | $442,500 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99HL169927 | Deciphering the intrinsic myocardial and/or endocardial defects of hypoplastic left heart syndrome | 000 | 1 | NIH | 2/29/2024 | $127,278 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD112379 | Metabolic control of the neural crest epigenome | 000 | 1 | NIH | 2/28/2024 | $560,550 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01CA287076 | Activating gasdermin pores to induce pyroptosis and stimulate anti-tumor immunity | 000 | 1 | NIH | 4/4/2024 | $733,069 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01DE033701 | Architecture and function of the neural crest genome | 000 | 1 | NIH | 3/27/2024 | $554,035 |
| | 2024 | 2024 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01EY035684 | Kinase regulators of retinal ganglion cell survival and axon regeneration | 000 | 1 | NIH | 11/21/2023 | $652,092 |
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