| | | | | | | | | | | | | | | | |
| | |
 | Issue Date FY: 2025 ( Subtotal = $270,235,691 ) (Continued on the next page) |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R56HD119040 | Trends and inEquities through Real-time Injury Surveillance (TETRIS): Novel Use of Physician-Informed Natural Language Processing in Emergency Department Data for Pediatric Injury Surveillance | 000 | 1 | NIH | 8/14/2025 | $995,612 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21HL181712 | Time to ROSC as a Novel Outcome for Pediatric Cardiac Arrest Trials | 000 | 1 | NIH | 8/28/2025 | $279,644 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD119407 | Motion-Robust Iron Quantification of Newborn Brains using Radial MRI | 000 | 1 | NIH | 8/25/2025 | $584,406 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R56HD115763 | Genetic and Developmental Basis for Coordinated Growth of the Limb | 000 | 1 | NIH | 8/27/2025 | $674,620 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI112652 | Global regulators converge to orchestrate metabolism, biofilm, and pathogenesis | 000 | 9 | NIH | 2/13/2025 | $577,362 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL181969 | Optimizing HCT Outcomes: A Multi-omic Investigation | 000 | 1 | NIH | 8/11/2025 | $2,024,340 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI187854 | Mechanism of inflammation in deficiency of adenosine deaminase 2 | 000 | 1 | NIH | 7/23/2025 | $522,524 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AI188071 | Overcoming obstacles in structural elucidation of B cell antigen receptor assembly and lateral interaction | 000 | 1 | NIH | 7/9/2025 | $489,500 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99EY037374 | Transformations of photic information in melanopsin pathways | 000 | 1 | NIH | 7/1/2025 | $136,512 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R03HL174665 | Multimodal Characterization of Cardiac-Neurodevelopmental Genes | 000 | 1 | NIH | 7/16/2025 | $267,000 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99HG013662 | Computational Technology for Single-Cell Functional Genomics | 000 | 1 | NIH | 7/1/2025 | $130,680 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K08AG086586 | Elucidating the neuronal mechanisms underlying cognitive resilience to Alzheimer's Disease | 001 | 1 | NIH | 9/2/2025 | $0 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD091142 | Natural History of Succinic Semialdehyde Dehydrogenase Deficiency (SSADHD), a Heritable Disorder of GABA Metabolism | 002 | 7 | NIH | 8/25/2025 | $649,604 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K08AG086586 | Elucidating the neuronal mechanisms underlying cognitive resilience to Alzheimer's Disease | 000 | 1 | NIH | 8/8/2025 | $167,940 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01EY031715 | G protein-coupled receptor regulation of transcriptional mechanisms in the retinal vasculature. | 000 | 5 | NIH | 3/20/2025 | $475,344 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01DK123694 | Rosettes in Adrenal Development, Maintenance and Disease | 001 | 7 | NIH | 6/24/2025 | $755,828 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21DC022258 | Language Profiles and Outcomes in School-Age Children Diagnosed with Autism Spectrum Disorder as Toddlers | 000 | 1 | NIH | 8/12/2025 | $507,540 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI181618 | HIV-1 membrane fusion and inhibition | 000 | 2 | NIH | 3/18/2025 | $752,675 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99AI190055 | Dissecting the Molecular Mechanisms of NLRP3 Inflammasome Activation and Regulation. | 000 | 1 | NIH | 8/12/2025 | $122,472 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | T32HD098061 | Neonatal Research Training Program | 003 | 7 | NIH | 5/29/2025 | $8,568 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI192655 | Mechanisms of control of allergic skin inflammation by T regulatory cells | 000 | 1 | NIH | 7/23/2025 | $716,281 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R35CA305089 | Effect of tumor editing on antitumor immunity | 000 | 1 | NIH | 7/3/2025 | $901,205 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | T32HD098061 | Neonatal Research Training Program | 002 | 7 | NIH | 4/11/2025 | $591,193 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | OT2OD040407 | Integrating Genetic and Environmental Data to Predict Autism Susceptibility and Heterogeneity in the SPARK Cohort | 000 | 1 | NIH | 9/19/2025 | $1,127,167 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | OT2OD040407 | Integrating Genetic and Environmental Data to Predict Autism Susceptibility and Heterogeneity in the SPARK Cohort | 001 | 1 | NIH | 9/26/2025 | $3,121,982 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | F32GM161099 | Molecular mechanism of polyamines on DNA dynamics during DNA repair | 001 | 1 | NIH | 9/3/2025 | $0 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | F32GM161099 | Molecular mechanism of polyamines on DNA dynamics during DNA repair | 000 | 1 | NIH | 9/3/2025 | $77,752 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99DK143300 | Role of lipoxygenase-derived lipid mediators in the hematopoietic niche | 000 | 1 | NIH | 9/2/2025 | $90,000 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01DK139157 | Role of Lipogenic Pathways in Intestinal Remodeling after Gastric Bypass Surgery | 000 | 1 | NIH | 9/3/2025 | $3,103,125 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL181046 | Investigating pulmonary ionocyte function and development using iPSCs | 000 | 1 | NIH | 9/11/2025 | $809,162 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01DK143991 | Stress Granules in Red Blood Cell Development | 000 | 1 | NIH | 9/10/2025 | $801,000 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21DK142111 | Transformation of a human iPSC-derived bone marrow organoid for the study of hematopoiesis | 000 | 1 | NIH | 8/29/2025 | $469,042 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL179094 | Radon Asthma Intervention Trial (ROME) | 000 | 1 | NIH | 9/11/2025 | $784,318 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD119047 | Mental and Behavioral Health Among Vulnerable Adolescents and Young Adults in the United States | 000 | 1 | NIH | 9/5/2025 | $787,154 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01EB037186 | Motion and distortion-robust quantitative MRI of early brain developments | 001 | 1 | NIH | 8/27/2025 | $0 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01EB037186 | Motion and distortion-robust quantitative MRI of early brain developments | 000 | 1 | NIH | 7/29/2025 | $511,583 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | U01NS142013 | FAST-ET: Fast Automated Serial Tape-Enabled Electron Tomography | 000 | 1 | NIH | 7/31/2025 | $4,095,511 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | RF1AG093462 | Genetics of exceptional resilience and its variation; insights from the world's longest-lived animal | 000 | 1 | NIH | 8/4/2025 | $1,875,196 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL167513 | Targeting ZNF410 for HbF reactivation | 001 | 3 | NIH | 8/19/2025 | $67,241 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL167513 | Targeting ZNF410 for HbF reactivation | 000 | 3 | NIH | 2/28/2025 | $605,162 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | U01AI191995 | Phase 1 study of a SARS-CoV-2 vaccine adjuvanted via controlled biodistribution of mRNA encoding spike protein and IL-12p70 | 000 | 1 | NIH | 9/25/2025 | $1,673,641 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI175556 | Mechanisms of enhanced food allergy by S. aureus skin colonization in Atopic Dermatitis | 000 | 3 | NIH | 2/12/2025 | $757,963 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01CA295865 | Evaluating Pathways Involved in Melanoma Initiation | 000 | 1 | NIH | 7/29/2025 | $679,604 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01MH130356 | Effects of 16p11.2 copy number variation on neuronal development and pathology | 000 | 3 | NIH | 2/19/2025 | $699,666 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AI180611 | C. albicans cell wall stress responses and TOR signaling | 000 | 1 | NIH | 7/28/2025 | $489,500 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL176663 | Investigating the pro-regenerative potential of Pontin in the heart. | 000 | 1 | NIH | 7/30/2025 | $833,594 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K01NS142019 | Role of KMT2D in neurodevelopmental disorders | 000 | 1 | NIH | 8/6/2025 | $241,380 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | F32GM159374 | Investigating BMAL1-RNA interactions and their roles in circadian rhythms | 001 | 1 | NIH | 7/25/2025 | $0 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | F32GM159374 | Investigating BMAL1-RNA interactions and their roles in circadian rhythms | 000 | 1 | NIH | 7/25/2025 | $81,040 |
|
