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 | Issue Date FY: 2025 ( Subtotal = $270,235,691 ) (Continued on the next page) |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL096384 | Blood vessel assembly from multipotent hemangioma-derived stem cells | 002 | 14 | NIH | 4/14/2025 | $661,475 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01NS120986 | Predicting ASD and Other Developmental Outcomes in the First Year of Life Using EEG in a Diverse Community-Based Sample (Revision) | 001 | 4 | NIH | 5/16/2025 | $624,623 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01NS120986 | Predicting ASD and Other Developmental Outcomes in the First Year of Life Using EEG in a Diverse Community-Based Sample (Revision) | 000 | 4 | NIH | 2/13/2025 | $594,360 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01CA287076 | Activating gasdermin pores to induce pyroptosis and stimulate anti-tumor immunity | 001 | 2 | NIH | 5/22/2025 | $73,306 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01CA287076 | Activating gasdermin pores to induce pyroptosis and stimulate anti-tumor immunity | 000 | 2 | NIH | 3/3/2025 | $659,763 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | T32HD098061 | Neonatal Research Training Program | 003 | 7 | NIH | 5/29/2025 | $8,568 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | T32HD098061 | Neonatal Research Training Program | 004 | 7 | NIH | 5/30/2025 | $686 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI181618 | HIV-1 membrane fusion and inhibition | 000 | 2 | NIH | 3/18/2025 | $752,675 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R35CA305089 | Effect of tumor editing on antitumor immunity | 000 | 1 | NIH | 7/3/2025 | $901,205 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL181969 | Optimizing HCT Outcomes: A Multi-omic Investigation | 000 | 1 | NIH | 8/11/2025 | $2,024,340 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R56HD119040 | Trends and inEquities through Real-time Injury Surveillance (TETRIS): Novel Use of Physician-Informed Natural Language Processing in Emergency Department Data for Pediatric Injury Surveillance | 000 | 1 | NIH | 8/14/2025 | $995,612 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AI193598 | Cryo-ET structure of the Plasmodium basal complex | 000 | 1 | NIH | 8/4/2025 | $501,800 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21HL181712 | Time to ROSC as a Novel Outcome for Pediatric Cardiac Arrest Trials | 000 | 1 | NIH | 8/28/2025 | $279,644 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R56HD115763 | Genetic and Developmental Basis for Coordinated Growth of the Limb | 000 | 1 | NIH | 8/27/2025 | $674,620 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI112652 | Global regulators converge to orchestrate metabolism, biofilm, and pathogenesis | 000 | 9 | NIH | 2/13/2025 | $577,362 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD119407 | Motion-Robust Iron Quantification of Newborn Brains using Radial MRI | 000 | 1 | NIH | 8/25/2025 | $584,406 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | U01NS142013 | FAST-ET: Fast Automated Serial Tape-Enabled Electron Tomography | 000 | 1 | NIH | 7/31/2025 | $4,095,511 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | RF1AG093462 | Genetics of exceptional resilience and its variation; insights from the world's longest-lived animal | 000 | 1 | NIH | 8/4/2025 | $1,875,196 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01EB037186 | Motion and distortion-robust quantitative MRI of early brain developments | 001 | 1 | NIH | 8/27/2025 | $0 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01EB037186 | Motion and distortion-robust quantitative MRI of early brain developments | 000 | 1 | NIH | 7/29/2025 | $511,583 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI169648 | Functional investigation of a novel and essential subcellular compartment in Plasmodium falciparum transmission stage parasites | 000 | 4 | NIH | 2/18/2025 | $687,521 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | RF1NS142871 | Transposable Element Mobilization and Disrupted Translational Machinery in Down Syndrome | 000 | 1 | NIH | 7/30/2025 | $1,274,904 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL182042 | Developing a spatiotemporal lineage map of heart development | 000 | 1 | NIH | 7/24/2025 | $865,286 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K23DK127251 | Effect of Thickened Feeds on Swallow Physiology and Clinical Outcomes in Children with Brief Resolved Unexplained Event | 000 | 5 | NIH | 2/26/2025 | $194,940 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R13AR086669 | Development of a Pediatric Rheumatology Common Data Element set (CDE) for Juvenile Idiopathic Arthritis | 000 | 1 | NIH | 7/24/2025 | $1 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AI185295 | Unravelling the role of aDb2 as a novel complement receptor in lung injury | 000 | 1 | NIH | 7/23/2025 | $489,500 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R13AR086669 | Development of a Pediatric Rheumatology Common Data Element set (CDE) for Juvenile Idiopathic Arthritis | 000 | 1 | NIH | 7/24/2025 | $74,833 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AI194232 | Human cellular models of TB and innate immunity | 000 | 1 | NIH | 7/23/2025 | $489,500 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K01NS142019 | Role of KMT2D in neurodevelopmental disorders | 000 | 1 | NIH | 8/6/2025 | $241,380 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AI180611 | C. albicans cell wall stress responses and TOR signaling | 000 | 1 | NIH | 7/28/2025 | $489,500 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL176663 | Investigating the pro-regenerative potential of Pontin in the heart. | 000 | 1 | NIH | 7/30/2025 | $833,594 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | F32GM159374 | Investigating BMAL1-RNA interactions and their roles in circadian rhythms | 001 | 1 | NIH | 7/25/2025 | $0 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AI180552 | Structural studies of the full-length nucleocapsid protein of SARS-CoV-2 | 000 | 1 | NIH | 7/23/2025 | $489,500 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | F32GM159374 | Investigating BMAL1-RNA interactions and their roles in circadian rhythms | 000 | 1 | NIH | 7/25/2025 | $81,040 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI182177 | Armed nanobodies as anti-infectives and anti-tumor agents | 001 | 2 | NIH | 5/23/2025 | $299,967 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI182177 | Armed nanobodies as anti-infectives and anti-tumor agents | 001 | 2 | NIH | 5/23/2025 | $242,933 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R37NS109211 | Kinetochore Protein Functions in Synaptogenesis | 002 | 7 | NIH | 8/4/2025 | $619,447 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI175556 | Mechanisms of enhanced food allergy by S. aureus skin colonization in Atopic Dermatitis | 000 | 3 | NIH | 2/12/2025 | $757,963 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01MH130356 | Effects of 16p11.2 copy number variation on neuronal development and pathology | 000 | 3 | NIH | 2/19/2025 | $699,666 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | F32HL182158 | Additive Therapeutic Efficacy Of Pluripotent Stem Cell-Derived Cardiovascular Cells Engrafted In Hydrogels To Treat Ischemia-Reperfusion Injury After Myocardial Infarction | 001 | 1 | NIH | 8/15/2025 | $0 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | F32HL182158 | Additive Therapeutic Efficacy Of Pluripotent Stem Cell-Derived Cardiovascular Cells Engrafted In Hydrogels To Treat Ischemia-Reperfusion Injury After Myocardial Infarction | 000 | 1 | NIH | 8/15/2025 | $88,434 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL158192 | High resolution lineage tracing of developmental hematopoiesis | 000 | 3 | NIH | 3/6/2025 | $668,787 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL158192 | High resolution lineage tracing of developmental hematopoiesis | 001 | 3 | NIH | 7/16/2025 | $74,310 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01CA295865 | Evaluating Pathways Involved in Melanoma Initiation | 000 | 1 | NIH | 7/29/2025 | $679,604 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | U01AI191995 | Phase 1 study of a SARS-CoV-2 vaccine adjuvanted via controlled biodistribution of mRNA encoding spike protein and IL-12p70 | 000 | 1 | NIH | 9/25/2025 | $1,673,641 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99MH136290 | Genomic approaches to understand human neural specializations | 001 | 2 | NIH | 8/21/2025 | -$74,261 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K00NS129126 | Epilepsy Mechanisms and the Path to Intervention | 001 | 3 | NIH | 9/24/2025 | $0 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99MH136290 | Genomic approaches to understand human neural specializations | 000 | 2 | NIH | 3/12/2025 | $127,305 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K00NS129126 | Epilepsy Mechanisms and the Path to Intervention | 000 | 3 | NIH | 8/13/2025 | $85,752 |
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