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 | Issue Date FY: 2023 ( Subtotal = $134,559,792 ) (Continued on the next page) |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R00CA262152 | A pan-cancer atlas of driver mutations in >100,000 patients based on a hypothesis-driven combined computational and experimental approach | 000 | 3 | NIH | 2/27/2023 | $214,480 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | UG3NS132138 | Development of an Efficient High Throughput Technique for the Identification of High-Impact Non-Coding Somatic Variants Across Multiple Tissue Types | 000 | 1 | NIH | 3/31/2023 | $448,340 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99HD110651 | Maternal stress and undernutrition: Interactive effects on newborn and child outcomes in Ethiopia? | 000 | 1 | NIH | 5/19/2023 | $132,489 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K01DA057374 | Mobile health applications in adolescent marijuana use: assessing the interplay among sleep, pain and inhibitory control | 000 | 1 | NIH | 12/23/2022 | $178,973 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL158192 | High resolution lineage tracing of developmental hematopoiesis | 000 | 1 | NIH | 5/5/2023 | $777,500 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21EY033550 | Novel growth factors and regenerative RGC subtypes for optic nerve regeneration | 000 | 1 | NIH | 4/20/2023 | $265,500 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01MH130356 | Effects of 16p11.2 copy number variation on neuronal development and pathology | 000 | 1 | NIH | 3/3/2023 | $861,572 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01NS128281 | Enabling the Assessment of Fetal Brain Development and Degeneration with Machine Learning | 000 | 1 | NIH | 5/24/2023 | $442,500 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD110772 | Accurate, reliable, and interpretable machine learning for assessment of neonatal and pediatric brain micro-structure | 000 | 1 | NIH | 4/6/2023 | $380,550 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01DK134647 | The Role of Tcf7l2 in maintaining liver zonation and metabolic homeostasis | 000 | 1 | NIH | 1/27/2023 | $465,289 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01GM148392 | CD11c as a novel target to improve neutrophil effector functions and sepsis outcome | 000 | 1 | NIH | 1/18/2023 | $389,400 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99DK134760 | Clonal dynamics of the blood stem cell niche | 000 | 1 | NIH | 2/7/2023 | $91,500 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21HD108634 | Machine learning Approaches to Radiological Dating of Infant Clavicle Fractures" | 000 | 1 | NIH | 11/23/2022 | $221,250 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01ES034713 | Interdisciplinary approaches for understanding how arsenic and micronutrients affect the epigenome to influence spina bifida risk | 000 | 1 | NIH | 1/19/2023 | $799,165 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R21AR082609 | Conditional mouse models with dominant negative Osteogenesis Imperfecta | 000 | 1 | NIH | 2/24/2023 | $233,640 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01NS129823 | Targeting the Choroid Plexus-Cerebrospinal Fluid System to Treat Post-Hemorrhagic Hydrocephalus | 000 | 1 | NIH | 12/15/2022 | $582,811 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL163513 | High-throughput Phenotyping of iPSC-derived Airway Epithelium by Multiscale Machine Learning Microscopy | 000 | 1 | NIH | 3/23/2023 | $781,190 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL167450 | Desmosomes in cardiomyocyte homeostasis and disease | 001 | 1 | NIH | 1/25/2023 | $0 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL167450 | Desmosomes in cardiomyocyte homeostasis and disease | 000 | 1 | NIH | 12/13/2022 | $816,496 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI175556 | Mechanisms of enhanced food allergy by S. aureus skin colonization in Atopic Dermatitis | 000 | 1 | NIH | 3/22/2023 | $800,145 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R03NS127044 | Combining Brain Connectivity and Excitability to Plan Epilepsy Surgery in Children: A New Approach to Augment Presurgical Intracranial Electroencephalography | 000 | 1 | NIH | 12/30/2022 | $88,500 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R56DK098655 | Hepatic insulin resistance integrates T2D and NAFLD | 000 | 9 | NIH | 3/30/2023 | $150,450 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R03NS127044 | Combining Brain Connectivity and Excitability to Plan Epilepsy Surgery in Children: A New Approach to Augment Presurgical Intracranial Electroencephalography | 001 | 1 | NIH | 1/20/2023 | $0 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | UG3NS132144 | Detection and Characterization of Somatic Mutations in Human Tissue Utilizing Duplex-Consensus Sequencing | 000 | 1 | NIH | 3/28/2023 | $442,498 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K08AI171176 | Lung resident Treg suppression of Th2 resident memory T cells in allergic asthma | 000 | 1 | NIH | 1/9/2023 | $194,775 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R35HL166556 | Inflammation and thrombosis fuel cardiovascular and pulmonary disease: Focus on the interplay of neutrophil inflammasomes with NETs | 000 | 1 | NIH | 3/15/2023 | $1,239,000 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL167513 | Targeting ZNF410 for HbF reactivation | 000 | 1 | NIH | 2/28/2023 | $691,653 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K00MH133546 | Role of glycosylation in environmental and genetic schizophrenia risk | 000 | 2 | NIH | 12/30/2022 | $86,065 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL163937 | CMYA5 regulation of cardiac dyad structure and function | 000 | 1 | NIH | 12/13/2022 | $614,602 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01NS124212 | Motion Compensated fMRI for Pre-Surgical Planning in Epilepsy | 000 | 1 | NIH | 5/2/2023 | $671,051 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | F32NS131252 | Determining the Impact of Callosal Connectivity on Visual Cortical Structure and Cortical Visual Impairment in Cdkl5 Deficiency Disorder | 001 | 1 | NIH | 2/15/2023 | $0 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL162642 | Balancing epithelial cell resistance and resilience to respiratory viral infections | 000 | 1 | NIH | 12/22/2022 | $869,852 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K08DK125768 | Delineation of pathogenic mechanisms of NOS1AP and TRIM8 mutations in monogenic SRNS/FSGS. | 000 | 3 | NIH | 3/23/2023 | $167,940 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL156362 | The role of signaling adaptor protein epsin in atherosclerosis | 001 | 3 | NIH | 2/11/2023 | $78,592 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K23MH120510 | The neuroanatomical basis for face processing deficits in autism spectrum disorder | 000 | 4 | NIH | 4/11/2023 | $195,005 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K23DC017983 | Neural Markers of Language Development in Fragile X Syndrome and Autism Spectrum Disorder | 000 | 4 | NIH | 3/22/2023 | $171,804 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01DK125561 | Robust quantitative MR imaging markers of response to therapy in Crohn?s Disease | 000 | 3 | NIH | 1/24/2023 | $398,250 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL156362 | The role of signaling adaptor protein epsin in atherosclerosis | 000 | 3 | NIH | 11/14/2022 | $707,330 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AG067913 | Regulation of hippocampal function by central and peripheral IRS signaling | 000 | 4 | NIH | 1/25/2023 | $620,229 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R35GM141794 | Microbial Modulation of Physiology and Behavior of C. elegans | 000 | 3 | NIH | 3/22/2023 | $442,500 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AG070921 | Rates and mechanisms of age-related somatic mutation in normal and Alzheimer brain | 000 | 3 | NIH | 3/22/2023 | $853,949 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K23HL148539 | Cardiovascular health assessment & outcomes of systemic lupus erythematosus: bridging pediatric and adult- onset disease | 000 | 4 | NIH | 5/19/2023 | $175,866 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | T2537594 | Addiction Medicine Fellowship | 00 | 4 | HRSA | 5/2/2023 | $798,242 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL151368 | Investigating Circadian Mechanisms of Cellular Resilience: Rhythmic Condensates, Disorder, and Stress | 000 | 4 | NIH | 4/20/2023 | $418,801 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K08AR078370 | Translating Human Height Genetics to Skeletal Biology by Functional Genomics of the Growth Plate | 000 | 3 | NIH | 5/9/2023 | $173,340 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K23AI155940 | Function of RELM? in oral tolerance breakdown in food allergy | 000 | 3 | NIH | 5/19/2023 | $194,940 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL152358 | Exploring the relationship between advanced multimodal brain MRI phenotypes, genes and cognitive outcome in adults with CHD | 000 | 3 | NIH | 1/23/2023 | $782,619 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI158814 | Targeting microbial dysbiosis in Food Allergy to restore tolerance | 000 | 3 | NIH | 1/23/2023 | $601,609 |
| | 2023 | 2023 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K08NS123552 | Development of a Translational Research Platform to Understand and treat Defective Protein Trafficking in Childhood-Onset Hereditary Spastic Paraplegia | 000 | 3 | NIH | 4/20/2023 | $231,255 |
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