| | | | | | | | | | | | | | | | |
| | |
 | Issue Date FY: 2025 ( Subtotal = $74,038,508 ) (Continued on the next page) |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99MH136290 | Genomic approaches to understand human neural specializations | 000 | 2 | NIH | 3/12/2025 | $127,305 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R37NS035129 | Human Epilepsy Genetics - Mosaic Mutations in Focal Epilepsy | 001 | 26 | NIH | 3/20/2025 | -$26,722 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | U01AI181964 | Consortium for food allergy research clinical center CoFar | 000 | 2 | NIH | 4/1/2025 | $380,000 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01EY033025 | ECM Regulation of Ocular Surface Disease | 000 | 4 | NIH | 3/20/2025 | $442,500 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01EY031715 | G protein-coupled receptor regulation of transcriptional mechanisms in the retinal vasculature. | 000 | 5 | NIH | 3/20/2025 | $475,344 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K01DK129409 | Mechanisms of Flow-driven Transcriptional Control of Hematopoietic Stem Cell Development by YAP | 000 | 5 | NIH | 3/28/2025 | $153,046 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD107060 | Inflammatory stressors in serotonergic brainstem dysfunction and SIDS | 000 | 3 | NIH | 4/2/2025 | $723,152 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD114338 | Developing novel MR tools to optimize surgical planning and fetal outcome in TTTS | 000 | 2 | NIH | 4/2/2025 | $717,249 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K08DK125768 | Delineation of pathogenic mechanisms of NOS1AP and TRIM8 mutations in monogenic SRNS/FSGS. | 000 | 5 | NIH | 3/28/2025 | $167,940 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | U19AI168643 | Immune development in early life (IDEAL) shapes vaccine response, respiratory infectious diseaseand asthma | 001 | 4 | NIH | 3/19/2025 | $1,534,027 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL167723 | Sphingolipid signaling in the endothelium during viral host defense | 000 | 2 | NIH | 1/10/2025 | $623,678 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD110772 | Accurate, reliable, and interpretable machine learning for assessment of neonatal and pediatric brain micro-structure | 000 | 3 | NIH | 1/9/2025 | $342,495 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99HL169927 | Deciphering the intrinsic myocardial and/or endocardial defects of hypoplastic left heart syndrome | 000 | 2 | NIH | 2/21/2025 | $127,278 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01CA196703 | Mechanisms of resistance to ALK inhibitors in ALK-rearranged lymphoma | 000 | 10 | NIH | 2/17/2025 | $378,338 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R35GM141794 | Microbial Modulation of Physiology and Behavior of C. elegans | 001 | 5 | NIH | 3/21/2025 | $398,250 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL096384 | Blood vessel assembly from multipotent hemangioma-derived stem cells | 002 | 14 | NIH | 4/14/2025 | $661,475 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K08AI187736 | The Establishment of Lung Resident Self-Antigen-Specific CD4+ Tregs Following Acute Tissue injury | 000 | 1 | NIH | 2/24/2025 | $194,740 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | T32HD098061 | Neonatal Research Training Program | 002 | 7 | NIH | 4/11/2025 | $591,193 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | T32HD040128 | Research Training in Pediatric Emergency Medicine | 003 | 22 | NIH | 4/11/2025 | $451,788 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | U01AI160087 | Novel NOTCH4 Pathway of Asthma Severity in Urban School Children: Clinical Research Center, Boston Children’s Hospital | 000 | 5 | NIH | 4/11/2025 | $1 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K23MD016171 | Developing an engagement intervention for Black and Latinx caregivers to improve children’s receipt of mental health services after sexual abuse | 000 | 4 | NIH | 2/18/2025 | $151,146 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI169648 | Functional investigation of a novel and essential subcellular compartment in Plasmodium falciparum transmission stage parasites | 000 | 4 | NIH | 2/18/2025 | $687,521 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AI189786 | Characterization of a novel post-transcriptional regulator in P. aeruginosa | 000 | 1 | NIH | 2/25/2025 | $868,776 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K08AR080992 | Development of resident memory T cells in the synovium | 000 | 4 | NIH | 4/11/2025 | $173,340 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL158192 | High resolution lineage tracing of developmental hematopoiesis | 000 | 3 | NIH | 3/6/2025 | $668,787 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | UH3HL157564 | A Phase III Randomized Trial Comparing Unrelated Donor Bone Marrow Transplantation with Immune Suppressive Therapy for Newly Diagnosed Pediatric and Young Adult Patients with Severe Aplastic Anemia | 003 | 4 | NIH | 3/27/2025 | $634,334 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K12HD052896 | Child Health Research Career Development Award (CHRCDA) Program (K12) | 001 | 18 | NIH | 3/6/2025 | $0 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HD116750 | Understanding the mechanism of pre- to naïve- to formative- pluripotency transitions | 000 | 1 | NIH | 4/4/2025 | $760,617 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AG078423 | Shared Genetic and Environmental Influences on Age-Related Hearing Loss, Cognitive Decline, and Dementia Risk | 000 | 3 | NIH | 4/4/2025 | $656,205 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R35HL150876 | Cell-cell interactions governing lung epithelial progenitor cells | 000 | 6 | NIH | 3/27/2025 | $796,500 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K99AR083482 | Elucidating the neuroimmune mechanisms underlying pain and inflammation in autoimmune arthritis (Admin Supplement) | 000 | 1 | NIH | 4/4/2025 | $75,600 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AR073201 | Bridging the gap between GWAS and mechanism in arthritis | 001 | 6 | NIH | 4/10/2025 | $633,297 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01GM149729 | Gene Expression Modulated by G4, R-loop and DNA Supercoiling | 000 | 4 | NIH | 2/19/2025 | $318,600 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01NS107490 | Axonal Transport of mRNA for Mitochondrial Proteins | 001 | 7 | NIH | 4/9/2025 | $578,845 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K23DK127251 | Effect of Thickened Feeds on Swallow Physiology and Clinical Outcomes in Children with Brief Resolved Unexplained Event | 000 | 5 | NIH | 2/26/2025 | $194,940 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL172968 | A Novel Transcription Factor-Driven Approach for Mural Progenitor Cells Generation | 000 | 2 | NIH | 4/10/2025 | $574,306 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01EY036220 | Promoting myelination of regenerating axons for vision restoration | 000 | 2 | NIH | 4/10/2025 | $560,851 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01EY032492 | Serine control of retinal neovascularization in retinopathy | 000 | 5 | NIH | 4/10/2025 | $442,500 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | U01AI125051 | Gene therapy for SCID-X1 with low dose busulfan and a SIN-lentiviral vector | 002 | 8 | NIH | 2/19/2025 | $894,481 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01CA255216 | Non-invasive imaging of the anti-tumor immune response | 001 | 5 | NIH | 2/19/2025 | $0 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K01DK124443 | Blocking Latent TGF-β2 Activation as a Therapeutic Strategy for Renal Fibrosis | 000 | 5 | NIH | 4/9/2025 | $153,846 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL152358 | Exploring the relationship between advanced multimodal brain MRI phenotypes, genes and cognitive outcome in adults with CHD | 000 | 5 | NIH | 2/15/2025 | $704,328 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01DA050589 | Understanding neuronal subtype-specific function of NAc in cocaine addiction | 000 | 5 | NIH | 2/28/2025 | $650,703 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01EB034757 | Low-dose contrast enhanced fast pediatric brain MRI | 000 | 2 | NIH | 3/24/2025 | $536,405 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R00NS126725 | Dissecting Hypothalamic Pathways for Seizure Control | 000 | 4 | NIH | 2/14/2025 | $224,098 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL171206 | Mechanistic dissection of 22q11.2DS in zebrafish | 000 | 2 | NIH | 2/28/2025 | $559,110 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01HL167513 | Targeting ZNF410 for HbF reactivation | 000 | 3 | NIH | 2/28/2025 | $605,162 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | R01AG070921 | Rates and mechanisms of age-related somatic mutation in normal and Alzheimer brain | 000 | 5 | NIH | 3/24/2025 | $743,704 |
| | 2025 | 2025 | CHILDREN'S HOSPITAL CORPORATION, THE | 300 LONGWOOD AVE | BOSTON | MA | 02115-5724 | SUFFOLK | USA | K08HL173561 | Endothelial cell-based therapy for pulmonary vascular disease using induced pluripotent stem cells | 000 | 2 | NIH | 2/28/2025 | $167,940 |
|
