Wednesday, December 31, 2025 12/31/2025

Mathematical, Computational and Systems Biology

Award Number: T32GM136624
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 07/01/2020
PERIOD OF PERFORMANCE END DATE: 06/30/2025

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Mathematical, Computational and Systems Biology - Program Summary/Abstract In recent years, new demands are being placed on biomedical researchers and clinicians thanks to changes in the way we acquire, analyze and interact with data. Many areas of biomedical science are transitioning from being data-poor and hypothesis-rich to extremely data-rich and (comparatively) hypothesis-poor. Conducting rigorous research in this new environment can be challenging, as it requires grounding not just in biology, but also in mathematics, computation and statistics. This application requests support for a pre-doctoral training program designed to produce Ph.D.s with sufficient skills in fundamental biology, mathematical and computational modeling, and data science to attack these challenges head on. The program is built upon a free-standing, interdisciplinary Ph.D. program that has been developed and refined over the past dozen years, and offers training at the interface between the biological sciences and mathematics, computer science, physics and engineering. Eight pre- doctoral trainee slots are requested, for appointments intended to last two years each. Highlights of the proposed program include an extensive didactic curriculum; a focus on critical thinking skills; an emphasis on collaboration and collaborative learning; close mentoring, opportunities to develop multiple career skills; and active student involvement. The 31 program faculty members come from 14 different departments in five schools at the University of California, Irvine, and conduct research on diverse topics within biology and medicine. The program enjoys strong campus support, and an administrative and intellectual home within the UCI Center for Complex Biological Systems, a National Center for Systems Biology with a long- standing commitment to promoting interdisciplinary education at all academic levels. The proposed program will prepare trainees for careers in biomedical research, teaching, and communication in both academic and non-academic settings.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2024	UNIVERSITY OF CALIFORNIA IRVINE	160 ALDRICH HALL	IRVINE	CA	92697	ORANGE	USA	Biomedical Research and Research Training	000	5	11/18/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2025 ( Subtotal = $505,410 )
2025	2025	UNIVERSITY OF CALIFORNIA IRVINE	160 ALDRICH HALL	IRVINE	CA	92697	ORANGE	USA	Biomedical Research and Research Training	000	6	6/18/2025	COMPETING CONTINUATION	$505,410
														Subtotal = $505,410

Issue Date FY: 2024 ( Subtotal = $319,250 )
2024	2024	UNIVERSITY OF CALIFORNIA IRVINE	160 ALDRICH HALL	IRVINE	CA	92697	ORANGE	USA	Biomedical Research and Research Training	000	5	6/12/2024	NON-COMPETING CONTINUATION	$319,250
														Subtotal = $319,250

Issue Date FY: 2023 ( Subtotal = $361,924 )
2023	2023	UNIVERSITY OF CALIFORNIA, IRVINE	160 ALDRICH HALL	IRVINE	CA	92697	ORANGE	USA	Biomedical Research and Research Training	000	4	6/29/2023	NON-COMPETING CONTINUATION	$361,924
														Subtotal = $361,924

Issue Date FY: 2022 ( Subtotal = $463,082 )
2022	2022	UNIVERSITY OF CALIFORNIA, IRVINE	141 INNOVATION DR STE 250	IRVINE	CA	92617	ORANGE	USA	Biomedical Research and Research Training	000	3	6/10/2022	NON-COMPETING CONTINUATION	$463,082
														Subtotal = $463,082

Issue Date FY: 2021 ( Subtotal = $516,722 )
2021	2021	UNIVERSITY OF CALIFORNIA, IRVINE	141 INNOVATION DR STE 250	IRVINE	CA	92617	ORANGE	USA	Biomedical Research and Research Training	000	2	6/15/2021	NON-COMPETING CONTINUATION	$430,349
2021	2021	UNIVERSITY OF CALIFORNIA, IRVINE	141 INNOVATION DR STE 250	IRVINE	CA	92617	ORANGE	USA	Biomedical Research and Research Training	001	2	6/25/2021	SUPPLEMENT FOR EXPANSION	$86,373
														Subtotal = $516,722

Issue Date FY: 2020 ( Subtotal = $382,295 )
2020	2020	UNIVERSITY OF CALIFORNIA, IRVINE	141 INNOVATION DR STE 250	IRVINE	CA	92617	ORANGE	USA	Biomedical Research and Research Training	000	1	5/27/2020	NEW	$382,295
														Subtotal = $382,295

Grand Total All Awards = $2,548,683

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Mathematical, Computational and Systems Biology

Award Number: T32GM136624

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 07/01/2020

PERIOD OF PERFORMANCE END DATE: 06/30/2025

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