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 | Issue Date FY: 2025 ( Subtotal = $94,478,638 ) (Continued on the next page) |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01DE033732 | Impact of Pregnancy Dental Benefits on Dental Care Utilization among Pregnant Women and Young Children | 001 | 2 | NIH | 5/8/2025 | $44,899 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01DE033732 | Impact of Pregnancy Dental Benefits on Dental Care Utilization among Pregnant Women and Young Children | 000 | 2 | NIH | 3/26/2025 | $404,095 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AG068992 | Cell autonomous and non-cell autonomous phenotypes due to genetic risk for late onset Alzheimers disease | 000 | 3 | NIH | 4/8/2025 | $650,726 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R21AI181315 | Role of TREM2 in host defense and immunity during infection | 000 | 2 | NIH | 4/24/2025 | $188,300 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R21AI178613 | Larval Ecology of Invasive Anopheles stephensi in Ethiopia | 000 | 2 | NIH | 12/3/2024 | $215,127 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R00HD100593 | Fetal Programming of Human Newborn Energy Homeostasis Brain Networks | 001 | 5 | NIH | 4/11/2025 | $24,900 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R00HD100593 | Fetal Programming of Human Newborn Energy Homeostasis Brain Networks | 000 | 5 | NIH | 1/8/2025 | $224,100 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AI158503 | Developing broad-spectrum therapeutics against C. difficile toxins | 000 | 5 | NIH | 1/10/2025 | $748,253 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01DA055849 | Ventral Pallidum Circuits Underlying Preclinical Models of Opioid Addiction | 001 | 3 | NIH | 4/9/2025 | $35,325 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01DA055849 | Ventral Pallidum Circuits Underlying Preclinical Models of Opioid Addiction | 000 | 3 | NIH | 1/17/2025 | $317,925 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R21TR005032 | Autonomous Platform for Pulsatile Soluble Stimulation | 000 | 2 | NIH | 3/13/2025 | $211,950 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AG082127 | Single-cell transcriptomic and epigenomic analysis of brain cell vulnerabilities to tauopathies in early AD impacted brain regions | 002 | 3 | NIH | 6/9/2025 | $161,589 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AG082127 | Single-cell transcriptomic and epigenomic analysis of brain cell vulnerabilities to tauopathies in early AD impacted brain regions | 001 | 3 | NIH | 3/7/2025 | $1,817,870 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | T32AR083870 | MAXIMUS: MAXimizing Training in MUScle Research | 000 | 2 | NIH | 6/5/2025 | $202,625 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01MH126285 | Nucleus accumbens circuits for regulating cue-motivated behavior | 000 | 5 | NIH | 3/11/2025 | $540,053 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R37CA266042 | Defining the Mechanism of Genome Rearrangements in Ph-Like ALL to Determine Predictive Markers in High-Risk Hispanic Populations | 003 | 4 | NIH | 5/22/2025 | $40,684 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R37CA266042 | Defining the Mechanism of Genome Rearrangements in Ph-Like ALL to Determine Predictive Markers in High-Risk Hispanic Populations | 002 | 4 | NIH | 4/10/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R37CA266042 | Defining the Mechanism of Genome Rearrangements in Ph-Like ALL to Determine Predictive Markers in High-Risk Hispanic Populations | 001 | 4 | NIH | 3/12/2025 | $366,163 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM153231 | Development of new methods and strategies for the synthesis of complex molecules | 001 | 2 | NIH | 1/8/2025 | $336,303 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM157311 | Defining the mechanisms that drive novel cyclic nucleotide signaling in immune defense | 000 | 1 | NIH | 1/31/2025 | $379,823 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AI185349 | The Role of Interferon Lambda in Alpha Herpesvirus Neuroinvasion | 000 | 1 | NIH | 1/27/2025 | $471,159 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01NS121227 | Mitochondrial Zn2+ accumulation and the induction of ischemic neurodegeneration | 000 | 4 | NIH | 12/23/2024 | $505,515 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01CA272680 | Effectiveness of Out-of-Pocket Cost COMmunication and Financial Navigation (CostCOM) in Cancer Patients | 001 | 3 | NIH | 6/2/2025 | $61,308 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01CA272680 | Effectiveness of Out-of-Pocket Cost COMmunication and Financial Navigation (CostCOM) in Cancer Patients | 000 | 3 | NIH | 12/6/2024 | $551,777 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F32HD114452 | Evaluating pain communication and understanding in interpreted medical encounters in a pediatric emergency department | 001 | 2 | NIH | 6/9/2025 | $1,224 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F32HD114452 | Evaluating pain communication and understanding in interpreted medical encounters in a pediatric emergency department | 000 | 2 | NIH | 1/20/2025 | $78,328 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R37CA283575 | Targeting Metabolic Crosstalk in Pancreatic Cancer | 001 | 2 | NIH | 5/22/2025 | $44,533 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R37CA283575 | Targeting Metabolic Crosstalk in Pancreatic Cancer | 000 | 2 | NIH | 4/10/2025 | $400,786 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | U19AI172725 | MDRO Carriage, Transmission, Sequelae, and Prevention in Nursing Homes | 001 | 3 | NIH | 5/9/2025 | $3,252,905 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | U01AI180164 | Impact of aging on human B cell vaccine responses | 000 | 2 | NIH | 4/17/2025 | $565,200 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | U01HG011745 | Pediatric Mendelian Genomics Research Center | 000 | 5 | NIH | 5/1/2025 | $2,074,563 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01HD113752 | STRESS, MEMORY, AND RUMINATION IN MALTREATED ADOLESCENTS | 000 | 2 | NIH | 4/16/2025 | $617,307 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35NS122140 | La Spada Outstanding Investigator Award | 000 | 5 | NIH | 5/9/2025 | $1,162,302 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | U01EY034594 | Correlating Genomic AMD Risk Variants with Lipid Composition and Phagocytic Function of Patient-Derived Induced Pluripotent Stem Cell (iPSC)-derived Retinal Pigment Epithelium (RPE) | 000 | 3 | NIH | 3/27/2025 | $393,500 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01NS130044 | Investigation of neural ensembles driving pain chronification | 000 | 3 | NIH | 11/8/2024 | $304,346 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM145254 | Regulation and impact of alternative splicing in biology and disease | 002 | 4 | NIH | 6/10/2025 | $392,500 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM149572 | Molecular Mechanisms of Telomere Length Homeostasis | 001 | 3 | NIH | 4/11/2025 | $392,500 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R33HD102988 | Mobile Diagnosis of Congenital Genetic Conditions: A Model for Screening and Surveillance in Low-Resource Settings | 000 | 3 | NIH | 1/8/2025 | $300,417 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01ES025767 | Toxicological importance of CYP3A4 catalysis and inhibition | 000 | 9 | NIH | 1/13/2025 | $561,595 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | U24MH133236 | UC Irvine Center for the production and distribution of cell-type-specific viral targeting reagents | 000 | 3 | NIH | 4/25/2025 | $945,779 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01MD015186 | Sleep and health disparities among Asian Americans: roles of stressors and protective factors | 001 | 5 | NIH | 4/21/2025 | $66,829 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01MD015186 | Sleep and health disparities among Asian Americans: roles of stressors and protective factors | 000 | 5 | NIH | 12/22/2024 | $601,457 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AG076835 | Investigating the interface of epigenetics and metabolism underlying memory formation in the adult, aging, and AD brain | 001 | 4 | NIH | 6/9/2025 | $57,682 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AG076835 | Investigating the interface of epigenetics and metabolism underlying memory formation in the adult, aging, and AD brain | 000 | 4 | NIH | 3/7/2025 | $648,932 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01EY031834 | Integration and functionality of retinal organoid transplants | 000 | 5 | NIH | 3/14/2025 | $554,601 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01EY034501 | Precision genome editing in vivo to treat retinal diseases | 000 | 3 | NIH | 3/14/2025 | $618,911 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01EY034519 | Chemical Biology of the Visual Pigments | 000 | 3 | NIH | 3/14/2025 | $449,125 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | T32GM154637 | Medical Scientist Training Program | 000 | 1 | NIH | 6/16/2025 | $584,450 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R37CA271172 | Effect of inflammation on JAK2 mutant evolution in the hematopoietic system: mathematical models and experiments | 001 | 4 | NIH | 4/25/2025 | $0 |
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