| | | | | | | | | | | | | | | | |
| | |
 | Issue Date FY: 2027 ( Subtotal = $0 ) |
| | 2027 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | UU755872 | Technology-Enabled Learning Collaborative Program | 01 | 1 | HRSA | 10/1/2026 | $0 |
|
| Issue Date FY: 2026 ( Subtotal = $227,650,441 ) (Continued on the next page) |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | K99GM164832 | Integrating physics-based and machine learning methods to accelerate computational drug design | 000 | 1 | NIH | 7/28/2026 | $126,489 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM161208 | Nitrogenase - From mechanistic investigation to heterologous expression | 000 | 1 | NIH | 3/13/2026 | $503,280 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM161209 | Nitrogenase - Where Haber-Bosch meets Fischer-Tropsch | 000 | 1 | NIH | 3/13/2026 | $487,953 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01DC023614 | SCOPE Screening Children's Oral Proficiency in English | 001 | 1 | NIH | 8/11/2026 | $645,741 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01DC023614 | SCOPE Screening Children's Oral Proficiency in English | 001 | 1 | NIH | 8/11/2026 | -$645,741 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01DC023614 | SCOPE Screening Children's Oral Proficiency in English | 000 | 1 | NIH | 7/30/2026 | $645,742 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R21AG081893 | Patch for hemodynamic and hemorrhage monitoring | 000 | 1 | NIH | 2/3/2026 | $408,504 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM157126 | Deciphering the Interactome and Functions of Disordered Microproteins | 000 | 2 | NIH | 8/26/2026 | $384,527 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01DA064341 | Neural mechanisms of motivational and cognitive impairment in opioid withdrawal | 000 | 2 | NIH | 5/27/2026 | $665,240 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01HL177188 | Development of integrated OCT/US/PAT system for intravascular Imaging | 000 | 2 | NIH | 6/18/2026 | $589,908 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R03DA062573 | Vitamin C protect against nicotine induced lung ailment | 000 | 2 | NIH | 6/18/2026 | $78,500 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01NS130616 | Neurotoxicity of particulate matter and its interaction with APOE in neurodegeneration | 000 | 3 | NIH | 8/14/2026 | $668,150 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | K08DK142008 | Investigation of Urethral Dysfunction in Female Urinary Incontinence | 000 | 2 | NIH | 3/25/2026 | $174,701 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F31HD121401 | Characterizing Xist in the white-footed deermouse (Peromyscus leucopus) | 001 | 1 | NIH | 5/22/2026 | $0 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F31HD121401 | Characterizing Xist in the white-footed deermouse (Peromyscus leucopus) | 000 | 1 | NIH | 5/22/2026 | $43,733 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F31CA301899 | Characterizing and targeting membrane properties tied to chemotherapeutic resistance in gliomas | 000 | 1 | NIH | 9/1/2026 | $47,383 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AG092608 | The impact of sex hormones on neural mechanisms of sleep-dependent memory during the reproductive age and menopause transition | 000 | 1 | NIH | 9/17/2026 | $778,918 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01GM163338 | Targeted Protein Degradation Utilizing Rpn-13 | 000 | 1 | NIH | 4/24/2026 | $448,510 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01EY038193 | Structurally Programmed Microfluidic Bioreactors to Manufacture Retinal Organoids for Regenerative Medicine | 000 | 1 | NIH | 9/17/2026 | $741,205 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R21AG101225 | Retrosplenial cortex hyperexcitability as an early driver of Alzheimer's Disease | 000 | 1 | NIH | 9/7/2026 | $431,750 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F31HL189241 | Validation and Prognostic Modeling of Physics-Informed Deep Learning for Cardiovascular Risk Stratification Beyond the Agatston Score | 000 | 1 | NIH | 9/17/2026 | $47,383 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R56NS147542 | Treg-mediated tolerance of dystrophin immunity | 000 | 1 | NIH | 9/17/2026 | $549,500 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01EY038840 | In Vivo Base Editing via Lipid Nanoparticles Targeting the Trabecular Meshwork for Glaucoma Therapy | 000 | 1 | NIH | 9/17/2026 | $590,849 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01EY039366 | Dynamics of CD4+ and CD8+ T Cells to Control Recurrent Ocular Herpes | 000 | 1 | NIH | 9/17/2026 | $627,998 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | UU755872 | Technology-Enabled Learning Collaborative Program | 00 | 1 | HRSA | 9/17/2026 | $475,000 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R61HD123427 | Toll-Like Receptor 4 Antagonism for Infertility Management in Polycystic Ovary Syndrome | 000 | 1 | NIH | 9/11/2026 | $435,691 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | K08AR088238 | Wearable Computational Sensing of Optical Biomarkers for Inflammatory Skin Diseases | 001 | 1 | NIH | 9/21/2026 | $10,800 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | K08AR088238 | Wearable Computational Sensing of Optical Biomarkers for Inflammatory Skin Diseases | 000 | 1 | NIH | 9/15/2026 | $139,010 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F31AR086648 | Genetic and Genomic Analysis of Developing Skeletal and Non-skeletal Tendon Attachments | 000 | 1 | NIH | 9/11/2026 | $48,179 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01NR022176 | Evaluation of a community co-developed intervention focused on quality of life in Spanish-speaking families impacted by childhood cancer | 000 | 1 | NIH | 9/18/2026 | $801,029 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | K99AG095287 | Investigating the Role of Sex, Sleep, and Menstrual Phase Interactions in Alzheimer's Disease Pathogenesis: A Remote Approach | 000 | 1 | NIH | 9/11/2026 | $127,029 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F31HD121372 | Regulation of the Gut-Reproductive Axis in Female Reproductive Health | 001 | 1 | NIH | 9/2/2026 | $0 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F31HD121372 | Regulation of the Gut-Reproductive Axis in Female Reproductive Health | 000 | 1 | NIH | 9/2/2026 | $48,179 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R56EY031834 | Integration and functionality of retinal organoid transplants | 000 | 6 | NIH | 9/19/2026 | $1,676,561 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | K00AG095134 | Elucidating the Influence of Ovarian Aging and Endocrine Shifts on Spatial Navigation, as an Early Diagnostic Target for Alzheimer's Disease | 000 | 2 | NIH | 9/4/2026 | $84,189 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R03AG101134 | Systemic Inflammatory Biomarkers for Alzheimer’s Disease Risk and Progression | 000 | 1 | NIH | 9/17/2026 | $157,000 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01GM165765 | Optical Probes for Polymerase Engineering | 000 | 1 | NIH | 9/4/2026 | $1,188,418 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | K99NS144617 | Post translational modifications as a therapeutic target for Huntington's Disease | 000 | 1 | NIH | 9/17/2026 | $119,840 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01CA287116 | Mechanisms of immunosuppression triggered by checkpoint blockade immunotherapy | 000 | 1 | NIH | 4/6/2026 | $648,626 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R21AI190786 | Vectorial Capacity of Invasive Anopheles stephensi in Ethiopia | 000 | 1 | NIH | 8/13/2026 | $196,250 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F31AI191957 | Improving the "kick" in HIV "kick and kill" cure approaches | 000 | 1 | NIH | 4/6/2026 | $47,383 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AI202117 | Regulatory mechanisms for production of infectious Chlamydia | 000 | 1 | NIH | 8/7/2026 | $760,663 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM163463 | Natural Product-Inspired Advances in Stereoselective Synthesis | 000 | 1 | NIH | 8/5/2026 | $526,832 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AG098878 | Abeta beta-Hairpin Peptides and Oligomers as Treatments for Alzheimer's Disease | 001 | 1 | NIH | 9/23/2026 | $0 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AG098878 | Abeta beta-Hairpin Peptides and Oligomers as Treatments for Alzheimer's Disease | 000 | 1 | NIH | 8/31/2026 | $739,365 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AG100345 | Multi-Omic Characterization of Molecular Pathways Driving Vulnerability and Resilience to Alzheimer's disease in the Oldest-Old | 000 | 1 | NIH | 9/1/2026 | $636,124 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01CA307676 | Mechanisms and Functional Roles of PARP1 Hyperactivation in Cancer | 000 | 1 | NIH | 6/26/2026 | $639,707 |
|
