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 | Issue Date FY: 2025 ( Subtotal = $338,276 ) (Continued on the next page) |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F31AG082485 | Neuropathological and spatial transcriptome brain maps in Octodon degus, a natural Alzheimer's disease rodent model | 000 | 2 | NIH | 11/14/2024 | $45,458 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01NS130044 | Investigation of neural ensembles driving pain chronification | 000 | 3 | NIH | 11/8/2024 | $304,346 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01CA260351 | Ethnicity-determined T cell responses and GARP/TGFbeta1 signaling in prostate cancer | 000 | 4 | NIH | 11/14/2024 | $323,224 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F30DA056215 | Investigation of neural ensembles underlying chronic pain | 000 | 3 | NIH | 10/31/2024 | $53,974 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AR079150 | Tissue Size and Precision Control in Growing Hair Follicles | 000 | 4 | NIH | 11/7/2024 | $493,010 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AG087280 | The role of immune deregulation and NGF dysmetabolism in the development of Alzheimer disease in individuals with Down syndrome | 000 | 1 | NIH | 10/22/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AG082127 | Single-cell transcriptomic and epigenomic analysis of brain cell vulnerabilities to tauopathies in early AD impacted brain regions | 000 | 2 | NIH | 10/25/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | OT2OD036428 | All of Us Southern California Consortium (AoUSCC): Engagement, Enrollment, and Retention of Diverse Populations | 000 | 1 | NIH | 11/1/2024 | $39,373 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | OT2OD036428 | All of Us Southern California Consortium (AoUSCC): Engagement, Enrollment, and Retention of Diverse Populations | 000 | 1 | NIH | 11/1/2024 | $10,774 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | H8H49598 | FY 2021 Ending the HIV Epidemic - Primary Care HIV Prevention | 02 | 2 | HRSA | 10/9/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM149294 | Mechanisms and regulation of mRNA 3' processing | 000 | 2 | NIH | 11/13/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AR079992 | Role of the FAAH-OUT locus in cutaneous wound healing | 002 | 3 | NIH | 11/13/2024 | $633,672 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM127071 | Innovative Tools for Chemical Synthesis: Metal-Hydride Catalysis, Medicinal Motifs, and Molecular Probes | 000 | 7 | NIH | 11/6/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F31AG077880 | Statistical methods for enriched clinical trials with applications to Alzheimer's disease research | 000 | 2 | NIH | 11/14/2024 | -$28,045 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM153291 | Understanding Mechanisms of Organic Reactions and Processes through Imaging | 000 | 1 | NIH | 11/6/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM139617 | Maternal transcription factors shaping early embryonic chromatin landscape | 000 | 4 | NIH | 11/15/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01EY033746 | Impact of routine eye care coverage on access to eye care and fall-related outcomes among low-income Medicare enrollees | 000 | 4 | NIH | 11/6/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM145307 | Intrinsic and extrinsic control of epithelial tissue stem cell activity | 000 | 3 | NIH | 11/6/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM148236 | Accelerating drug discovery via ML-guided iterative design and optimization | 000 | 2 | NIH | 11/13/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM153231 | Development of new methods and strategies for the synthesis of complex molecules | 000 | 1 | NIH | 11/14/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM140890 | Activity-Based DNA-Encoded Library Technology | 000 | 4 | NIH | 11/13/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM148350 | Ubiquitin and Metabolite Signaling | 000 | 2 | NIH | 11/13/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM127102 | UV to blue neuronal phototransduction mechanisms | 000 | 7 | NIH | 11/13/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM145249 | Advancing Proteomics Technologies to Decipher the Ubiquitin-Proteasome System | 000 | 3 | NIH | 11/13/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R21AR080407 | Mechanistic and Translational Investigations of HSPB8-associated dominant rimmed vacuolar myopathy | 000 | 1 | NIH | 11/7/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM136297 | Synthetic genetic systems for rapid biomolecular evolution in vivo | 000 | 5 | NIH | 11/5/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AG062706 | Diagnosis and Risk factors of hippocampal sclerosis of aging and limbic predominant age related TDP-43 encephalopathy; common Alzheimer’s mimics | 000 | 6 | NIH | 11/5/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM149572 | Molecular Mechanisms of Telomere Length Homeostasis | 000 | 2 | NIH | 11/5/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM153227 | Regulatory Mechanisms of PP2A Family Phosphatases | 000 | 1 | NIH | 11/5/2024 | $0 |
| | 2025 | 2023 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F31NS118865 | Regulation of Monocyte Entry to the Brain During Neuroinflammation | 000 | 3 | NIH | 10/23/2024 | -$226 |
| | 2025 | 2023 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F31AI161887 | Epidemiology of Plasmodium vivax in Ethiopia in varying Duffy Phenotypes | 000 | 2 | NIH | 10/23/2024 | -$875 |
| | 2025 | 2023 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | T32AI141346 | T32 for Training in Microbiology and Infectious Diseases | 000 | 5 | NIH | 10/24/2024 | $0 |
| | 2025 | 2023 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F31AG074703 | Neurobiological mechanisms of sleep and exercise effects on memory in older adults at risk for Alzheimer's disease | 000 | 3 | NIH | 10/23/2024 | -$13,640 |
| | 2025 | 2023 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R61AT012544 | Identification of botanical hHv1 channel blockers as analgesics for neuropathic pain | 000 | 1 | NIH | 10/15/2024 | $0 |
| | 2025 | 2023 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | H8G48037 | FY 2023 Expanding COVID-19 Vaccination | 02 | 1 | HRSA | 10/24/2024 | $0 |
| | 2025 | 2023 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM131920 | Metalloenzyme structure, function, and as targets for neurodegeneration and bacterial pathogenesis | 000 | 5 | NIH | 11/6/2024 | $0 |
| | 2025 | 2023 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | UL1TR001414 | Institute for Clinical and Translational Science | 000 | 9 | NIH | 11/14/2024 | -$1,507,246 |
| | 2025 | 2023 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM130367 | Multi-scaled Modeling of Electrostatic and Polarization Effects in Biomolecules | 000 | 5 | NIH | 11/4/2024 | $0 |
| | 2025 | 2023 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | K22CA234399 | Elucidating the regulation of RNA methylation by mTOR signaling in cancer | 000 | 2 | NIH | 10/29/2024 | -$7,766 |
| | 2025 | 2022 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | U01AR073159 | Multiscale Models of Wound Cell Plasticity for Regeneration | 001 | 5 | NIH | 10/29/2024 | -$1,138 |
| | 2025 | 2022 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | U01AR073159 | Multiscale Models of Wound Cell Plasticity for Regeneration | 000 | 5 | NIH | 10/29/2024 | -$6,609 |
| | 2025 | 2022 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | U24NS107210 | UCI-NEXT, a NeuroNEXT site | 000 | 5 | NIH | 10/28/2024 | -$1 |
| | 2025 | 2022 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R21AG073787 | ENGINEERED HUMAN MICROGLIA AS A CELL-BASED THERAPY FOR A-BETA PLAQUE REMOVAL | 000 | 2 | NIH | 10/15/2024 | -$6 |
| | 2025 | 2022 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | 90PH0010 | The PHIT Workforce Development Program | 11 | 1 | DHHS/OS | 10/31/2024 | $0 |
| | 2025 | 2022 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | 90PH0010 | The PHIT Workforce Development Program | 10 | 1 | DHHS/OS | 10/11/2024 | $0 |
| | 2025 | 2022 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01NS109810 | Piezo1 in neural stem cell mechano-regulation | 000 | 5 | NIH | 11/13/2024 | $0 |
| | 2025 | 2022 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R00MH118425 | Novel approaches to study AMPA receptor trafficking and LTP | 000 | 5 | NIH | 11/8/2024 | $0 |
| | 2025 | 2022 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01GM090056 | Characterization of the mammalian mRNA 3'-end processing complex | 000 | 13 | NIH | 11/14/2024 | $0 |
| | 2025 | 2022 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01EY030304 | Non-Invasive Femtosecond Laser Glaucoma Surgery Guided by Micron-Resolution OCT | 000 | 4 | NIH | 11/1/2024 | $0 |
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