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 | Issue Date FY: 2025 ( Subtotal = $191,275,891 ) (Continued on the next page) |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R56AA031271 | Modeling a national Graduated-BAC per se policy for 21-24 y/o drivers to reduce alcohol impaired driving injury and fatal crashes | 000 | 2 | NIH | 7/28/2025 | $139,444 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM153231 | Development of new methods and strategies for the synthesis of complex molecules | 002 | 2 | NIH | 8/13/2025 | $373,669 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM153231 | Development of new methods and strategies for the synthesis of complex molecules | 002 | 2 | NIH | 8/13/2025 | -$336,303 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM153231 | Development of new methods and strategies for the synthesis of complex molecules | 001 | 2 | NIH | 1/8/2025 | $336,303 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | U24AT012603 | Effective Network to advance Scientific Evidence related to Mechanisms of music-Based interventions (ENSEMBLE) | 003 | 3 | NIH | 8/11/2025 | $513,600 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | U01NS139215 | Southern California Undiagnosed Disease Network | 000 | 2 | NIH | 7/17/2025 | $742,099 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | U01NS139215 | Southern California Undiagnosed Disease Network | 000 | 2 | NIH | 7/17/2025 | $25,000 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AI185349 | The Role of Interferon Lambda in Alpha Herpesvirus Neuroinvasion | 000 | 1 | NIH | 1/27/2025 | $471,159 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F31DA059982 | Epigenetic Mechanisms Underlying Drug-seeking Behavior: Role of HDAC3 in Regulating Gene Expression within the MHb Cholinergic Population for Cocaine-induced Relapse-like Behavior | 002 | 2 | NIH | 7/21/2025 | $45,414 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R33AT012544 | Identification of botanical hHv1 channel blockers as analgesics for neuropathic pain | 002 | 3 | NIH | 8/1/2025 | $443,123 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01EY036478 | The role of monocytes and neutrophils in fungal keratitis | 001 | 2 | NIH | 8/8/2025 | $555,669 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | U01DA053826 | Dynamic epigenomic landscape of opioid abuse following early-life adversity | 000 | 4 | NIH | 6/23/2025 | $691,904 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01NS121227 | Mitochondrial Zn2+ accumulation and the induction of ischemic neurodegeneration | 001 | 4 | NIH | 7/15/2025 | $56,168 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01NS121227 | Mitochondrial Zn2+ accumulation and the induction of ischemic neurodegeneration | 000 | 4 | NIH | 12/23/2024 | $505,515 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01CA272680 | Effectiveness of Out-of-Pocket Cost COMmunication and Financial Navigation (CostCOM) in Cancer Patients | 001 | 3 | NIH | 6/2/2025 | $61,308 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01CA272680 | Effectiveness of Out-of-Pocket Cost COMmunication and Financial Navigation (CostCOM) in Cancer Patients | 000 | 3 | NIH | 12/6/2024 | $551,777 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F32HD114452 | Evaluating pain communication and understanding in interpreted medical encounters in a pediatric emergency department | 001 | 2 | NIH | 6/9/2025 | $1,224 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F32HD114452 | Evaluating pain communication and understanding in interpreted medical encounters in a pediatric emergency department | 000 | 2 | NIH | 1/20/2025 | $78,328 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R37CA266042 | Defining the Mechanism of Genome Rearrangements in Ph-Like ALL to Determine Predictive Markers in High-Risk Hispanic Populations | 003 | 4 | NIH | 5/22/2025 | $40,684 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R37CA266042 | Defining the Mechanism of Genome Rearrangements in Ph-Like ALL to Determine Predictive Markers in High-Risk Hispanic Populations | 002 | 4 | NIH | 4/10/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R37CA266042 | Defining the Mechanism of Genome Rearrangements in Ph-Like ALL to Determine Predictive Markers in High-Risk Hispanic Populations | 001 | 4 | NIH | 3/12/2025 | $366,163 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | U01AI180164 | Impact of aging on human B cell vaccine responses | 000 | 2 | NIH | 4/17/2025 | $565,200 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R21NS139257 | New Kv7 modulators to stop sensitized overexcitation of neurons | 000 | 1 | NIH | 8/4/2025 | $407,113 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01GM161051 | Molecular lanterns for multiplexed imaging of RNA dynamics | 000 | 1 | NIH | 8/12/2025 | $1,890,339 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | T32GM154637 | Medical Scientist Training Program | 000 | 1 | NIH | 6/16/2025 | $584,450 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | DP2AT013749 | Chemical glycobiology tools to decipher host-microbiota interactions | 000 | 1 | NIH | 8/11/2025 | $1,227,751 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R21TR005645 | Accelerating the translation of oligonucleotide therapeutics by enhancing delivery | 000 | 1 | NIH | 6/16/2025 | $419,398 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R21HL177481 | Photostimulation of In Vitro Cardiac Tissue Models via Programmable Peptide Coassembly of Cell-Interfacing Donor-Acceptor Aggregates | 000 | 1 | NIH | 7/30/2025 | $350,112 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01DK138911 | Differential Spatial cAMP Signaling in the Pancreatic Beta cell | 000 | 1 | NIH | 7/21/2025 | $705,817 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01EY034519 | Chemical Biology of the Visual Pigments | 000 | 3 | NIH | 3/14/2025 | $449,125 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01EY034501 | Precision genome editing in vivo to treat retinal diseases | 000 | 3 | NIH | 3/14/2025 | $618,911 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F30MH140515 | Investigating the neural mechanisms of positive and negative social interactions | 000 | 1 | NIH | 8/7/2025 | $46,540 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01DK121146 | Epigenetic Regulation of Mitochondrial Homeostasis and Energy Metabolism | 001 | 7 | NIH | 6/23/2025 | $493,084 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | RF1MH132680 | On circuit mechanisms of reward behaviors after early-life adversity | 000 | 3 | NIH | 8/6/2025 | $2,067,956 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | T35EY035966 | Summer Mentoring and Research Training in Eye and Vision Research (SMART EVR) | 000 | 1 | NIH | 7/11/2025 | $36,221 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R37CA271172 | Effect of inflammation on JAK2 mutant evolution in the hematopoietic system: mathematical models and experiments | 003 | 4 | NIH | 5/22/2025 | $53,979 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AG067073 | Using nicotine to reverse age-related auditory processing deficits | 001 | 5 | NIH | 6/10/2025 | $44,400 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F30CA306157 | Understanding Treg-mediated modulation of microglia in breast cancer brain metastasis | 000 | 1 | NIH | 7/16/2025 | $46,540 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AG067073 | Using nicotine to reverse age-related auditory processing deficits | 000 | 5 | NIH | 3/19/2025 | $499,478 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R34AI184342 | Oral N-Acetylglucosamine as Anti-Neuroinflammatory Add-on therapy for Multiple Sclerosis (NANA-MS) | 000 | 1 | NIH | 7/29/2025 | $263,892 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R37CA271172 | Effect of inflammation on JAK2 mutant evolution in the hematopoietic system: mathematical models and experiments | 001 | 4 | NIH | 4/25/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R37CA271172 | Effect of inflammation on JAK2 mutant evolution in the hematopoietic system: mathematical models and experiments | 000 | 4 | NIH | 3/20/2025 | $485,814 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R56AR085100 | Skin cell heterogeneity in sensitivity to mustard-induced cell death | 000 | 1 | NIH | 7/30/2025 | $1 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R56AR085100 | Skin cell heterogeneity in sensitivity to mustard-induced cell death | 000 | 1 | NIH | 7/30/2025 | $607,670 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01ES037475 | Environmental Determinants, Maternal Postpartum Depression, and Mental-Emotional-Behavioral Disorders in Urban-Dwelling Children | 000 | 1 | NIH | 7/25/2025 | $931,568 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01EY031834 | Integration and functionality of retinal organoid transplants | 000 | 5 | NIH | 3/14/2025 | $554,601 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | T32MH119049 | Howard Schneiderman Training Program in Learning and Memory | 002 | 7 | NIH | 7/25/2025 | $169,624 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01HL177188 | Development of integrated OCT/US/PAT system for intravascular Imaging | 000 | 1 | NIH | 8/13/2025 | $617,366 |
| | 2025 | 2025 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM157126 | Deciphering the Interactome and Functions of Disordered Microproteins | 000 | 1 | NIH | 8/13/2025 | $384,527 |
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