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 | Issue Date FY: 2026 ( Subtotal = $111,520,048 ) (Continued on the next page) |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | U01HG011745 | Pediatric Mendelian Genomics Research Center | 002 | 5 | NIH | 4/7/2026 | $1,863,473 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F31AG082485 | Neuropathological and spatial transcriptome brain maps in Octodon degus, a natural Alzheimer's disease rodent model | 001 | 3 | NIH | 3/25/2026 | $576 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F31AG082485 | Neuropathological and spatial transcriptome brain maps in Octodon degus, a natural Alzheimer's disease rodent model | 000 | 3 | NIH | 1/14/2026 | $46,770 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | U01AG076791 | Cell-type-specific neural circuit connectomes in the mouse models of aging and Alzheimer's disease | 000 | 5 | NIH | 5/5/2026 | $2,651,729 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM149572 | Molecular Mechanisms of Telomere Length Homeostasis | 000 | 4 | NIH | 4/2/2026 | $392,500 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R33HD102988 | Mobile Diagnosis of Congenital Genetic Conditions: A Model for Screening and Surveillance in Low-Resource Settings | 003 | 4 | NIH | 3/30/2026 | $7,887 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R33HD102988 | Mobile Diagnosis of Congenital Genetic Conditions: A Model for Screening and Surveillance in Low-Resource Settings | 002 | 4 | NIH | 3/30/2026 | $22,173 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R33HD102988 | Mobile Diagnosis of Congenital Genetic Conditions: A Model for Screening and Surveillance in Low-Resource Settings | 001 | 4 | NIH | 2/5/2026 | $70,982 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R33HD102988 | Mobile Diagnosis of Congenital Genetic Conditions: A Model for Screening and Surveillance in Low-Resource Settings | 000 | 4 | NIH | 1/28/2026 | $199,557 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F30EY033642 | microRNA-204 and microRNA-211 regulation of RPE phagocytosis | 000 | 5 | NIH | 1/12/2026 | $54,538 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | K23EY036491 | Spatial Frequency Domain Imaging to Investigate Mechanistic Constituents in Active Thyroid Eye Disease | 000 | 2 | NIH | 4/27/2026 | $257,920 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01GM163338 | Targeted Protein Degradation Utilizing Rpn-13 | 000 | 1 | NIH | 4/24/2026 | $448,510 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AI198692 | Therapeutic potential and mechanism of action of leelamine-derived isonitriles for malaria and babesiosis | 000 | 1 | NIH | 5/11/2026 | $823,548 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AG096669 | Longitudinal relationships between Alzheimer's disease pathophysiology, local sleep expression, and sleep-dependent memory across preclinical stages | 001 | 1 | NIH | 4/30/2026 | $0 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AG096669 | Longitudinal relationships between Alzheimer's disease pathophysiology, local sleep expression, and sleep-dependent memory across preclinical stages | 000 | 1 | NIH | 1/26/2026 | $619,099 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F31AI191957 | Improving the "kick" in HIV "kick and kill" cure approaches | 000 | 1 | NIH | 4/6/2026 | $47,383 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01CA287116 | Mechanisms of immunosuppression triggered by checkpoint blockade immunotherapy | 000 | 1 | NIH | 4/6/2026 | $648,626 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F31NS149735 | Developing innovative small-molecule lysosomal degraders for pathogenic protein aggregates in human disease | 000 | 1 | NIH | 5/11/2026 | $47,896 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F32EY037536 | Scalable Prime Editor Evolution for Correction of Inherited Retinal Diseases | 000 | 1 | NIH | 4/3/2026 | $79,480 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | F32EY037536 | Scalable Prime Editor Evolution for Correction of Inherited Retinal Diseases | 001 | 1 | NIH | 4/3/2026 | $0 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R21AI196970 | Molecular Architecture of the Vaccinia virus factory | 000 | 1 | NIH | 2/10/2026 | $235,500 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01CA309212 | Protoacoustic Imaging for 3D Mapping the Bragg Peak in Real Time during Proton Therapy | 000 | 1 | NIH | 4/6/2026 | $648,049 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01CA308352 | Type 1 Innate Lymphoid Cells: Mechanisms and Anti-AML Potential | 000 | 1 | NIH | 4/7/2026 | $586,364 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | K01DK143200 | Targeting BNC2 Neurons for Diabetes Treatment | 000 | 1 | NIH | 4/13/2026 | $132,423 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM161681 | Rapid, high throughput acquisition of 3D morphology of single cells | 000 | 1 | NIH | 4/3/2026 | $493,884 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R21AG081893 | Patch for hemodynamic and hemorrhage monitoring | 000 | 1 | NIH | 2/3/2026 | $408,504 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM161208 | Nitrogenase - From mechanistic investigation to heterologous expression | 000 | 1 | NIH | 3/13/2026 | $503,280 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R35GM161209 | Nitrogenase - Where Haber-Bosch meets Fischer-Tropsch | 000 | 1 | NIH | 3/13/2026 | $487,953 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R00AR083536 | Decoding the repair and immunomodulatory functions of lymphatic vessels in wound healing | 000 | 4 | NIH | 2/5/2026 | $249,000 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R21EY038406 | Exploring Novel Mechanisms of Obstructive Meibomian gland Dysfunction | 000 | 1 | NIH | 5/4/2026 | $431,750 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R21AG093390 | Correction of VCP Disease Pathology with Antisense Oligonucleotides | 000 | 1 | NIH | 5/4/2026 | $431,750 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R21TR006265 | Accelerated Antibody Evolution Under Functional Selection | 000 | 1 | NIH | 5/4/2026 | $413,771 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R21AI190954 | Characterization of a novel histidine phosphotransfer system involved in the virulence of Mycobacterium tuberculosis | 000 | 1 | NIH | 1/28/2026 | $141,712 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R21AI191078 | Vancomycin-Teixobactin Conjugates | 000 | 1 | NIH | 2/17/2026 | $404,866 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R21AI196939 | Functional Expansion of Regulatory T Cells to Limit CNS Autoimmunity | 000 | 1 | NIH | 1/29/2026 | $431,750 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AG078201 | Microglia dysregulation and SYK signaling in Alzheimer's disease | 000 | 2 | NIH | 3/3/2026 | $537,718 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01DA064341 | Neural mechanisms of motivational and cognitive impairment in opioid withdrawal | 000 | 2 | NIH | 5/27/2026 | $665,240 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | K08DK142008 | Investigation of Urethral Dysfunction in Female Urinary Incontinence | 000 | 2 | NIH | 3/25/2026 | $174,701 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AG076835 | Investigating the interface of epigenetics and metabolism underlying memory formation in the adult, aging, and AD brain | 000 | 5 | NIH | 4/1/2026 | $721,033 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01AI194582 | Increasing Breadth of Immune Response by Single-Dose Influenza Vaccines | 000 | 1 | NIH | 4/1/2026 | $721,365 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R37CA271172 | Effect of inflammation on JAK2 mutant evolution in the hematopoietic system: mathematical models and experiments | 001 | 5 | NIH | 4/30/2026 | $87,317 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R37CA271172 | Effect of inflammation on JAK2 mutant evolution in the hematopoietic system: mathematical models and experiments | 000 | 5 | NIH | 4/20/2026 | $539,793 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01ES037475 | Environmental Determinants, Maternal Postpartum Depression, and Mental-Emotional-Behavioral Disorders in Urban-Dwelling Children | 000 | 2 | NIH | 6/1/2026 | $780,662 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01EY034519 | Chemical Biology of the Visual Pigments | 000 | 4 | NIH | 4/7/2026 | $448,925 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | T32MH119049 | Howard Schneiderman Training Program in Learning and Memory | 000 | 8 | NIH | 5/28/2026 | $186,216 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | T32GM154637 | Medical Scientist Training Program | 001 | 2 | NIH | 5/22/2026 | $707,005 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | R01DK138911 | Differential Spatial cAMP Signaling in the Pancreatic Beta cell | 000 | 2 | NIH | 4/6/2026 | $705,817 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | P30CA062203 | Cancer Center Support Grant | 001 | 28 | NIH | 4/23/2026 | $7,000 |
| | 2026 | 2026 | UNIVERSITY OF CALIFORNIA IRVINE | 160 ALDRICH HALL | IRVINE | CA | 92697-0001 | ORANGE | USA | P30CA062203 | Cancer Center Support Grant | 001 | 28 | NIH | 4/23/2026 | $235,499 |
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