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Combating Antibiotic Resistance Into the Next Generation (CARING)

Award Number: T32AI007036
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 07/01/1976
PERIOD OF PERFORMANCE END DATE: 06/30/2026

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Combating Antibiotic Resistance Into the Next Generation (CARING) - This application requests a renewal of support for the UCSD “Research in Infectious Disease” T32 Training Grant, with an updated scientific focus and leadership. The program, now in its 40th year, supports the career development of physician scientists who wish to pursue research training in infectious diseases (ID) and host- pathogen interactions. The goal of the T32 is to recruit trainees who wish to pursue rigorous research training that will place them on the pathway to productive, independent research careers. Because of the complexity of contemporary biomedical research and the highly competitive funding environment (especially for early career research scientists). The high level of commitment to each trainee in terms of training duration and intensity, coupled with the multidisciplinary character of the training experience has attracted outstanding applicants and has enabled them to be extremely successful in progressing to the next stages of development of careers as physician scientists. Based on a recently completed strategic planning process, we have devised a new leadership structure, recruited new world class research faculty, kept successful educational and training elements, while incorporating innovative new offerings -- all galvanized to address one of the greatest challenges facing modern medicine and public health: the global antibiotic resistance crisis. Our renewal proposal for Postdoctoral ID Training at UCSD, which we retitle “CARING: Combating Antibiotic Resistance into the Next Generation” leverages the institutional investment and educational resources of a major campus- wide initiative – the Collaborative to Halt Antibiotic-Resistant Microbes (CHARM). We retain core elements of our training structure that have yielded excellent trainee outcomes, including recruitment and selection processes that enlisted trainee cohorts with significant diversity from URM groups, unique T32 Fellow educational curricula (e.g. the CREST program) and our Mentors-in-Development (MiD) program for junior faculty. The fundamental change to our program is the AMR focus of research training, organized in 6 themes: 1) Deciphering Microbial Virulence; (2) Host Defense & Vaccinology, (3) Novel Therapeutic Discovery, (4) Microbiome Science, (5) Systems Biology & Engineering, and (6) Clinical Microbiology & Therapeutics. We have selected a world-class faculty the top 29 leading investigators with proven mentorship skills to comprise our new Research Training faculty (12 continuing + 17 new). Instead of 6 MD fellow slots, we will recruit talented Adult and Pediatric ID fellows across 5 MD slots + 2 PhD postdoctoral scientist slots to encourage interdisciplinary synergies between clinical and basic scientists. Dr. Victor Nizet, an eminent UCSD ID Physician-Scientist (>450 papers) with a superlative track record in postdoctoral fellow mentorship (>20 former trainees now independent faculty running research programs) assumes the role of Program Director. The overarching goal of the training program remains to prepare the next generation of ID physician scientists for highly productive careers in biomedical research with local, national and international impacts.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $669,590 )
2025	2025	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	001	45	7/10/2025	NON-COMPETING CONTINUATION	$10,355
2025	2025	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	000	45	4/21/2025	NON-COMPETING CONTINUATION	$659,235
														Subtotal = $669,590

Issue Date FY: 2024 ( Subtotal = $605,609 )
2024	2024	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	000	44	6/4/2024	NON-COMPETING CONTINUATION	$605,609
														Subtotal = $605,609

Issue Date FY: 2023 ( Subtotal = $543,416 )
2023	2023	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	000	43	5/15/2023	NON-COMPETING CONTINUATION	$543,416
														Subtotal = $543,416

Issue Date FY: 2022 ( Subtotal = $571,496 )
2022	2022	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	002	42	8/1/2022	NON-COMPETING CONTINUATION	$571,496
2022	2021	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	001	41	2/11/2022	COMPETING CONTINUATION	$182,370
2022	2020	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	000	40	2/11/2022	NON-COMPETING CONTINUATION	-$182,370
														Subtotal = $571,496

Issue Date FY: 2021 ( Subtotal = $427,360 )
2021	2021	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	001	41	6/3/2021	COMPETING CONTINUATION	$0
2021	2021	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	000	41	4/29/2021	COMPETING CONTINUATION	$427,360
														Subtotal = $427,360

Issue Date FY: 2020 ( Subtotal = $393,010 )
2020	2020	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	001	40	4/24/2020	NON-COMPETING CONTINUATION	$393,010
2020	2019	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	000	39	4/16/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $393,010

Issue Date FY: 2019 ( Subtotal = $361,922 )
2019	2019	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	000	39	6/25/2019	NON-COMPETING CONTINUATION	$361,922
														Subtotal = $361,922

Issue Date FY: 2018 ( Subtotal = $371,774 )
2018	2018	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	000	38	6/19/2018	NON-COMPETING CONTINUATION	$371,774
														Subtotal = $371,774

Issue Date FY: 2017 ( Subtotal = $366,913 )
2017	2017	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	002	37	5/22/2017	NON-COMPETING CONTINUATION	$366,913
2017	2016	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	001	36	3/21/2017	COMPETING CONTINUATION	$3,571
2017	2014	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	000	35	3/21/2017	NON-COMPETING CONTINUATION	-$3,571
														Subtotal = $366,913

Issue Date FY: 2016 ( Subtotal = $367,751 )
2016	2016	UNIVERSITY OF CALIFORNIA-SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	001	36	6/30/2016	COMPETING CONTINUATION	$367,751
2016	2014	UNIVERSITY OF CALIFORNIA-SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	000	35	6/27/2016	NON-COMPETING CONTINUATION	$0
														Subtotal = $367,751

Issue Date FY: 2014 ( Subtotal = $295,083 )
2014	2014	UNIVERSITY OF CALIFORNIA-SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	000	35	6/4/2014	NON-COMPETING CONTINUATION	$295,083
														Subtotal = $295,083

Issue Date FY: 2013 ( Subtotal = $411,841 )
2013	2013	UNIVERSITY OF CALIFORNIA-SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	000	34	6/4/2013	NON-COMPETING CONTINUATION	$411,841
														Subtotal = $411,841

Issue Date FY: 2012 ( Subtotal = $407,868 )
2012	2012	UNIVERSITY OF CALIFORNIA-SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	000	33	7/1/2012	NON-COMPETING CONTINUATION	$407,868
														Subtotal = $407,868

Issue Date FY: 2011 ( Subtotal = $392,255 )
2011	2011	UNIVERSITY OF CALIFORNIA-SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	000	32	8/12/2011	NON-COMPETING CONTINUATION	$392,255
														Subtotal = $392,255

Issue Date FY: 2010 ( Subtotal = $392,348 )
2010	2010	UNIVERSITY OF CALIFORNIA-SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	001	31	8/23/2010	COMPETING CONTINUATION	$392,348
2010	2008	UNIVERSITY OF CALIFORNIA-SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	000	30	11/25/2009	NON-COMPETING CONTINUATION	$0
														Subtotal = $392,348

Issue Date FY: 2008 ( Subtotal = $308,515 )
2008	2008	UNIVERSITY OF CALIFORNIA-SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	000	30	4/18/2008	NON-COMPETING CONTINUATION	$308,515
														Subtotal = $308,515

Issue Date FY: 2007 ( Subtotal = $318,476 )
2007	2007	UNIVERSITY OF CALIFORNIA-SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	000	29	9/4/2007	NON-COMPETING CONTINUATION	$318,476
														Subtotal = $318,476

Issue Date FY: 2006 ( Subtotal = $307,991 )
2006	2006	UNIVERSITY OF CALIFORNIA-SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Allergy and Infectious Diseases Research	000	28	7/7/2006	NON-COMPETING CONTINUATION	$307,991
														Subtotal = $307,991

Issue Date FY: 2005 ( Subtotal = $317,968 )
2005	2005	UNIVERSITY OF CALIFORNIA-SAN DIEGO	Q027	LA JOLLA	CA	92093	SAN DIEGO	USA	Microbiology and Infectious Diseases Research	000	27	6/30/2005	NON-COMPETING CONTINUATION	$317,968
														Subtotal = $317,968

Issue Date FY: 2004 ( Subtotal = $307,500 )
2004	2004	UNIVERSITY OF CALIFORNIA-SAN DIEGO	Q027	LA JOLLA	CA	92093	SAN DIEGO	USA	Microbiology and Infectious Diseases Research	000	26	6/11/2004	COMPETING CONTINUATION	$307,500
														Subtotal = $307,500

Issue Date FY: 2003 ( Subtotal = $278,358 ) (Continued on the next page)
Grand Total All Awards = $9,533,152

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Combating Antibiotic Resistance Into the Next Generation (CARING)

Award Number: T32AI007036

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 07/01/1976

PERIOD OF PERFORMANCE END DATE: 06/30/2026

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