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Rehabilitation of Airway Protection in Parkinson's Disease: Comparing In-Person and Telehealth Service Delivery Models

Award Number: R01NS126319
ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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PROJECT SUMMARY/ABSTRACT Progressive disorders of airway protection, such as swallowing disorders (dysphagia) and cough disorders (dystussia), are highly prevalent in PD and have significant negative implications for health and quality of life. In fact, aspiration pneumonia, commonly associated with dysphagia/dystussia, is a leading cause of death in PD. Despite this, there is currently no established standard of care for the treatment of airway protective disorders in this population. Even more critically, approximately 40% of individuals with PD in the United States do not access rehabilitation services or receive specialized care for these potentially life-threatening airway protective deficits. Expiratory Muscle Strength Training (EMST) and Cough Skill Training (CST) have been found to improve airway protective disorders in PD and be feasible via telehealth. However, a significant clinical- research gap remains in that no one has demonstrated that clinical outcomes are comparable (non-inferior) when these treatments are delivered via telehealth versus in-person – a gap that we are currently working to fill with our ongoing parent R01(R01 NS126319-01). Furthermore, it is important to assess the impact of patient burden on treatment adherence and clinical outcomes in the short- and long-term in both modalities. This gap limits access to these important services with detrimental effects to health, quality of life, and healthcare disparities. An additional significant gap that impacts the advancement of this important work is a major lack in doctoral level scholars with strong training and mentorship in the area of clinical-translational work in airway protection (i.e., swallowing and cough) and its rehabilitation. This challenge is compounded by an especially low number of trainees from underrepresented backgrounds. Our long-term goal is to improve the health outcomes of individuals with PD and other neurodegenerative diseases, specifically as they relate to airway protective dysfunction. This long-term goal will be achieved through validating and improving access to efficacious interventions and through the effective training and mentorship of a diverse workforce of scholars with expertise in airway protection and its rehabilitation. The objective of this Landis Mentorship award supplement is to provide key support to enrich the training experiences of current and future trainees in airway protection. Our current parent R01 will serve as a living classroom from and through which research and enriching training opportunities will be developed.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $875,910 )
2024	2024	TEACHERS COLLEGE COLUMBIA UNIVERSITY	525 W 120TH ST	NEW YORK	NY	10027	NEW YORK	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	002	3	8/28/2024	SUPPLEMENT FOR EXPANSION	$0
2024	2024	TEACHERS COLLEGE COLUMBIA UNIVERSITY	525 W 120TH ST	NEW YORK	NY	10027	NEW YORK	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	003	3	8/29/2024	SUPPLEMENT FOR EXPANSION	$143,000
2024	2024	TEACHERS COLLEGE COLUMBIA UNIVERSITY	525 W 120TH ST	NEW YORK	NY	10027	NEW YORK	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	3	8/2/2024	SUPPLEMENT FOR EXPANSION	$149,196
2024	2024	TEACHERS COLLEGE COLUMBIA UNIVERSITY	525 W 120TH ST	NEW YORK	NY	10027	NEW YORK	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	3	7/18/2024	NON-COMPETING CONTINUATION	$583,714
														Subtotal = $875,910

Issue Date FY: 2023 ( Subtotal = $606,700 )
2023	2023	TEACHERS COLLEGE, COLUMBIA UNIVERSITY	525 W 120TH ST	NEW YORK	NY	10027	NEW YORK	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	2	7/14/2023	NON-COMPETING CONTINUATION	$606,700
														Subtotal = $606,700

Issue Date FY: 2022 ( Subtotal = $625,126 )
2022	2022	TEACHERS COLLEGE, COLUMBIA UNIVERSITY	525 W 120TH ST	NEW YORK	NY	10027	NEW YORK	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	1	8/26/2022	NEW	$625,126
														Subtotal = $625,126

Grand Total All Awards = $2,107,736

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Rehabilitation of Airway Protection in Parkinson's Disease: Comparing In-Person and Telehealth Service Delivery Models

Award Number: R01NS126319

ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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