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DROSOPHILA GENOMICS RESOURCE CENTER

Award Number: P40OD010949
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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DROSOPHILA GENOMICS RESOURCE CENTER - Project Summary: The Drosophila Genomics Resource Center (DGRC) supports the international community of scientists utilizing Drosophila melanogaster for biomedical research. The mission of the DGRC is to 1) provide broad access to genomics resources by acquiring, authenticating, archiving, curating, and distributing genomics resources including clones, vectors, and cell lines; 2) facilitate effective use of these genomics resources by providing guidance and support; and 3) improve the genomics resources and protocols available for Drosophila research. By preserving vital research materials and distributing them efficiently, the DGRC assures economical access to important research reagents, and enhances scientific rigor and reproducibility. The first aim of this proposal is to continue to strengthen the successful DGRC programs by: A) Continue to acquire, archive, curate, and distribute Drosophila resources including clones, vectors, and cell lines for supporting fundamental research of biological processes and modeling of aspects of human disease. B) Pilot a program with Indiana University Clinical and Translational Science Institute (CTSI) to promote Drosophila genomics reagents for use in non-Drosophila labs; C) Manage the cost recovery program and resource center to maximize the long-term viability of the DGRC and the benefits to its users and the NIH. The second aim is to improve and update our curation process, data management systems and web interface, and incorporate FAIR and TRUST guiding principles into our reagents, metadata and linking data to other repositories. The goal is to maximize the long-term viability of the DGRC and its benefits to users and the NIH. The third aim is to increase the utility of Drosophila as a model system by generating new resources and protocols through four projects: A) Increase the authentication, and reproducibility and quality control of DGRC reagents; B) Generate gut derived cell lines and pilot and expand to generate a neuroblast derived cell line; C) Continue to expand the catalog of recombination mediated cassette exchange compatible stable attP Drosophila cell lines; D) Collaborate to develop metabolic sensors and standards for aerobic glycolysis and other biosynthetic pathways.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $544,901 )
2025	2025	TRUSTEES OF INDIANA UNIVERSITY	107 S INDIANA AVE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	003	21	3/6/2025	NON-COMPETING CONTINUATION	$544,901
2025	2024	TRUSTEES OF INDIANA UNIVERSITY	107 S INDIANA AVE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	001	20	2/18/2025	COMPETING CONTINUATION	$261,852
2025	2023	TRUSTEES OF INDIANA UNIVERSITY	107 S INDIANA AVE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	002	19	2/18/2025	SUPPLEMENT FOR EXPANSION	-$235,000
2025	2022	TRUSTEES OF INDIANA UNIVERSITY	107 S INDIANA AVE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	000	19	2/18/2025	NON-COMPETING CONTINUATION	-$26,852
														Subtotal = $544,901

Issue Date FY: 2024 ( Subtotal = $681,125 )
2024	2024	TRUSTEES OF INDIANA UNIVERSITY	107 S INDIANA AVE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	000	20	3/7/2024	COMPETING CONTINUATION	$203,409
2024	2024	TRUSTEES OF INDIANA UNIVERSITY	107 S INDIANA AVE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	002	20	6/14/2024	COMPETING CONTINUATION	$242,716
2024	2024	TRUSTEES OF INDIANA UNIVERSITY	107 S INDIANA AVE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	001	20	4/24/2024	COMPETING CONTINUATION	$235,000
														Subtotal = $681,125

Issue Date FY: 2023 ( Subtotal = $235,000 )
2023	2023	TRUSTEES OF INDIANA UNIVERSITY	107 S INDIANA AVE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	001	19	5/27/2023	SUPPLEMENT FOR EXPANSION	$235,000
2023	2022	TRUSTEES OF INDIANA UNIVERSITY	107 S INDIANA AVE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	000	19	10/31/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $235,000

Issue Date FY: 2022 ( Subtotal = $544,552 )
2022	2022	TRUSTEES OF INDIANA UNIVERSITY	107 S INDIANA AVE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	000	19	3/29/2022	NON-COMPETING CONTINUATION	$490,096
2022	2022	TRUSTEES OF INDIANA UNIVERSITY	107 S INDIANA AVE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	001	19	5/23/2022	NON-COMPETING CONTINUATION	$54,456
														Subtotal = $544,552

Issue Date FY: 2021 ( Subtotal = $717,052 )
2021	2021	TRUSTEES OF INDIANA UNIVERSITY	107 S INDIANA AVE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	001	18	7/16/2021	SUPPLEMENT FOR EXPANSION	$172,500
2021	2021	TRUSTEES OF INDIANA UNIVERSITY	107 S INDIANA AVENUE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	000	18	4/6/2021	NON-COMPETING CONTINUATION	$544,552
														Subtotal = $717,052

Issue Date FY: 2020 ( Subtotal = $544,552 )
2020	2020	TRUSTEES OF INDIANA UNIVERSITY	107 S INDIANA AVENUE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	000	17	4/2/2020	NON-COMPETING CONTINUATION	$544,552
														Subtotal = $544,552

Issue Date FY: 2019 ( Subtotal = $708,981 )
2019	2019	TRUSTEES OF INDIANA UNIVERSITY	BRYAN HALL 107 S INDIANA AVENUE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	004	16	9/12/2019	SUPPLEMENT FOR EXPANSION	$141,489
2019	2019	TRUSTEES OF INDIANA UNIVERSITY	BRYAN HALL 107 S INDIANA AVENUE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	003	16	8/24/2019	SUPPLEMENT FOR EXPANSION	$22,940
2019	2019	TRUSTEES OF INDIANA UNIVERSITY	BRYAN HALL 107 S INDIANA AVENUE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	002	16	3/30/2019	NON-COMPETING CONTINUATION	$544,552
2019	2018	TRUSTEES OF INDIANA UNIVERSITY	BRYAN HALL 107 S INDIANA AVENUE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	001	15	2/8/2019	COMPETING CONTINUATION	-$127,988
2019	2017	TRUSTEES OF INDIANA UNIVERSITY	BRYAN HALL 107 S INDIANA AVENUE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	000	14	2/8/2019	NON-COMPETING CONTINUATION	$127,988
														Subtotal = $708,981

Issue Date FY: 2018 ( Subtotal = $544,552 )
2018	2018	TRUSTEES OF INDIANA UNIVERSITY	BRYAN HALL 107 S INDIANA AVENUE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	002	15	7/3/2018	COMPETING CONTINUATION	$44,678
2018	2018	TRUSTEES OF INDIANA UNIVERSITY	BRYAN HALL 107 S INDIANA AVENUE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	003	15	7/11/2018	COMPETING CONTINUATION	$0
2018	2018	TRUSTEES OF INDIANA UNIVERSITY	BRYAN HALL 107 S INDIANA AVENUE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	006	15	8/17/2018	COMPETING CONTINUATION	$9,775
2018	2018	TRUSTEES OF INDIANA UNIVERSITY	BRYAN HALL 107 S INDIANA AVENUE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	005	15	8/1/2018	COMPETING CONTINUATION	$387,840
2018	2018	TRUSTEES OF INDIANA UNIVERSITY	BRYAN HALL 107 S INDIANA AVENUE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	001	15	4/17/2018	COMPETING CONTINUATION	$490,099
2018	2017	TRUSTEES OF INDIANA UNIVERSITY	BRYAN HALL 107 S INDIANA AVENUE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	004	14	8/1/2018	NON-COMPETING CONTINUATION	-$387,840
2018	2017	TRUSTEES OF INDIANA UNIVERSITY	BRYAN HALL 107 S INDIANA AVENUE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	000	14	4/11/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $544,552

Issue Date FY: 2017 ( Subtotal = $524,292 )
2017	2017	TRUSTEES OF INDIANA UNIVERSITY	BRYAN HALL 107 S INDIANA AVENUE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	001	14	8/1/2017	NON-COMPETING CONTINUATION	$38,781
2017	2017	TRUSTEES OF INDIANA UNIVERSITY	205C BRYAN HALL, 105 N INDIANA AVE	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	000	14	3/15/2017	NON-COMPETING CONTINUATION	$485,511
														Subtotal = $524,292

Issue Date FY: 2016 ( Subtotal = $539,457 )
2016	2016	INDIANA UNIVERSITY, BLOOMINGTON	509 EAST 3RD STREET	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	000	13	3/10/2016	EXTENSION WITH OR WITHOUT FUNDS	$539,457
														Subtotal = $539,457

Issue Date FY: 2015 ( Subtotal = $528,668 )
2015	2015	INDIANA UNIVERSITY, BLOOMINGTON	509 EAST 3RD STREET	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	000	12	2/21/2015	NON-COMPETING CONTINUATION	$528,668
														Subtotal = $528,668

Issue Date FY: 2014 ( Subtotal = $534,063 )
2014	2014	INDIANA UNIVERSITY, BLOOMINGTON	509 EAST 3RD STREET	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	000	11	4/11/2014	NON-COMPETING CONTINUATION	$534,063
														Subtotal = $534,063

Issue Date FY: 2013 ( Subtotal = $539,456 )
2013	2013	INDIANA UNIVERSITY, BLOOMINGTON	509 EAST 3RD STREET	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	002	10	9/3/2013	COMPETING CONTINUATION	$289,762
2013	2013	INDIANA UNIVERSITY, BLOOMINGTON	509 EAST 3RD STREET	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	004	10	9/27/2013	COMPETING CONTINUATION	$0
2013	2013	INDIANA UNIVERSITY, BLOOMINGTON	509 EAST 3RD STREET	BLOOMINGTON	IN	47405	MONROE	USA	Research Infrastructure Programs	003	10	9/21/2013	COMPETING CONTINUATION	$249,694
2013	2012	INDIANA UNIVERSITY, BLOOMINGTON	509 EAST 3RD STREET	BLOOMINGTON	IN	47405	MONROE	USA	National Center for Research Resources	001	9	8/29/2013	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2013	2012	INDIANA UNIVERSITY, BLOOMINGTON	509 EAST 3RD STREET	BLOOMINGTON	IN	47405	MONROE	USA	National Center for Research Resources	000	9	7/1/2013	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
														Subtotal = $539,456

Issue Date FY: 2012 ( Subtotal = $756,364 ) (Continued on the next page)
Grand Total All Awards = $7,943,015

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DROSOPHILA GENOMICS RESOURCE CENTER

Award Number: P40OD010949

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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