Monday, February 16, 2026 2/16/2026

UNE Center for Cell Signaling Research

Award Number: P20GM152330
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 01/01/2024
PERIOD OF PERFORMANCE END DATE: 12/31/2028

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UNE Center for Cell Signaling Research - Cellular systems such as the nervous, immune, vascular systems and bone do not work in isolation, but are functionally integrated and communicate extensively both in health and disease states. Defects or dysfunction in cell signaling are fundamental drivers of human disease, and our ability to meet contemporary clinical challenges, including neurodegenerative and metabolic disease, chronic pain and optimizing healthy aging, requires a broader understanding of mechanisms of intercellular and intracellular communication. The proposed UNE Center for Cell Signaling Research (CCSR) will build a critical mass of talented investigators with a broad research emphasis on cellular metabolism, inflammation and aging. The initial Research Project Leaders (RPLs), selected through a competitive process, bring diverse and complementary expertise from across UNE colleges and departments. Their research projects address discrete clinical challenges by investigating fundamental cell biological mechanisms that may have broad ramifications for human disease. New faculty recruitment and support of a pilot project program will ensure a continued pipeline of RPLs and further grow the Center. Investigators will be provided with a structured mentorship program to support both their professional and research program development in their progression to independent funding and beyond. The proposed Center will also expand the research infrastructure at UNE to support the innovative research programs of investigators in cell signaling. The proposed In Vitro Analytical Core will support the research of the RPLs with outstanding instrumentation and innovative services that are not broadly available elsewhere in the region, including primary cell and cell line culturing, transfection and analysis through functional imaging as well as transcriptional and protein-based analysis. The core will be housed in newly renovated research space that will be contiguous with an existing UNE Histology and Imaging Core, providing a unique suite of resources to support research at UNE. Institutional commitments include additional protected research time for RPLs and institutional matching funds for the pilot project program. In addition, the university has committed to hiring 3 additional investigators whose research programs will complement those of the existing faculty. The Center will also benefit from strong continued institutional investment into research infrastructure, as well as well-established collaborations with neighboring IDeA state programs in Maine and New Hampshire. Research infrastructure will be enhanced by laboratory renovations, purchasing new instrumentation, and key support for personnel. Additional institutional support has been committed for each of these. With sound financial and administrative management and regular assessments of performance with specified bench marks, the CCSR will be well- positioned to make a significant impact in optimizing healthy, pain-free aging and in finding new treatments for neurodegenerative and metabolic diseases.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $1,917,000 )
2026	2026	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	000	3	12/30/2025	NON-COMPETING CONTINUATION	$1,917,000
														Subtotal = $1,917,000

Issue Date FY: 2025 ( Subtotal = $2,130,000 )
2025	2025	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	000	2	12/24/2024	NON-COMPETING CONTINUATION	$1,917,000
2025	2025	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	001	2	8/20/2025	NON-COMPETING CONTINUATION	$213,000
														Subtotal = $2,130,000

Issue Date FY: 2024 ( Subtotal = $2,367,000 )
2024	2024	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	000	1	12/29/2023	NEW	$2,367,000
														Subtotal = $2,367,000

Grand Total All Awards = $6,414,000

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UNE Center for Cell Signaling Research

Award Number: P20GM152330

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 01/01/2024

PERIOD OF PERFORMANCE END DATE: 12/31/2028

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