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Interdisciplinary Center of Excellence for the Study of Pain and Sensory Function

Award Number: P20GM103643
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/15/2012
PERIOD OF PERFORMANCE END DATE: 05/31/2024

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Interdisciplinary Center of Excellence for the Study of Pain and Sensory Function - Treatment of chronic pain continues to rely on old drugs such as gabapentinoids, reuptake blockers and opioids, all of which have severe side effects that diminish quality of life. Tolerance develops to opioids with chronic use, and an increase in opioid prescriptions has contributed to the growing opioid addiction epidemic. There is an urgent need for finding alternative treatments for treatment of both acute chronic pain. The goal of the COBRE Phase II is to continue the development of a Center for the Study of Pain and Sensory Function that will significantly contribute to the scientific understanding of the neurobiology of acute and chronic pain, facilitating the discovery of novel therapies. Significant progress was made during Phase I: four project leaders were successful in receiving NIH support and three COBRE pilot project grants seeded studies that subsequently received extramural support. Targets for recruitment were exceeded with the addition of both senior and junior faculty members to our Center. Two research cores were established and new lab space was created through renovations. The Center will continue to build on these accomplishments, leveraging COBRE support to garner additional institutional investment in the program. Our research cores will continue to collaborate with those at other regional IDeA program funded institutions, efficiently utilizing our resources as we work towards increased sustainability. Specific Aim 1 will create a critical mass of pain researchers necessary to sustain a vibrant research center and enhance their ability to compete for extramural research support. This Aim will be accomplished by fostering the pain related research programs of four current UNE faculty members who have not received R01 or comparable Research Project Grant support. In addition, funds will be provided for pilot projects to support early stage yet innovative pain-related studies. Finally, we will recruit an additional three investigators whose research programs will complement those of the existing faculty. Specific Aim 2 will expand neuroscience research infrastructure at UNE, providing access to core facilities that allow investigators to carry out cutting edge research on the neurobiological processes involved in the development of chronic pain. This aim will be accomplished through funding key support personnel and the purchase of equipment for the two research cores established during Phase I (the Behavior Core and the Histology and Imaging Core). Expanded research core services will include mouse genotyping and expert consultations for breeding strategies required for maintaining transgenic mouse colonies (Behavior Core), and a service to validate antibodies used by COBRE center researchers (Histology and Imaging Core). With continued investment provided through Phase II funding and institutional support, we will build on our early success and clearly establish the Center as a leader in pain research.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2021	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	000	10	11/27/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $0 )
2023	2021	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	000	10	8/30/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = $0 )
2022	2021	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	001	10	4/19/2022	NON-COMPETING CONTINUATION	$0
2022	2021	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	000	10	2/2/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2021 ( Subtotal = $2,142,323 )
2021	2021	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	000	10	6/2/2021	NON-COMPETING CONTINUATION	$2,142,323
														Subtotal = $2,142,323

Issue Date FY: 2020 ( Subtotal = $2,142,323 )
2020	2020	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	001	9	6/1/2020	NON-COMPETING CONTINUATION	$2,142,323
2020	2019	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	000	8	11/6/2019	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $2,142,323

Issue Date FY: 2019 ( Subtotal = $2,457,836 )
2019	2019	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	002	8	9/9/2019	SUPPLEMENT FOR EXPANSION	$315,513
2019	2019	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	001	8	5/29/2019	NON-COMPETING CONTINUATION	$2,142,323
2019	2018	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	000	7	1/7/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,457,836

Issue Date FY: 2018 ( Subtotal = $2,131,283 )
2018	2018	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	002	7	5/25/2018	NON-COMPETING CONTINUATION	$2,131,283
2018	2017	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	001	6	3/6/2018	COMPETING CONTINUATION	$2,908
2018	2016	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	000	5	3/6/2018	EXTENSION WITH OR WITHOUT FUNDS	-$2,908
														Subtotal = $2,131,283

Issue Date FY: 2017 ( Subtotal = $2,101,076 )
2017	2017	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	003	6	6/12/2017	COMPETING CONTINUATION	$2,101,076
2017	2016	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	001	5	12/30/2016	EXTENSION WITH OR WITHOUT FUNDS	$225,242
2017	2016	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	002	5	6/9/2017	EXTENSION WITH OR WITHOUT FUNDS	$0
2017	2015	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH RD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	000	4	12/30/2016	NON-COMPETING CONTINUATION	-$225,242
														Subtotal = $2,101,076

Issue Date FY: 2016 ( Subtotal = $1,848,194 )
2016	2016	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH ROAD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	000	5	5/19/2016	EXTENSION WITH OR WITHOUT FUNDS	$1,848,194
														Subtotal = $1,848,194

Issue Date FY: 2015 ( Subtotal = $1,880,487 )
2015	2015	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH ROAD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	000	4	6/11/2015	NON-COMPETING CONTINUATION	$1,880,487
														Subtotal = $1,880,487

Issue Date FY: 2014 ( Subtotal = $1,909,244 )
2014	2014	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH ROAD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	000	3	7/1/2014	NON-COMPETING CONTINUATION	$1,909,244
														Subtotal = $1,909,244

Issue Date FY: 2013 ( Subtotal = $1,875,586 )
2013	2013	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH ROAD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	000	2	6/25/2013	NON-COMPETING CONTINUATION	$1,875,586
														Subtotal = $1,875,586

Issue Date FY: 2012 ( Subtotal = $2,424,844 )
2012	2012	UNIVERSITY OF NEW ENGLAND	11 HILLS BEACH ROAD	BIDDEFORD	ME	04005	YORK	USA	Biomedical Research and Research Training	000	1	8/13/2012	NEW	$2,424,844
														Subtotal = $2,424,844

Grand Total All Awards = $20,913,196

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Interdisciplinary Center of Excellence for the Study of Pain and Sensory Function

Award Number: P20GM103643

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/15/2012

PERIOD OF PERFORMANCE END DATE: 05/31/2024

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