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Cardiothoracic Surgical Trials Network (CTSN) Linked Clinical Research Centers

Award Number: UM1HL088957
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/30/2007
PERIOD OF PERFORMANCE END DATE: 02/26/2026

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Cardiothoracic Surgical Trials Network (CTSN) Linked Clinical Research Centers - Project summary In this application for the renewal of the UM-01 NHLBI Cardiac Surgery Trial Network (CTSN) grant, PENN will continue to build upon our success in participating and developing cutting edge surgical trials in cardiac surgery and cardiovascular disease, develop a center of excellence for the training of a new generation of leaders in clinical research within in the field of cardiovascular surgery and mentor our designated partner and mentor the Catholic Health Initiative (CHI) St. Vincent Infirmary in Hot Springs, Arkansas, a large cardiac program in the Mississippi Delta. Specific AIM #1: In this renewal we will continue to develop, enroll and execute multi-centered, randomized cardiac surgical prospective trials as well as other novel and unique clinical research tools sponsored by the NHLBI CTSN. Specific AIM #2: We plan to collaborate closely with the Perelman School of Medicine, the Office of Clinical of Research and the Department of Translational Research and Science to develop a strong comprehensive mentoring and management plan for the affiliate site, CHI St. Vincent Infirmary. Our goal of the mentoring plan is to provide strong leadership, direction, collaboration, synergy and extensive skill development to support the development of a research experience and capacity at the St. Vincent Infirmary. SPECIFIC AIM #3: We will develop a Clinical Implementation Research Skills Program (CERP) at PENN. This program at the University of Pennsylvania will be designed to foster and train future cardiovascular specialists, surgeons, trialists and implementation scientists. We propose a two tier approach which will include the establishment of the PENN CERP Fellow Program which is aimed at mid and senior level trainees in surgery or junior faculty to achieve over two years to obtain a Masters of Health Science and Policy (MHSP degree at the University of Pennsylvania Perelman School of Medicine). The program will also include the PENN CERP scholar program which is designed for junior trainees such as medical students and junior residents. The scholars will receive a Clinical Research Certificate offered to the University of Pennsylvania through the Clinical Center of Epidemiology and Biostatistics (CCEB). The scholar program will be available to augment the overall mentoring program at the CHI St. Vincent Infirmary for interested students, MDs and nurses.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $541,158 )
2025	2025	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE	3451 WALNUT ST STE 440A	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	000	17	2/25/2025	NON-COMPETING CONTINUATION	$487,043
2025	2025	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE	3451 WALNUT ST STE 440A	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	001	17	8/5/2025	NON-COMPETING CONTINUATION	$54,115
														Subtotal = $541,158

Issue Date FY: 2024 ( Subtotal = $532,659 )
2024	2024	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE	3451 WALNUT ST STE 440A	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	001	16	6/20/2024	NON-COMPETING CONTINUATION	$43,482
2024	2024	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE	3451 WALNUT ST STE 440A	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	000	16	3/8/2024	NON-COMPETING CONTINUATION	$489,177
														Subtotal = $532,659

Issue Date FY: 2023 ( Subtotal = $545,832 )
2023	2023	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE	3451 WALNUT ST STE 440A	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	002	15	7/21/2023	NON-COMPETING CONTINUATION	$0
2023	2023	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE	3451 WALNUT ST STE 440A	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	003	15	8/31/2023	NON-COMPETING CONTINUATION	$0
2023	2023	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE	3451 WALNUT ST STE 440A	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	001	15	3/31/2023	NON-COMPETING CONTINUATION	$545,832
2023	2022	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE	3451 WALNUT ST STE 440A	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	000	14	1/5/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $545,832

Issue Date FY: 2022 ( Subtotal = $553,661 )
2022	2022	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE	3451 WALNUT ST STE 440A	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	000	14	3/3/2022	NON-COMPETING CONTINUATION	$498,292
2022	2022	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE	3451 WALNUT ST STE 440A	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	001	14	7/1/2022	NON-COMPETING CONTINUATION	$55,369
														Subtotal = $553,661

Issue Date FY: 2021 ( Subtotal = $561,263 )
2021	2021	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE	3451 WALNUT ST STE 440A	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	000	13	2/20/2021	NON-COMPETING CONTINUATION	$561,263
														Subtotal = $561,263

Issue Date FY: 2020 ( Subtotal = $568,211 )
2020	2020	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE	3451 WALNUT ST STE 440A	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	001	12	3/3/2020	NON-COMPETING CONTINUATION	$568,210
2020	2019	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE	3451 WALNUT ST STE 440A	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	000	11	12/19/2019	COMPETING CONTINUATION	$0
2020	2019	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE	3451 WALNUT ST STE 440A	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	002	11	9/16/2020	COMPETING CONTINUATION	$1
														Subtotal = $568,211

Issue Date FY: 2019 ( Subtotal = $597,664 )
2019	2019	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE	3451 WALNUT ST STE 440A	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	000	11	4/8/2019	COMPETING CONTINUATION	$597,665
2019	2017	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE	3451 WALNUT ST STE 440A	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	001	10	5/2/2019	NON-COMPETING CONTINUATION	-$1
														Subtotal = $597,664

Issue Date FY: 2017 ( Subtotal = $592,428 )
2017	2017	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA	3451 WALNUT ST	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	000	10	1/26/2017	NON-COMPETING CONTINUATION	$592,428
														Subtotal = $592,428

Issue Date FY: 2016 ( Subtotal = $207,572 )
2016	2016	UNIVERSITY OF PENNSYLVANIA	3451 WALNUT STREET	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	000	9	3/6/2016	EXTENSION WITH OR WITHOUT FUNDS	$207,572
														Subtotal = $207,572

Issue Date FY: 2015 ( Subtotal = $394,000 )
2015	2015	UNIVERSITY OF PENNSYLVANIA	3451 WALNUT STREET	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	000	8	1/20/2015	NON-COMPETING CONTINUATION	$394,000
														Subtotal = $394,000

Issue Date FY: 2014 ( Subtotal = $392,000 )
2014	2014	UNIVERSITY OF PENNSYLVANIA	3451 WALNUT STREET	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	000	7	2/4/2014	NON-COMPETING CONTINUATION	$360,000
2014	2014	UNIVERSITY OF PENNSYLVANIA	3451 WALNUT STREET	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	001	7	3/13/2014	NON-COMPETING CONTINUATION	$32,000
														Subtotal = $392,000

Issue Date FY: 2013 ( Subtotal = $380,802 )
2013	2013	UNIVERSITY OF PENNSYLVANIA	3451 WALNUT STREET	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Cardiovascular Diseases Research	000	6	7/15/2013	COMPETING CONTINUATION	$380,802
														Subtotal = $380,802

Grand Total All Awards = $5,867,250

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Cardiothoracic Surgical Trials Network (CTSN) Linked Clinical Research Centers

Award Number: UM1HL088957

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/30/2007

PERIOD OF PERFORMANCE END DATE: 02/26/2026

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