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 | Issue Date FY: 2025 ( Subtotal = $146,732,190 ) (Continued on the next page) |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01AG069474 | Improving the sensitivity and specificity of MRI-based biomarkers in Alzheimer's disease | 000 | 3 | NIH | 3/21/2025 | $627,039 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R00NS133611 | Inflammation and plaque formation downstream of disrupted autophagy in Alzheimer's disease | 001 | 3 | NIH | 3/21/2025 | -$246,246 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01GM149671 | Multiomic single cell and spatial interrogation of mechanisms in cellular adaptation to stress | 000 | 2 | NIH | 2/18/2025 | $398,763 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | F31HD118759 | Investigating the Role of GSK3A in Cohesin Dynamics and Gene Regulation | 000 | 1 | NIH | 3/21/2025 | $48,974 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01CA299870 | Towards characterization of Epigenetic targets in Prostate Cancer | 000 | 1 | NIH | 2/24/2025 | $371,719 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | UM1HL088957 | Cardiothoracic Surgical Trials Network (CTSN) Linked Clinical Research Centers | 000 | 17 | NIH | 2/25/2025 | $487,043 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01MH129439 | Posterior cingulate cortex and executive control of episodic memory | 000 | 4 | NIH | 3/21/2025 | $578,587 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R35GM139541 | Phosphorelay signaling and regulation in bacteria | 001 | 5 | NIH | 2/18/2025 | $356,640 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01NS101108 | Network Dysfunction and Neuromodulation following TBI | 002 | 8 | NIH | 2/25/2025 | $361,125 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01NR020975 | Enhance Trial-Enriched Holistic Care to Eradicate Maternal Morbidity | 000 | 3 | NIH | 2/18/2025 | $695,857 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R21CA301137 | Tumor-site activated T cell redirecting autoantibodies | 000 | 1 | NIH | 2/24/2025 | $216,682 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01NS118921 | Cellular and molecular analysis of startle modulation | 000 | 10 | NIH | 3/5/2025 | $468,260 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01AG066650 | Fast and robust deep learning tools for analysis of neuroimaging data of Alzheimer's disease | 000 | 5 | NIH | 3/6/2025 | $629,864 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01EY036292 | Development of Two Novel AMD Models for Evaluation of RPE Protection by the Novel Antioxidant D-DHA | 000 | 2 | NIH | 3/27/2025 | $443,342 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01AG087091 | Aligning incentives across Medicaid and Medicare for nursing home residents with AD/ADRD | 000 | 2 | NIH | 3/6/2025 | $731,453 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | P30CA016520 | Abramson Cancer Center Support Grant | 000 | 49 | NIH | 3/5/2025 | $8,468,782 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | P01CA257904 | Translational Studies in FLASH Particle Radiotherapy | 000 | 4 | NIH | 3/5/2025 | $2,177,692 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01NS107969 | Mechanism of Sleep Regulation by SIK3 | 003 | 7 | NIH | 3/26/2025 | $350,161 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | K99DE033428 | Probing the role of Selenomonas sputigena in supragingival biofilm spatial structuring and virulence | 000 | 2 | NIH | 2/28/2025 | $127,062 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | F31DK139757 | The role of LDTg to VTA calcitonin receptor signaling in the control of food reward | 000 | 2 | NIH | 2/14/2025 | $36,784 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01HD110567 | Integrative risk modeling for early prediction of endometriosis and its long-term health outcomes | 000 | 3 | NIH | 3/25/2025 | $589,170 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01CA278837 | What fuels CAR T-cell serial killing | 000 | 3 | NIH | 2/14/2025 | $278,557 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01AI168312 | Regulation of germinal center responses by SARS-CoV-2 messenger RNA vaccines | 000 | 4 | NIH | 2/28/2025 | $624,919 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | F31HD118792 | Breaking Down the Balbiani Body and Germplasm: An Endogenous Structure and Function Analysis on the Buc Protein | 000 | 1 | NIH | 3/25/2025 | $48,974 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01AG076434 | Pathogenesis of Tauopathies | 000 | 3 | NIH | 3/7/2025 | $678,901 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01AR080895 | Treatment and Mechanisms of Diabetic Fracture Healing | 000 | 3 | NIH | 2/14/2025 | $455,968 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01GM073791 | Structural-Functional Basis of Actin Cytoskeleton Dynamics | 000 | 20 | NIH | 3/24/2025 | $370,526 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01MH124897 | Validation of a Causal Model of Implementation | 000 | 5 | NIH | 3/25/2025 | $477,928 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R21HL172127 | Objective measures of sleepiness and cognitive function in different symptom subtypes of OSA | 000 | 2 | NIH | 2/28/2025 | $121,956 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01NS122570 | Protection against early SIV brain injury with adjunctive therapy to cART | 000 | 4 | NIH | 2/14/2025 | $790,121 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01GM101149 | DNA double-strand break chromatin alterations and genome integrity | 000 | 12 | NIH | 3/25/2025 | $295,495 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01AG074989 | Informing optimal first-line antihypertensive therapy: A rigorous comparative effectiveness analysis of ARBs vs. ACEIs on long-term risk of dementia, cancer, heart disease, and quality of life | 000 | 4 | NIH | 2/14/2025 | $681,131 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | P01AI131251 | SHIV Env-antibody coevolution as a molecular guide to HIV-1 V3 glycan targeted vaccine design | 000 | 9 | NIH | 2/28/2025 | $3,930,527 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | U01DK123594 | Human Pancreas Analysis Program for Type 2 Diabetes (HPAP-T2D) | 000 | 6 | NIH | 2/28/2025 | $2,999,756 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | F30MH136699 | Investigating the Role of GABAergic Interneurons in the Dorsomedial Striatum in Goal-Directed Behavior | 000 | 2 | NIH | 3/7/2025 | $36,806 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | D43TW011809 | Educating and Developing Bioethicists in Tanzania (ENGAGE) | 000 | 5 | NIH | 3/8/2025 | $247,560 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | K01HG013339 | Adults with childhood-onset genetic disease: planning for the future amid therapeutic innovation | 000 | 1 | NIH | 3/7/2025 | $174,302 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01DK136564 | Role of Alpha Cells in Pathogenesis of Type 1 Diabetes | 000 | 2 | NIH | 2/14/2025 | $489,783 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01AG085344 | Spatially resolved multi-omics profiling of human hippocampus in Aging and Alzheimer's Disease | 000 | 2 | NIH | 3/25/2025 | $554,146 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01CA291880 | Silver Telluride Nanoparticle Dual-Energy Mammography Contrast Agents For Breast Cancer Screening | 000 | 1 | NIH | 3/24/2025 | $554,188 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | F31DK135277 | Investigating folliculin as a regulator of VLDL-TG secretion in non-alcoholic fatty liver disease and steatohepatitis | 000 | 3 | NIH | 2/14/2025 | $39,796 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01AR083938 | Mechanisms underlying the formation and function of the sweat gland dermal niche | 000 | 2 | NIH | 3/7/2025 | $507,330 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01NS116504 | Optimized Intracranial EEG Targeting in Focal Epilepsy based upon Neuroimaging Connectomics | 000 | 5 | NIH | 3/10/2025 | $558,449 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01CA284748 | AYA ACCESS Study: An enhanced eHealth and Chat-bot enabled delivery model for clinical genetic services in community AYA cancer patients | 000 | 2 | NIH | 3/11/2025 | $618,971 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01EY031286 | Spatial and nonspatial knowledge | 000 | 5 | NIH | 2/14/2025 | $549,272 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | F30CA281080 | Mechanisms of Lymphatic Metastasis in Pancreatic Ductal Adenocarcinoma | 000 | 1 | NIH | 3/10/2025 | $36,662 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R35GM153180 | Transcription Factors Overcoming Chromatin Barriers to Control Cell Fate | 001 | 2 | NIH | 2/21/2025 | $608,540 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R01DK135958 | Comprehensive quantification of fuel use in cold-induced thermogenesis in vivo | 000 | 3 | NIH | 3/3/2025 | $515,068 |
| | 2025 | 2025 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 3451 WALNUT ST STE 440A | PHILADELPHIA | PA | 19104-6205 | PHILADELPHIA | USA | R33CA287135 | High Throughput Digital Droplet Assays for Ultrasensitive Multimodal (DNA, RNA, and Protein) Diagnostics | 000 | 2 | NIH | 3/3/2025 | $345,529 |
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