Monday, October 6, 2025 10/6/2025

AIDS and Cancer Specimen Resource (ACSR)

Award Number: UM1CA181255
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/23/2013
PERIOD OF PERFORMANCE END DATE: 08/31/2026

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AIDS and Cancer Specimen Resource (ACSR) - Abstract The AIDS epidemic, initially recognized in the early 1980's, currently affects more than 35 million people worldwide. Infection with the human immunodeficiency virus (HIV) is associated with a wide range of long term health complications including the development of cancer, currently a major cause of death among persons living with HIV/AIDS. The early form of the AIDS and Cancer Specimen Resource (ACSR) was established in 1994 as a cooperative agreement with the NCI with a mission to provide high quality biospecimens to researchers, a mission still paramount for the current ACSR. Principle investigators (MPIs) from the two legacy sites (GWU and UCSF) oversee the function of the ACSR to ensure the adherence to NCI best practices in this multinational program. The ACSR is currently the custodian for specimen collections from more than 20,000 individuals and makes these biospecimens available to eligible researchers studying HIV and cancer through an established specimen application process. In the past five years, investigators from more than 50 institutions have received research material from the ACSR. In addition, the ACSR has provided the centralized biospecimen collection and distribution functions for the AIDS Malignancy Consortium (AMC), which represents the NCI-funded international network of more than 30 clinical institutions involved in testing novel cancer therapies in HIV-infected individuals. The ACSR is structured into regional biospecimen repositories (RBRs) located in distinct geographical regions that reflect the US and global HIV epidemic and are unified (virtually) by an informatics infrastructure managed by the Hub for Integrated Informatics and Research Support (HIIRS). The RBRs are distinct but complementary in their diverse functions, with collaborative interactions fostered through the Governing Committee and ACSR-wide Working Groups that accomplish activities related to Science and Technology, Marketing and Outreach, Informatics, and Quality Management. As the HIV epidemic has evolved the types of cancers and the technologies used to study them have also changed. The newly reconfigured ACSR will have two divisions, both focused on obtaining the most important well-annotated (demographic, clinical, pathological and outcomes data) biospecimens for research as defined by investigator inquiries and the ACSR's scientific advisory board. The two MPIs, respectively will head the national and international AMC support program and the scientific direction of the ACSR. Both MPIs will work within the structure of the ACSR to obtain and provide to researcher's specimens most important for research in the current epidemic. Specific Aims include: 1) Acquire, store, and equitably distribute tumor tissues and biological fluids from individuals with HIV-associated malignancies (AIDS-defining cancers and non-AIDS defining cancers) to meet the biospecimen needs of researchers in HIV-associated malignancies; and 2) Promote the success of AMC clinical trials through mutually beneficial collaborations.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $4,831,022 )
2025	2025	GEORGE WASHINGTON UNIVERSITY (THE)	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Cancer Treatment Research	003	10	9/19/2025	SUPPLEMENT FOR EXPANSION	$411,640
2025	2025	GEORGE WASHINGTON UNIVERSITY (THE)	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Cancer Treatment Research	002	10	9/19/2025	SUPPLEMENT FOR EXPANSION	$456,101
2025	2025	GEORGE WASHINGTON UNIVERSITY (THE)	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Cancer Treatment Research	001	10	9/17/2025	SUPPLEMENT FOR EXPANSION	$3,963,281
2025	2023	GEORGE WASHINGTON UNIVERSITY (THE)	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Cancer Treatment Research	000	10	9/17/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $4,831,022

Issue Date FY: 2024 ( Subtotal = $4,723,702 )
2024	2024	GEORGE WASHINGTON UNIVERSITY (THE)	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Cancer Treatment Research	001	10	9/16/2024	SUPPLEMENT FOR EXPANSION	$4,723,702
2024	2023	GEORGE WASHINGTON UNIVERSITY (THE)	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Cancer Treatment Research	000	10	3/28/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $4,723,702

Issue Date FY: 2023 ( Subtotal = $4,831,082 )
2023	2023	GEORGE WASHINGTON UNIVERSITY (THE)	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Cancer Treatment Research	002	10	8/30/2023	NON-COMPETING CONTINUATION	$4,831,082
2023	2022	GEORGE WASHINGTON UNIVERSITY (THE)	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Cancer Treatment Research	001	9	5/26/2023	NON-COMPETING CONTINUATION	$0
2023	2022	GEORGE WASHINGTON UNIVERSITY, THE	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Cancer Treatment Research	000	9	1/19/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $4,831,082

Issue Date FY: 2022 ( Subtotal = $4,844,653 )
2022	2022	GEORGE WASHINGTON UNIVERSITY, THE	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Cancer Treatment Research	001	9	8/17/2022	NON-COMPETING CONTINUATION	$4,830,717
2022	2021	GEORGE WASHINGTON UNIVERSITY, THE	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Cancer Treatment Research	000	8	5/5/2022	NON-COMPETING CONTINUATION	$0
2022	2018	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cancer Cause and Prevention Research	002	5	9/26/2022	SUPPLEMENT FOR EXPANSION	$13,936
														Subtotal = $4,844,653

Issue Date FY: 2021 ( Subtotal = $4,797,076 )
2021	2021	GEORGE WASHINGTON UNIVERSITY, THE	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Cancer Treatment Research	002	8	8/30/2021	NON-COMPETING CONTINUATION	$4,797,076
2021	2020	GEORGE WASHINGTON UNIVERSITY, THE	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Cancer Treatment Research	000	7	11/10/2020	NON-COMPETING CONTINUATION	$0
2021	2020	GEORGE WASHINGTON UNIVERSITY, THE	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Cancer Treatment Research	001	7	3/23/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $4,797,076

Issue Date FY: 2020 ( Subtotal = $4,317,263 )
2020	2020	GEORGE WASHINGTON UNIVERSITY, THE	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Cancer Treatment Research	005	7	9/14/2020	NON-COMPETING CONTINUATION	$613,949
2020	2020	GEORGE WASHINGTON UNIVERSITY, THE	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Cancer Treatment Research	004	7	8/27/2020	NON-COMPETING CONTINUATION	$3,703,314
2020	2019	GEORGE WASHINGTON UNIVERSITY, THE	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Cancer Treatment Research	001	6	4/1/2020	COMPETING CONTINUATION	$319,227
2020	2019	GEORGE WASHINGTON UNIVERSITY, THE	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Cancer Treatment Research	003	6	7/29/2020	COMPETING CONTINUATION	$57,922
2020	2018	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cancer Cause and Prevention Research	000	5	4/1/2020	SUPPLEMENT FOR EXPANSION	-$319,227
2020	2018	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cancer Cause and Prevention Research	002	5	7/29/2020	SUPPLEMENT FOR EXPANSION	-$57,922
														Subtotal = $4,317,263

Issue Date FY: 2019 ( Subtotal = $4,244,545 )
2019	2019	GEORGE WASHINGTON UNIVERSITY, THE	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Cancer Treatment Research	001	6	9/4/2019	COMPETING CONTINUATION	$144,545
2019	2019	GEORGE WASHINGTON UNIVERSITY, THE	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Cancer Treatment Research	000	6	8/30/2019	COMPETING CONTINUATION	$4,100,000
														Subtotal = $4,244,545

Issue Date FY: 2018 ( Subtotal = $3,000,000 )
2018	2018	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cancer Cause and Prevention Research	000	5	9/10/2018	SUPPLEMENT FOR EXPANSION	$3,000,000
														Subtotal = $3,000,000

Issue Date FY: 2017 ( Subtotal = $4,111,196 )
2017	2017	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 420	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Cancer Cause and Prevention Research	002	5	8/28/2017	NON-COMPETING CONTINUATION	$4,111,196
2017	2016	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 420	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Cancer Cause and Prevention Research	001	4	1/21/2017	EXTENSION WITH OR WITHOUT FUNDS	$1,036,872
2017	2015	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 420	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Cancer Cause and Prevention Research	000	3	1/21/2017	NON-COMPETING CONTINUATION	-$1,036,872
														Subtotal = $4,111,196

Issue Date FY: 2016 ( Subtotal = $4,131,087 )
2016	2016	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cancer Cause and Prevention Research	000	4	9/5/2016	EXTENSION WITH OR WITHOUT FUNDS	$4,131,087
														Subtotal = $4,131,087

Issue Date FY: 2015 ( Subtotal = $4,234,901 )
2015	2015	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cancer Cause and Prevention Research	000	3	9/10/2015	NON-COMPETING CONTINUATION	$4,234,901
														Subtotal = $4,234,901

Issue Date FY: 2014 ( Subtotal = $3,717,183 )
2014	2014	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cancer Cause and Prevention Research	000	2	9/3/2014	NON-COMPETING CONTINUATION	$3,717,183
														Subtotal = $3,717,183

Issue Date FY: 2013 ( Subtotal = $3,987,956 )
2013	2013	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Cancer Cause and Prevention Research	000	1	9/23/2013	NEW	$3,987,956
														Subtotal = $3,987,956

Grand Total All Awards = $55,771,666

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AIDS and Cancer Specimen Resource (ACSR)

Award Number: UM1CA181255

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/23/2013

PERIOD OF PERFORMANCE END DATE: 08/31/2026

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