Wednesday, February 5, 2025 2/5/2025

A-Z Clinical Trials Unit

Award Number: UM1AI069452
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Group Awards By:

View Award Abstract

The Alabama to Zambia Clinical Trials Unit (A-to-Z CTU) represents a collaboration between the University of Alabama at Birmingham (UAB) and the Centre for Infectious Diseases Research in Zambia (CIDRZ). UAB has been continuously funded to perform NIH-funded HIV network clinical trials since 1990 and in 2015 added the CIDRZ CRS at the request of DAIDS. Over the past 6 years, our team has successfully enrolled over 1000 participants, including 45% female and 59% minority participants, into 48 network trials and contributed to over 175 publications of the networks. We have met or exceeded the expectations regarding enrollment, retention, data management, pharmacy management, and laboratory facilities and metrics. The past performance of the A-to-Z CTU exemplifies the preparedness of our team to contribute to the science of the NIH-funded HIV clinical trials networks for the next seven years. In this application, we highlight the A-to-Z CTU commitment to HIV research with the following specific aims: Aim 1. Enroll and retain participants efficiently into HIV clinical trials at our two clinical research sites capable of yielding the highest quality data to meet the needs of the HVTN, the HPTN and the ACTG scientific networks and their respective scientific research agendas. Aim 2. Maintain a cohesive, integrated group of investigators and staff where communication, community engagement, interaction, problem solving, flexible staffing, quality data and sample management, and regulatory assurance currently exist as evident via our track record of high-quality performance. Aim 3. Contribute to the respective scientific agendas by remaining engaged with the network leadership to respond quickly to emerging scientific priorities, including the ability to rapidly scale-up a protocol- specific site for targeted, high-priority studies for any DAIDS-funded research network. Aim 4. Mentor a talented group of young investigators who will lay the foundation for continued excellence in this ever-changing field of HIV research domestically and internationally. We will leverage our long-standing experience in clinical trials to contribute to HIV research through the NIH- funded HIV clinical trial networks.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $867,254 )
2025	2025	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	000	19	11/22/2024	NON-COMPETING CONTINUATION	$867,254
														Subtotal = $867,254

Issue Date FY: 2024 ( Subtotal = $1,659,641 )
2024	2024	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	000	18	11/1/2023	NON-COMPETING CONTINUATION	$829,821
2024	2024	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	002	18	6/20/2024	NON-COMPETING CONTINUATION	$829,820
2024	2024	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	001	18	12/8/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,659,641

Issue Date FY: 2023 ( Subtotal = $1,686,852 )
2023	2023	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	002	17	6/7/2023	NON-COMPETING CONTINUATION	$1,007,677
2023	2023	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	000	17	11/22/2022	NON-COMPETING CONTINUATION	$855,005
2023	2020	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	001	14	2/9/2023	SUPPLEMENT FOR EXPANSION	-$175,830
														Subtotal = $1,686,852

Issue Date FY: 2022 ( Subtotal = $1,987,715 )
2022	2022	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	006	16	6/15/2022	NON-COMPETING CONTINUATION	$740,922
2022	2022	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	000	16	11/17/2021	NON-COMPETING CONTINUATION	$1,158,878
2022	2022	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	005	16	4/21/2022	NON-COMPETING CONTINUATION	$0
2022	2021	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	002	15	11/30/2021	COMPETING CONTINUATION	-$163,471
2022	2021	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	004	15	3/21/2022	COMPETING CONTINUATION	$152,673
2022	2020	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	007	14	9/26/2022	SUPPLEMENT FOR EXPANSION	$87,915
2022	2020	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	003	14	3/21/2022	NON-COMPETING CONTINUATION	-$152,673
2022	2020	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	001	14	11/30/2021	NON-COMPETING CONTINUATION	$163,471
														Subtotal = $1,987,715

Issue Date FY: 2021 ( Subtotal = $1,833,108 )
2021	2021	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	000	15	11/19/2020	COMPETING CONTINUATION	$864,251
2021	2021	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	004	15	4/14/2021	COMPETING CONTINUATION	$163,471
2021	2021	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	002	15	3/2/2021	COMPETING CONTINUATION	$968,857
2021	2020	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	003	14	4/14/2021	NON-COMPETING CONTINUATION	-$163,471
2021	2020	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	001	14	1/29/2021	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $1,833,108

Issue Date FY: 2020 ( Subtotal = $2,425,363 )
2020	2020	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	000	14	11/20/2019	NON-COMPETING CONTINUATION	$1,198,352
2020	2020	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	002	14	6/4/2020	NON-COMPETING CONTINUATION	$0
2020	2020	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	003	14	6/12/2020	SUPPLEMENT FOR EXPANSION	$300,000
2020	2020	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	001	14	6/1/2020	NON-COMPETING CONTINUATION	$927,011
														Subtotal = $2,425,363

Issue Date FY: 2019 ( Subtotal = $3,243,756 )
2019	2019	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	000	13	11/16/2018	NON-COMPETING CONTINUATION	$1,621,879
2019	2019	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	001	13	5/14/2019	NON-COMPETING CONTINUATION	$1,621,877
														Subtotal = $3,243,756

Issue Date FY: 2018 ( Subtotal = $1,624,063 )
2018	2018	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	001	12	2/14/2018	NON-COMPETING CONTINUATION	$270,678
2018	2018	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	000	12	11/24/2017	NON-COMPETING CONTINUATION	$541,354
2018	2018	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	002	12	5/17/2018	NON-COMPETING CONTINUATION	$812,031
														Subtotal = $1,624,063

Issue Date FY: 2017 ( Subtotal = $1,573,468 )
2017	2017	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	000	11	11/9/2016	NON-COMPETING CONTINUATION	$1,573,468
														Subtotal = $1,573,468

Issue Date FY: 2016 ( Subtotal = $1,650,759 )
2016	2016	UNIVERSITY OF ALABAMA AT BIRMINGHAM	1530 3rd Avenue South, AB 1170	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	000	10	11/24/2015	NON-COMPETING CONTINUATION	$1,650,759
														Subtotal = $1,650,759

Issue Date FY: 2015 ( Subtotal = $1,507,599 )
2015	2015	UNIVERSITY OF ALABAMA AT BIRMINGHAM	1530 3rd Avenue South, AB 1170	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	000	9	11/28/2014	NON-COMPETING CONTINUATION	$1,139,759
2015	2015	UNIVERSITY OF ALABAMA AT BIRMINGHAM	1530 3rd Avenue South, AB 1170	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	002	9	9/10/2015	NON-COMPETING CONTINUATION	$24,859
2015	2015	UNIVERSITY OF ALABAMA AT BIRMINGHAM	1530 3rd Avenue South, AB 1170	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	001	9	8/3/2015	NON-COMPETING CONTINUATION	$342,981
														Subtotal = $1,507,599

Issue Date FY: 2014 ( Subtotal = $1,863,909 ) (Continued on the next page)
2014	2014	UNIVERSITY OF ALABAMA AT BIRMINGHAM	1530 3rd Avenue South, AB 1170	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	002	8	3/3/2014	COMPETING CONTINUATION	$186,391
2014	2014	UNIVERSITY OF ALABAMA AT BIRMINGHAM	1530 3rd Avenue South, AB 1170	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	000	8	12/10/2013	COMPETING CONTINUATION	$837,186
2014	2014	UNIVERSITY OF ALABAMA AT BIRMINGHAM	1530 3rd Avenue South, AB 1170	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	004	8	7/3/2014	COMPETING CONTINUATION	-$589,937
2014	2014	UNIVERSITY OF ALABAMA AT BIRMINGHAM	1530 3rd Avenue South, AB 1170	BIRMINGHAM	AL	35294	JEFFERSON	USA	Allergy and Infectious Diseases Research	001	8	12/27/2013	COMPETING CONTINUATION	$840,332
Grand Total All Awards = $26,032,916

Page 1 of 2 (56 items)12

Top

All Categories

About

Search

Reports

Data Submission

Award Information

A-Z Clinical Trials Unit

Award Number: UM1AI069452

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer