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 | Issue Date FY: 2025 ( Subtotal = $109,600,460 ) (Continued on the next page) |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | F32DA058453 | Contributions of KCNQ2/3 channels to medium spiny neuron excitability and cocaine reward | 000 | 3 | NIH | 5/2/2025 | $77,037 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01AA029072 | Circadian and mitochondrial dysfunction in alcohol-related liver disease | 000 | 3 | NIH | 5/12/2025 | $457,851 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | K23MD018383 | Reducing health disparities in foregut cancers by using modifiable barriers to predict risk for inequitable care: a novel implementation sciencebased approach | 000 | 4 | NIH | 4/25/2025 | $161,797 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01CA270750 | Employing Humanized Microbiome Mice to Understand Immune Activation and Translational Therapeutic Potential in Glioblastoma | 000 | 3 | NIH | 5/7/2025 | $296,386 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01HD111059 | Examining the effects of live telehealth exercise training on cardiometabolic outcomes in wheelchair users | 000 | 3 | NIH | 1/23/2025 | $571,103 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01HL163666 | Dysregulation of cardiac signaling in disease and stress | 000 | 4 | NIH | 4/26/2025 | $351,460 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01HL156275 | Let-7b in BPD | 000 | 3 | NIH | 4/21/2025 | $498,938 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01HL158800 | Nuclear FAK-mediated VSMC differentiation via epigenetic reprograming invascular diseases | 000 | 5 | NIH | 3/31/2025 | $427,876 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01AI172796 | Molecular mechanisms underlying organ penetration in disseminated pneumococcal infection | 000 | 3 | NIH | 10/29/2024 | $622,109 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01AG081433 | Role of GlcSph in cognitive deficits in Lewy body dementias | 000 | 3 | NIH | 3/24/2025 | $539,442 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01EY032753 | ACE2 on gut barrier dysfunction and BRB disruption | 000 | 4 | NIH | 12/4/2024 | $369,431 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | F30AG085889 | Interactions between progranulin insufficiency and TDP-43 | 000 | 2 | NIH | 5/1/2025 | $42,629 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | U24AT011969 | Force-Based Manipulations Research Network | 000 | 4 | NIH | 4/9/2025 | $297,000 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | U24AT011969 | Force-Based Manipulations Research Network | 000 | 4 | NIH | 4/9/2025 | $172,937 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R21CA277267 | Targeting actionable liabilities in Merlin-deficient breast cancer | 000 | 2 | NIH | 11/18/2024 | $187,444 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | P01HL158500 | Early Life Stress Induced Mechanisms of Cardiovascular Disease Risk and Resilience | 000 | 3 | NIH | 1/22/2025 | $2,012,602 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01HL160982 | Natriuretic Peptide-Renin-Angiotensin-Aldosterone System Rhythm Axis and Nocturnal Blood Pressure | 000 | 4 | NIH | 12/18/2024 | $667,950 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01NS119479 | SULT4a1, a novel neuroprotective protein in stroke | 000 | 5 | NIH | 11/25/2024 | $346,308 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01AG075059 | The essentiality of serine and glycine for skeletal muscle regeneration in aging | 000 | 4 | NIH | 12/9/2024 | $294,048 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R21AI175868 | Divergence of V-region sequences from the human proteome as a factor in autoimmune diseases and the immunogenicity of therapeutic antibodies. | 000 | 2 | NIH | 11/5/2024 | $216,068 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | K23DK134756 | An Optimization trial of a stakeholder-enhanced intervention to improve the decisional partnership of Chronic Kidney Disease dyads using the multiphase optimization strategy: Project ImPart. | 000 | 3 | NIH | 4/24/2025 | $167,630 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01CA282701 | Role of CXCR3-CXCL10 signaling in T-ALL CNS disease | 000 | 2 | NIH | 3/28/2025 | $404,297 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01CA265981 | A novel, transferable sialylation-mediated mechanism of chemoradioresistance in GI cancer | 000 | 4 | NIH | 12/20/2024 | $330,111 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01CA259480 | MEF2D-Mediated Transcriptional Control of Acute Myeloid Leukemia | 000 | 4 | NIH | 12/3/2024 | $310,541 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01AG078708 | IMPORTANCE OF PERIODONTITIS IN THE INNATE IMMUNE REGULATION OF ALZHEIMER'S DISEASE | 000 | 3 | NIH | 3/7/2025 | $334,125 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | K23DK135844 | Social and Dietary Determinants of Kidney Stone Risk | 000 | 3 | NIH | 2/28/2025 | $182,101 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01DE032376 | Seniors Oral Health in Southeast Alaska | 001 | 3 | NIH | 3/27/2025 | $531,839 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01GM141546 | Role Of Retinoid Oxidoreductase Complex In Controlling The Embryonic Development | 000 | 3 | NIH | 3/25/2025 | $280,665 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01AG069251 | Motherhood Biographies and Midlife Women's Health | 001 | 5 | NIH | 12/23/2024 | $72,590 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01AG069251 | Motherhood Biographies and Midlife Women's Health | 000 | 5 | NIH | 12/20/2024 | $200,578 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01ES034846 | The role of lysosomal impairment in trichloroethylene induced Parkinsonian neurodegeneration | 000 | 2 | NIH | 12/13/2024 | $448,243 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01DK134402 | Regulation of Macrophage Phenotype by Ferritin Heavy Chain in CKD | 000 | 3 | NIH | 12/18/2024 | $356,995 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01ES034846 | The role of lysosomal impairment in trichloroethylene induced Parkinsonian neurodegeneration | 001 | 2 | NIH | 12/16/2024 | $122,700 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01CA269365 | ELAVL1 role in glioblastoma heterogeneity through intercellular gene transfer mediated by cell fusion and tunneling membrane nanotube formation | 000 | 3 | NIH | 2/13/2025 | $305,724 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R00AG075179 | Role of Rab10 in Alzheimer's disease | 000 | 4 | NIH | 11/25/2024 | $224,099 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01EY033620 | Brain-gut-retina axis in diabetic retinopathy | 000 | 3 | NIH | 1/16/2025 | $524,816 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01HL171136 | Novel strategies to mitigate cardiac damage and dysfunction following invasive pneumococcal disease | 000 | 2 | NIH | 4/24/2025 | $580,596 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01HL168659 | Genetic and molecular basis of hematopoietic abnormalities in ZTTK syndrome | 000 | 3 | NIH | 12/27/2024 | $467,259 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | UM1AI069452 | A-Z Clinical Trials Unit | 001 | 19 | NIH | 4/25/2025 | $186,871 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | UM1AI069452 | A-Z Clinical Trials Unit | 001 | 19 | NIH | 4/25/2025 | $680,382 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | UM1AI069452 | A-Z Clinical Trials Unit | 000 | 19 | NIH | 11/22/2024 | $186,872 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | UM1AI069452 | A-Z Clinical Trials Unit | 000 | 19 | NIH | 11/22/2024 | $680,382 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01DK137784 | Comprehensive Analysis of Oxalate Homeostasis in Calcium Oxalate Kidney Stone Formers | 000 | 2 | NIH | 11/15/2024 | $589,796 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01CA248794 | Leukemia stem cell regulation and resistance | 000 | 5 | NIH | 1/8/2025 | $382,718 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R21CA288243 | CRISPR and Humanized mice-based Discovery of a Novel Drug target for HCC Therapy | 000 | 2 | NIH | 3/14/2025 | $156,204 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R21AI175964 | Describing the stable, non-covalent BclA-BxpB attachment in B. anthracis spores | 000 | 2 | NIH | 2/20/2025 | $180,056 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | K01MD017270 | Harnessing social determinant of health data to identify and engage high risk, socially vulnerable populations for diabetes prevention | 002 | 4 | NIH | 4/18/2025 | $129,524 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R01AG082089 | The role of IncRNA Neat1 in Alzheimer's disease and related memory deficits | 000 | 3 | NIH | 3/7/2025 | $591,400 |
| | 2025 | 2025 | UNIVERSITY OF ALABAMA AT BIRMINGHAM | 701 S 20TH STREET | BIRMINGHAM | AL | 35294-0001 | JEFFERSON | USA | R37AI169864 | Coordination of Innate and Adaptive Immunity in Intestinal Barrier Defense | 000 | 4 | NIH | 2/12/2025 | $567,962 |
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