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UCLA AIDS Prevention and Treatment Clinical Trials Unit

Award Number: UM1AI069424
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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UCLA AIDS Prevention and Treatment Clinical Trials Unit - Project Summary The overarching goal of the UCLA AIDS Prevention and Treatment Clinical Trials Unit (CTU) is to make significant contributions to the development and conduct of HIV treatment and prevention clinical studies in the context of the DAIDS-sponsored HIV Clinical Research Networks. The UCLA AIDS Prevention and Treatment Clinical Trials Unit (UCLA APT CTU) is a multidisciplinary research group composed of a core administrative unit and three clinical research sites (CRSs) in metropolitan Los Angeles, California, one CRS in Southern Brazil and a new CRS proposed in Buenos Aires, Argentina. We have over 25 years of leadership experience in the design, implementation, and conduct of clinical trials evaluating both therapeutic and prevention strategies in diverse populations across all age groups. Under the leadership of the multiple PIs, Judith Currier MD, MSc and Raphael J. Landovitz, MD, MSc, an experienced multidisciplinary investigator team including Eric Daar, MD, Steve Shoptaw, PhD, Breno Santos, MD, and Pedro Cahn, MD, PhD together with a group of early midcareer investigators, Kara Chew, MD, MSc, Jesse Clark, MD, MSc, and Omar Sued, MD, PhD, we will participate in the design and conduct of studies addressing the highest priority areas for Adult Therapeutics for HIV/AIDS, HIV Prevention, and HIV Vaccines. The CTU has an administrative core and CRS at the UCLA CARE Center and additional CRSs at Harbor-UCLA Medical Center, UCLA Vine Street Clinic, and at Grupo Hospitalar Conceição in Porto Alegre Brazil and at Fundación Huésped (FH), in Buenos Aires, Argentina. We have integrated our activities across adult medicine and between treatment and prevention to allow for an efficient and collaborative approach to addressing the highest priority research questions in HIV/AIDS. The CTU provides a gateway for the contributions of a cadre of outstanding established and emerging investigators at UCLA and from South America to contribute to clinical trials in HIV/AIDS. We place special emphasis on the recruitment of women and minorities in all aspects of our work. Shared resources for laboratory specimen processing and storage, regulatory management, community outreach, recruitment, and education, community advisory board (CAB) interactions across the Los Angeles-based sites promotes significant CTU-wide efficiency. Relevance The clinical research trials conducted by the UCLA AIDS Prevention Clinical Trials unit will have a direct beneficial effect on the health of millions of people worldwide who are living with or at risk for HIV, tuberculosis and hepatitis B, transforming the health of people with these infections and preventing new infections. The research conducted by the CTU will lead to significantly reducing morbidity and mortality, particularly among populations disproportionately affected by HIV/AIDS.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $3,585,709 )
2025	2025	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Allergy and Infectious Diseases Research	001	19	4/17/2025	NON-COMPETING CONTINUATION	$1,769,037
2025	2025	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Allergy and Infectious Diseases Research	000	19	11/25/2024	NON-COMPETING CONTINUATION	$1,816,672
														Subtotal = $3,585,709

Issue Date FY: 2024 ( Subtotal = $3,954,316 )
2024	2024	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Allergy and Infectious Diseases Research	000	18	11/7/2023	NON-COMPETING CONTINUATION	$2,402,159
2024	2024	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Allergy and Infectious Diseases Research	001	18	6/3/2024	NON-COMPETING CONTINUATION	$1,552,157
														Subtotal = $3,954,316

Issue Date FY: 2023 ( Subtotal = $3,794,297 )
2023	2023	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Allergy and Infectious Diseases Research	002	17	6/8/2023	NON-COMPETING CONTINUATION	$1,597,660
2023	2023	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Allergy and Infectious Diseases Research	001	17	11/22/2022	NON-COMPETING CONTINUATION	$2,196,637
2023	2022	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Allergy and Infectious Diseases Research	000	16	11/16/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $3,794,297

Issue Date FY: 2022 ( Subtotal = $4,384,228 )
2022	2022	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Allergy and Infectious Diseases Research	001	16	11/23/2021	NON-COMPETING CONTINUATION	$3,044,988
2022	2022	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Allergy and Infectious Diseases Research	003	16	6/15/2022	NON-COMPETING CONTINUATION	$1,339,240
2022	2022	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Allergy and Infectious Diseases Research	002	16	3/18/2022	NON-COMPETING CONTINUATION	$0
2022	2020	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Allergy and Infectious Diseases Research	000	14	11/22/2021	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $4,384,228

Issue Date FY: 2021 ( Subtotal = $5,828,205 )
2021	2021	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	000	15	11/19/2020	COMPETING CONTINUATION	$2,533,996
2021	2021	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	001	15	3/11/2021	COMPETING CONTINUATION	$3,294,218
2021	2021	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Allergy and Infectious Diseases Research	004	15	8/10/2021	COMPETING CONTINUATION	$120,267
2021	2020	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Allergy and Infectious Diseases Research	003	14	8/10/2021	NON-COMPETING CONTINUATION	-$120,267
2021	2020	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Allergy and Infectious Diseases Research	002	14	8/10/2021	SUPPLEMENT FOR EXPANSION	-$9
														Subtotal = $5,828,205

Issue Date FY: 2020 ( Subtotal = $4,362,345 )
2020	2020	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	002	14	6/5/2020	NON-COMPETING CONTINUATION	$2,031,171
2020	2020	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	000	14	11/19/2019	NON-COMPETING CONTINUATION	$2,031,173
2020	2020	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	001	14	6/3/2020	SUPPLEMENT FOR EXPANSION	$300,001
														Subtotal = $4,362,345

Issue Date FY: 2019 ( Subtotal = $4,522,429 )
2019	2019	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	002	13	9/12/2019	NON-COMPETING CONTINUATION	$0
2019	2019	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	000	13	11/20/2018	NON-COMPETING CONTINUATION	$2,261,215
2019	2019	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	001	13	5/22/2019	NON-COMPETING CONTINUATION	$2,261,214
														Subtotal = $4,522,429

Issue Date FY: 2018 ( Subtotal = $1,904,461 )
2018	2018	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	002	12	5/17/2018	NON-COMPETING CONTINUATION	$952,230
2018	2018	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	001	12	2/26/2018	NON-COMPETING CONTINUATION	$317,411
2018	2018	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	000	12	11/24/2017	NON-COMPETING CONTINUATION	$634,820
														Subtotal = $1,904,461

Issue Date FY: 2017 ( Subtotal = $1,641,447 )
2017	2017	UNIVERSITY OF CALIFORNIA, LOS ANGELES	11000 KINROSS AVE STE 102	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	000	11	11/14/2016	NON-COMPETING CONTINUATION	$1,641,447
														Subtotal = $1,641,447

Issue Date FY: 2016 ( Subtotal = $1,795,330 )
2016	2016	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	001	10	7/25/2016	NON-COMPETING CONTINUATION	$153,883
2016	2016	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	000	10	11/13/2015	NON-COMPETING CONTINUATION	$1,641,447
														Subtotal = $1,795,330

Issue Date FY: 2015 ( Subtotal = $1,604,376 )
2015	2015	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	000	9	11/14/2014	NON-COMPETING CONTINUATION	$1,604,376
														Subtotal = $1,604,376

Issue Date FY: 2014 ( Subtotal = $2,737,442 )
2014	2014	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	001	8	12/26/2013	COMPETING CONTINUATION	$637,780
2014	2014	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	002	8	3/6/2014	COMPETING CONTINUATION	$222,871
2014	2014	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	000	8	12/10/2013	COMPETING CONTINUATION	$1,381,072
2014	2014	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	004	8	8/12/2014	COMPETING CONTINUATION	$56,000
2014	2014	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	003	8	3/13/2014	COMPETING CONTINUATION	$439,719
														Subtotal = $2,737,442

Issue Date FY: 2013 ( Subtotal = $2,494,558 )
2013	2013	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	001	7	6/20/2013	NON-COMPETING CONTINUATION	$249,457
2013	2013	UNIVERSITY OF CALIFORNIA-LOS ANGELES, BOARD OF REGENTS	11000 KINROSS AVENUE	LOS ANGELES	CA	90095	LOS ANGELES	USA	Allergy and Infectious Diseases Research	000	7	11/28/2012	NON-COMPETING CONTINUATION	$2,245,101
														Subtotal = $2,494,558

Issue Date FY: 2012 ( Subtotal = $4,216,430 ) (Continued on the next page)
Grand Total All Awards = $46,825,573

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UCLA AIDS Prevention and Treatment Clinical Trials Unit

Award Number: UM1AI069424

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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