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Scripps Translational Science Institute

Award Number: UL1TR002550
ORGANIZATION: NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SOCIAL SERVICES
PERIOD OF PERFORMANCE START DATE: 05/01/2018
PERIOD OF PERFORMANCE END DATE: 06/30/2023

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Scripps Translational Science Institute - Overall Abstract The Scripps Translational Science Institute (STSI) is the center of the Scripps Hub, formed in 2007, dedicated to accelerating individualized medicine, improving medical research and clinical care, and training the future leaders of the biomedical workforce. The Scripps hub has included The Scripps Research Institute (TSRI) and Scripps Health (SH) as its principal components, along with the San Diego Supercomputer Center for its bioinformatic initiatives. In the new CTSA cycle, our partners have expanded to now include the California Institute for Medical Research (Calibr), recently made a Scripps Research Institute, and the Rady Children's Institute of Genomic Medicine (RCIGM). These 2 new partners will markedly increase our efforts for drug repurposing/ discovery and across the lifespan to the pediatric population. Digital medicine has been one of STSI's core strengths, with innovations to digitize clinical trials from end-to-end (enrollment to dissemination). Our focus on human genomics has been critical to building infrastructure at the hub, supporting many studies throughout the San Diego region including healthy aging (Wellderly), unknown diseases, molecular autopsy and rapid pathogen detection through sequencing. We received support from the CTSA Trial Innovation Network (TIN) for 2 of these projects. Recent STSI-supported projects feature a fusion of both genomics and digital medicine for mobile app development and clinical trials. An important affirmation of STSI's progress and contributions was its selection in 2016 by the NIH to be The Participant Center for the Precision Medicine Initiative (PMI) All of Us cohort. Many other aspects of the Scripps hub are undergoing remarkable growth. Our life science industry partners, which has been an essential STSI strategy, has expanded with more than 20 new collaborations over the past CTSA cycle. A few of these have led to exclusive big data analytic programs, cumulatively, with Walgreens, Withings, and Fitbit, involving tens of millions of individuals using mobile device sensors. Community engagement research at the Scripps hub has blossomed with 3 new R01 grants that build on our track record of working with underrepresented minorities in San Diego County and expertise in digital medicine technology. Our inter-hub collaborations and active participation in the CTSA Consortium have markedly increased, as have our educational and training initiatives. We have developed new initiatives to further enhance workforce diversity and entrepreneurial training. These efforts are newly complemented by the Scripps Research Biosciences College that will begin enrolling undergraduate students for a baccalaureate degree next year.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = -$480,111 )
2024	2022	SCRIPPS RESEARCH INSTITUTE	10550 N TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	National Center for Advancing Translational Sciences	000	5	2/20/2024	NON-COMPETING CONTINUATION	-$469,339
2024	2022	SCRIPPS RESEARCH INSTITUTE	10550 N TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Trans-NIH Research Support	001	5	2/20/2024	SUPPLEMENT FOR EXPANSION	-$10,772
														Subtotal = -$480,111

Issue Date FY: 2022 ( Subtotal = $5,891,543 )
2022	2022	SCRIPPS RESEARCH INSTITUTE, THE	10550 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Trans-NIH Research Support	002	5	9/22/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2022	SCRIPPS RESEARCH INSTITUTE, THE	10550 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Trans-NIH Research Support	001	5	8/30/2022	SUPPLEMENT FOR EXPANSION	$132,182
2022	2022	SCRIPPS RESEARCH INSTITUTE, THE	10550 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	National Center for Advancing Translational Sciences	000	5	4/29/2022	NON-COMPETING CONTINUATION	$5,759,361
														Subtotal = $5,891,543

Issue Date FY: 2021 ( Subtotal = $5,759,361 )
2021	2021	SCRIPPS RESEARCH INSTITUTE, THE	10550 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	National Center for Advancing Translational Sciences	002	4	6/21/2021	NON-COMPETING CONTINUATION	$0
2021	2021	SCRIPPS RESEARCH INSTITUTE, THE	10550 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	National Center for Advancing Translational Sciences	001	4	5/4/2021	NON-COMPETING CONTINUATION	$5,759,361
2021	2020	SCRIPPS RESEARCH INSTITUTE, THE	10550 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	National Center for Advancing Translational Sciences	000	3	1/12/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $5,759,361

Issue Date FY: 2020 ( Subtotal = $5,823,036 )
2020	2020	SCRIPPS RESEARCH INSTITUTE, THE	10550 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	National Center for Advancing Translational Sciences	003	3	8/19/2020	SUPPLEMENT FOR EXPANSION	$0
2020	2020	SCRIPPS RESEARCH INSTITUTE, THE	10550 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Trans-NIH Research Support	004	3	9/9/2020	SUPPLEMENT FOR EXPANSION	$0
2020	2020	SCRIPPS RESEARCH INSTITUTE, THE	10550 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	National Center for Advancing Translational Sciences	001	3	5/29/2020	SUPPLEMENT FOR EXPANSION	$182,678
2020	2020	SCRIPPS RESEARCH INSTITUTE, THE	10550 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Trans-NIH Research Support	002	3	8/8/2020	SUPPLEMENT FOR EXPANSION	$97,819
2020	2020	SCRIPPS RESEARCH INSTITUTE, THE	10550 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	National Center for Advancing Translational Sciences	000	3	5/5/2020	NON-COMPETING CONTINUATION	$5,542,539
														Subtotal = $5,823,036

Issue Date FY: 2019 ( Subtotal = $5,586,301 )
2019	2019	SCRIPPS RESEARCH INSTITUTE, THE	10550 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	National Center for Advancing Translational Sciences	001	2	6/11/2019	NON-COMPETING CONTINUATION	$5,562,075
2019	2018	SCRIPPS RESEARCH INSTITUTE, THE	10550 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	National Center for Advancing Translational Sciences	000	1	5/24/2019	NEW	$24,226
														Subtotal = $5,586,301

Issue Date FY: 2018 ( Subtotal = $5,824,976 )
2018	2018	SCRIPPS RESEARCH INSTITUTE, THE	10550 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	National Center for Advancing Translational Sciences	000	1	4/19/2018	NEW	$5,824,976
														Subtotal = $5,824,976

Grand Total All Awards = $28,405,106

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Scripps Translational Science Institute

Award Number: UL1TR002550

ORGANIZATION: NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SOCIAL SERVICES

PERIOD OF PERFORMANCE START DATE: 05/01/2018

PERIOD OF PERFORMANCE END DATE: 06/30/2023

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