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 | Issue Date FY: 2022 ( Subtotal = $251,189,536 ) (Continued on the next page) |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL148096 | Novel functions of Thrombin Activatable Fibrinolysis Inhibitor (TAFI) | 001 | 3 | NIH | 6/8/2022 | $65,143 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL148096 | Novel functions of Thrombin Activatable Fibrinolysis Inhibitor (TAFI) | 000 | 3 | NIH | 4/8/2022 | $586,282 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG066750 | Compound repositioning for Alzheimer's Disease using knowledge graphs, insurance claims data, and gene expression complementarity | 001 | 3 | NIH | 5/3/2022 | $88,654 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01CA042056 | Antitumor Antibiotics | 000 | 38 | NIH | 4/20/2022 | $422,559 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | P60AA006420 | CNS Effects of Alcohol: Cellular Neurobiology | 001 | 39 | NIH | 7/13/2022 | $180,937 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | P60AA006420 | CNS Effects of Alcohol: Cellular Neurobiology | 000 | 39 | NIH | 12/22/2021 | $1,628,418 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL081046 | Regulation of cellular functions by the plasminogen receptor, Plg-RKT | 000 | 16 | NIH | 4/30/2022 | $443,750 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01GM069832 | AutoDock Suite: High Performance Software Environment for Drug Design | 001 | 18 | NIH | 7/28/2022 | $523,910 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | OT2CA278692 | eDyNAmiC - SCRIPPS | 000 | 1 | NIH | 6/24/2022 | $332,321 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG077046 | Analysis of protein interactions in neurodegenerative disease | 000 | 1 | NIH | 4/26/2022 | $693,264 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI167716 | B cell lineage directed rational vaccine strategies based on CAP256SU Env-Ab coevolution | 000 | 1 | NIH | 5/3/2022 | $881,590 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG076745 | Mechanisms of Mutant Prion Protein Aggregation Within Endolysosomal Pathways | 000 | 1 | NIH | 5/6/2022 | $726,467 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | U19AI171443 | Center for Antiviral Medicines & Pandemic Preparedness (CAMPP) | 000 | 1 | NIH | 5/16/2022 | $67,624,156 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R33NS116211 | Develop pan-specific antibody against mutant glycyl-tRNA synthetase for treating CMT2D | 000 | 2 | NIH | 12/30/2021 | $443,750 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21AI170555 | Control of HIV-induced MDSC expansion and immunosuppression by cytotoxic lymphocytes | 000 | 1 | NIH | 8/1/2022 | $266,250 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21NS126916 | Mapping glycan-dependent neurexin interactomes | 000 | 1 | NIH | 8/2/2022 | $310,625 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AA021667 | Excessive alcohol intake and Alzheimer Disease: behavioral and mechanistic studies | 001 | 9 | NIH | 8/12/2022 | $442,914 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AA021667 | Excessive alcohol intake and Alzheimer Disease: behavioral and mechanistic studies | 000 | 9 | NIH | 7/25/2022 | $487,262 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21AI171697 | Modulation of in vivo MAIT cell responses with diverse MR1 ligands | 000 | 1 | NIH | 5/24/2022 | $266,250 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DA046204 | Identification of small molecules for neurological complications of HIV and substance abuse comorbidity | 002 | 5 | NIH | 8/4/2022 | $442,914 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DA046204 | Identification of small molecules for neurological complications of HIV and substance abuse comorbidity | 000 | 5 | NIH | 1/7/2022 | $690,173 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DA046204 | Identification of small molecules for neurological complications of HIV and substance abuse comorbidity | 001 | 5 | NIH | 3/25/2022 | $76,686 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL165168 | The CFTR Interactome | 000 | 1 | NIH | 8/5/2022 | $539,068 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21AI169789 | Designing mammarenavirus live vaccines with unbreachable attenuation | 000 | 1 | NIH | 7/12/2022 | $266,250 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R13NS127523 | The SRBR 2022 Meeting: Rhythms of Life - from Molecules to Policy | 001 | 1 | NIH | 7/9/2022 | $3,000 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R13NS127523 | The SRBR 2022 Meeting: Rhythms of Life - from Molecules to Policy | 001 | 1 | NIH | 7/9/2022 | -$3,000 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | RF1AG070775 | Role of PLD3 in nucleic acid recognition and brain function | 000 | 1 | NIH | 8/3/2022 | $1,331,250 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R13NS127523 | The SRBR 2022 Meeting: Rhythms of Life - from Molecules to Policy | 000 | 1 | NIH | 5/13/2022 | $10,000 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R13NS127523 | The SRBR 2022 Meeting: Rhythms of Life - from Molecules to Policy | 000 | 1 | NIH | 5/13/2022 | $18,000 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | RF1AG079517 | Contributions of cell type and exosome signaling to prodromal synaptic and circuit changes in Alzheimer's Disease models | 000 | 1 | NIH | 8/12/2022 | $2,560,108 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | F99NS129169 | Investigating the pathomechanisms underlying Charcot-Marie-Tooth Disease | 002 | 1 | NIH | 6/14/2022 | $0 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | F99NS129169 | Investigating the pathomechanisms underlying Charcot-Marie-Tooth Disease | 000 | 1 | NIH | 5/27/2022 | $34,752 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | F99NS129169 | Investigating the pathomechanisms underlying Charcot-Marie-Tooth Disease | 001 | 1 | NIH | 6/14/2022 | -$34,752 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | F99NS129169 | Investigating the pathomechanisms underlying Charcot-Marie-Tooth Disease | 001 | 1 | NIH | 6/14/2022 | $34,752 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21DA053443 | Cocaine-motivated behaviors: development of novel viral-based strategies to target orexinergic input to the infralimbic cortex. | 000 | 1 | NIH | 7/25/2022 | $282,489 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21AI166497 | Discovering modulators of exonucleases PLD3 and PLD4 for immunoregulation | 000 | 1 | NIH | 5/10/2022 | $266,250 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM146865 | Methods and approaches to expand the pharmacological toolset | 000 | 1 | NIH | 8/8/2022 | $443,750 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | RF1MH126719 | Ribo-STAMPEDE: novel tools for molecular profiling of brain cell types | 000 | 1 | NIH | 7/22/2022 | $2,308,022 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | K99AA029167 | Mechanisms for predisposition to AUD following prenatal alcohol and THC comorbidity | 000 | 1 | NIH | 4/6/2022 | $143,856 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | F31GM145186 | Allosteric Pharmacologic Chaperones for alpha-1 Antitrypsin Mutants | 000 | 1 | NIH | 2/1/2022 | $33,036 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | F31GM145186 | Allosteric Pharmacologic Chaperones for alpha-1 Antitrypsin Mutants | 002 | 1 | NIH | 6/8/2022 | $716 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | F31GM145186 | Allosteric Pharmacologic Chaperones for alpha-1 Antitrypsin Mutants | 001 | 1 | NIH | 5/25/2022 | $0 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | P01AI168251 | Broadly Effective HCV Vaccine | 000 | 1 | NIH | 1/28/2022 | $2,102,903 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01ES031863 | Early Pathogenic Steps in Xenobiotic-Induced Autoimmunity | 000 | 1 | NIH | 2/24/2022 | $523,588 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21MH129776 | High Throughput Methods for Single Cell Proteomics | 000 | 1 | NIH | 4/12/2022 | $266,250 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AA029841 | Synaptic Mechanisms underlying sex-differences in alcohol use disorder | 000 | 1 | NIH | 4/6/2022 | $399,375 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AA028982 | Alcohol-Induced Neuroinflammation and AUD Therapeutic Mechanisms | 000 | 1 | NIH | 2/28/2022 | $399,375 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | S10OD032467 | High-speed direct detector for cryo electron microscopy | 000 | 1 | NIH | 2/24/2022 | $600,000 |
| | 2022 | 2022 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI167372 | The generation and protective function of lung tissue resident memory T cells following SARS-CoV-2 infection or vaccination | 000 | 1 | NIH | 2/28/2022 | $916,382 |
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