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 | Issue Date FY: 2026 ( Subtotal = $4,130,465 ) |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DK137470 | Pharmacologic targeting of the UPR in obesity-linked liver dysfunction | 000 | 3 | NIH | 12/5/2025 | $766,207 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01CA271500 | Establishing a mechanistic basis for enhanced tumorigenesis under chronic circadian disruption | 000 | 4 | NIH | 12/5/2025 | $546,056 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DK124211 | Molecular mechanisms of transthyretin amyloidosis | 000 | 6 | NIH | 12/18/2025 | $566,635 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI182439 | Chemoproteomic discovery and functional analysis microbiota bile acid-protein targets in host immunity | 000 | 2 | NIH | 12/2/2025 | $919,254 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01NS140965 | Restoring neuronal degradative capacity as a therapeutic strategy to treat Prion Disease | 000 | 2 | NIH | 12/12/2025 | $169,565 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01NS140965 | Restoring neuronal degradative capacity as a therapeutic strategy to treat Prion Disease | 000 | 2 | NIH | 12/12/2025 | $657,581 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM152118 | Sulfur(VI) Fluoride Exchange (SuFEx): new developments and biological applications | 000 | 3 | NIH | 12/10/2025 | $463,680 |
| | 2026 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG070775 | Role of PLD3 in nucleic acid recognition and brain function | 000 | 2 | NIH | 11/21/2025 | $0 |
| | 2026 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG070209 | Using Genetic Diversity to Manage Neurological Disease | 000 | 5 | NIH | 10/15/2025 | $0 |
| | 2026 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | OT2TR005710 | DOGSURF: Database Optimized for Graph Search Using Robust Federation | 000 | 1 | NIH | 11/28/2025 | $0 |
| | 2026 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | P01AI157299 | Eliciting neutralizing antibodies and B cell responses using novel HIV Env immunogens in non-human primates | 000 | 5 | NIH | 11/3/2025 | $0 |
| | 2026 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01GM143805 | Automated, optimized, intelligent data collection for cryo-EM | 000 | 5 | NIH | 12/4/2025 | $0 |
| | 2026 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HG012819 | In vivo Perturb-map: scalable genetic screens with single-cell and spatial resolution in intact tissues | 000 | 3 | NIH | 12/12/2025 | $74,326 |
| | 2026 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | U01AA013498 | 9/10 Electrophysiology of Alcohol in Extended Amygdala | 000 | 24 | NIH | 12/11/2025 | $11,087 |
| | 2026 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AA028879 | Dorsal striatal phosphodiesterase 10A and compulsive ethanol use | 000 | 5 | NIH | 10/7/2025 | $0 |
| | 2026 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01CA262290 | High-Throughput Screen for the Oncoprotein MYC | 000 | 4 | NIH | 11/26/2025 | $0 |
| | 2026 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21AA030807 | Role of glucocorticoid receptor-mediated mRNA decay in alcohol dependence | 000 | 2 | NIH | 11/19/2025 | -$5 |
| | 2026 | 2022 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG056144 | KLF4 in joint degradation and regeneration | 000 | 5 | NIH | 12/1/2025 | $0 |
| | 2026 | 2022 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R13AA017581 | Alcoholism and Stress: A Framework for Future Treatment Strategies | 001 | 8 | NIH | 12/11/2025 | -$43,920 |
| | 2026 | 2022 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R13AA017581 | Alcoholism and Stress: A Framework for Future Treatment Strategies | 000 | 8 | NIH | 10/1/2025 | -$1 |
| | 2026 | 2022 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | RF1MH126719 | Ribo-STAMPEDE: novel tools for molecular profiling of brain cell types | 000 | 1 | NIH | 11/26/2025 | $0 |
| | 2026 | 2021 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R61NS122098 | Identification and Verification of S-Nitrosylated Proteins in Bodily Fluids as Biomarkers for Parkinson's Disease and Lewy Body Dementia | 000 | 1 | NIH | 11/20/2025 | $0 |
|
| Issue Date FY: 2025 ( Subtotal = $159,023,446 ) (Continued on the next page) |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01MH137042 | Scalable functional analysis of neuropsychiatric risk genes with spatially integrated in vivo Perturb-seq | 000 | 2 | NIH | 6/13/2025 | $890,929 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | P01AI157299 | Eliciting neutralizing antibodies and B cell responses using novel HIV Env immunogens in non-human primates | 000 | 5 | NIH | 4/25/2025 | $2,794,109 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL172048 | Molecular pathogenesis of COVID-19-associated coagulopathy and new therapeutic approaches | 001 | 2 | NIH | 3/14/2025 | -$21,000 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | U01DA058399 | Single nucleus gene expression in moderate and compulsive opioid self-administration in a rodent model of HIV | 000 | 3 | NIH | 8/13/2025 | $1,348,437 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL172048 | Molecular pathogenesis of COVID-19-associated coagulopathy and new therapeutic approaches | 000 | 2 | NIH | 12/23/2024 | $659,826 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | UM1AI164561 | Reversing Immune Dysfunction for HIV-1 Eradication | 001 | 5 | NIH | 7/21/2025 | $5,028,890 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AA028879 | Dorsal striatal phosphodiesterase 10A and compulsive ethanol use | 001 | 5 | NIH | 8/19/2025 | $34,650 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AA028879 | Dorsal striatal phosphodiesterase 10A and compulsive ethanol use | 000 | 5 | NIH | 12/13/2024 | $372,600 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG070209 | Using Genetic Diversity to Manage Neurological Disease | 001 | 5 | NIH | 9/23/2025 | $36,800 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG070209 | Using Genetic Diversity to Manage Neurological Disease | 000 | 5 | NIH | 12/5/2024 | $414,000 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01CA294646 | Investigating DNA polymerase O in replication stress and cancer therapy | 001 | 2 | NIH | 8/26/2025 | $610,063 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM152084 | Structure-based in-silico prediction of peptide interactions. | 001 | 2 | NIH | 4/3/2025 | $460,000 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | U01AI160338 | Mechanistic Studies of Combination Adjuvants to Target B Cells in Vaccines | 000 | 5 | NIH | 4/18/2025 | $694,960 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R37AG059418 | FoxO transcription factors in joint aging and osteoarthritis pathogenesis | 003 | 8 | NIH | 6/10/2025 | $36,686 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R37AG059418 | FoxO transcription factors in joint aging and osteoarthritis pathogenesis | 002 | 8 | NIH | 5/2/2025 | $515,710 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI178605 | A NOVEL STRATEGY TO INHIBIT SARS-COV-2 INFECTION AND COVID-19 | 001 | 2 | NIH | 8/19/2025 | -$749,787 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI178605 | A NOVEL STRATEGY TO INHIBIT SARS-COV-2 INFECTION AND COVID-19 | 001 | 2 | NIH | 8/19/2025 | $749,787 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI178605 | A NOVEL STRATEGY TO INHIBIT SARS-COV-2 INFECTION AND COVID-19 | 000 | 2 | NIH | 6/25/2025 | $749,787 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DA059393 | Mapping brain-wide opioid actions by profiling neuronal activities and in vivo cellular target engagement | 000 | 3 | NIH | 7/8/2025 | $830,063 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21EB036298 | Development of potent and safe CRISPR tools for in vivo gene editing using directed evolution | 000 | 2 | NIH | 4/30/2025 | $230,000 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | K12TR004410 | CTSA K12 Program at The Scripps Research Institute | 000 | 3 | NIH | 6/18/2025 | $971,929 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI177265 | Determinants of HIV-1 innate immune sensing and its role in shaping the lymphoid environment. | 000 | 3 | NIH | 7/23/2025 | $846,223 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DK134609 | Neural Mechanisms of Energy Expenditure-Induced Compensatory Food Intake | 000 | 3 | NIH | 4/29/2025 | $707,310 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21HD119928 | Defining the structure-interactome relationships of the basigin glycoprotein in endometriosis | 000 | 1 | NIH | 7/23/2025 | $506,000 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM158320 | Accelerating Discovery by Merging Kinetics with Data Science Methods in Catalytic Organic Reactions | 000 | 1 | NIH | 7/22/2025 | $582,422 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG070775 | Role of PLD3 in nucleic acid recognition and brain function | 000 | 2 | NIH | 7/29/2025 | $450,798 |
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