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 | Issue Date FY: 2025 ( Subtotal = $68,445,263 ) (Continued on the next page) |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI168232 | RNA Recombination in Coronaviruses | 002 | 4 | NIH | 3/14/2025 | $502,084 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM146865 | Methods and approaches to expand the pharmacological toolset | 000 | 4 | NIH | 6/27/2025 | $460,000 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG078756 | Crosstalk between innate-immunity human microglia and adaptive-immunity Tregs in Alzheimer's disease | 001 | 4 | NIH | 6/20/2025 | $36,800 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG078756 | Crosstalk between innate-immunity human microglia and adaptive-immunity Tregs in Alzheimer's disease | 000 | 4 | NIH | 4/28/2025 | $414,000 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | F31DK141247 | Leveraging in vivo protein tracking to identify novel immune markers associated with obesity driven disease | 001 | 1 | NIH | 4/28/2025 | $0 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | F31DK141247 | Leveraging in vivo protein tracking to identify novel immune markers associated with obesity driven disease | 000 | 1 | NIH | 4/28/2025 | $35,974 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AA029841 | Synaptic Mechanisms underlying sex-differences in alcohol use disorder | 000 | 4 | NIH | 5/29/2025 | $414,000 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI191508 | Investigating the chromatin remodeling functions of polyphosphate condensates in Pseudomonas aeruginosa | 000 | 1 | NIH | 5/7/2025 | $779,915 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DE031044 | Salivary gland ionocyte organization and function during homeostasis, repair, and disease | 000 | 5 | NIH | 5/21/2025 | $604,177 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DE031044 | Salivary gland ionocyte organization and function during homeostasis, repair, and disease | 001 | 5 | NIH | 6/11/2025 | $0 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01NS121223 | Beyond Transcription - microRNA Regulation of Neuronal Development | 000 | 5 | NIH | 3/31/2025 | $662,270 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM139643 | Chemoenzymatic glycan editing for deciphering biological functions of glycans | 002 | 5 | NIH | 6/16/2025 | $66,895 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM139643 | Chemoenzymatic glycan editing for deciphering biological functions of glycans | 001 | 5 | NIH | 1/17/2025 | $711,537 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DK124211 | Molecular mechanisms of transthyretin amyloidosis | 001 | 5 | NIH | 12/2/2024 | $566,635 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI130227 | Targeting Influenza A Virus by a Carbohydrate-inspired Strategy | 001 | 6 | NIH | 12/20/2024 | $446,200 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | P01AI177683 | The Multi-omics Vaccine Evaluation (MOVE) Consortium | 000 | 3 | NIH | 4/4/2025 | $1,796,659 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI136621 | Dissecting Polyclonal Sera to Reveal Correlates of Productive Immune Responses to HIV | 000 | 8 | NIH | 2/13/2025 | $837,382 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | UM1TR004407 | Scripps Clinical and Translational Science Hub | 000 | 3 | NIH | 6/14/2025 | $6,078,076 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01CA280720 | Cancer-specific dependencies within the NuRD chromatin remodeler complex: new targets and chemical tools | 001 | 2 | NIH | 6/2/2025 | $58,031 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01CA280720 | Cancer-specific dependencies within the NuRD chromatin remodeler complex: new targets and chemical tools | 000 | 2 | NIH | 12/13/2024 | $522,287 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01ES031863 | Early Pathogenic Steps in Xenobiotic-Induced Autoimmunity | 000 | 4 | NIH | 11/19/2024 | $542,761 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | F31NS136003 | Investigating the mechanism of decision-making in the mitochondrial Protease YME1 | 000 | 2 | NIH | 1/20/2025 | $35,974 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DK137470 | Pharmacologic targeting of the UPR in obesity-linked liver dysfunction | 000 | 2 | NIH | 11/26/2024 | $689,587 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM152084 | Structure-based in-silico prediction of peptide interactions. | 001 | 2 | NIH | 4/3/2025 | $460,000 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | U01AI160338 | Mechanistic Studies of Combination Adjuvants to Target B Cells in Vaccines | 000 | 5 | NIH | 4/18/2025 | $694,960 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | P01AI157299 | Eliciting neutralizing antibodies and B cell responses using novel HIV Env immunogens in non-human primates | 000 | 5 | NIH | 4/25/2025 | $2,794,109 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | U19AI135995 | Center for Viral Systems Biology (CViSB) | 000 | 8 | NIH | 2/18/2025 | $2,568,706 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL172048 | Molecular pathogenesis of COVID-19-associated coagulopathy and new therapeutic approaches | 001 | 2 | NIH | 3/14/2025 | -$21,000 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL172048 | Molecular pathogenesis of COVID-19-associated coagulopathy and new therapeutic approaches | 000 | 2 | NIH | 12/23/2024 | $659,826 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AA028879 | Dorsal striatal phosphodiesterase 10A and compulsive ethanol use | 000 | 5 | NIH | 12/13/2024 | $372,600 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | U01DA056004 | Single nucleus gene expression in moderate and compulsive drug self-administration in a rodent model of HIV | 001 | 4 | NIH | 4/4/2025 | $65,374 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | U01DA056004 | Single nucleus gene expression in moderate and compulsive drug self-administration in a rodent model of HIV | 000 | 4 | NIH | 12/20/2024 | $588,372 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG070209 | Using Genetic Diversity to Manage Neurological Disease | 000 | 5 | NIH | 12/5/2024 | $414,000 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM151347 | Innate lymphocyte responses to early-life infections | 000 | 3 | NIH | 5/19/2025 | $460,000 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI167372 | The generation and protective function of lung tissue resident memory T cells following SARS-CoV-2 infection or vaccination | 000 | 4 | NIH | 2/24/2025 | $863,551 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DC021238 | Decoding vomeronasal activity through awake, behaving AOB imaging. | 001 | 2 | NIH | 5/16/2025 | $72,318 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DC021238 | Decoding vomeronasal activity through awake, behaving AOB imaging. | 000 | 2 | NIH | 2/20/2025 | $650,876 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | K12TR004410 | CTSA K12 Program at The Scripps Research Institute | 000 | 3 | NIH | 6/18/2025 | $971,929 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DK134609 | Neural Mechanisms of Energy Expenditure-Induced Compensatory Food Intake | 000 | 3 | NIH | 4/29/2025 | $707,310 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | F32NS136266 | How does mechanosensation contribute to choroid plexus function in health and disease? | 000 | 2 | NIH | 5/23/2025 | $78,040 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21EB036298 | Development of potent and safe CRISPR tools for in vivo gene editing using directed evolution | 000 | 2 | NIH | 4/30/2025 | $230,000 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R37AG059418 | FoxO transcription factors in joint aging and osteoarthritis pathogenesis | 002 | 8 | NIH | 5/2/2025 | $515,710 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R37AG059418 | FoxO transcription factors in joint aging and osteoarthritis pathogenesis | 003 | 8 | NIH | 6/10/2025 | $36,686 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI178605 | A NOVEL STRATEGY TO INHIBIT SARS-COV-2 INFECTION AND COVID-19 | 000 | 2 | NIH | 6/25/2025 | $749,787 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DK137675 | An Innovative Approach to Identify Correctors of Metabolic Complications in HIV | 001 | 2 | NIH | 6/11/2025 | $82,949 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DK137675 | An Innovative Approach to Identify Correctors of Metabolic Complications in HIV | 002 | 2 | NIH | 6/16/2025 | $9,559 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DK137675 | An Innovative Approach to Identify Correctors of Metabolic Complications in HIV | 000 | 2 | NIH | 12/2/2024 | $832,564 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HG012819 | In vivo Perturb-map: scalable genetic screens with single-cell and spatial resolution in intact tissues | 000 | 3 | NIH | 12/30/2024 | $668,947 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | RF1AG046495 | Discovering Small Molecule Activators of Stress-Responsive Signaling | 000 | 11 | NIH | 10/28/2024 | $169,455 |
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