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 | Issue Date FY: 2026 ( Subtotal = $31,079,897 ) (Continued on the next page) |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DK124211 | Molecular mechanisms of transthyretin amyloidosis | 000 | 6 | NIH | 12/18/2025 | $566,635 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01CA271500 | Establishing a mechanistic basis for enhanced tumorigenesis under chronic circadian disruption | 000 | 4 | NIH | 12/5/2025 | $546,056 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI192143 | Advancing HIV Vaccine Development with a Lipid Nanodisc Platform | 000 | 1 | NIH | 2/13/2026 | $511,531 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI181784 | Combining membrane Env vaccine regimens to elicit multiple bnAb lineages and consistent cross-neutralization of HIV | 000 | 3 | NIH | 12/29/2025 | $940,820 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI182439 | Chemoproteomic discovery and functional analysis microbiota bile acid-protein targets in host immunity | 000 | 2 | NIH | 12/2/2025 | $919,254 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI183472 | Leveraging membrane Env liposome vaccine design to elicit multi-target cross-neutralization of HIV | 000 | 3 | NIH | 2/20/2026 | $868,899 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI167372 | The generation and protective function of lung tissue resident memory T cells following SARS-CoV-2 infection or vaccination | 000 | 5 | NIH | 1/30/2026 | $890,260 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI168917 | Understanding human antibody responses to chronic viral hepatitis C | 000 | 5 | NIH | 1/8/2026 | $637,216 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI167003 | In vivo engineering of B cells for the secretion of HIV broadly neutralizing antibodies | 001 | 5 | NIH | 12/24/2025 | $145,896 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI167003 | In vivo engineering of B cells for the secretion of HIV broadly neutralizing antibodies | 000 | 5 | NIH | 12/23/2025 | $571,808 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI175489 | "Extended dosing" immunization to enhance humoral immunity to next-generation vaccines | 000 | 4 | NIH | 1/15/2026 | $125,528 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI175489 | "Extended dosing" immunization to enhance humoral immunity to next-generation vaccines | 000 | 4 | NIH | 1/15/2026 | $352,082 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI172915 | Microbiota, Probiotic and Dietary Metabolite Control of Enteric Pathogen Virulence | 000 | 4 | NIH | 12/23/2025 | $799,773 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI130227 | Targeting Influenza A Virus by a Carbohydrate-inspired Strategy | 000 | 7 | NIH | 1/21/2026 | $460,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI136621 | Dissecting Polyclonal Sera to Reveal Correlates of Productive Immune Responses to HIV | 000 | 9 | NIH | 3/2/2026 | $863,280 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG046495 | Discovering Small Molecule Activators of Stress-Responsive Signaling | 000 | 12 | NIH | 3/20/2026 | $905,683 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AA028982 | Alcohol-Induced Neuroinflammation and AUD Therapeutic Mechanisms | 000 | 5 | NIH | 3/25/2026 | $414,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AA029841 | Synaptic Mechanisms underlying sex-differences in alcohol use disorder | 000 | 5 | NIH | 3/30/2026 | $414,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | P01AI168251 | Broadly Effective HCV Vaccine | 000 | 5 | NIH | 1/15/2026 | $2,111,046 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | OT2TR005710 | DOGSURF: Database Optimized for Graph Search Using Robust Federation | 001 | 1 | NIH | 12/23/2025 | $1,746,403 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | K00AA031926 | Role of parasubthalamic astrocytic dysfunction in alcohol use disorder | 000 | 4 | NIH | 2/6/2026 | $97,826 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | F31NS141616 | PQBP1 as a central regulator of inflammation in neurodegenerative diseases | 000 | 2 | NIH | 1/14/2026 | $36,538 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | U01AA013498 | 9/10 Electrophysiology of Alcohol in Extended Amygdala | 001 | 25 | NIH | 2/6/2026 | $679,978 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | U01DA056004 | Single nucleus gene expression in moderate and compulsive drug self-administration in a rodent model of HIV | 000 | 5 | NIH | 2/9/2026 | $653,746 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R61AI197037 | A Single Long-Acting Injection For HBV Treatment Using Novel Entecavir Prodrugs For PWLH | 000 | 1 | NIH | 3/30/2026 | $899,741 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R37DA015648 | Modulating Signaling Endocannabinoids and Fatty Acid Amides | 000 | 20 | NIH | 2/5/2026 | $414,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35HL184173 | The protein C pathway: Mechanisms, Structure-function, and Translation | 000 | 1 | NIH | 4/3/2026 | $863,954 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM145323 | Synthesis at the Interface of Chemistry and Biology | 000 | 5 | NIH | 4/2/2026 | $732,320 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM152084 | Structure-based in-silico prediction of peptide interactions. | 000 | 3 | NIH | 3/30/2026 | $460,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM152118 | Sulfur(VI) Fluoride Exchange (SuFEx): new developments and biological applications | 000 | 3 | NIH | 12/10/2025 | $463,680 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21AI185735 | Germline targeting for neuraminidase broadly neutralizing antibodies | 000 | 2 | NIH | 1/21/2026 | $276,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R03AI196996 | Proximal regulation of innate immune signals in ischemia reperfusion injury | 000 | 1 | NIH | 3/30/2026 | $184,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01NS140755 | Post-transcriptional mechanisms of interneuron development | 000 | 1 | NIH | 1/27/2026 | $710,155 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01NS140965 | Restoring neuronal degradative capacity as a therapeutic strategy to treat Prion Disease | 001 | 2 | NIH | 3/24/2026 | $73,065 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01NS140965 | Restoring neuronal degradative capacity as a therapeutic strategy to treat Prion Disease | 001 | 2 | NIH | 3/24/2026 | $18,840 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01NS140965 | Restoring neuronal degradative capacity as a therapeutic strategy to treat Prion Disease | 000 | 2 | NIH | 12/12/2025 | $657,581 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01NS140965 | Restoring neuronal degradative capacity as a therapeutic strategy to treat Prion Disease | 000 | 2 | NIH | 12/12/2025 | $169,565 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01MH141429 | Structural remodeling of neural circuits via multisynaptic boutons | 000 | 1 | NIH | 3/13/2026 | $878,601 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL169631 | Managing Alpha-1-Antitrypsin Deficiency (AATD) through Proteostasis Signaling Pathways | 001 | 3 | NIH | 3/25/2026 | $26,193 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL172048 | Molecular pathogenesis of COVID-19-associated coagulopathy and new therapeutic approaches | 001 | 3 | NIH | 3/23/2026 | $21,294 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL169631 | Managing Alpha-1-Antitrypsin Deficiency (AATD) through Proteostasis Signaling Pathways | 000 | 3 | NIH | 2/27/2026 | $829,501 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL172048 | Molecular pathogenesis of COVID-19-associated coagulopathy and new therapeutic approaches | 000 | 3 | NIH | 3/6/2026 | $674,316 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL166410 | Applying Spatial Covariance to Understand Human Variation in Genetic Disease | 000 | 4 | NIH | 3/19/2026 | $460,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HG012819 | In vivo Perturb-map: scalable genetic screens with single-cell and spatial resolution in intact tissues | 001 | 4 | NIH | 4/2/2026 | $765,499 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01EY035333 | Investigating the anti-inflammatory mechanisms of calorie restriction in the aged lacrimal gland | 000 | 3 | NIH | 4/2/2026 | $688,585 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DK137675 | An Innovative Approach to Identify Correctors of Metabolic Complications in HIV | 000 | 3 | NIH | 12/22/2025 | $930,383 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DK137470 | Pharmacologic targeting of the UPR in obesity-linked liver dysfunction | 000 | 3 | NIH | 12/5/2025 | $766,207 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01ES031863 | Early Pathogenic Steps in Xenobiotic-Induced Autoimmunity | 000 | 5 | NIH | 1/16/2026 | $542,761 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DC021238 | Decoding vomeronasal activity through awake, behaving AOB imaging. | 000 | 3 | NIH | 2/10/2026 | $723,194 |
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