| | | | | | | | | | | | | | | | |
| | |
 | Issue Date FY: 2024 ( Subtotal = $50,123,362 ) (Continued on the next page) |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | P01AI168251 | Broadly Effective HCV Vaccine | 001 | 3 | NIH | 4/11/2024 | $208,354 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | P01AI168251 | Broadly Effective HCV Vaccine | 000 | 3 | NIH | 1/23/2024 | $1,875,174 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI167372 | The generation and protective function of lung tissue resident memory T cells following SARS-CoV-2 infection or vaccination | 000 | 3 | NIH | 2/22/2024 | $796,397 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI167003 | In vivo engineering of B cells for the secretion of HIV broadly neutralizing antibodies | 000 | 3 | NIH | 11/13/2023 | $660,269 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | OT2TR003427 | BioThings Explorer: A platform for distributed knowledge integration across biomedical APIs | 002 | 1 | NIH | 1/17/2024 | $0 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | OT2TR003427 | BioThings Explorer: A platform for distributed knowledge integration across biomedical APIs | 001 | 1 | NIH | 12/8/2023 | $1,062,675 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | OT2TR003445 | Expanding the landscape of Translator Knowledge Providers using BioThings SDK and SmartAPI | 002 | 1 | NIH | 2/14/2024 | $0 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | OT2TR003445 | Expanding the landscape of Translator Knowledge Providers using BioThings SDK and SmartAPI | 001 | 1 | NIH | 12/5/2023 | $561,644 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | OT2TR003427 | BioThings Explorer: A platform for distributed knowledge integration across biomedical APIs | 003 | 1 | NIH | 2/14/2024 | $0 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI150885 | High-throughput assays and small-molecule discovery of antiviral candidates targeting influenza hemagglutinin | 000 | 4 | NIH | 4/9/2024 | $691,905 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | U01AI160338 | Mechanistic Studies of Combination Adjuvants to Target B Cells in Vaccines | 000 | 4 | NIH | 2/15/2024 | $618,445 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM141868 | Investigating DNA double-strand break repair mechanisms in mammalian cells | 003 | 4 | NIH | 1/5/2024 | $407,250 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01NS121223 | Beyond Transcription - microRNA Regulation of Neuronal Development | 000 | 4 | NIH | 3/21/2024 | $651,472 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01NS121223 | Beyond Transcription - microRNA Regulation of Neuronal Development | 001 | 4 | NIH | 4/10/2024 | $50,670 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM139643 | Chemoenzymatic glycan editing for deciphering biological functions of glycans | 002 | 4 | NIH | 1/16/2024 | $700,589 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AA028879 | Dorsal striatal phosphodiesterase 10A and compulsive ethanol use | 000 | 4 | NIH | 12/18/2023 | $366,525 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | P01AI157299 | Eliciting neutralizing antibodies and B cell responses using novel HIV Env immunogens in non-human primates | 000 | 4 | NIH | 1/18/2024 | $3,098,418 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | P01AI157299 | Eliciting neutralizing antibodies and B cell responses using novel HIV Env immunogens in non-human primates | 001 | 4 | NIH | 4/17/2024 | $344,265 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01EY031597 | Experience-dependent Cellular Plasticity Mechanisms | 000 | 4 | NIH | 1/30/2024 | $697,214 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG070209 | Using Genetic Diversity to Manage Neurological Disease | 001 | 4 | NIH | 12/19/2023 | $407,250 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG067331 | Lowering Mitochondrial ATP Synthase Activity Slows Aging and Alzheimer's Disease | 000 | 5 | NIH | 4/16/2024 | $910,978 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM136412 | Dynamics of the Bacterial Ribosome and Proteome | 004 | 5 | NIH | 3/6/2024 | $642,217 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL169631 | Managing Alpha-1-Antitrypsin Deficiency (AATD) through Proteostasis Signaling Pathways | 000 | 1 | NIH | 3/1/2024 | $784,526 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL172048 | Molecular pathogenesis of COVID-19-associated coagulopathy and new therapeutic approaches | 000 | 1 | NIH | 12/26/2023 | $650,342 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01CA280720 | Cancer-specific dependencies within the NuRD chromatin remodeler complex: new targets and chemical tools | 000 | 1 | NIH | 12/28/2023 | $570,856 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DK137470 | Pharmacologic targeting of the UPR in obesity-linked liver dysfunction | 000 | 1 | NIH | 1/4/2024 | $753,715 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | K99CA290143 | Discovering and Characterizing Druggable Cysteines in Cancer Dependency Proteins | 000 | 1 | NIH | 4/2/2024 | $165,780 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21AI178437 | Elucidation of the interactome for the bioactive disaccharide Man(B1-4)GlcNAc | 000 | 1 | NIH | 1/8/2024 | $244,350 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM152084 | Structure-based in-silico prediction of peptide interactions. | 000 | 1 | NIH | 2/16/2024 | $434,750 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | F32CA288144 | Elucidation of the Mechanism of Microhomology-Mediated End Joining by DNA Polymerase Theta | 000 | 1 | NIH | 3/26/2024 | $69,500 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI181784 | Combining membrane Env vaccine regimens to elicit multiple bnAb lineages and consistent cross-neutralization of HIV | 001 | 1 | NIH | 11/13/2023 | $0 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI181784 | Combining membrane Env vaccine regimens to elicit multiple bnAb lineages and consistent cross-neutralization of HIV | 000 | 1 | NIH | 11/1/2023 | $858,153 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DK137675 | An Innovative Approach to Identify Correctors of Metabolic Complications in HIV | 000 | 1 | NIH | 1/15/2024 | $935,900 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI183472 | Leveraging membrane Env liposome vaccine design to elicit multi-target cross-neutralization of HIV | 000 | 1 | NIH | 3/18/2024 | $816,634 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | F32NS136266 | How does mechanosensation contribute to choroid plexus function in health and disease? | 000 | 1 | NIH | 4/18/2024 | $69,500 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM152118 | Sulfur(VI) Fluoride Exchange (SuFEx): new developments and biological applications | 000 | 1 | NIH | 1/29/2024 | $506,800 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | F31NS136003 | Investigating the mechanism of decision-making in the mitochondrial Protease YME1 | 000 | 1 | NIH | 12/29/2023 | $34,694 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | F31NS136003 | Investigating the mechanism of decision-making in the mitochondrial Protease YME1 | 001 | 1 | NIH | 12/29/2023 | $0 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DC021238 | Decoding vomeronasal activity through awake, behaving AOB imaging. | 000 | 1 | NIH | 2/23/2024 | $731,403 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | P01AI177683 | The Multi-omics Vaccine Evaluation (MOVE) Consortium | 000 | 2 | NIH | 4/18/2024 | $1,778,269 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL166410 | Applying Spatial Covariance to Understand Human Variation in Genetic Disease | 000 | 2 | NIH | 4/11/2024 | $452,500 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AT012075 | Deconvolution of Galbulimima bark pharmacology through chemical synthesis and target assignment | 001 | 2 | NIH | 2/23/2024 | $655,042 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21AI171628 | Removing sialic acid ligands of CD28 to enhance T cell cancer immunotherapy | 000 | 2 | NIH | 1/23/2024 | $244,350 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HG012819 | In vivo Perturb-map: scalable genetic screens with single-cell and spatial resolution in intact tissues | 000 | 2 | NIH | 1/16/2024 | $673,738 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DK135080 | Leveraging Human iPSC-derived beta-cells to Probe Antigen Specificity of Anti-islet Memory T Cells in T1D | 000 | 2 | NIH | 1/29/2024 | $740,696 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | F31DK134167 | Molecular mechanism of PIN1-mediated regulation of the nuclear receptor PPARy | 000 | 2 | NIH | 2/14/2024 | $34,694 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21AG080376 | Lifespan extension by reverse fasting | 000 | 2 | NIH | 12/28/2023 | $203,625 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | UM1TR004407 | Scripps Clinical and Translational Science Hub | 001 | 2 | NIH | 4/20/2024 | $6,005,620 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI172915 | Microbiota, Probiotic and Dietary Metabolite Control of Enteric Pathogen Virulence | 001 | 2 | NIH | 4/17/2024 | $63,460 |
|
