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 | Issue Date FY: 2025 ( Subtotal = $3,266,094 ) |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | RF1AG046495 | Discovering Small Molecule Activators of Stress-Responsive Signaling | 000 | 11 | NIH | 10/28/2024 | $169,455 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI181784 | Combining membrane Env vaccine regimens to elicit multiple bnAb lineages and consistent cross-neutralization of HIV | 000 | 2 | NIH | 10/30/2024 | $912,596 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R37DA015648 | Modulating Signaling Endocannabinoids and Fatty Acid Amides | 000 | 19 | NIH | 11/14/2024 | $372,600 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM152118 | Sulfur(VI) Fluoride Exchange (SuFEx): new developments and biological applications | 000 | 2 | NIH | 11/5/2024 | $463,680 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01CA271500 | Establishing a mechanistic basis for enhanced tumorigenesis under chronic circadian disruption | 000 | 3 | NIH | 11/13/2024 | $546,056 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI172915 | Microbiota, Probiotic and Dietary Metabolite Control of Enteric Pathogen Virulence | 000 | 3 | NIH | 10/31/2024 | $775,779 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI167003 | In vivo engineering of B cells for the secretion of HIV broadly neutralizing antibodies | 000 | 4 | NIH | 11/15/2024 | $700,174 |
| | 2025 | 2025 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35NS105067 | Mechanisms of force sensing in the nervous system | 000 | 8 | NIH | 11/15/2024 | $828,000 |
| | 2025 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DK138430 | Intracellular trafficking of the essential signaling metabolite heme in myeloid cells: impact on physiology and disease | 000 | 1 | NIH | 11/14/2024 | $0 |
| | 2025 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | OT2OD035580 | The Participant Center: Empowering All of Us Research Program participation across the United States | 000 | 1 | NIH | 10/31/2024 | $0 |
| | 2025 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM139627 | Link extracellular function of tRNA synthetase with pathological mechanism of disease | 000 | 4 | NIH | 11/5/2024 | $0 |
| | 2025 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM152118 | Sulfur(VI) Fluoride Exchange (SuFEx): new developments and biological applications | 001 | 1 | NIH | 11/15/2024 | $0 |
| | 2025 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM136273 | Defining Genome Stability Mechanisms and their Regulation by SUMO and Ubiquitin | 000 | 5 | NIH | 11/4/2024 | $0 |
| | 2025 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | U01AG088679 | Aberrant protein S-nitrosylation mediates Gene-Environment Interactions in AD/ADRD | 000 | 1 | NIH | 10/22/2024 | $0 |
| | 2025 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35AG071734 | Leadership in AD/ADRD Drug Discovery | 000 | 4 | NIH | 10/21/2024 | $0 |
| | 2025 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | UM1AI144462 | Consortium for HIV/AIDS Vaccine Development | 000 | 6 | NIH | 10/1/2024 | -$149,788 |
| | 2025 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM145323 | Synthesis at the Interface of Chemistry and Biology | 000 | 3 | NIH | 11/11/2024 | $0 |
| | 2025 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM136412 | Dynamics of the Bacterial Ribosome and Proteome | 000 | 5 | NIH | 11/8/2024 | $0 |
| | 2025 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM127090 | Structural and Mechanistic basis for RNA Silencing | 000 | 7 | NIH | 11/6/2024 | $0 |
| | 2025 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM122606 | Unusual Pharmacophores and New Tools for Cross-Coupling | 000 | 8 | NIH | 11/7/2024 | $0 |
| | 2025 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM139643 | Chemoenzymatic glycan editing for deciphering biological functions of glycans | 000 | 4 | NIH | 11/13/2024 | $0 |
| | 2025 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM141868 | Investigating DNA double-strand break repair mechanisms in mammalian cells | 000 | 4 | NIH | 11/13/2024 | $0 |
| | 2025 | 2023 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI145055 | N-glycan baiting to target the highly effective HIV Env shield | 000 | 4 | NIH | 10/29/2024 | $0 |
| | 2025 | 2023 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R61AI161818 | Combining germline-targeting, B cell immunofocusing and Env-Ab coevolution strategies to induce HIV Envelope V2-apex broadly neutralizing antibodies | 001 | 3 | NIH | 10/22/2024 | -$1,134,239 |
| | 2025 | 2023 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21AI170555 | Control of HIV-induced MDSC expansion and immunosuppression by cytotoxic lymphocytes | 000 | 2 | NIH | 10/28/2024 | -$4,793 |
| | 2025 | 2023 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HG010881 | Genotype First: Actionable Genetic Risk through Genotype-to-Phenotype Prediction | 000 | 4 | NIH | 10/17/2024 | $0 |
| | 2025 | 2022 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AA026999 | Pivotal role of thalamic hypocretin transmission during EtOH seeking and relapse | 000 | 5 | NIH | 11/1/2024 | $0 |
| | 2025 | 2022 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R61AI161818 | Combining germline-targeting, B cell immunofocusing and Env-Ab coevolution strategies to induce HIV Envelope V2-apex broadly neutralizing antibodies | 000 | 2 | NIH | 10/22/2024 | -$209,498 |
| | 2025 | 2022 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI142985 | Roles of the Nucleoprotein 3'-5' Exonuclease Domain in Arenavirus Biology | 000 | 4 | NIH | 10/29/2024 | $0 |
| | 2025 | 2022 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG061845 | Neuroprotective Mechanisms of S-Nitrosylated ApoE2 in Aging and Alzheimer's Disease | 000 | 5 | NIH | 10/15/2024 | $0 |
| | 2025 | 2022 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R13AA017581 | Alcoholism and Stress: A Framework for Future Treatment Strategies | 000 | 8 | NIH | 10/1/2024 | -$3,924 |
| | 2025 | 2022 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DA046204 | Identification of small molecules for neurological complications of HIV and substance abuse comorbidity | 000 | 5 | NIH | 11/6/2024 | $0 |
| | 2025 | 2021 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R56AG065372 | Pro-Electrophilic Drugs PEDs for Alzheimer's Disease | 000 | 2 | NIH | 10/15/2024 | $0 |
| | 2025 | 2021 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG056259 | S-Nitrosylation-Induced Posttranslational Modification and Aberrant Cell Signaling in Sporadic Alzheimer's Disease | 000 | 5 | NIH | 10/11/2024 | -$3 |
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| Issue Date FY: 2024 ( Subtotal = $154,153,911 ) (Continued on the next page) |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | K99NS133478 | Functional interrogation of sensory neurons in inflammation | 000 | 2 | NIH | 8/8/2024 | $119,880 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL157566 | Probing the Proteinopathy Component of Light Chain Amyloidosis Pharmacologically | 000 | 4 | NIH | 6/14/2024 | $460,000 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI181784 | Combining membrane Env vaccine regimens to elicit multiple bnAb lineages and consistent cross-neutralization of HIV | 003 | 1 | NIH | 9/6/2024 | $0 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | P01AI172525 | Multidimensional development of high-affinity anti-glycan antibodies to fight deadly bacterial infections | 001 | 2 | NIH | 9/4/2024 | $0 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI181784 | Combining membrane Env vaccine regimens to elicit multiple bnAb lineages and consistent cross-neutralization of HIV | 002 | 1 | NIH | 9/4/2024 | $95,351 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI168917 | Understanding human antibody responses to chronic viral hepatitis C | 000 | 3 | NIH | 12/29/2023 | $564,144 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI181784 | Combining membrane Env vaccine regimens to elicit multiple bnAb lineages and consistent cross-neutralization of HIV | 000 | 1 | NIH | 11/1/2023 | $858,153 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE, THE | 10550 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI181784 | Combining membrane Env vaccine regimens to elicit multiple bnAb lineages and consistent cross-neutralization of HIV | 001 | 1 | NIH | 11/13/2023 | $0 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM139627 | Link extracellular function of tRNA synthetase with pathological mechanism of disease | 001 | 4 | NIH | 6/4/2024 | $460,000 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | P01AI172525 | Multidimensional development of high-affinity anti-glycan antibodies to fight deadly bacterial infections | 000 | 2 | NIH | 5/1/2024 | $1,943,996 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35AG071734 | Leadership in AD/ADRD Drug Discovery | 000 | 4 | NIH | 8/13/2024 | $1,101,512 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01ES031863 | Early Pathogenic Steps in Xenobiotic-Induced Autoimmunity | 000 | 3 | NIH | 11/22/2023 | $533,912 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21AA029498 | PPARdelta receptors and alcohol use phenotypes | 000 | 2 | NIH | 5/13/2024 | $264,500 |
| | 2024 | 2024 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG077046 | Analysis of protein interactions in neurodegenerative disease | 000 | 3 | NIH | 4/26/2024 | $706,934 |
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