| | | | | | | | | | | | | | | | |
| | |
 | Issue Date FY: 2026 ( Subtotal = $111,582,427 ) (Continued on the next page) |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | P01AI172525 | Multidimensional development of high-affinity anti-glycan antibodies to fight deadly bacterial infections | 000 | 4 | NIH | 5/19/2026 | $1,961,391 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01GM148675 | Inhibition or evasion of P-glycoprotein-mediated drug transport | 000 | 4 | NIH | 5/19/2026 | $497,527 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | F30DK145195 | Mapping MicroRNA-target Interactions in the Zonated Liver | 000 | 1 | NIH | 4/8/2026 | $37,114 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21EB036894 | Exploring Entangled Photons for Biomedical Quantum Sensing | 000 | 1 | NIH | 7/21/2026 | $276,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R37AG100304 | Chemical modulation of proteostasis to promote longevity and healthy aging | 000 | 1 | NIH | 6/19/2026 | $645,242 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21TR006406 | Developing oral drugs targeting the insulin receptor using 'Beyond Rule of 5' DEL libraries | 000 | 1 | NIH | 7/28/2026 | $368,500 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL184492 | Engineering functionally addressable direct-acting thrombolytic enzymes | 000 | 1 | NIH | 8/5/2026 | $1,101,338 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | DP2AI200982 | Understanding plasma cell longevity and their roles beyond antibody production | 000 | 1 | NIH | 7/16/2026 | $552,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI201328 | Self-Assembling Protein Nanoparticles Presenting Stabilized Hemagglutinin, Neuraminidase, and M2e Antigens for Universal Influenza Vaccine Development | 000 | 1 | NIH | 8/5/2026 | $3,679,976 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R61AI197037 | A Single Long-Acting Injection For HBV Treatment Using Novel Entecavir Prodrugs For PWLH | 000 | 1 | NIH | 3/30/2026 | $899,741 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21AI199873 | Host-specific profiles of Defective Viral Genomes of influenza virus | 000 | 1 | NIH | 6/23/2026 | $270,443 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R03AI196996 | Proximal regulation of innate immune signals in ischemia reperfusion injury | 000 | 1 | NIH | 3/30/2026 | $184,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21AI199600 | A PROTAC Strategy to Combat Botulinum Neurotoxicity | 000 | 1 | NIH | 6/11/2026 | $518,450 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI198771 | Mechanistic Studies of Combination Adjuvants in the Establishment of B Cell Memory | 000 | 1 | NIH | 7/23/2026 | $772,010 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35HL184173 | The protein C pathway: Mechanisms, Structure-function, and Translation | 000 | 1 | NIH | 4/3/2026 | $863,954 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI200742 | Optimizing vaccine-elicited cross-neutralizing antibody responses to the HIV Env trimer apex | 000 | 1 | NIH | 7/31/2026 | $937,343 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21AI200873 | A Modular Cross-Linker Platform for Proteome-Scale Mapping of Dynamic Protein-Protein Interactions in Cells | 000 | 1 | NIH | 4/28/2026 | $230,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AT013598 | Interoceptive network that co-regulates emotional and autonomic responses | 000 | 1 | NIH | 4/21/2026 | $831,984 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM165767 | Deciphering the molecular principles linking PopZ filament structure to condensate function | 000 | 1 | NIH | 6/23/2026 | $506,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | P01HL183482 | PlanB2CureHIV (the 'PlanB' consortium) | 000 | 2 | NIH | 7/24/2026 | $3,479,555 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01NS140755 | Post-transcriptional mechanisms of interneuron development | 000 | 1 | NIH | 1/27/2026 | $710,155 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01CA304089 | Targeted degradation of glycoimmune checkpoints Siglec-7 and -9 for cancer immunotherapy | 000 | 1 | NIH | 6/23/2026 | $748,410 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI194636 | Targeting the polymerase and endonuclease activities of the L protein of human pathogenic mammarenaviruses | 000 | 1 | NIH | 7/16/2026 | $1,620,145 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI198218 | Dissecting mechanisms of action of next-generation saponin combination adjuvants. | 000 | 1 | NIH | 7/23/2026 | $865,432 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R13AI202922 | Neutrophil 2026: the Eighth Neutrophil International Symposium | 000 | 1 | NIH | 7/24/2026 | $8,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R56AI200473 | Glycoengineering core a(1,3)-fucose motifs to enhance HIV-1 envelope vaccine immunogenicity | 000 | 1 | NIH | 6/11/2026 | $931,385 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI198816 | Antibody-guided design of a human astrovirus vaccine | 000 | 1 | NIH | 6/11/2026 | $919,605 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DA065827 | Stabilized Salvinorin Analogs | 001 | 1 | NIH | 8/4/2026 | $0 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DA065827 | Stabilized Salvinorin Analogs | 000 | 1 | NIH | 7/28/2026 | $740,595 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | DP2AI201038 | Functional characterization of dendritic cell heterogeneity for T cell-inducing immunotherapies | 000 | 1 | NIH | 7/28/2026 | $552,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01MH141429 | Structural remodeling of neural circuits via multisynaptic boutons | 000 | 1 | NIH | 3/13/2026 | $878,601 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM166357 | Decoding membrane protein folding and functional principles using simple designed building blocks | 000 | 1 | NIH | 7/20/2026 | $506,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R61AI197860 | Engineering broadly cross-reactive monobodies to reverse botulinum intoxication | 000 | 1 | NIH | 6/16/2026 | $501,137 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01CA303840 | Chemical inducers of proximity to antagonize FOXA1 | 000 | 1 | NIH | 7/20/2026 | $744,054 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI192143 | Advancing HIV Vaccine Development with a Lipid Nanodisc Platform | 000 | 1 | NIH | 2/13/2026 | $511,531 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI192456 | Engineering durable immunity by optimizing HIV vaccine parameters to drive long-lived plasma cell development | 000 | 2 | NIH | 7/28/2026 | $1,379,954 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG079517 | Contributions of cell type and exosome signaling to prodromal synaptic and circuit changes in Alzheimer's Disease models | 002 | 3 | NIH | 7/24/2026 | $865,877 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DK143190 | Initiation of anti-islet autoimmunity: Regulation of MHC class II expression in the islet microenvironment | 000 | 2 | NIH | 7/8/2026 | $801,662 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DA063157 | Data Mining and Functional Validation of SCORCH Datasets | 000 | 2 | NIH | 6/8/2026 | $608,652 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DC021238 | Decoding vomeronasal activity through awake, behaving AOB imaging. | 000 | 3 | NIH | 2/10/2026 | $723,194 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM158320 | Accelerating Discovery by Merging Kinetics with Data Science Methods in Catalytic Organic Reactions | 000 | 2 | NIH | 7/8/2026 | $460,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG070775 | Role of PLD3 in nucleic acid recognition and brain function | 001 | 3 | NIH | 8/5/2026 | $460,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI192458 | Enhancing durability of V3 glycan vaccine responses in rhesus macaques | 000 | 2 | NIH | 7/29/2026 | $1,242,204 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI167372 | The generation and protective function of lung tissue resident memory T cells following SARS-CoV-2 infection or vaccination | 000 | 5 | NIH | 1/30/2026 | $890,260 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | U19AI135995 | Center for Viral Systems Biology- Outbreak.info | 001 | 9 | NIH | 8/4/2026 | $200,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | U19AI135995 | Center for Viral Systems Biology- Outbreak.info | 001 | 9 | NIH | 8/4/2026 | $206,008 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | U19AI135995 | Center for Viral Systems Biology- Outbreak.info | 000 | 9 | NIH | 4/10/2026 | $2,565,260 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM158311 | Enantioselective and site-selective C-H activation reactions with Bifunctional ligands | 000 | 2 | NIH | 6/19/2026 | $874,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AT013748 | Building a somatosensory atlas for interoception | 000 | 2 | NIH | 5/28/2026 | $2,847,421 |
|
