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 | Issue Date FY: 2026 ( Subtotal = $61,867,109 ) (Continued on the next page) |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI172915 | Microbiota, Probiotic and Dietary Metabolite Control of Enteric Pathogen Virulence | 000 | 4 | NIH | 12/23/2025 | $799,773 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | UG3DK142188 | Studying the mechanisms of initiation and progression of Beta cell death in T1D | 000 | 2 | NIH | 1/20/2026 | $1,203,561 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01ES031863 | Early Pathogenic Steps in Xenobiotic-Induced Autoimmunity | 000 | 5 | NIH | 1/16/2026 | $542,761 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI175489 | "Extended dosing" immunization to enhance humoral immunity to next-generation vaccines | 000 | 4 | NIH | 1/15/2026 | $352,082 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI175489 | "Extended dosing" immunization to enhance humoral immunity to next-generation vaccines | 000 | 4 | NIH | 1/15/2026 | $125,528 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI182439 | Chemoproteomic discovery and functional analysis microbiota bile acid-protein targets in host immunity | 000 | 2 | NIH | 12/2/2025 | $919,254 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI167003 | In vivo engineering of B cells for the secretion of HIV broadly neutralizing antibodies | 000 | 5 | NIH | 12/23/2025 | $571,808 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI167003 | In vivo engineering of B cells for the secretion of HIV broadly neutralizing antibodies | 001 | 5 | NIH | 12/24/2025 | $145,896 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI181784 | Combining membrane Env vaccine regimens to elicit multiple bnAb lineages and consistent cross-neutralization of HIV | 000 | 3 | NIH | 12/29/2025 | $940,820 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI136621 | Dissecting Polyclonal Sera to Reveal Correlates of Productive Immune Responses to HIV | 000 | 9 | NIH | 3/2/2026 | $863,280 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI168917 | Understanding human antibody responses to chronic viral hepatitis C | 000 | 5 | NIH | 1/8/2026 | $637,216 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI192143 | Advancing HIV Vaccine Development with a Lipid Nanodisc Platform | 000 | 1 | NIH | 2/13/2026 | $511,531 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01NS140965 | Restoring neuronal degradative capacity as a therapeutic strategy to treat Prion Disease | 000 | 2 | NIH | 12/12/2025 | $657,581 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01NS140965 | Restoring neuronal degradative capacity as a therapeutic strategy to treat Prion Disease | 000 | 2 | NIH | 12/12/2025 | $169,565 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DK124211 | Molecular mechanisms of transthyretin amyloidosis | 000 | 6 | NIH | 12/18/2025 | $566,635 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM152118 | Sulfur(VI) Fluoride Exchange (SuFEx): new developments and biological applications | 000 | 3 | NIH | 12/10/2025 | $463,680 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DK137470 | Pharmacologic targeting of the UPR in obesity-linked liver dysfunction | 000 | 3 | NIH | 12/5/2025 | $766,207 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01CA271500 | Establishing a mechanistic basis for enhanced tumorigenesis under chronic circadian disruption | 000 | 4 | NIH | 12/5/2025 | $546,056 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R21AI200873 | A Modular Cross-Linker Platform for Proteome-Scale Mapping of Dynamic Protein-Protein Interactions in Cells | 000 | 1 | NIH | 4/28/2026 | $230,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AA029841 | Synaptic Mechanisms underlying sex-differences in alcohol use disorder | 000 | 5 | NIH | 3/30/2026 | $414,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | P01AI177683 | The Multi-omics Vaccine Evaluation (MOVE) Consortium | 000 | 4 | NIH | 4/6/2026 | $1,796,659 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | F32NS136266 | How does mechanosensation contribute to choroid plexus function in health and disease? | 000 | 3 | NIH | 4/27/2026 | $64,285 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01MH141429 | Structural remodeling of neural circuits via multisynaptic boutons | 000 | 1 | NIH | 3/13/2026 | $878,601 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01CA271500 | Establishing a mechanistic basis for enhanced tumorigenesis under chronic circadian disruption | 001 | 4 | NIH | 4/24/2026 | $60,673 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HG012819 | In vivo Perturb-map: scalable genetic screens with single-cell and spatial resolution in intact tissues | 001 | 4 | NIH | 4/2/2026 | $765,499 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01EY035333 | Investigating the anti-inflammatory mechanisms of calorie restriction in the aged lacrimal gland | 000 | 3 | NIH | 4/2/2026 | $688,585 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM130385 | Metabolomics Technologies to Advance Biomedical Research | 000 | 8 | NIH | 4/24/2026 | $460,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM145323 | Synthesis at the Interface of Chemistry and Biology | 000 | 5 | NIH | 4/2/2026 | $732,320 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | U19AI135995 | Center for Viral Systems Biology (CViSB) | 000 | 9 | NIH | 4/10/2026 | $2,565,260 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01CA280720 | Cancer-specific dependencies within the NuRD chromatin remodeler complex: new targets and chemical tools | 001 | 3 | NIH | 4/22/2026 | $58,031 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AA028982 | Alcohol-Induced Neuroinflammation and AUD Therapeutic Mechanisms | 000 | 5 | NIH | 3/25/2026 | $414,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01NS140965 | Restoring neuronal degradative capacity as a therapeutic strategy to treat Prion Disease | 001 | 2 | NIH | 3/24/2026 | $73,065 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01NS140965 | Restoring neuronal degradative capacity as a therapeutic strategy to treat Prion Disease | 001 | 2 | NIH | 3/24/2026 | $18,840 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL169631 | Managing Alpha-1-Antitrypsin Deficiency (AATD) through Proteostasis Signaling Pathways | 001 | 3 | NIH | 3/25/2026 | $26,193 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL172048 | Molecular pathogenesis of COVID-19-associated coagulopathy and new therapeutic approaches | 001 | 3 | NIH | 3/23/2026 | $21,294 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI191508 | Investigating the chromatin remodeling functions of polyphosphate condensates in Pseudomonas aeruginosa | 000 | 2 | NIH | 5/5/2026 | $799,175 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R61AI197037 | A Single Long-Acting Injection For HBV Treatment Using Novel Entecavir Prodrugs For PWLH | 000 | 1 | NIH | 3/30/2026 | $899,741 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | UM1TR004407 | Scripps Clinical and Translational Science Hub | 000 | 4 | NIH | 4/28/2026 | $6,074,495 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35GM152084 | Structure-based in-silico prediction of peptide interactions. | 000 | 3 | NIH | 3/30/2026 | $460,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | K01DK132957 | Deconstructing brainstem circuits for visceral senses | 000 | 4 | NIH | 4/21/2026 | $153,360 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | F30DK145195 | Mapping MicroRNA-target Interactions in the Zonated Liver | 001 | 1 | NIH | 4/8/2026 | $0 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AG088908 | Structure-function studies of DELE1-mediated activation of the integrated stress response | 000 | 3 | NIH | 4/21/2026 | $632,667 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AT013598 | Interoceptive network that co-regulates emotional and autonomic responses | 000 | 1 | NIH | 4/21/2026 | $831,984 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R35HL184173 | The protein C pathway: Mechanisms, Structure-function, and Translation | 000 | 1 | NIH | 4/3/2026 | $863,954 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI130227 | Targeting Influenza A Virus by a Carbohydrate-inspired Strategy | 000 | 7 | NIH | 1/21/2026 | $460,000 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01HL172048 | Molecular pathogenesis of COVID-19-associated coagulopathy and new therapeutic approaches | 000 | 3 | NIH | 3/6/2026 | $674,316 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01AI183472 | Leveraging membrane Env liposome vaccine design to elicit multi-target cross-neutralization of HIV | 000 | 3 | NIH | 2/20/2026 | $868,899 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | R01DK137675 | An Innovative Approach to Identify Correctors of Metabolic Complications in HIV | 000 | 3 | NIH | 12/22/2025 | $930,383 |
| | 2026 | 2026 | SCRIPPS RESEARCH INSTITUTE | 10550 N TORREY PINES RD | LA JOLLA | CA | 92037-1000 | SAN DIEGO | USA | OT2TR005710 | DOGSURF: Database Optimized for Graph Search Using Robust Federation | 001 | 1 | NIH | 12/23/2025 | $1,746,403 |
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