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Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success

Award Number: UL1TR001866
ORGANIZATION: NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SOCIAL SERVICES
PERIOD OF PERFORMANCE START DATE: 07/05/2016
PERIOD OF PERFORMANCE END DATE: 05/31/2027

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Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success - The overall vision of the Rockefeller University Center for Clinical and Translational Science (CCTS), supported by the CTSA program, is to develop, demonstrate, and disseminate innovative programs so as to create a model clinical research enterprise built on rigor, responsible and transparent reporting, and scientific integrity to empower translation of paradigm-breaking discoveries into better human health. Our new initiatives are designed to: 1) ensure that all of our studies set the highest standards; 2) ensure that our trainees have the team science leadership skills needed for a career in translational science; and 3) enhance scientific rigor, reproducibility, and reporting. These new areas build on the infrastructure we have developed to integrate mechanistic science into community engagement, reach out to basic scientists, speed the development of health- enhancing products, and create an optimal training environment. Our specific aims are: 1. To provide a robust infrastructure to support the conduct of clinical investigation at the highest levels of participant safety, scientific rigor, bioethics, and regulatory compliance. We will enhance our multidisciplinary Translational Research Navigation (TRN) Program and our collaboration with Clinical Directors Network (CDN), a Practice Based Research Network of Community Health Centers, to ensure that our studies meet the highest standards of design, feasibility, method validity, and transparent reporting, supporting our active participation in the CTSA Trial Innovation Network. 2. To ensure that every discovery at Rockefeller has the best chance of improving human health. We will enhance our robust pipeline of programs to support basic and clinical investigators move their paradigm-breaking discoveries into new therapeutics by leveraging the resources of the Tri-Institutional Therapeutic Development Institute, the Robertson Therapeutic Development Fund, and the University affiliated biotechnology company, Bridge Medicines .3. To educate the entire research workforce team in conducting translational research at the highest levels of participant safety, scientific rigor, bioethics, and regulatory compliance. We will further enhance the multidisciplinary team science emphasis of our educational programs for KL2 Clinical Scholars, Clinical Research Nurses, basic scientists, and community clinicians, with a focus on our new Team Science Leadership training with the CTSA Hubs at Yale, University of Pennsylvania, and Columbia. 4. To study and improve the clinical research enterprise both at Rockefeller and nationally. We will continue to use the CCTS as a laboratory for investigating the clinical research enterprise itself and methods to improve it, including obtaining outcome data from research participants, enhancing rigor, reproducibility and reporting, speeding the evaluation of novel therapeutics via in-house formulation, and creating 'super teams' of CTSA Hubs to disseminate our model of community engagement harnessing basic mechanistic studies to address community-identified health needs. We will disseminate the results throughout the CTSA consortium and scientific community by publications, presentations, and active participation in CLIC and CD2H initiatives.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2025	ROCKEFELLER UNIVERSITY	1230 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	National Center for Advancing Translational Sciences	000	10	3/25/2026	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2025 ( Subtotal = $3,671,021 )
2025	2025	ROCKEFELLER UNIVERSITY	1230 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	National Center for Advancing Translational Sciences	000	10	5/26/2025	NON-COMPETING CONTINUATION	$3,671,021
														Subtotal = $3,671,021

Issue Date FY: 2024 ( Subtotal = $3,669,160 )
2024	2024	ROCKEFELLER UNIVERSITY	1230 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	National Center for Advancing Translational Sciences	001	9	7/19/2024	NON-COMPETING CONTINUATION	$0
2024	2024	ROCKEFELLER UNIVERSITY	1230 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	National Center for Advancing Translational Sciences	000	9	5/6/2024	NON-COMPETING CONTINUATION	$3,669,160
														Subtotal = $3,669,160

Issue Date FY: 2023 ( Subtotal = $2,775,381 )
2023	2023	ROCKEFELLER UNIVERSITY	1230 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	National Center for Advancing Translational Sciences	000	8	5/23/2023	NON-COMPETING CONTINUATION	$2,775,381
														Subtotal = $2,775,381

Issue Date FY: 2022 ( Subtotal = $3,681,571 )
2022	2022	ROCKEFELLER UNIVERSITY	1230 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	National Center for Advancing Translational Sciences	002	7	5/20/2022	NON-COMPETING CONTINUATION	$3,681,571
2022	2021	ROCKEFELLER UNIVERSITY	1230 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	National Center for Advancing Translational Sciences	001	6	11/2/2021	COMPETING CONTINUATION	$873,040
2022	2020	ROCKEFELLER UNIVERSITY	1230 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	National Center for Advancing Translational Sciences	000	5	11/2/2021	NON-COMPETING CONTINUATION	-$873,040
														Subtotal = $3,681,571

Issue Date FY: 2021 ( Subtotal = $3,671,021 )
2021	2021	ROCKEFELLER UNIVERSITY, THE	1230 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	National Center for Advancing Translational Sciences	000	6	5/27/2021	COMPETING CONTINUATION	$3,671,021
														Subtotal = $3,671,021

Issue Date FY: 2020 ( Subtotal = $3,639,604 )
2020	2020	ROCKEFELLER UNIVERSITY, THE	1230 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	National Center for Advancing Translational Sciences	000	5	5/29/2020	NON-COMPETING CONTINUATION	$3,639,604
														Subtotal = $3,639,604

Issue Date FY: 2019 ( Subtotal = $3,565,806 )
2019	2019	ROCKEFELLER UNIVERSITY, THE	1230 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	National Center for Advancing Translational Sciences	001	4	6/15/2019	NON-COMPETING CONTINUATION	$3,565,806
2019	2018	ROCKEFELLER UNIVERSITY, THE	1230 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	National Center for Advancing Translational Sciences	000	3	11/8/2018	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $3,565,806

Issue Date FY: 2018 ( Subtotal = $4,818,301 )
2018	2018	ROCKEFELLER UNIVERSITY, THE	1230 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	National Center for Advancing Translational Sciences	001	3	9/1/2018	SUPPLEMENT FOR EXPANSION	$484,268
2018	2018	ROCKEFELLER UNIVERSITY, THE	1230 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	National Center for Advancing Translational Sciences	000	3	5/29/2018	NON-COMPETING CONTINUATION	$4,334,033
														Subtotal = $4,818,301

Issue Date FY: 2017 ( Subtotal = $5,151,440 )
2017	2017	ROCKEFELLER UNIVERSITY, THE	1230 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	National Center for Advancing Translational Sciences	000	2	6/15/2017	NON-COMPETING CONTINUATION	$4,636,296
2017	2017	ROCKEFELLER UNIVERSITY, THE	1230 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	National Center for Advancing Translational Sciences	001	2	9/1/2017	NON-COMPETING CONTINUATION	$515,144
														Subtotal = $5,151,440

Issue Date FY: 2016 ( Subtotal = $5,911,836 )
2016	2016	ROCKEFELLER UNIVERSITY	EAST 66TH STREET & YORK AVENUE	NEW YORK	NY	10021	NEW YORK	USA	National Center for Advancing Translational Sciences	000	1	7/5/2016	NEW	$5,911,836
														Subtotal = $5,911,836

Grand Total All Awards = $40,555,141

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Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success

Award Number: UL1TR001866

ORGANIZATION: NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SOCIAL SERVICES

PERIOD OF PERFORMANCE START DATE: 07/05/2016

PERIOD OF PERFORMANCE END DATE: 05/31/2027

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