Nemours is internationally recognized, multi-site pediatric healthcare system that is built upon a
centralized, efficient and collaborative research infrastructure committed to improving the health of all children.
In 2014, with over 25 years' experience in clinical trials research, the four Nemours Center for Cancer and
Blood Disorders (NCCBD) sites received funding as a NCI Community Oncology Research Program dedicated
to children with cancer through participation in the Children's Oncology Group (COG) Research Base trials.
The Nemours Alfred I duPont Hospital for Children (NCCBD-Wilmington, DE), Nemours Children's Clinics
(NCCBD-Jacksonville, Florida), Nemours Children's Hospital (NCCBD-Orlando, FL) and Sacred Heart,
Pensacola, FL all had outstanding records of clinical trial participation and collaboration under the Nemours
NCORP operational structure. In the current application, the Nemours NCORP will add a fifth site, Broward
Heath (Ft. Lauderdale, Florida) to improve the enrollment of minority and underserved patients.
The mission of the Nemours NCORP is to ensure that each child and young adolescent within our
community-based catchment area has the opportunity to participate in national cancer control, cancer
prevention, and cancer treatment trials as appropriate. The Nemours NCORP will continue to sustain systems
supportive of cancer control, cancer prevention, care delivery, and treatment research, as well as to maintain
robust quality management and improvement practices. Through Nemours' already well-established network of
healthcare institutions, community-based physician practices, and strong community ties, we will continue to
extend access to research trials to children from all ethnicities and cultural backgrounds. Inclusive of all sites,
the Nemours NCORP is consistently among the highest enrolling contributors to the Children's Oncology
Group Research Base studies, providing the opportunity to learn from all children with ultra-rare diseases. The
Nemours NCORP will continue and grow a childhood cancer research infrastructure that achieves the following
aims: 1) To ensure continued robust accrual to NCI-funded clinical trials, through the meaningful use of
electronic resources and best practices across the continuum of care, 2) To expand and maintain an
infrastructure supportive of productive and efficient participation in NCI-funded Cancer Care
Prevention (CCP) and Care Delivery (CD) Research (CCDR), and 3) To foster community engagement
through dissemination, discussion, and adoption of results from clinical trials, and through physician,
family, and community education.