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ECOG-ACRIN NCORP Research Base

Award Number: UG1CA189828
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Project Summary The ECOG-ACRIN Cancer Research Group (EA) is dedicated to decreasing the burden of cancer. EA is a vibrant member of the National Clinical Trials Network (NCTN) and the NCI Community Oncology Research Program (NCORP), focused on practice-changing clinical and translational research across the cancer care continuum from prevention and early detection, through the management of advanced disease and its impact. As an NCORP Research Base, EA has engaged community providers and researchers to develop a robust research portfolio that spans Cancer Prevention, Cancer Control, and Cancer Care Delivery, aligned with the overall scientific themes of precision oncology, immuno-oncology, reducing overdiagnosis and overtreatment, and leveraging novel biomarker platforms. Cancer control trials examine and intervene on challenges associated with cancer and treatment-related symptoms and concerns. EA's portfolio of therapeutic trials yield opportunities to apply patient-reported outcomes measurement science to quantify health-related quality of life, symptoms, and domains most relevant to patients in the context of evolving treatment paradigms. Behavioral and biomarker-driven symptom interventions aim to improve quality of life and cancer survivorship. Cardiotoxicity research aims to mitigate risk through quantifying cardiotoxicity associated with treatment, identifying groups at risk, and advancing interventions to reduce risk. Prevention trials embrace the NCI's broad definition of prevention to include primary prevention, cancer screening, and secondary prevention and aim to identify high risk groups for precision prevention strategies. Cancer Care Delivery Research (CCDR) examines the complex interactions between patient, provider, and system factors that influence care, and adapts and evaluates interventions in heterogenous community oncology practices. Health equity research permeates EA science through embedding disparities-related research questions that span EA activities, adopting a broad view of underserved populations including adolescents and young adults, the elderly, racial and ethnic minorities, sexual and gender minorities and rural residents. Key collaborations with community-based oncology programs will ensure access to EA NCTN and NCORP trials in communities where patients receive their care. EA provides access to existing NCI-funded resources and a network of >10000 physicians, scientists, nurses, research associates (RAs), statisticians, biomedical information technologists, and patient advocates across approximately 600 institutions and organizations. EA has provided scientific leadership in the NCORP community through advancing rigorous, practice-changing clinical trials and translational research in cancer control, prevention and care delivery and is well poised to continue to support the NCI's mission to engage community-based diverse populations in cancer research.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2024	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	000	11	10/29/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $18,695,221 )
2024	2024	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	000	11	7/30/2024	NON-COMPETING CONTINUATION	$5,087,073
2024	2024	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	001	11	9/19/2024	NON-COMPETING CONTINUATION	$13,608,148
														Subtotal = $18,695,221

Issue Date FY: 2023 ( Subtotal = $23,577,915 )
2023	2023	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	000	10	8/18/2023	NON-COMPETING CONTINUATION	$5,154,867
2023	2023	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	001	10	9/19/2023	SUPPLEMENT FOR EXPANSION	$18,423,048
														Subtotal = $23,577,915

Issue Date FY: 2022 ( Subtotal = $27,625,329 )
2022	2022	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Treatment Research	002	8	5/2/2022	SUPPLEMENT FOR EXPANSION	$945,901
2022	2022	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	007	9	9/19/2022	SUPPLEMENT FOR EXPANSION	$322,207
2022	2022	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	005	9	9/13/2022	NON-COMPETING CONTINUATION	$7,295,153
2022	2022	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	006	9	9/14/2022	NON-COMPETING CONTINUATION	$18,919,381
2022	2021	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Treatment Research	001	8	1/24/2022	SUPPLEMENT FOR EXPANSION	$142,687
2022	2021	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	003	8	5/11/2022	NON-COMPETING CONTINUATION	$0
2022	2021	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	000	8	12/27/2021	NON-COMPETING CONTINUATION	$0
2022	2018	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Treatment Research	004	5	8/26/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $27,625,329

Issue Date FY: 2021 ( Subtotal = $7,974,153 )
2021	2021	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	001	8	7/30/2021	NON-COMPETING CONTINUATION	$7,343,401
2021	2021	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Treatment Research	003	8	8/13/2021	SUPPLEMENT FOR EXPANSION	$388,169
2021	2021	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Treatment Research	002	8	8/3/2021	SUPPLEMENT FOR EXPANSION	$242,583
2021	2020	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	000	7	4/12/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $7,974,153

Issue Date FY: 2020 ( Subtotal = $18,326,259 )
2020	2020	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	006	7	9/11/2020	SUPPLEMENT FOR EXPANSION	$123,705
2020	2020	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Treatment Research	005	7	9/10/2020	SUPPLEMENT FOR EXPANSION	$392,177
2020	2020	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	004	7	8/31/2020	NON-COMPETING CONTINUATION	$6,470,355
2020	2020	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	007	7	9/14/2020	SUPPLEMENT FOR EXPANSION	$118,727
2020	2020	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	003	7	8/21/2020	NON-COMPETING CONTINUATION	$11,221,295
2020	2019	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	002	6	2/27/2020	COMPETING CONTINUATION	$16,795,069
2020	2019	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	000	6	11/7/2019	COMPETING CONTINUATION	$0
2020	2018	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Treatment Research	001	5	2/27/2020	NON-COMPETING CONTINUATION	-$16,795,069
														Subtotal = $18,326,259

Issue Date FY: 2019 ( Subtotal = $20,443,862 )
2019	2019	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	000	6	8/15/2019	COMPETING CONTINUATION	$10,443,862
2019	2019	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	001	6	8/16/2019	COMPETING CONTINUATION	$0
2019	2019	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	003	6	9/24/2019	COMPETING CONTINUATION	$10,000,000
2019	2019	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Control	002	6	8/23/2019	COMPETING CONTINUATION	$0
														Subtotal = $20,443,862

Issue Date FY: 2018 ( Subtotal = $24,264,307 )
2018	2018	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Treatment Research	002	5	8/2/2018	NON-COMPETING CONTINUATION	-$32,414
2018	2018	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Treatment Research	000	5	7/31/2018	NON-COMPETING CONTINUATION	$4,067,602
2018	2018	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Treatment Research	003	5	9/13/2018	NON-COMPETING CONTINUATION	$20,229,119
2018	2017	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST STE 3000	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Treatment Research	001	4	8/1/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $24,264,307

Issue Date FY: 2017 ( Subtotal = $12,699,758 )
2017	2017	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Treatment Research	000	4	8/4/2017	NON-COMPETING CONTINUATION	$4,190,908
2017	2017	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION, INC.	1818 MARKET ST	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Treatment Research	001	4	9/19/2017	NON-COMPETING CONTINUATION	$8,508,850
														Subtotal = $12,699,758

Issue Date FY: 2016 ( Subtotal = $3,547,244 )
2016	2016	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION INC	1818 MARKET STREET	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Treatment Research	000	3	8/1/2016	NON-COMPETING CONTINUATION	$3,466,550
2016	2016	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION INC	1818 MARKET STREET	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Treatment Research	001	3	8/31/2016	NON-COMPETING CONTINUATION	$80,694
														Subtotal = $3,547,244

Issue Date FY: 2015 ( Subtotal = $4,227,002 )
2015	2015	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION INC	1818 MARKET STREET	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Treatment Research	000	2	8/26/2015	NON-COMPETING CONTINUATION	$4,151,859
2015	2015	ECOG-ACRIN MEDICAL RESEARCH FOUNDATION INC	1818 MARKET STREET	PHILADELPHIA	PA	19103	PHILADELPHIA	USA	Cancer Treatment Research	001	2	9/2/2015	NON-COMPETING CONTINUATION	$75,143
														Subtotal = $4,227,002

Grand Total All Awards = $165,790,834

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ECOG-ACRIN NCORP Research Base

Award Number: UG1CA189828

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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