Wednesday, December 4, 2024 12/4/2024

The Center for Advancing Point of Care in Heart, Lung, Blood and Sleep Diseases

Award Number: U54HL143541
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Project Summary/Abstract – Overall Core American healthcare is rapidly evolving to a state where efficiency, quality and patient satisfaction are dominant drivers. Several trends are driving fundamental changes in health care: 1) an expanding scope of virtual care and telemedicine, accelerated by the COVID-19 pandemic, has changed how patients, healthcare providers, and health systems interact; 2) a growing recognition of disparities leading to an emphasis in providing healthcare equitably for historically marginalized populations; 3) an increasing appreciation for the patient as a critical stakeholder in therapeutic decision-making, leading to an emphasis on patient-centered design; and 4) increasing access to home health to enable better diagnosis, prevention and management of health conditions, as illustrated by widespread adoption of home-testing for SARS-CoV-2. Despite this rapidly changing environment, heart (cardiovascular), lung, blood, and sleep disorders (HLBS) continue to cause significant morbidity, mortality, and cost in the US and worldwide. Combined, these diseases account for 41% of deaths in the US and lead to over $400B in direct health care expenses plus lost income to affected patients and caregivers. Thus, there are urgent unmet needs in HLBS. We will address these issues with the renewal of the Center for Advancing Point of Care Technologies (CAPCaT) in HLBS Disorders. CAPCaT is a highly successful Point-of-Care Technology Research Network (POCTRN) Center that leverages our experience running a medical product incubator, the Massachusetts Medical Device Development Center (M2D2) at the University of Massachusetts (Lowell and Worcester campuses), and our experience administering grants, running, and managing solicitations, and working 1:1 with awardees to advance their technologies toward commercialization. CAPCaT expanded upon the original vision and success of M2D2 and now has its own established track record and collaborative network to develop and optimize novel POC and home-based technologies to improve the diagnosis and management of HLBS disorders. Our objectives in achieving this goal are to continue: 1) identifying, through stakeholder engagement, the most promising POC and home-based technologies to address unmet medical needs; 2) supporting developmental plans, including pathways to adoption at the point of care or in the home; and 3) training and disseminating developing POC and home-based technologies to the different stakeholders.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2024	UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL	55 LAKE AVE N	WORCESTER	MA	01655	WORCESTER	USA	Cardiovascular Diseases Research	001	7	11/8/2024	NON-COMPETING CONTINUATION	$0
2025	2024	UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL	55 LAKE AVE N	WORCESTER	MA	01655	WORCESTER	USA	Cardiovascular Diseases Research	000	7	10/9/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $1,732,375 )
2024	2024	UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL	55 LAKE AVE N	WORCESTER	MA	01655	WORCESTER	USA	Cardiovascular Diseases Research	009	7	8/19/2024	NON-COMPETING CONTINUATION	$1,732,375
2024	2023	UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL	55 LAKE AVE N	WORCESTER	MA	01655	WORCESTER	USA	Cardiovascular Diseases Research	000	6	12/14/2023	COMPETING CONTINUATION	$0
2024	2023	UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL	55 LAKE AVE N	WORCESTER	MA	01655	WORCESTER	USA	Cardiovascular Diseases Research	005	6	2/19/2024	COMPETING CONTINUATION	$0
2024	2023	UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL	55 LAKE AVE N	WORCESTER	MA	01655	WORCESTER	USA	Cardiovascular Diseases Research	008	6	7/31/2024	COMPETING CONTINUATION	$0
2024	2023	UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL	55 LAKE AVE N	WORCESTER	MA	01655	WORCESTER	USA	Cardiovascular Diseases Research	004	6	2/7/2024	COMPETING CONTINUATION	$800,216
2024	2022	UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL	55 LAKE AVE N	WORCESTER	MA	01655	WORCESTER	USA	Cardiovascular Diseases Research	002	5	12/21/2023	SUPPLEMENT FOR EXPANSION	$0
2024	2022	UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL	55 LAKE AVE N	WORCESTER	MA	01655	WORCESTER	USA	Cardiovascular Diseases Research	003	5	2/7/2024	NON-COMPETING CONTINUATION	-$800,216
2024	2022	UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL	55 LAKE AVE N	WORCESTER	MA	01655	WORCESTER	USA	Cardiovascular Diseases Research	007	5	6/7/2024	SUPPLEMENT FOR EXPANSION	$0
2024	2020	UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL	55 LAKE AVE N	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	006	2	4/4/2024	SUPPLEMENT FOR EXPANSION	$0
2024	2020	UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL	55 LAKE AVE N	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	2	12/21/2023	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $1,732,375

Issue Date FY: 2023 ( Subtotal = $1,818,354 )
2023	2023	UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL	55 LAKE AVE N	WORCESTER	MA	01655	WORCESTER	USA	Cardiovascular Diseases Research	003	6	8/16/2023	COMPETING CONTINUATION	$1,818,354
2023	2022	UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL	55 LAKE AVE N	WORCESTER	MA	01655	WORCESTER	USA	Cardiovascular Diseases Research	001	5	6/23/2023	SUPPLEMENT FOR EXPANSION	$0
2023	2022	UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL	55 LAKE AVE N	WORCESTER	MA	01655	WORCESTER	USA	Cardiovascular Diseases Research	002	5	8/9/2023	NON-COMPETING CONTINUATION	$0
2023	2020	UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL	55 LAKE AVE N	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	2	6/22/2023	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $1,818,354

Issue Date FY: 2022 ( Subtotal = $2,801,001 )
2022	2022	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Cardiovascular Diseases Research	006	5	8/10/2022	SUPPLEMENT FOR EXPANSION	$1,246,597
2022	2022	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Cardiovascular Diseases Research	005	5	6/24/2022	NON-COMPETING CONTINUATION	$1,554,404
2022	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	003	2	4/27/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	004	2	5/6/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	2	12/3/2021	SUPPLEMENT FOR EXPANSION	$0
2022	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	002	2	3/22/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	2	10/16/2021	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $2,801,001

Issue Date FY: 2021 ( Subtotal = $1,562,533 )
2021	2021	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Cardiovascular Diseases Research	012	4	8/6/2021	NON-COMPETING CONTINUATION	$0
2021	2021	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Cardiovascular Diseases Research	009	4	7/14/2021	NON-COMPETING CONTINUATION	$1,562,533
2021	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	007	2	5/27/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Cardiovascular Diseases Research	005	3	3/1/2021	NON-COMPETING CONTINUATION	$0
2021	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	004	2	1/22/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	010	2	7/20/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	006	2	5/27/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	003	2	12/22/2020	SUPPLEMENT FOR EXPANSION	$0
2021	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	2	10/22/2020	SUPPLEMENT FOR EXPANSION	$0
2021	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	008	2	6/2/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	002	2	12/1/2020	SUPPLEMENT FOR EXPANSION	$0
2021	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	2	11/3/2020	SUPPLEMENT FOR EXPANSION	$0
2021	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	011	2	8/6/2021	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $1,562,533

Issue Date FY: 2020 ( Subtotal = $124,622,109 ) (Continued on the next page)
2020	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	011	2	7/25/2020	SUPPLEMENT FOR EXPANSION	$0
2020	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	007	2	7/17/2020	SUPPLEMENT FOR EXPANSION	$81,242,031
2020	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	006	2	7/16/2020	SUPPLEMENT FOR EXPANSION	$0
2020	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	015	2	8/4/2020	SUPPLEMENT FOR EXPANSION	$0
2020	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	008	2	7/18/2020	SUPPLEMENT FOR EXPANSION	$0
2020	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	004	2	7/8/2020	SUPPLEMENT FOR EXPANSION	$0
2020	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	2	5/28/2020	SUPPLEMENT FOR EXPANSION	$19,278,313
2020	2020	UNIVERSITY OF MASSACHUSETTS	55 LAKE AVE NORTH	WORCESTER	MA	01655	WORCESTER	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	012	2	7/28/2020	SUPPLEMENT FOR EXPANSION	$0
Grand Total All Awards = $135,752,793

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The Center for Advancing Point of Care in Heart, Lung, Blood and Sleep Diseases

Award Number: U54HL143541

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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