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 | Issue Date FY: 2024 ( Subtotal = $58,921,010 ) (Continued on the next page) |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01AI176310 | Predictive drivers of new onset, relapse, and progression of human autoimmunity in skin | 000 | 2 | NIH | 3/13/2024 | $1,123,272 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01DK136321 | EpoR & Stat5 regulation of ribosome biogenesis and protein synthesis in erythropoiesis | 000 | 2 | NIH | 2/29/2024 | $463,690 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AG075283 | Aging Microbiome, Immunosenescence, and risk of Multi-drug Resistant Organism Colonization and Infection in the Nursing Home | 000 | 2 | NIH | 11/16/2023 | $630,798 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R03AI173522 | Establishing a model of recurrent/chronic urinary tract infection in lupus-prone mice | 000 | 2 | NIH | 10/24/2023 | $75,375 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01DK133265 | Team Support to Improve Glycemic Control Using CGM in Diverse Populations (TEAM CGM) | 000 | 2 | NIH | 4/2/2024 | $634,122 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI173593 | Harnessing Age-Associated B cells for a Universal Influenza Vaccine for the Aged | 000 | 2 | NIH | 10/26/2023 | $188,438 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI173903 | Intestinal IgA B cell receptor-specific signals integrate germinal center selection with humoral responses to commensals | 000 | 2 | NIH | 10/24/2023 | $188,438 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | P50MH129701 | The Center for Accelerating Practices to End Suicide through Technology Translation (CAPES) | 001 | 2 | NIH | 3/14/2024 | $2,913,126 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31NS132424 | Modulation of Somatic Repeat Expansion as a Therapeutic Approach to Huntington's Disease | 000 | 2 | NIH | 3/15/2024 | $32,478 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI173076 | Novel histone-binding C-type lectin receptors and their role in sterile inflammation and tissue injury | 000 | 2 | NIH | 10/28/2023 | $534,478 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AR081941 | Dissecting the structural origin of relaxation in skeletal muscle | 000 | 2 | NIH | 3/11/2024 | $510,139 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31NS132495 | Investigating the Role of cnb-1 and chpf-1 in GABA DD Motor Neuron Remodeling and Synapse Maintenance | 000 | 2 | NIH | 3/28/2024 | $34,980 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI169842 | FLAVIN-CONTAINING MONO-OXYGENASES AS NOVEL INNATE IMMUNITY EFFECTORS | 000 | 2 | NIH | 1/11/2024 | $188,438 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NS126821 | Cellular and Molecular Mechanisms Underlying Neuronal Type-specific Axon Regeneration | 001 | 2 | NIH | 4/9/2024 | $29,313 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NS126821 | Cellular and Molecular Mechanisms Underlying Neuronal Type-specific Axon Regeneration | 000 | 2 | NIH | 2/12/2024 | $376,875 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01CA269711 | Targeting the detoxification function of the enzyme KDSR for cancer therapy | 000 | 2 | NIH | 11/30/2023 | $349,944 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01HL167527 | Translating post-infarct ventricular tachycardia mechanisms into a therapy | 000 | 2 | NIH | 12/20/2023 | $738,513 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01AI172987 | Development of targeted microbiome therapeutics and dietary interventions for potent intestinal barrier promotion to minimize GI-ARS | 000 | 2 | NIH | 11/14/2023 | $528,840 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AR081355 | Cellular and molecular regulators of melanocyte regeneration | 001 | 2 | NIH | 4/1/2024 | $84,712 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K01HL163254 | ActivityChoice: A clinic-delivered implementation program to increase physical activity and decrease cardiovascular disease risk amongst cancer survivors | 000 | 2 | NIH | 11/13/2023 | $162,485 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21NS131756 | Role of Sarm1 in TBI-accentuated C9orf72 Frontotemporal Dementia | 000 | 2 | NIH | 1/23/2024 | $209,375 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AR081791 | Environmental Factors Associated with the Development of Osteoarthritis | 001 | 2 | NIH | 3/13/2024 | $673,769 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31NS127555 | Establishing and Optimizing a Prime Editing Method in Neurons for Treatment of Rett Syndrome | 000 | 2 | NIH | 12/27/2023 | $32,460 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NR020439 | Structural Racism and Engagement of Family Caregivers in Serious Illness Care | 000 | 3 | NIH | 1/3/2024 | $644,368 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01GM145062 | Post-transcriptional regulation of germline mRNAs in C. elegans | 000 | 3 | NIH | 3/18/2024 | $310,546 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01CA269903 | Increasing Nodule Detection in Lung Cancer by Non-Conscious Detection of "Missed" Nodules and Machine Learning | 000 | 3 | NIH | 2/15/2024 | $179,061 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01HD104971 | Characterization of the gene regulatory network governing the first cell fate decision in mammalian embryonic development | 000 | 3 | NIH | 3/14/2024 | $464,308 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01AI165524 | A systems immunology approach to evaluate malaria vaccine performance in endemic regions of Kenya | 000 | 3 | NIH | 1/26/2024 | $888,892 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01AI168640 | Parsing cholesterol metabolite regulation of skin immunocytes in children to identify archetypes of human neonatal immune system | 000 | 3 | NIH | 2/15/2024 | $735,209 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31NS124338 | Investigating Mechanisms of Neurodegeneration | 000 | 3 | NIH | 4/3/2024 | $19,053 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U24HG012343 | A Comprehensive Genomic Community Resource of Transcriptional Regulation | 000 | 3 | NIH | 3/27/2024 | $903,892 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM145263 | Transgenerational epigenetic regulation by Rlim | 000 | 3 | NIH | 2/19/2024 | $376,875 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI158832 | Cholesterol metabolites coordinate skin barrier immunity centered on innate dermal gammadelta T cells programmed to produce IL-17 | 000 | 3 | NIH | 10/30/2023 | $637,049 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AR078230 | Novel approaches to promote healing of bone loss in inflammatory arthritis | 000 | 3 | NIH | 2/23/2024 | $472,761 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31NS122493 | The Impact of Nucleotide Modification Patterns on Therapeutic Small Interfering RNA Activity in the Central Nervous System | 000 | 3 | NIH | 12/20/2023 | $25,662 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01DK126804 | Extracellular protease modulation of the cilium transition zone in kidney development and disease | 000 | 3 | NIH | 12/18/2023 | $331,650 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K23NS126718 | MRI Paramagnetic Rim Lesions as Biomarkers and Agents of Neurodegeneration in Multiple Sclerosis | 000 | 3 | NIH | 4/2/2024 | $221,553 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01CA258712 | Targeting MTOR signaling in pancreatic cancer | 000 | 3 | NIH | 3/26/2024 | $527,183 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | T32HL171799 | CardiOvascular Digital hEalth Research (CODER) Training Program | 000 | 1 | NIH | 12/27/2023 | $186,572 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI175883 | What Precursors Become Lung-Resident CD4 Memory that Protect Against Respiratory Infections or Cause Lung Pathology? | 001 | 1 | NIH | 3/7/2024 | $0 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI175883 | What Precursors Become Lung-Resident CD4 Memory that Protect Against Respiratory Infections or Cause Lung Pathology? | 000 | 1 | NIH | 11/21/2023 | $226,125 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F30AI181515 | Characterization of Enterovirus 68 3C Protease For the Development of Robust and Potent Direct-Acting Antiviral Inhibitors | 001 | 1 | NIH | 12/15/2023 | $0 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F30AI181515 | Characterization of Enterovirus 68 3C Protease For the Development of Robust and Potent Direct-Acting Antiviral Inhibitors | 000 | 1 | NIH | 12/15/2023 | $52,694 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K99CA281094 | Identifying and examining the effects of source and presentation on responses to electronic cigarette public education messages in young adult vapers and non-vapers | 001 | 1 | NIH | 1/9/2024 | $0 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI184042 | Ectodomain shedding and HIV replication | 000 | 1 | NIH | 2/5/2024 | $662,784 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI184042 | Ectodomain shedding and HIV replication | 001 | 1 | NIH | 2/15/2024 | $0 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F30DA058525 | Implementation of Medications for Opioid Use Disorder in Massachusetts Jails | 000 | 1 | NIH | 12/27/2023 | $35,089 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K99CA281094 | Identifying and examining the effects of source and presentation on responses to electronic cigarette public education messages in young adult vapers and non-vapers | 000 | 1 | NIH | 12/28/2023 | $151,913 |
| | 2024 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F32AI176649 | Glutamine Starvation as a Means to Enhance Antibiotic Efficacy against M. tuberculosis | 000 | 1 | NIH | 4/1/2024 | $69,500 |
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