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 | Issue Date FY: 2025 ( Subtotal = $21,730,763 ) (Continued on the next page) |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K23HL163450 | Development of a Mobile Health Intervention for Blood Pressure Management in Pregnancy | 000 | 2 | NIH | 1/13/2025 | $190,058 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31GM157877 | Engineering bacterial group I introns for efficient production of safe and durable nucleoside-modified circular mRNA therapeutics | 000 | 1 | NIH | 11/25/2024 | $33,780 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31GM157877 | Engineering bacterial group I introns for efficient production of safe and durable nucleoside-modified circular mRNA therapeutics | 001 | 1 | NIH | 11/25/2024 | $0 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | T32HL171799 | CardiOvascular Digital hEalth Research (CODER) Training Program | 000 | 2 | NIH | 11/22/2024 | $303,286 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F30DA058525 | Implementation of Medications for Opioid Use Disorder in Massachusetts Jails | 000 | 2 | NIH | 11/25/2024 | $32,974 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31AI189160 | Temporal Regulation of mRNA Biogenesis in Immune Responses | 000 | 1 | NIH | 11/19/2024 | $33,806 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM122597 | RNA and Genomic Junk in Fundamental Chromosome Architecture and Regulation | 001 | 8 | NIH | 1/15/2025 | $558,790 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI180971 | Reprogramming of the innate immunometabolism by bacterial biofilms | 000 | 2 | NIH | 11/6/2024 | $200,475 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI173076 | Novel histone-binding C-type lectin receptors and their role in sterile inflammation and tissue injury | 000 | 3 | NIH | 11/6/2024 | $576,048 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AG075283 | Aging Microbiome, Immunosenescence, and risk of Multi-drug Resistant Organism Colonization and Infection in the Nursing Home | 000 | 3 | NIH | 12/3/2024 | $631,844 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F30AI181515 | Characterization of Enterovirus 68 3C Protease For the Development of Robust and Potent Direct-Acting Antiviral Inhibitors | 000 | 2 | NIH | 11/29/2024 | $53,974 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01AI172987 | Development of targeted microbiome therapeutics and dietary interventions for potent intestinal barrier promotion to minimize GI-ARS | 000 | 3 | NIH | 12/5/2024 | $568,565 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI184042 | Ectodomain shedding and HIV replication | 000 | 2 | NIH | 12/6/2024 | $714,334 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI182355 | Combining B. thuringiensis crystal proteins with small molecule anthelmintics to combat parasitic nematode resistance | 000 | 1 | NIH | 12/16/2024 | $769,201 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01HL167527 | Translating post-infarct ventricular tachycardia mechanisms into a therapy | 000 | 3 | NIH | 12/13/2024 | $728,330 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K23HD112602 | Promoting community-based Kangaroo Care among mothers of low birth weight infants in rural India | 000 | 1 | NIH | 12/26/2024 | $163,003 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K08AI180429 | The Role of ADAM9 in the Innate Immune Response to SARS-CoV-2 Infection | 000 | 1 | NIH | 12/26/2024 | $190,058 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31NS127555 | Establishing and Optimizing a Prime Editing Method in Neurons for Treatment of Rett Syndrome | 000 | 3 | NIH | 12/20/2024 | $33,740 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | UG3DK142192 | Models to study the synergy between autoimmunity and metabolism in T1D | 000 | 1 | NIH | 12/23/2024 | $1,208,620 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM156361 | Structural mechanisms of multimeric ATPases | 000 | 1 | NIH | 12/24/2024 | $669,281 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F30DK127690 | Detection of intestinal pathogens through host surveillance of bacterial toxins | 000 | 5 | NIH | 1/14/2025 | $24,593 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R03AI190223 | Molecular and metabolic characterization of gut stromal cells underpinning efficient intestinal B cell response | 000 | 1 | NIH | 1/10/2025 | $81,238 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AG068670 | Dual transcriptional programs coordinate lipogenic and membrane stress responsive programs in C. elegans | 000 | 5 | NIH | 1/10/2025 | $387,463 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01CA269903 | Increasing Nodule Detection in Lung Cancer by Non-Conscious Detection of "Missed" Nodules and Machine Learning | 000 | 4 | NIH | 1/8/2025 | $509,294 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01CA269711 | Targeting the detoxification function of the enzyme KDSR for cancer therapy | 000 | 3 | NIH | 1/8/2025 | $348,322 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AR081791 | Environmental Factors Associated with the Development of Osteoarthritis | 000 | 3 | NIH | 1/16/2025 | $355,567 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | P40OD028116 | Nonhuman Primate Antibody Resource for Immune Cell Depletion | 000 | 6 | NIH | 1/13/2025 | $496,815 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM131741 | Genetic control of developmental timing | 002 | 6 | NIH | 1/15/2025 | $844,267 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI060025 | From Drosophila Immunity to Anti-Inflammatories | 000 | 21 | NIH | 11/4/2024 | $592,836 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI175987 | The impact of IL-4 and IL-4-producing cells on protective immunity to tuberculosis | 000 | 2 | NIH | 10/31/2024 | $213,412 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI158832 | Cholesterol metabolites coordinate skin barrier immunity centered on innate dermal gammadelta T cells programmed to produce IL-17 | 000 | 4 | NIH | 10/30/2024 | $686,599 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F30AI188981 | The role of caspase-3 mediated cleavage of VPS4A in restricting HSV-1 | 000 | 1 | NIH | 11/5/2024 | $36,459 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI187460 | Generation & Regulation of Tfh13 cells that drive Pathogenic IgE in Allergy | 000 | 1 | NIH | 11/12/2024 | $586,250 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI182052 | Regulation of the NLRP1 inflammasome by HSV-1 | 000 | 1 | NIH | 11/12/2024 | $658,273 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R00MD017269 | Effects of Early and Prolonged Parent-Child Separation: Understanding Mental Health among Separated-Reunited Chinese American Children | 000 | 4 | NIH | 11/11/2024 | $224,023 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K01HL163254 | ActivityChoice: A clinic-delivered implementation program to increase physical activity and decrease cardiovascular disease risk amongst cancer survivors | 000 | 3 | NIH | 11/11/2024 | $162,485 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NS064263 | Molecular Analysis of Neural Circuit Excitation and Inhibition | 000 | 14 | NIH | 11/15/2024 | $399,690 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI183080 | In vitro and in vivo modeling of gene therapy vector stability when challenged by natural virus infection in human hepatocytes | 000 | 1 | NIH | 11/13/2024 | $284,331 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K99NS136849 | Advanced Base and Prime Editing Strategies to Correct Common ALS-causing SOD1 Mutations | 000 | 1 | NIH | 11/19/2024 | $124,246 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R13HD117638 | Diversifying the Autism Research Workforce Conference | 001 | 1 | NIH | 1/8/2025 | $10,000 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R13HD117638 | Diversifying the Autism Research Workforce Conference | 000 | 1 | NIH | 12/30/2024 | $10,000 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01GM060992 | Intraflagellar Transport Proteins in Mice | 000 | 24 | NIH | 1/16/2025 | $408,137 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35HL171534 | Developmental origins of pericyte heterogeneity | 000 | 2 | NIH | 1/3/2025 | $1,055,250 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NS126821 | Cellular and Molecular Mechanisms Underlying Neuronal Type-specific Axon Regeneration | 000 | 3 | NIH | 1/16/2025 | $376,875 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01DK126804 | Extracellular protease modulation of the cilium transition zone in kidney development and disease | 000 | 4 | NIH | 12/23/2024 | $331,650 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K99CA281094 | Identifying and examining the effects of source and presentation on responses to electronic cigarette public education messages in young adult vapers and non-vapers | 000 | 2 | NIH | 1/15/2025 | $137,562 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM133762 | Tracking transcriptome diversity in real-time | 002 | 6 | NIH | 1/6/2025 | $479,050 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01DA042475 | Noradrenergic Regulation in the BNST | 001 | 9 | NIH | 12/3/2024 | $308,214 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM145261 | Investigating the molecules and mechanisms of bacterial cell-cell interactions | 000 | 3 | NIH | 11/8/2024 | $0 |
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