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 | Issue Date FY: 2023 ( Subtotal = $111,183,722 ) (Continued on the next page) |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31NS122493 | The Impact of Nucleotide Modification Patterns on Therapeutic Small Interfering RNA Activity in the Central Nervous System | 000 | 2 | NIH | 1/4/2023 | $31,506 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01GM145062 | Post-transcriptional regulation of germline mRNAs in C. elegans | 000 | 2 | NIH | 3/16/2023 | $345,050 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21NR020231 | Improving patient care in severe acute brain injury: a web/mobile/tablet-based communication and decision support tool for clinicians and families in the neuro-ICU | 001 | 2 | NIH | 2/9/2023 | $20,556 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AR078230 | Novel approaches to promote healing of bone loss in inflammatory arthritis | 001 | 2 | NIH | 2/24/2023 | $52,443 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31NS132424 | Modulation of Somatic Repeat Expansion as a Therapeutic Approach to Huntington's Disease | 001 | 1 | NIH | 3/20/2023 | $0 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI172204 | Development of nucleic acid-based vaccines against gonorrhea | 000 | 2 | NIH | 3/28/2023 | $209,375 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM145261 | Investigating the molecules and mechanisms of bacterial cell-cell interactions | 000 | 1 | NIH | 5/23/2023 | $54,261 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01CE003514 | Supporting Treatment Access and Recovery through Linkage and Support (STAR-LS) | 00 | 2 | CDC | 4/17/2023 | $749,446 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21NR020231 | Improving patient care in severe acute brain injury: a web/mobile/tablet-based communication and decision support tool for clinicians and families in the neuro-ICU | 000 | 2 | NIH | 12/12/2022 | $185,006 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AR078230 | Novel approaches to promote healing of bone loss in inflammatory arthritis | 000 | 2 | NIH | 2/10/2023 | $471,993 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31NS132424 | Modulation of Somatic Repeat Expansion as a Therapeutic Approach to Huntington's Disease | 000 | 1 | NIH | 3/20/2023 | $32,478 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01CE003514 | Supporting Treatment Access and Recovery through Linkage and Support (STAR-LS) | 01 | 2 | CDC | 5/9/2023 | $0 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01HL164560 | Structural basis of the super-relaxed state in human cardiac muscle | 000 | 2 | NIH | 6/2/2023 | $704,500 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21ES031802 | Impact of circadian disruption on pancreatic cancer development and progression | 000 | 2 | NIH | 11/10/2022 | $251,250 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS | 55 LAKE AVE NORTH | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI158832 | Cholesterol metabolites coordinate skin barrier immunity centered on innate dermal gammadelta T cells programmed to produce IL-17 | 000 | 2 | NIH | 10/31/2022 | $707,833 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31DK129018 | Elucidating the role of hepatic mTORC2 as a key regulator of carbohydrate metabolism in non-alcoholic fatty liver disease | 000 | 2 | NIH | 12/8/2022 | $33,958 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | P50MH129701 | The Center for Accelerating Practices to End Suicide through Technology Translation (CAPES) | 000 | 1 | NIH | 4/5/2023 | $3,360,660 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31DK129018 | Elucidating the role of hepatic mTORC2 as a key regulator of carbohydrate metabolism in non-alcoholic fatty liver disease | 001 | 2 | NIH | 2/17/2023 | $942 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31CA268847 | Activation of non-apoptotic cell death by the DNA damage response | 000 | 2 | NIH | 12/22/2022 | $31,506 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F32DA053797 | Involvement of habenulo-interpeduncular circuitry in nicotine reward and aversion | 000 | 2 | NIH | 2/7/2023 | $73,772 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01HG012064 | Predictive Modeling of the Functional and Phenotypic Impacts of Genetic Variants | 000 | 3 | NIH | 5/24/2023 | $752,388 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AG073238 | Effects of paternal aging on male reproductive biology and on future generations | 000 | 3 | NIH | 4/19/2023 | $508,917 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01DK127175 | Quantitative and functional analysis of brown fat nutrient fluxes in vivo and its role in organ metabolite exchange | 000 | 3 | NIH | 5/23/2023 | $543,007 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | UT441898 | MCH Research Network on Promoting Healthy Weight (HW-RN) among Children with ASD and other DD | 00 | 3 | HRSA | 5/12/2023 | $250,000 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AG071692 | Social Connectedness and Social Isolation in Nursing Home Residents | 000 | 3 | NIH | 3/20/2023 | $808,834 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI173593 | Harnessing Age-Associated B cells for a Universal Influenza Vaccine for the Aged | 001 | 1 | NIH | 5/15/2023 | -$251,250 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NS132935 | Therapeutic Potential of Rescued FMR1 Mis-Splicing in Fragile X Syndrome | 000 | 1 | NIH | 5/23/2023 | $418,750 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01AI176310 | Predictive drivers of new onset, relapse, and progression of human autoimmunity in skin | 000 | 1 | NIH | 4/20/2023 | $1,264,957 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R25DA058490 | The ANTIDOTE Institute- Advancing New Toxicology Investigators in Drug abuse and Original Translational research Efforts | 000 | 1 | NIH | 4/19/2023 | $301,993 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM148225 | Dissecting the Molecular Mechanisms of Exocytic Vesicle Tethering and Fusion | 000 | 1 | NIH | 5/26/2023 | $669,060 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AG071692 | Social Connectedness and Social Isolation in Nursing Home Residents | 001 | 3 | NIH | 6/2/2023 | $0 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R37AI155901 | The role of TLRs, Type II IFN and Type III IFN in a Murine Model of Autoinflammation | 000 | 3 | NIH | 1/31/2023 | $494,929 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI159182 | Structure-guided and epitope-based design of potent and broadly neutralizing nanobodies for COVID-19 mucosal immunotherapy | 000 | 3 | NIH | 5/26/2023 | $694,551 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI155727 | Diet-derived oxysterols shape intestinal B cell fate by controlling intracellular cholesterol metabolism | 000 | 3 | NIH | 6/2/2023 | $467,227 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01CA255319 | Leveraging canine spontaneous cancer to optimize the power of blood biopsy | 000 | 3 | NIH | 6/1/2023 | $573,297 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31NS132495 | Investigating the Role of cnb-1 and chpf-1 in GABA DD Motor Neuron Remodeling and Synapse Maintenance | 002 | 1 | NIH | 3/10/2023 | $0 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31NS132495 | Investigating the Role of cnb-1 and chpf-1 in GABA DD Motor Neuron Remodeling and Synapse Maintenance | 001 | 1 | NIH | 3/10/2023 | $0 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AR081355 | Cellular and molecular regulators of melanocyte regeneration | 000 | 1 | NIH | 3/31/2023 | $355,520 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01DK136013 | Mechanical regulation of intestine stem cell-mediated tissue homeostasis in Drosophila | 000 | 1 | NIH | 3/28/2023 | $368,500 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K01DK131318 | DM-BOOST para Latinx: a Diabetes Mellitus program using Behavioral economics to Optimize Outreach and Self-management support with Technology for Latinx patients | 000 | 2 | NIH | 4/4/2023 | $163,644 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM146824 | Spatial and temporal regulation of nutrient sensing | 000 | 2 | NIH | 5/10/2023 | $418,750 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21MH129040 | A role for the interpeduncular nucleus in innate defensive behaviors | 000 | 2 | NIH | 1/17/2023 | $209,375 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI171474 | Embryonic type 3 innate lymphoid cells sense maternal dietary cholesterol to shape mucosal lymphoid organ development | 000 | 2 | NIH | 5/11/2023 | $209,375 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31AR082678 | Muscle-Specific CRISPR/Cas9 Exon Skipping for Duchenne Muscular Dystrophy Therapeutics | 000 | 1 | NIH | 3/9/2023 | $32,478 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01AI172987 | Development of targeted microbiome therapeutics and dietary interventions for potent intestinal barrier promotion to minimize GI-ARS | 000 | 1 | NIH | 12/22/2022 | $601,576 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01HL167527 | Translating post-infarct ventricular tachycardia mechanisms into a therapy | 000 | 1 | NIH | 1/9/2023 | $823,836 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01HD104971 | Characterization of the gene regulatory network governing the first cell fate decision in mammalian embryonic development | 000 | 2 | NIH | 3/8/2023 | $515,898 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI170722 | Mechanisms underlying bacterial sensitivity to host-targeted drugs | 000 | 2 | NIH | 5/2/2023 | $534,489 |
| | 2023 | 2023 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U24HG012343 | A Comprehensive Genomic Community Resource of Transcriptional Regulation | 000 | 2 | NIH | 3/17/2023 | $809,378 |
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