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 | Issue Date FY: 2025 ( Subtotal = $7,382,044 ) (Continued on the next page) |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI180971 | Reprogramming of the innate immunometabolism by bacterial biofilms | 000 | 2 | NIH | 11/6/2024 | $200,475 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI175987 | The impact of IL-4 and IL-4-producing cells on protective immunity to tuberculosis | 000 | 2 | NIH | 10/31/2024 | $213,412 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI187460 | Generation & Regulation of Tfh13 cells that drive Pathogenic IgE in Allergy | 000 | 1 | NIH | 11/12/2024 | $586,250 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K01HL163254 | ActivityChoice: A clinic-delivered implementation program to increase physical activity and decrease cardiovascular disease risk amongst cancer survivors | 000 | 3 | NIH | 11/11/2024 | $162,485 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI182052 | Regulation of the NLRP1 inflammasome by HSV-1 | 000 | 1 | NIH | 11/12/2024 | $658,273 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R00MD017269 | Effects of Early and Prolonged Parent-Child Separation: Understanding Mental Health among Separated-Reunited Chinese American Children | 000 | 4 | NIH | 11/11/2024 | $224,023 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI060025 | From Drosophila Immunity to Anti-Inflammatories | 000 | 21 | NIH | 11/4/2024 | $592,836 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F30AI188981 | The role of caspase-3 mediated cleavage of VPS4A in restricting HSV-1 | 000 | 1 | NIH | 11/5/2024 | $36,459 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F30AI181515 | Characterization of Enterovirus 68 3C Protease For the Development of Robust and Potent Direct-Acting Antiviral Inhibitors | 000 | 2 | NIH | 11/29/2024 | $53,974 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F30DA058525 | Implementation of Medications for Opioid Use Disorder in Massachusetts Jails | 000 | 2 | NIH | 11/25/2024 | $32,974 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31GM157877 | Engineering bacterial group I introns for efficient production of safe and durable nucleoside-modified circular mRNA therapeutics | 000 | 1 | NIH | 11/25/2024 | $33,780 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | T32HL171799 | CardiOvascular Digital hEalth Research (CODER) Training Program | 000 | 2 | NIH | 11/22/2024 | $303,286 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K99NS136849 | Advanced Base and Prime Editing Strategies to Correct Common ALS-causing SOD1 Mutations | 000 | 1 | NIH | 11/19/2024 | $124,246 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31AI189160 | Temporal Regulation of mRNA Biogenesis in Immune Responses | 000 | 1 | NIH | 11/19/2024 | $33,806 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI183080 | In vitro and in vivo modeling of gene therapy vector stability when challenged by natural virus infection in human hepatocytes | 000 | 1 | NIH | 11/13/2024 | $284,331 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI173076 | Novel histone-binding C-type lectin receptors and their role in sterile inflammation and tissue injury | 000 | 3 | NIH | 11/6/2024 | $576,048 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI158832 | Cholesterol metabolites coordinate skin barrier immunity centered on innate dermal gammadelta T cells programmed to produce IL-17 | 000 | 4 | NIH | 10/30/2024 | $686,599 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NS064263 | Molecular Analysis of Neural Circuit Excitation and Inhibition | 000 | 14 | NIH | 11/15/2024 | $399,690 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM152201 | Cell Biology of Mammalian Nuclei | 000 | 1 | NIH | 11/11/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | UG3NS132136 | varCUT&Tag: A Method for Simultaneous Identification and Characterization of Sequence Variants in Regulatory Elements and Genes | 000 | 2 | NIH | 11/4/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AG071692 | Social Connectedness and Social Isolation in Nursing Home Residents | 000 | 4 | NIH | 10/29/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM148277 | Translation, targeting, and decay of yeast nonsense-containing mRNAs | 000 | 2 | NIH | 11/5/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM151996 | Defining and Avoiding Molecular Mechanisms of Drug Resistance | 000 | 1 | NIH | 11/6/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM148225 | Dissecting the Molecular Mechanisms of Exocytic Vesicle Tethering and Fusion | 000 | 2 | NIH | 11/6/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM136280 | Molecular Mechanisms of Cell Cycle Control | 000 | 5 | NIH | 11/7/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM149284 | Mechanisms of the gut-brain axis that regulate innate immunity | 000 | 2 | NIH | 11/5/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM148359 | Regulation of Key Cell Cycle Events | 000 | 2 | NIH | 11/5/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM136275 | Understanding the Evolution, Biology, and Molecular Mechanism of Argonaute Proteins | 000 | 5 | NIH | 11/4/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM152194 | Systems and Network-level Regulation of Cell Death | 000 | 1 | NIH | 11/4/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R34MH134682 | Optimizing mobile interventions to overcome stigma and promote HIV prevention among Thai young transgender women | 000 | 1 | NIH | 10/19/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R00HD109359 | First murine animal model and adeno-associated virus (AAV)-based gene therapy for MTATP6 mitochondrial diseases | 000 | 3 | NIH | 10/21/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U54HL143541 | The Center for Advancing Point of Care in Heart, Lung, Blood and Sleep Diseases | 001 | 7 | NIH | 11/8/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U54HL143541 | The Center for Advancing Point of Care in Heart, Lung, Blood and Sleep Diseases | 000 | 7 | NIH | 10/9/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | H79TI086409 | Supporting Treatment Access and Recovery for Homelessness (STAR-H) | 000 | 1 | SAMHSA | 10/23/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | C06OD037781 | A Biosafety Level 3 Laboratory for Viral Pathogens | 001 | 1 | NIH | 10/30/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | C06OD037781 | A Biosafety Level 3 Laboratory for Viral Pathogens | 000 | 1 | NIH | 10/17/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31DK129018 | Elucidating the role of hepatic mTORC2 as a key regulator of carbohydrate metabolism in non-alcoholic fatty liver disease | 000 | 3 | NIH | 10/23/2024 | -$19,309 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | TR753199 | Regional AIDS Education and Training Centers Program | 04 | 1 | HRSA | 11/12/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | TR753199 | Regional AIDS Education and Training Centers Program | 04 | 1 | HRSA | 11/12/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | TR753199 | Regional AIDS Education and Training Centers Program | 04 | 1 | HRSA | 11/12/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | TR753199 | Regional AIDS Education and Training Centers Program | 03 | 1 | HRSA | 10/4/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | TR753199 | Regional AIDS Education and Training Centers Program | 03 | 1 | HRSA | 10/4/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | TR753199 | Regional AIDS Education and Training Centers Program | 03 | 1 | HRSA | 10/4/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U48DP006808 | DP24-004, PRC, Core: Prevention Research Center at UMass Chan | 01 | 1 | CDC | 11/22/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U48DP006883 | ARISe Center for Rural Vaccination at University of Massachusetts Chan Medical School | 01 | 1 | CDC | 10/25/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01CE003514 | RFA-CE-22-010, Supporting Treatment Access and Recovery through Linkage and Support (STAR-LS) | 01 | 3 | CDC | 10/29/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM122502 | Gene regulatory and metabolic network structure, function and evolution | 000 | 8 | NIH | 11/8/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM118112 | Chemical probes to decipher PAD biology | 000 | 9 | NIH | 11/18/2024 | $0 |
| | 2025 | 2024 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM118330 | Mechanisms and consequences of programmed cell death (apoptosis) and compensatory proliferation in Drosophila | 000 | 9 | NIH | 11/29/2024 | $0 |
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