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 | Issue Date FY: 2025 ( Subtotal = $45,706,400 ) (Continued on the next page) |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35HL171534 | Developmental origins of pericyte heterogeneity | 000 | 2 | NIH | 1/3/2025 | $1,055,250 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AG075283 | Aging Microbiome, Immunosenescence, and risk of Multi-drug Resistant Organism Colonization and Infection in the Nursing Home | 000 | 3 | NIH | 12/3/2024 | $631,844 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01MD018611 | Motivational Interviewing Training to Promote COVID-19 and Influenza Vaccination (MI-VAX): What Providers Need and Patients Want | 000 | 2 | NIH | 1/18/2025 | $640,814 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R13HD117638 | Diversifying the Autism Research Workforce Conference | 000 | 1 | NIH | 12/30/2024 | $10,000 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F32NS134683 | A comparative analysis of OPC and microglia phagocytosis and its relevance to neurodegenerative disease | 000 | 1 | NIH | 1/24/2025 | $3,000 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01AI165524 | A systems immunology approach to evaluate malaria vaccine performance in endemic regions of Kenya | 000 | 4 | NIH | 2/13/2025 | $958,026 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01DK107603 | Mucosal Macrophages and Tertiary Lymphoid Structures in IBD | 000 | 10 | NIH | 2/20/2025 | $492,283 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01DK136321 | EpoR & Stat5 regulation of ribosome biogenesis and protein synthesis in erythropoiesis | 000 | 3 | NIH | 3/14/2025 | $463,690 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AA028240 | A Female-Specific Cognitive Behavioral Therapy Group for Alcohol Use Disorder in VA Primary Care Settings | 000 | 5 | NIH | 2/27/2025 | $581,852 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K22CA288784 | Deciphering the Immune Evasion Mechanisms in Mutant IDH1 Cancer | 000 | 1 | NIH | 3/18/2025 | $196,029 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K23NS126718 | MRI Paramagnetic Rim Lesions as Biomarkers and Agents of Neurodegeneration in Multiple Sclerosis | 000 | 4 | NIH | 3/19/2025 | $221,553 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31NS127555 | Establishing and Optimizing a Prime Editing Method in Neurons for Treatment of Rett Syndrome | 001 | 3 | NIH | 3/20/2025 | -$26,734 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21NS139100 | Investigating Dysfunction of Neuroimmune-Related Processes in Models of ALS/FTD TDP-43 | 000 | 1 | NIH | 3/20/2025 | $251,250 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31AI189160 | Temporal Regulation of mRNA Biogenesis in Immune Responses | 001 | 1 | NIH | 11/19/2024 | $0 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31NS132424 | Modulation of Somatic Repeat Expansion as a Therapeutic Approach to Huntington's Disease | 000 | 3 | NIH | 3/28/2025 | $33,758 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | UH3DE030070 | MAP for Child Health: Using Social Networks to Improve child health and oral health | 000 | 5 | NIH | 3/20/2025 | $927,273 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | UH3DE030070 | MAP for Child Health: Using Social Networks to Improve child health and oral health | 000 | 5 | NIH | 3/20/2025 | $200,000 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AG086903 | Metabolomic interrogation of gut mechanosensing in Drosophila | 000 | 2 | NIH | 3/19/2025 | $183,094 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NS104022 | Expanding the Chemical Diversity of Therapeutic Oligonucleotides | 000 | 8 | NIH | 3/20/2025 | $619,376 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI182982 | Regulation of Ninj1 oligomerization and cell membrane ruptures during cell death | 000 | 2 | NIH | 2/12/2025 | $203,094 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01AI168640 | Parsing cholesterol metabolite regulation of skin immunocytes in children to identify archetypes of human neonatal immune system | 000 | 4 | NIH | 2/12/2025 | $792,392 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R37AI155901 | The role of TLRs, Type II IFN and Type III IFN in a Murine Model of Autoinflammation | 000 | 5 | NIH | 2/12/2025 | $494,929 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI183080 | In vitro and in vivo modeling of gene therapy vector stability when challenged by natural virus infection in human hepatocytes | 000 | 1 | NIH | 11/13/2024 | $284,331 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R13HD117638 | Diversifying the Autism Research Workforce Conference | 001 | 1 | NIH | 1/8/2025 | $10,000 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01CA269903 | Increasing Nodule Detection in Lung Cancer by Non-Conscious Detection of "Missed" Nodules and Machine Learning | 000 | 4 | NIH | 1/8/2025 | $509,294 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01CA269711 | Targeting the detoxification function of the enzyme KDSR for cancer therapy | 000 | 3 | NIH | 1/8/2025 | $348,322 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | UG3DK142192 | Models to study the synergy between autoimmunity and metabolism in T1D | 000 | 1 | NIH | 12/23/2024 | $1,208,620 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM133762 | Tracking transcriptome diversity in real-time | 002 | 6 | NIH | 1/6/2025 | $479,050 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AR081791 | Environmental Factors Associated with the Development of Osteoarthritis | 000 | 3 | NIH | 1/16/2025 | $355,567 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AG068670 | Dual transcriptional programs coordinate lipogenic and membrane stress responsive programs in C. elegans | 000 | 5 | NIH | 1/10/2025 | $387,463 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R03AI190223 | Molecular and metabolic characterization of gut stromal cells underpinning efficient intestinal B cell response | 000 | 1 | NIH | 1/10/2025 | $81,238 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K99CA281094 | Identifying and examining the effects of source and presentation on responses to electronic cigarette public education messages in young adult vapers and non-vapers | 000 | 2 | NIH | 1/15/2025 | $137,562 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01GM060992 | Intraflagellar Transport Proteins in Mice | 000 | 24 | NIH | 1/16/2025 | $408,137 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI191052 | Comprehensive analysis of epistasis in drug resistance potential of Mpro from SARS-CoV-2 | 000 | 1 | NIH | 2/1/2025 | $243,713 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM131741 | Genetic control of developmental timing | 002 | 6 | NIH | 1/15/2025 | $844,267 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM156361 | Structural mechanisms of multimeric ATPases | 000 | 1 | NIH | 12/24/2024 | $669,281 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NS126821 | Cellular and Molecular Mechanisms Underlying Neuronal Type-specific Axon Regeneration | 000 | 3 | NIH | 1/16/2025 | $376,875 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F30AI181515 | Characterization of Enterovirus 68 3C Protease For the Development of Robust and Potent Direct-Acting Antiviral Inhibitors | 000 | 2 | NIH | 11/29/2024 | $53,974 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01DK126804 | Extracellular protease modulation of the cilium transition zone in kidney development and disease | 000 | 4 | NIH | 12/23/2024 | $331,650 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM122597 | RNA and Genomic Junk in Fundamental Chromosome Architecture and Regulation | 001 | 8 | NIH | 1/15/2025 | $558,790 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI184042 | Ectodomain shedding and HIV replication | 000 | 2 | NIH | 12/6/2024 | $714,334 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | P40OD028116 | Nonhuman Primate Antibody Resource for Immune Cell Depletion | 000 | 6 | NIH | 1/13/2025 | $496,815 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31GM157877 | Engineering bacterial group I introns for efficient production of safe and durable nucleoside-modified circular mRNA therapeutics | 000 | 1 | NIH | 11/25/2024 | $33,780 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AR081355 | Cellular and molecular regulators of melanocyte regeneration | 000 | 3 | NIH | 3/24/2025 | $388,205 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NS101986 | Understanding Frontotemporal Dementia Using Drosophila and iPSC Models | 000 | 7 | NIH | 3/24/2025 | $625,941 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI159314 | Altered T Cell Responses in Myalgic Enchephalomeylitis/Chronic Fatigue Syndrome (ME/CFS) | 000 | 5 | NIH | 2/14/2025 | $474,267 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R37CA282805 | Uncovering the heterogenous role of senescence in prostate immune suppression and tumorigenesis | 000 | 2 | NIH | 3/7/2025 | $344,841 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01GM145062 | Post-transcriptional regulation of germline mRNAs in C. elegans | 000 | 4 | NIH | 3/25/2025 | $310,546 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NR020439 | Structural Racism and Engagement of Family Caregivers in Serious Illness Care | 000 | 4 | NIH | 2/14/2025 | $631,908 |
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