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 | Issue Date FY: 2025 ( Subtotal = $214,714,109 ) (Continued on the next page) |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01CA294209 | Integrative Analysis and Visualization Platform for Cancer Regulatory Genomics | 000 | 2 | NIH | 7/8/2025 | $414,820 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U24MH136793 | PsychENCODE Data Analysis and Coordination Center | 001 | 2 | NIH | 8/6/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U24MH136793 | PsychENCODE Data Analysis and Coordination Center | 000 | 2 | NIH | 5/14/2025 | $831,440 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NS139268 | AAV Gene Therapy for Sialidosis: from Mice to IND | 000 | 2 | NIH | 5/28/2025 | $654,844 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI181309 | RNA splicing factor Raver1 controls cell death, inflammation, and innateimmunity | 000 | 2 | NIH | 5/29/2025 | $835,485 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01DA059640 | Craving-based Digital Phenotyping During MOUD Treatment | 001 | 2 | NIH | 6/23/2025 | $821,462 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI180971 | Reprogramming of the innate immunometabolism by bacterial biofilms | 000 | 2 | NIH | 11/6/2024 | $200,475 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01DK138198 | Influence of MHC-II polymorphisms on autoimmune T cell repertoire development and function | 000 | 2 | NIH | 6/9/2025 | $530,890 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K22CA282268 | New Proteomics Approaches to Study the Full Human Kinome, Inhibitor Resistance, and Kinase Degraders | 000 | 2 | NIH | 6/3/2025 | $211,918 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31AI191745 | Investigating a hemagglutinin mediated molecular mechanism of avian influenza A virus host tropism | 001 | 1 | NIH | 6/18/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31AI191745 | Investigating a hemagglutinin mediated molecular mechanism of avian influenza A virus host tropism | 000 | 1 | NIH | 6/18/2025 | $49,538 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01DK144534 | Investigating novel mitochondrial mechanisms of obesity pathogenesis | 000 | 1 | NIH | 8/20/2025 | $2,638,760 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R56AG091682 | Medication self-administration (MSA) and awareness of MSA: life-relevant markers of cognitive impairment | 000 | 1 | NIH | 9/25/2025 | $643,089 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | H79TI088149 | Addiction Technology Transfer Center of New England | 001 | 2 | SAMHSA | 9/22/2025 | $777,850 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01AI165524 | A systems immunology approach to evaluate malaria vaccine performance in endemic regions of Kenya | 000 | 4 | NIH | 2/13/2025 | $958,026 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | T32GM159591 | Medical Scientist Training at UMCMS | 000 | 1 | NIH | 8/6/2025 | $1,003,507 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31HL180004 | Investigating the role of endothelial and fibroblastic reticular cells in lung inflammation caused by STING gain-of-function autoinflammation | 000 | 1 | NIH | 7/30/2025 | $37,577 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01CA305435 | MEDUSA(GM): an analysis platform for resolving mechanisms of action for anti-cancer drugs | 000 | 1 | NIH | 8/6/2025 | $415,491 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NS145295 | Evaluating the efficiency of in vivo gene transfer to correct the molecular neuropathology causing psychiatric disease in MSUD | 000 | 1 | NIH | 7/30/2025 | $613,528 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31HL180004 | Investigating the role of endothelial and fibroblastic reticular cells in lung inflammation caused by STING gain-of-function autoinflammation | 001 | 1 | NIH | 7/30/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM160300 | Decoding cis-regulatory element activity through deep learning frameworks | 000 | 1 | NIH | 8/6/2025 | $460,625 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R24AI192252 | Fungal Antigen Resources for Development of Vaccines and Diagnostics | 000 | 1 | NIH | 7/21/2025 | $1,193,457 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R37AI155901 | The role of TLRs, Type II IFN and Type III IFN in a Murine Model of Autoinflammation | 000 | 5 | NIH | 2/12/2025 | $494,929 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NS111990 | Multi-Targeting Oligonucleotide Therapeutics for Familial and Sporadic Amyotrophic Lateral Sclerosis | 002 | 7 | NIH | 5/13/2025 | $665,737 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01AI168640 | Parsing cholesterol metabolite regulation of skin immunocytes in children to identify archetypes of human neonatal immune system | 000 | 4 | NIH | 2/12/2025 | $792,392 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R25GM160996 | Mentorship Education to Advance Biomedical Research Career Development | 000 | 1 | NIH | 8/19/2025 | $541,331 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01DA063146 | Discovery and functional characterization of long non-coding RNAs in opioid use disorder within the context of HIV at single cell resolution | 000 | 1 | NIH | 7/4/2025 | $585,975 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AR086572 | Development of a long-lasting, bone-targeted gene therapy for osteogenesis imperfecta | 000 | 1 | NIH | 7/4/2025 | $667,125 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R00AR082987 | Developing a programmable siRNA-based therapeutic platform for gene silencing in the skin | 000 | 3 | NIH | 6/30/2025 | $249,000 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM160085 | Modeling Aneuploidy-Driven Phenotypes Across Tissues | 000 | 1 | NIH | 8/17/2025 | $460,625 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | RF1MH128275 | Validating Measures and Unpacking Differences in Service Use for Diverse Children with Autism | 000 | 4 | NIH | 8/18/2025 | $1,514,570 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R00NS127857 | Dissection of Cell Type Specific Contributions to Motor Learning Circuits | 000 | 3 | NIH | 8/7/2025 | $224,100 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | P50AR080593 | Dissecting Functional Autoimmunity through High-Resolution Multiomics in a Vitiligo Center of Research Translation (V-CoRT) | 002 | 4 | NIH | 8/7/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | P50AR080593 | Dissecting Functional Autoimmunity through High-Resolution Multiomics in a Vitiligo Center of Research Translation (V-CoRT) | 001 | 4 | NIH | 7/15/2025 | $1,495,911 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | UH3HL145266 | 1/2 Prospective tReatment EffiCacy in IPF uSlng genOtype for Nac Selection (PRECISIONS) trial and Molecular Endophenotyping in Idiopathic Pulmonary Fibrosis and Interstitial Lung Diseases study | 006 | 7 | NIH | 7/3/2025 | $108,582 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R37CA282805 | Uncovering the heterogenous role of senescence in prostate immune suppression and tumorigenesis | 002 | 2 | NIH | 9/4/2025 | $53,809 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | UH3HL145266 | 1/2 Prospective tReatment EffiCacy in IPF uSlng genOtype for Nac Selection (PRECISIONS) trial and Molecular Endophenotyping in Idiopathic Pulmonary Fibrosis and Interstitial Lung Diseases study | 002 | 7 | NIH | 3/26/2025 | $977,233 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R37CA282805 | Uncovering the heterogenous role of senescence in prostate immune suppression and tumorigenesis | 001 | 2 | NIH | 5/22/2025 | $38,315 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R37CA282805 | Uncovering the heterogenous role of senescence in prostate immune suppression and tumorigenesis | 000 | 2 | NIH | 3/7/2025 | $344,841 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K24DA063801 | Mentoring in Patient Oriented Research for Digital Biomarker-Driven Solutions to prevent and Treat Opioid Use Disorder | 001 | 1 | NIH | 9/17/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01HL180833 | The Role of Perivascular Adipose Tissue in Atherosclerotic Cardiovascular Disease (PVAT-ASCVD) | 000 | 1 | NIH | 8/27/2025 | $762,969 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K24DA063801 | Mentoring in Patient Oriented Research for Digital Biomarker-Driven Solutions to prevent and Treat Opioid Use Disorder | 000 | 1 | NIH | 8/25/2025 | $144,252 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM160536 | Causal inference of common and personalized single-cell gene regulatory networks | 000 | 1 | NIH | 8/25/2025 | $460,625 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01MH113743 | Microglia-Astrocyte Crosstalk Regulating SynapseRemodeling | 000 | 9 | NIH | 3/5/2025 | $459,516 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01MH113743 | Microglia-Astrocyte Crosstalk Regulating SynapseRemodeling | 001 | 9 | NIH | 9/17/2025 | $81,092 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31HD118787 | Probing the Mammalian piRISC Cleavage Mechanism | 001 | 1 | NIH | 7/24/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31HD118787 | Probing the Mammalian piRISC Cleavage Mechanism | 000 | 1 | NIH | 7/24/2025 | $34,370 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31CA290716 | Identifying and targeting the genetic determinants of immune suppression and immunotherapy failure in prostate cancer. | 001 | 1 | NIH | 7/14/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01HD095060 | Social Media and Risk-reduction Training for Preterm Infant Care Practices (SMART Preemie) | 002 | 7 | NIH | 6/3/2025 | $711,681 |
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