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 | Issue Date FY: 2025 ( Subtotal = $172,516,972 ) (Continued on the next page) |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01HL165787 | Mechanisms of STING-driven autoinflammation | 000 | 3 | NIH | 7/2/2025 | $837,240 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01GM148832 | Selenoprotein-independent biological roles for selenium in selenium deficiency and excess | 000 | 3 | NIH | 6/20/2025 | $343,375 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AA031010 | Evaluating Signs of Safety: A Deaf-Accessible Therapy Toolkit for AUD and Trauma | 000 | 3 | NIH | 8/14/2025 | $749,382 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K08CA283304 | Facilitation of Information Exchange for Shared Decision Making for Lung Cancer Screening | 000 | 3 | NIH | 6/27/2025 | $229,988 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21HD114519 | Exploring sustained implementation and fidelity of an evidence-based HIV prevention program | 001 | 2 | NIH | 8/11/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21HD114519 | Exploring sustained implementation and fidelity of an evidence-based HIV prevention program | 002 | 2 | NIH | 8/12/2025 | $50,620 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21HD114519 | Exploring sustained implementation and fidelity of an evidence-based HIV prevention program | 000 | 2 | NIH | 8/7/2025 | $137,149 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35HL171534 | Developmental origins of pericyte heterogeneity | 000 | 2 | NIH | 1/3/2025 | $1,055,250 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI180971 | Reprogramming of the innate immunometabolism by bacterial biofilms | 000 | 2 | NIH | 11/6/2024 | $200,475 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI173076 | Novel histone-binding C-type lectin receptors and their role in sterile inflammation and tissue injury | 000 | 3 | NIH | 11/6/2024 | $576,048 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NS106985 | A Chemosensory-Mechanotransduction System Regulating Ventricular Size and Brain Function | 000 | 6 | NIH | 4/9/2025 | $555,440 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F30HL176024 | Developing a novel adenine base editor tool for in vivo alpha-1 antitrypsin deficiency gene correction. | 000 | 2 | NIH | 8/8/2025 | $34,344 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | P40OD028116 | Nonhuman Primate Antibody Resource for Immune Cell Depletion | 002 | 6 | NIH | 5/2/2025 | $209,355 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | P40OD028116 | Nonhuman Primate Antibody Resource for Immune Cell Depletion | 000 | 6 | NIH | 1/13/2025 | $496,815 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | P40OD028116 | Nonhuman Primate Antibody Resource for Immune Cell Depletion | 003 | 6 | NIH | 7/21/2025 | $139,395 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AG083881 | Transcriptomics-based identification of cell type specific host genes and gene networks perturbed by HSV-1 in cerebral organoids. | 001 | 2 | NIH | 6/12/2025 | $67,000 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AG083881 | Transcriptomics-based identification of cell type specific host genes and gene networks perturbed by HSV-1 in cerebral organoids. | 000 | 2 | NIH | 4/17/2025 | $753,743 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NR020439 | Structural Racism and Engagement of Family Caregivers in Serious Illness Care | 002 | 4 | NIH | 7/3/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NR020439 | Structural Racism and Engagement of Family Caregivers in Serious Illness Care | 001 | 4 | NIH | 5/22/2025 | $70,212 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI189316 | Mechanisms of HIV accessory protein mediated control of NK cell function | 000 | 1 | NIH | 7/23/2025 | $848,839 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01MH113743 | Microglia-Astrocyte Crosstalk Regulating SynapseRemodeling | 000 | 9 | NIH | 3/5/2025 | $459,516 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01HD095060 | Social Media and Risk-reduction Training for Preterm Infant Care Practices (SMART Preemie) | 002 | 7 | NIH | 6/3/2025 | $711,681 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01DA062441 | Role of Striatal Molecular Rhythms in Sleep and Opioid Use Disorder | 000 | 1 | NIH | 7/23/2025 | $825,383 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21NS143203 | Investigating the role of TDP-43 citrullination in ALS pathogenesis | 000 | 1 | NIH | 5/27/2025 | $460,625 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31AI191745 | Investigating a hemagglutinin mediated molecular mechanism of avian influenza A virus host tropism | 002 | 1 | NIH | 6/18/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31AI191745 | Investigating a hemagglutinin mediated molecular mechanism of avian influenza A virus host tropism | 001 | 1 | NIH | 6/18/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31AI191745 | Investigating a hemagglutinin mediated molecular mechanism of avian influenza A virus host tropism | 000 | 1 | NIH | 6/18/2025 | $49,538 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R34AI195134 | AAV-delivery of broadly neutralizing antibodies to augment ART-free control of HIV-1 in children | 000 | 1 | NIH | 8/5/2025 | $251,250 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NS145295 | Evaluating the efficiency of in vivo gene transfer to correct the molecular neuropathology causing psychiatric disease in MSUD | 000 | 1 | NIH | 7/30/2025 | $613,528 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM160300 | Decoding cis-regulatory element activity through deep learning frameworks | 000 | 1 | NIH | 8/6/2025 | $460,625 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01NS145218 | Precision Editing of Granulin Mutations that Cause Frontotemporal Dementia | 000 | 1 | NIH | 8/7/2025 | $6,580,415 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R24AI192252 | Fungal Antigen Resources for Development of Vaccines and Diagnostics | 000 | 1 | NIH | 7/21/2025 | $1,193,457 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01AI168640 | Parsing cholesterol metabolite regulation of skin immunocytes in children to identify archetypes of human neonatal immune system | 000 | 4 | NIH | 2/12/2025 | $792,392 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R00NS127857 | Dissection of Cell Type Specific Contributions to Motor Learning Circuits | 000 | 3 | NIH | 8/7/2025 | $224,100 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R37AI155901 | The role of TLRs, Type II IFN and Type III IFN in a Murine Model of Autoinflammation | 000 | 5 | NIH | 2/12/2025 | $494,929 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | P50AR080593 | Dissecting Functional Autoimmunity through High-Resolution Multiomics in a Vitiligo Center of Research Translation (V-CoRT) | 002 | 4 | NIH | 8/7/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | P50AR080593 | Dissecting Functional Autoimmunity through High-Resolution Multiomics in a Vitiligo Center of Research Translation (V-CoRT) | 001 | 4 | NIH | 7/15/2025 | $1,495,911 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NS111990 | Multi-Targeting Oligonucleotide Therapeutics for Familial and Sporadic Amyotrophic Lateral Sclerosis | 002 | 7 | NIH | 5/13/2025 | $665,737 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31HL180004 | Investigating the role of endothelial and fibroblastic reticular cells in lung inflammation caused by STING gain-of-function autoinflammation | 000 | 1 | NIH | 7/30/2025 | $37,577 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01CA305435 | MEDUSA(GM): an analysis platform for resolving mechanisms of action for anti-cancer drugs | 000 | 1 | NIH | 8/6/2025 | $415,491 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01AI165524 | A systems immunology approach to evaluate malaria vaccine performance in endemic regions of Kenya | 000 | 4 | NIH | 2/13/2025 | $958,026 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | T32GM159591 | Medical Scientist Training at UMCMS | 000 | 1 | NIH | 8/6/2025 | $1,003,507 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AR086572 | Development of a long-lasting, bone-targeted gene therapy for osteogenesis imperfecta | 000 | 1 | NIH | 7/4/2025 | $667,125 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R00AR082987 | Developing a programmable siRNA-based therapeutic platform for gene silencing in the skin | 000 | 3 | NIH | 6/30/2025 | $249,000 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01DA063146 | Discovery and functional characterization of long non-coding RNAs in opioid use disorder within the context of HIV at single cell resolution | 000 | 1 | NIH | 7/4/2025 | $585,975 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI192333 | PROTECTIVE CD8 T CELL RESPONSES to TUBERCULOSIS | 000 | 1 | NIH | 8/8/2025 | $832,076 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31CA290716 | Identifying and targeting the genetic determinants of immune suppression and immunotherapy failure in prostate cancer. | 001 | 1 | NIH | 7/14/2025 | $0 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31CA290716 | Identifying and targeting the genetic determinants of immune suppression and immunotherapy failure in prostate cancer. | 000 | 1 | NIH | 7/14/2025 | $34,454 |
| | 2025 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R33NS130604 | Comprehensive Harmonization and Analysis of Case/Control Whole Genome Sequencing Data from the ALS/FTD Compute Project | 000 | 2 | NIH | 7/15/2025 | $817,388 |
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