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 | Issue Date FY: 2026 ( Subtotal = $20,793,442 ) (Continued on the next page) |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31GM157877 | Engineering bacterial group I introns for efficient production of safe and durable nucleoside-modified circular mRNA therapeutics | 000 | 2 | NIH | 1/6/2026 | $33,780 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01AI165524 | A systems immunology approach to evaluate malaria vaccine performance in endemic regions of Kenya | 000 | 5 | NIH | 1/30/2026 | $890,974 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AG067483 | Understanding the Microbiome-gut-brain axis in Alzheimers disease and its Role | 001 | 3 | NIH | 1/30/2026 | $703,465 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM122597 | RNA and Genomic Junk in Fundamental Chromosome Architecture and Regulation | 000 | 9 | NIH | 1/28/2026 | $557,571 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NS076991 | Oligodendrocyte-focused rAAV gene therapy strategies for Canavan disease and Leukodystrophies | 000 | 12 | NIH | 1/28/2026 | $477,390 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AG092770 | Aging Impairs Wound Healing by an HSC-Autonomous Mechanism | 000 | 1 | NIH | 1/28/2026 | $626,409 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01MD018611 | Motivational Interviewing Training to Promote COVID-19 and Influenza Vaccination (MI-VAX): What Providers Need and Patients Want | 000 | 3 | NIH | 1/25/2026 | $638,359 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01GM060992 | Intraflagellar Transport Proteins in Mice | 000 | 25 | NIH | 1/27/2026 | $408,137 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | T32HL171799 | CardiOvascular Digital hEalth Research (CODER) Training Program | 000 | 3 | NIH | 1/26/2026 | $304,077 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K23HL163450 | Development of a Mobile Health Intervention for Blood Pressure Management in Pregnancy | 000 | 3 | NIH | 1/27/2026 | $189,050 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | T32GM135751 | IMSD at the University of Massachusetts Chan Medical School | 000 | 7 | NIH | 1/23/2026 | $477,768 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01AI168640 | Parsing cholesterol metabolite regulation of skin immunocytes in children to identify archetypes of human neonatal immune system | 000 | 5 | NIH | 1/30/2026 | $816,899 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AR078230 | Novel approaches to promote healing of bone loss in inflammatory arthritis | 000 | 5 | NIH | 1/30/2026 | $474,777 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K99NS136849 | Advanced Base and Prime Editing Strategies to Correct Common ALS-causing SOD1 Mutations | 000 | 2 | NIH | 12/15/2025 | $124,246 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI183080 | In vitro and in vivo modeling of gene therapy vector stability when challenged by natural virus infection in human hepatocytes | 000 | 2 | NIH | 11/28/2025 | $167,500 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI189245 | Discovery of viral and host pathways that protect HIV-infected macrophages from NK cell ADCC | 000 | 2 | NIH | 12/19/2025 | $209,375 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI185024 | Immunobiology of a novel human DAMP receptor, its murine homolog, & their ligand | 000 | 2 | NIH | 12/19/2025 | $595,972 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R03AI190223 | Molecular and metabolic characterization of gut stromal cells underpinning efficient intestinal B cell response | 000 | 2 | NIH | 12/19/2025 | $83,750 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01DK126804 | Extracellular protease modulation of the cilium transition zone in kidney development and disease | 000 | 5 | NIH | 12/19/2025 | $368,500 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R00MD017269 | Effects of Early and Prolonged Parent-Child Separation: Understanding Mental Health among Separated-Reunited Chinese American Children | 000 | 5 | NIH | 12/18/2025 | $248,915 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI182355 | Combining B. thuringiensis crystal proteins with small molecule anthelmintics to combat parasitic nematode resistance | 000 | 2 | NIH | 11/25/2025 | $723,130 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AG075283 | Aging Microbiome, Immunosenescence, and risk of Multi-drug Resistant Organism Colonization and Infection in the Nursing Home | 000 | 4 | NIH | 12/4/2025 | $632,299 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI173076 | Novel histone-binding C-type lectin receptors and their role in sterile inflammation and tissue injury | 000 | 4 | NIH | 11/25/2025 | $593,865 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI060025 | From Drosophila Immunity to Anti-Inflammatories | 000 | 22 | NIH | 12/29/2025 | $611,172 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI182052 | Regulation of the NLRP1 inflammasome by HSV-1 | 000 | 2 | NIH | 11/26/2025 | $671,097 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AG089801 | Elucidation of the mechanisms by which Ms4a genes regulate neurodegeneration in Alzheimer's Disease and related disorders | 000 | 1 | NIH | 12/23/2025 | $445,130 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI187460 | Generation & Regulation of Tfh13 cells that drive Pathogenic IgE in Allergy | 000 | 2 | NIH | 11/25/2025 | $586,250 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K08AI180429 | The Role of ADAM9 in the Innate Immune Response to SARS-CoV-2 Infection | 000 | 2 | NIH | 12/8/2025 | $190,058 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI158832 | Cholesterol metabolites coordinate skin barrier immunity centered on innate dermal gammadelta T cells programmed to produce IL-17 | 000 | 5 | NIH | 11/25/2025 | $707,833 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01CA269711 | Targeting the detoxification function of the enzyme KDSR for cancer therapy | 000 | 4 | NIH | 12/18/2025 | $344,341 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01AI184042 | Ectodomain shedding and HIV replication | 000 | 3 | NIH | 12/18/2025 | $736,427 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F30AI181515 | Characterization of Enterovirus 68 3C Protease For the Development of Robust and Potent Direct-Acting Antiviral Inhibitors | 000 | 3 | NIH | 12/16/2025 | $57,538 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM156361 | Structural mechanisms of multimeric ATPases | 000 | 2 | NIH | 12/16/2025 | $602,353 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | U01AI172987 | Development of targeted microbiome therapeutics and dietary interventions for potent intestinal barrier promotion to minimize GI-ARS | 000 | 4 | NIH | 12/16/2025 | $586,150 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R21AI191052 | Comprehensive analysis of epistasis in drug resistance potential of Mpro from SARS-CoV-2 | 000 | 2 | NIH | 2/6/2026 | $209,375 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01NR020439 | Structural Racism and Engagement of Family Caregivers in Serious Illness Care | 000 | 5 | NIH | 1/30/2026 | $617,496 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01EB037025 | Synthetic RNA Switch-Based Temporal and Dose Control of in Vivo Gene Therapies | 000 | 2 | NIH | 2/2/2026 | $487,740 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM133762 | Tracking transcriptome diversity in real-time | 000 | 7 | NIH | 12/23/2025 | $431,145 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31NS143315 | Molecular Regulation of Foraging Behavior by the Nervous System | 000 | 1 | NIH | 1/1/2026 | $35,626 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | UG3DK142192 | Models to study the synergy between autoimmunity and metabolism in T1D | 000 | 2 | NIH | 1/21/2026 | $1,152,518 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | P40OD028116 | Nonhuman Primate Antibody Resource for Immune Cell Depletion | 000 | 7 | NIH | 1/21/2026 | $685,776 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35GM131741 | Genetic control of developmental timing | 000 | 7 | NIH | 1/9/2026 | $759,840 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | K01HL163254 | ActivityChoice: A clinic-delivered implementation program to increase physical activity and decrease cardiovascular disease risk amongst cancer survivors | 000 | 4 | NIH | 1/15/2026 | $162,485 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31GM157877 | Engineering bacterial group I introns for efficient production of safe and durable nucleoside-modified circular mRNA therapeutics | 001 | 2 | NIH | 1/14/2026 | $564 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R35HL171534 | Developmental origins of pericyte heterogeneity | 000 | 3 | NIH | 2/2/2026 | $1,113,874 |
| | 2026 | 2026 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F30DA058525 | Implementation of Medications for Opioid Use Disorder in Massachusetts Jails | 000 | 3 | NIH | 1/8/2026 | $33,538 |
| | 2026 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | R01GM145062 | Post-transcriptional regulation of germline mRNAs in C. elegans | 000 | 4 | NIH | 2/3/2026 | $0 |
| | 2026 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | TR753199 | Regional AIDS Education and Training Centers Program | 03 | 2 | HRSA | 1/28/2026 | $0 |
| | 2026 | 2025 | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 55 LAKE AVE N | WORCESTER | MA | 01655-0002 | WORCESTER | USA | F31NS127555 | Establishing and Optimizing a Prime Editing Method in Neurons for Treatment of Rett Syndrome | 000 | 3 | NIH | 1/27/2026 | -$6,727 |
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