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Human Health Exposure Analysis Resource (HHEAR) Data Center

Award Number: U2CES026555
ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/30/2015
PERIOD OF PERFORMANCE END DATE: 12/31/2025

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Human Health Exposure Analysis Resource (HHEAR) Data Center - OVERALL PROJECT SUMMARY To capture the full effects of environmental exposures on human health outcomes, the National Institute of Environmental Health Sciences (NIEHS) is expanding the focus of the Children's Health Exposure Analysis Resource (CHEAR) to encompass health across the lifecourse: the Human Health Exposure Analysis Resource (HHEAR). The Icahn School of Medicine at Mount Sinai is applying to be the HHEAR Data Center, providing intellectual and logistical support for the maintenance, analysis, interpretation, curation, and reuse of data generated by HHEAR in support of extramural research projects. Since 2015, we at Mount Sinai, in collaboration with data scientists at Rensselaer Polytechnic Institute, have served as the CHEAR Data Center, supporting studies of children's environmental health research. We propose to build on our established infrastructure, expertise, and experience as the CHEAR Data Center to provide a repository for all data and support for statistical analysis and interpretation for investigators using the data generated within and outside the network. The HHEAR Data Center will provide: 1) data repository and management resources; 2) data science resources; 3) statistical consultation and analysis services; and 4) collaborative research support. Through these efforts, we seek to ultimately maximize the potential use and impact of exposure data both within and outside of HHEAR. Indeed, investigators who access resources provided by the HHEAR Data Center will leverage the potential of big data to accelerate environmental health studies far beyond their original funded goals, and potentially accomplish research that was previously thought infeasible or too costly. The HHEAR Data Center is critical to advancing the scientific community's ability to examine the environment on an exposome scale: the design of the Data Repository will facilitate manageable and efficient combining of existing data sets; the availability of common vocabularies developed by the Data Science Resource will contribute to maximizing the usable data from each study; and the Statistical Services and Analysis Resource will ultimately apply their exposome-related analytic methods to address hypotheses on the environmental health of pooled study populations. Further, the Data Center leadership comprises world leaders in Environmental Epidemiology, Computer Science, Environmental Biostatistics, and Ontology, already working together as the CHEAR Data Center, who are eager to continue and expand their efforts in service of the HHEAR Network. Our existing Data Center will be expanded in both resources and infrastructure, including through significant institutional support, to meet the requirements of the HHEAR Network. Thus, we at Mount Sinai are uniquely positioned to provide a state-of-the-art Data Center for the environmental health research community.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2025	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	1 GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	000	8	11/25/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2025 ( Subtotal = $1,455,970 )
2025	2025	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	1 GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	002	8	6/5/2025	NON-COMPETING CONTINUATION	$1,455,970
2025	2024	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	1 GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	001	7	10/17/2024	EXTENSION WITH OR WITHOUT FUNDS	$377,281
2025	2023	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	1 GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	000	6	10/17/2024	NON-COMPETING CONTINUATION	-$377,281
														Subtotal = $1,455,970

Issue Date FY: 2024 ( Subtotal = $2,065,803 )
2024	2024	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	1 GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	001	7	5/29/2024	EXTENSION WITH OR WITHOUT FUNDS	$2,065,803
2024	2024	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	1 GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	002	7	6/19/2024	EXTENSION WITH OR WITHOUT FUNDS	$0
2024	2023	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	1 GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	000	6	3/14/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,065,803

Issue Date FY: 2023 ( Subtotal = $2,602,634 )
2023	2023	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	002	6	8/9/2023	SUPPLEMENT FOR EXPANSION	$98,677
2023	2023	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	001	6	5/22/2023	NON-COMPETING CONTINUATION	$2,503,957
2023	2022	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	000	5	2/24/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,602,634

Issue Date FY: 2022 ( Subtotal = $2,755,589 )
2022	2022	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	001	5	8/29/2022	SUPPLEMENT FOR EXPANSION	$251,633
2022	2022	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	000	5	8/16/2022	NON-COMPETING CONTINUATION	$2,503,956
														Subtotal = $2,755,589

Issue Date FY: 2021 ( Subtotal = $2,786,000 )
2021	2021	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	002	4	6/8/2021	NON-COMPETING CONTINUATION	$2,786,000
2021	2020	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	001	3	4/16/2021	NON-COMPETING CONTINUATION	$0
2021	2020	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	000	3	11/19/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,786,000

Issue Date FY: 2020 ( Subtotal = $2,500,000 )
2020	2020	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	005	3	5/28/2020	NON-COMPETING CONTINUATION	$2,500,000
2020	2020	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	006	3	8/31/2020	NON-COMPETING CONTINUATION	$0
2020	2019	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	004	2	2/3/2020	COMPETING CONTINUATION	$997,716
2020	2018	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	003	1	2/3/2020	SUPPLEMENT FOR EXPANSION	-$129,884
2020	2017	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Trans-NIH Research Support	002	1	2/3/2020	SUPPLEMENT FOR EXPANSION	-$294,406
2020	2016	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Trans-NIH Research Support	001	1	2/3/2020	SUPPLEMENT FOR EXPANSION	-$301,009
2020	2015	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Trans-NIH Research Support	000	1	2/3/2020	NEW	-$272,417
														Subtotal = $2,500,000

Issue Date FY: 2019 ( Subtotal = $2,503,957 )
2019	2019	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	001	2	9/3/2019	COMPETING CONTINUATION	$2,503,957
2019	2015	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Trans-NIH Research Support	000	1	10/25/2018	NEW	$0
														Subtotal = $2,503,957

Issue Date FY: 2018 ( Subtotal = $129,884 )
2018	2018	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Environmental Health	000	1	9/15/2018	SUPPLEMENT FOR EXPANSION	$129,884
														Subtotal = $129,884

Issue Date FY: 2017 ( Subtotal = $294,406 )
2017	2017	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	ONE GUSTAVE L LEVY PL	NEW YORK	NY	10029	NEW YORK	USA	Trans-NIH Research Support	000	1	9/19/2017	SUPPLEMENT FOR EXPANSION	$294,406
														Subtotal = $294,406

Issue Date FY: 2016 ( Subtotal = $301,009 )
2016	2016	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	1 GUSTAVE L LEVY PL, BOX 3500	NEW YORK-NEW YORK	NY	10029		USA	Trans-NIH Research Support	000	1	9/21/2016	SUPPLEMENT FOR EXPANSION	$301,009
														Subtotal = $301,009

Issue Date FY: 2015 ( Subtotal = $9,000,000 )
2015	2015	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	1 GUSTAVE L LEVY PL, BOX 3500	NEW YORK-NEW YORK	NY	10029		USA	Trans-NIH Research Support	000	1	9/22/2015	NEW	$9,000,000
														Subtotal = $9,000,000

Grand Total All Awards = $26,395,252

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Human Health Exposure Analysis Resource (HHEAR) Data Center

Award Number: U2CES026555

ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/30/2015

PERIOD OF PERFORMANCE END DATE: 12/31/2025

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