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Wadsworth Center's Human Health and Exposure Analysis Resource (WC-HHEAR)

Award Number: U2CES026542
ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 04/26/2025
PERIOD OF PERFORMANCE END DATE: 05/31/2026

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Wadsworth Center's Human Health and Exposure Analysis Resource (WC-HHEAR) - PROJECT SUMMARY / ABSTRACT The overall objective of this supplement proposal is to provide the Wadsworth Center’s Human Health and Exposure Analysis Resource (WC-HHEAR) the resources to support unanticipated additional work associated with the Chronic Kidney Disease of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE) Research Consortium. WC-HHEAR provides CURE with access to state-of-the-art analyses for exploring the effects of environmental contaminants on chronic kidney disease. WC-HHEAR’s extensive infrastructure, expertise, and reputation as a world-class trace elements laboratory located within the NY State Department of Health’s Wadsworth Center is widely recognized. Within the Center’s Division of Environmental Health Sciences (DEHS), biospecimens are analyzed for toxic metals within the Trace Elements Lab (TREL). Dr. Patrick Parsons is the Director of DEHS and is the Principal Investigator for the TREL. Dr. Parsons has more than 40 years of experience in analytical chemistry applied to measuring trace elements in human tissues and body fluids. The TREL group analyzes biospecimens for up to 41 trace elements that include toxic (lead, cadmium, mercury, and arsenic) and essential (copper, selenium, zinc) elements in whole blood, urine, and serum/plasma, plus the 16 rare earth elements, which includes the lanthanides series. The TREL has extensive expertise analyzing non- traditional matrices such as placenta, cord blood, baby teeth, dried blood spots, hair, nails, amniotic fluid, breast milk, saliva, and other tissues. This supplement leverages Wadsworth’s capacity and capability to provide high complexity laboratory analyses to support the additional needs of the CURE consortium. Specifically, WC- HHEAR has the capability and capacity to analyze an additional 600 blood specimens for 24 trace elements and an additional 600 urine specimens for 24 trace elements using well validated clinical methods based on tandem inductively coupled plasma mass spectrometry (ICP-MS/MS). Since WC-HHEAR is a CLIA-certified laboratory, some of these test results may be reported back to study subjects. In addition to analyzing 600 urine specimens for a suite of trace elements, WC-HHEAR has the capability and capacity to analyze 300 urine specimens for 5 arsenic species using a well validated method based on Liquid Chromatography coupled to ICP-MS/MS.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $100,000 )
2025	2025	HEALTH RESEARCH, INC.	150 BROADWAY STE 280	MENANDS	NY	12204	ALBANY	USA	Environmental Health	002	6	7/17/2025	SUPPLEMENT FOR EXPANSION	$100,000
2025	2024	HEALTH RESEARCH, INC.	150 BROADWAY STE 280	MENANDS	NY	12204	ALBANY	USA	Environmental Health	001	6	7/16/2025	NON-COMPETING CONTINUATION	$0
2025	2024	HEALTH RESEARCH, INC.	150 BROADWAY STE 280	MENANDS	NY	12204	ALBANY	USA	Environmental Health	000	6	12/12/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $100,000

Issue Date FY: 2024 ( Subtotal = $1,120,284 )
2024	2024	HEALTH RESEARCH, INC.	150 BROADWAY STE 280	MENANDS	NY	12204	ALBANY	USA	Environmental Health	000	6	5/17/2024	NON-COMPETING CONTINUATION	$1,120,284
														Subtotal = $1,120,284

Issue Date FY: 2023 ( Subtotal = $2,435,144 )
2023	2023	HEALTH RESEARCH, INC.	STE 280, RIVERVIEW CENTER	MENANDS	NY	12204	ALBANY	USA	Environmental Health	001	5	8/8/2023	SUPPLEMENT FOR EXPANSION	$946,826
2023	2023	HEALTH RESEARCH, INC.	STE 280, RIVERVIEW CENTER	MENANDS	NY	12204	ALBANY	USA	Environmental Health	000	5	5/30/2023	NON-COMPETING CONTINUATION	$1,488,318
														Subtotal = $2,435,144

Issue Date FY: 2022 ( Subtotal = $0 )
2022	2021	HEALTH RESEARCH, INC.	EMPIRE STATE PLAZA	ALBANY	NY	12237	ALBANY	USA	Environmental Health	001	4	5/19/2022	NON-COMPETING CONTINUATION	$0
2022	2021	HEALTH RESEARCH, INC.	EMPIRE STATE PLAZA	ALBANY	NY	12237	ALBANY	USA	Environmental Health	000	4	2/1/2022	NON-COMPETING CONTINUATION	$0
2022	2021	HEALTH RESEARCH, INC.	EMPIRE STATE PLAZA	ALBANY	NY	12237	ALBANY	USA	Environmental Health	002	4	6/13/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2021 ( Subtotal = $2,271,517 )
2021	2021	HEALTH RESEARCH, INC.	EMPIRE STATE PLAZA	ALBANY	NY	12237	ALBANY	USA	Environmental Health	001	4	6/18/2021	NON-COMPETING CONTINUATION	$2,271,517
2021	2020	HEALTH RESEARCH, INC.	EMPIRE STATE PLAZA	ALBANY	NY	12237	ALBANY	USA	Environmental Health	000	3	11/24/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,271,517

Issue Date FY: 2020 ( Subtotal = $1,150,000 )
2020	2020	HEALTH RESEARCH, INC.	EMPIRE STATE PLAZA	ALBANY	NY	12237	ALBANY	USA	Environmental Health	003	3	7/23/2020	NON-COMPETING CONTINUATION	$1,150,000
2020	2019	HEALTH RESEARCH, INC.	EMPIRE STATE PLAZA	ALBANY	NY	12237	ALBANY	USA	Environmental Health	002	2	2/3/2020	COMPETING CONTINUATION	$4,030,963
2020	2018	HEALTH RESEARCH, INC.	EMPIRE STATE PLAZA	ALBANY	NY	12237	ALBANY	USA	Environmental Health	001	1	2/3/2020	SUPPLEMENT FOR EXPANSION	-$2,431,534
2020	2017	HEALTH RESEARCH, INC.	EMPIRE STATE PLAZA	ALBANY	NY	12237	ALBANY	USA	Trans-NIH Research Support	000	1	2/3/2020	SUPPLEMENT FOR EXPANSION	-$1,599,429
														Subtotal = $1,150,000

Issue Date FY: 2019 ( Subtotal = $1,650,001 )
2019	2019	HEALTH RESEARCH, INC.	EMPIRE STATE PLAZA	ALBANY	NY	12237	ALBANY	USA	Environmental Health	000	2	9/4/2019	COMPETING CONTINUATION	$1,650,001
														Subtotal = $1,650,001

Issue Date FY: 2018 ( Subtotal = $2,431,534 )
2018	2018	HEALTH RESEARCH, INC.	EMPIRE STATE PLAZA	ALBANY	NY	12237	ALBANY	USA	Environmental Health	000	1	9/15/2018	SUPPLEMENT FOR EXPANSION	$2,431,534
														Subtotal = $2,431,534

Issue Date FY: 2017 ( Subtotal = $2,080,000 )
2017	2017	HEALTH RESEARCH, INC.	EMPIRE STATE PLAZA	ALBANY	NY	12237	ALBANY	USA	Trans-NIH Research Support	000	1	9/19/2017	SUPPLEMENT FOR EXPANSION	$2,080,000
														Subtotal = $2,080,000

Issue Date FY: 2016 ( Subtotal = $1,199,106 )
2016	2016	HEALTH RESEARCH, INC - ALBANY DIVISION	1 UNIVERSITY PLACE	RENSSELAER	NY	12144	RENSSELAER	USA	Trans-NIH Research Support	000	1	9/21/2016	SUPPLEMENT FOR EXPANSION	$1,199,106
														Subtotal = $1,199,106

Issue Date FY: 2015 ( Subtotal = $1,126,276 )
2015	2015	HEALTH RESEARCH, INC - ALBANY DIVISION	1 UNIVERSITY PLACE	RENSSELAER	NY	12144	RENSSELAER	USA	Trans-NIH Research Support	000	1	9/24/2015	NEW	$1,126,276
														Subtotal = $1,126,276

Grand Total All Awards = $15,563,862

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Wadsworth Center's Human Health and Exposure Analysis Resource (WC-HHEAR)

Award Number: U2CES026542

ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 04/26/2025

PERIOD OF PERFORMANCE END DATE: 05/31/2026

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