Thursday, October 2, 2025 10/2/2025

Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS)

Award Number: U2CCA252981
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/01/2021
PERIOD OF PERFORMANCE END DATE: 08/31/2027

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Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS) - Participant engagement and genomic sequencing research from the Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS) will fill critical gaps in knowledge, methodology, and characterization of cancer populations requiring more research, leading to optimal approaches for participant engagement, outreach, and communication in genomic characterization studies. Our overall goal is to build a rigorous, scientific evidence base for approaches on direct engagement of patients and post-treatment cancer survivors as research participants. Our focus is on rare cancers in populations with significant adverse outcomes (cholangiocarcinoma, multiple myeloma, and colorectal cancer). Our Center will be housed in an environment that fosters multidisciplinary collaboration, catalyzes new ideas, and ensures support that finds solutions for complex recruitment and engagement challenges. The specific aims are to: (1) Advance the field of participant engagement to study adverse cancer outcomes by conducting innovative and impactful direct stakeholder engagement with continuous evaluation and research; (2) Expand an exceptional, broad team of investigators, patients, and patient interest stakeholders; (3) Address adverse cancer outcomes by understanding challenges and improving the ability for low-resourced populations requiring more research to encounter, use, and benefit from genomic sequencing and analysis; (4) Organize and integrate Center units to facilitate team science within our Center and across the Network. WU-PE-CGS builds on a long, outstanding leadership record in cancer and genomic research across the cancer continuum and will enable a significant return on scientific investment in several ways. First, our Center has distinctive features, including a combined focus on adverse cancer outcomes, application of strategies to increase participant engagement, biospecimen acquisition success, and exceptional genomic sequencing expertise. Second, we have assembled a broad, world-class team with strong links to multiple rare cancers. Third, we engage investigators from different disciplines and invest in developing early career scholars. Fourth, we strategically and creatively disseminate products in ways that benefit researchers, practitioners, and community members. Fifth, we will partner with patient-centered interest groups to engage patients, optimize recruitment, and seamlessly return results. Finally, we developed a focused strategy for collective integration of our units. These synergies will allow us to become a national resource for optimal participant engagement, outreach, and communication approaches in genomic characterization studies, accelerating progress for researchers, patients, and their communities.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $3,543,660 )
2025	2025	WASHINGTON UNIVERSITY, THE	1 BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	001	5	9/16/2025	NON-COMPETING CONTINUATION	$3,543,660
2025	2024	WASHINGTON UNIVERSITY, THE	1 BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	000	4	7/2/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $3,543,660

Issue Date FY: 2024 ( Subtotal = $3,623,705 )
2024	2024	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63110	SAINT LOUIS CITY	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	000	4	9/11/2024	NON-COMPETING CONTINUATION	$3,814,426
2024	2024	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63110	SAINT LOUIS CITY	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	001	4	9/12/2024	NON-COMPETING CONTINUATION	-$190,721
														Subtotal = $3,623,705

Issue Date FY: 2023 ( Subtotal = $3,116,107 )
2023	2023	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	001	3	9/7/2023	NON-COMPETING CONTINUATION	$3,109,346
2023	2023	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Cause and Prevention Research	002	3	9/8/2023	SUPPLEMENT FOR EXPANSION	$4,382
2023	2022	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	000	2	12/2/2022	NON-COMPETING CONTINUATION	$2,379
														Subtotal = $3,116,107

Issue Date FY: 2022 ( Subtotal = $4,057,469 )
2022	2022	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	001	2	9/1/2022	NON-COMPETING CONTINUATION	$3,828,920
2022	2022	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Cause and Prevention Research	002	2	9/15/2022	SUPPLEMENT FOR EXPANSION	$28,540
2022	2021	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	000	1	5/2/2022	NEW	$200,009
														Subtotal = $4,057,469

Issue Date FY: 2021 ( Subtotal = $3,343,651 )
2021	2021	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	000	1	9/1/2021	NEW	$3,343,651
														Subtotal = $3,343,651

Grand Total All Awards = $17,684,592

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Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS)

Award Number: U2CCA252981

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/01/2021

PERIOD OF PERFORMANCE END DATE: 08/31/2027

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