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 | Issue Date FY: 2025 ( Subtotal = $130,306,729 ) (Continued on the next page) |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01AG081452 | Endolysosomal trafficking and lipid metabolism defects in FTLD | 001 | 3 | NIH | 3/28/2025 | $630,193 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01CA279293 | The role of SERPINB3 in cervical cancer therapeutic resistance | 000 | 2 | NIH | 3/20/2025 | $503,182 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01AG031867 | Protein aggregation in inclusion body and myofibrillar myopathies | 001 | 17 | NIH | 3/19/2025 | $585,381 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01CA289884 | Quality assurance for safe use of AI systems in radiotherapy | 000 | 2 | NIH | 3/20/2025 | $290,990 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01EY029130 | Structural, mechanical, and cell biological properties of the ciliary zonule | 000 | 7 | NIH | 3/19/2025 | $474,844 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01AG070139 | Neural and motivational mechanisms of age-related change in emotion regulation | 000 | 5 | NIH | 3/11/2025 | $794,559 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01AG084717 | Synaptic activity-driven Abeta generation and aggregation | 000 | 2 | NIH | 3/4/2025 | $619,903 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01CA237263 | DNA replication stress in cancer | 002 | 8 | NIH | 3/10/2025 | $379,502 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01AI159450 | Development of small molecule inhibitors of metabolic enzymes as broad spectrum anthelmintic drugs | 000 | 5 | NIH | 3/10/2025 | $721,872 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01DK132239 | Mitochondrial dynamics and the control of adipose tissue thermogenesis | 000 | 4 | NIH | 3/3/2025 | $349,875 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01AG081419 | Role of the microglial immune-oxysterol 25-hydroxycholesterol in mediating neuroinflammation and neurodegeneration in the P301S tau transgenic mouse model of Alzheimer's disease | 000 | 3 | NIH | 3/21/2025 | $410,704 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | K23HL171940 | Implementation of SMART therapy for asthma patients in low-resource community health centers | 000 | 2 | NIH | 2/25/2025 | $208,436 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01MD016082 | Efficacy of a Multi-level School Intervention for LGBTQ Youth | 002 | 4 | NIH | 3/23/2025 | $0 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | K01MH127412 | Suicidality in Young Children: Social and Cognitive Developmental Markers of Risk and Resiliency | 000 | 4 | NIH | 3/21/2025 | $179,399 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | K23HL173684 | Improving Maternal Cardiovascular Outcomes through the Implementation of a Hypertensive Disorders of Pregnancy Bundle in Nigeria | 000 | 2 | NIH | 2/25/2025 | $186,259 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | F30CA298121 | Dissecting how activated immunity reshapes the stromal TME of pancreatic ductal adenocarcinoma | 000 | 1 | NIH | 3/10/2025 | $35,482 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01HD108240 | Significance of Spinal Movement Impairments in Acute Low Back Pain | 000 | 3 | NIH | 3/4/2025 | $564,242 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | K08DK132496 | Neoglycosylation Epitopes in Metaplasia and Cancer | 000 | 4 | NIH | 2/18/2025 | $165,062 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01MH128232 | Bridges-Round 2: Evaluating the Long-term Impact of a Family Economic Empowerment Intervention on HIV Risk Prevention and Care Continuum Outcomes among Orphaned Youth Transitioning to Young Adulthood | 000 | 4 | NIH | 2/18/2025 | $489,799 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | K08AI184158 | Understanding the mechanism of tropism specific immune restriction in HIV infection | 000 | 1 | NIH | 2/25/2025 | $197,366 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01MH129426 | Model-Based Investigation of Aberrant Neural Face Representation in Autism | 000 | 4 | NIH | 3/21/2025 | $331,723 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01DK136749 | Covalent regulation of branched chain amino acid metabolism | 000 | 2 | NIH | 2/24/2025 | $415,604 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R35GM144282 | Molecular Mechanisms of Transcription Initiation and DNA Repair | 001 | 4 | NIH | 2/25/2025 | $419,850 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | F31CA298288 | Dissecting mechanistic differences between EZH2 gain-of-function events in B-cell lymphoma | 001 | 1 | NIH | 3/18/2025 | $0 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01DK132090 | Molecular Genetics of Hereditary Endoplasmic Reticulum Diabetes | 000 | 4 | NIH | 3/5/2025 | $486,383 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R00AG070105 | Investigating whole-body innate immune activation in Alzheimer's disease using PET imaging and immune profiling | 001 | 5 | NIH | 3/6/2025 | $224,100 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01NS090874 | High Sensitivity Diffuse Optical Tomography of Human Brain Funciton | 000 | 14 | NIH | 2/14/2025 | $496,005 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01NS134586 | Investigate neuroinflammation in the brain of PD using S1P1 radioligands | 000 | 2 | NIH | 2/14/2025 | $556,253 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01HS029324 | EnhanCed HandOffs (ECHO) | 000 | 3 | AHRQ | 3/25/2025 | $399,999 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01CA273127 | Determining the Role and Targeting potential of Serine Metabolism in aggressive sub-types of Acute Myeloid Leukemia | 000 | 3 | NIH | 2/14/2025 | $514,092 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01CA262414 | Harnessing TNFa Signaling To Improve Therapeutic Response In Pancreatic Cancer | 000 | 3 | NIH | 2/14/2025 | $542,319 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01HL177000 | Role of circulating Osteopontin and of Innate Immune Cell CD44 in Tissue Injury-induced Remote Lung Inflammation | 000 | 1 | NIH | 3/25/2025 | $583,233 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | F32AI188627 | Heme Homeostasis in the Malaria Parasite Plasmodium falciparum | 001 | 1 | NIH | 1/16/2025 | $0 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01AG073210 | White Matter Metabolism in the Context of Aging, White Matter Hyperintensities and Alzheimer's Disease | 000 | 2 | NIH | 3/25/2025 | $648,238 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | K23MH125023 | Neurodevelopmental Emergence of Callous-Unemotional Behavior Beginning in Infancy: Neural Markers and Environmental Risk and Protective Factors | 000 | 5 | NIH | 2/14/2025 | $180,721 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R00MH129983 | Gene regulatory networks influencing neuron-microglia interactions in fetal brain development. | 000 | 4 | NIH | 3/7/2025 | $204,282 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01CA260066 | Molecular Biomarkers of Long-Term Response to Androgen Deprivation Therapy and Radiation in Prostate Cancer | 001 | 4 | NIH | 2/14/2025 | $0 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01CA266041 | Understanding the role of DNA damage repair in racial disparities of triple-negative breast cancer outcomes | 000 | 4 | NIH | 3/7/2025 | $409,560 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01HL159171 | Mechanistic Studies of the Novel Human Coronary Artery Disease Gene SVEP1 | 000 | 4 | NIH | 2/14/2025 | $477,662 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01CA282733 | An RNA-Dependent Innate Immune Response Pathway to Base-Damaging Chemotherapeutics | 000 | 2 | NIH | 2/14/2025 | $440,582 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01NS134506 | Allele Specific Knockdown for LGMDD1 | 000 | 2 | NIH | 2/14/2025 | $491,100 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01HL157188 | The Impact of Cerebral Metabolic Stress on the Development of the Structural and Functional Connectome in Pediatric Sickle Cell Anemia | 000 | 5 | NIH | 3/24/2025 | $558,617 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01AG081631 | Spontaneous and Induced B cell and T cell responses in Alzheimer's Disease | 000 | 2 | NIH | 3/7/2025 | $697,726 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R21NS133823 | Therapeutic targeting of DNA methyltransferases in Huntington's disease | 000 | 2 | NIH | 2/14/2025 | $194,375 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | F30DK135390 | Novel therapeutics for treatment of catheter-associated UTI and depletion of the vaginal reservoir | 000 | 3 | NIH | 2/14/2025 | $53,974 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | F32MH140418 | Mapping Cortical Area Organization in Healthy Adults Using High-Resolution HCP Data: Insights into Human Brain Function and Morphology | 000 | 1 | NIH | 3/7/2025 | $78,328 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | F32AI188627 | Heme Homeostasis in the Malaria Parasite Plasmodium falciparum | 002 | 1 | NIH | 1/16/2025 | $0 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | K08DK142012 | Calcium-mediated paracrine signaling in beta cell cilia | 000 | 1 | NIH | 2/28/2025 | $153,266 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | UG1CA233339 | Washington University/Siteman Cancer Center Lead Academic Site | 000 | 6 | NIH | 3/7/2025 | $784,233 |
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