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 | Issue Date FY: 2025 ( Subtotal = $723,654,798 ) (Continued on the next page) |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R50CA305824 | Advancing Precision Oncology with Scalable Software Solutions for Clinical Variant Interpretation and Expert Curation | 000 | 1 | NIH | 8/29/2025 | $155,500 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | K99AG090693 | Epigenetic modulations by sleep to mitigate neurodegeneration | 000 | 1 | NIH | 9/15/2025 | $125,000 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R03DK144351 | Role of Ppm1k in Macrophage Activation and Metabolic Disease | 000 | 1 | NIH | 9/4/2025 | $233,250 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R21AR086404 | Validation of the Pathomechanics and Biology of a Novel Pre-Clinical Rabbit Model for Hip Pre-Osteoarthritis | 000 | 1 | NIH | 9/10/2025 | $378,228 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | F30DK143705 | Primary Cilia Regulate GLP-1 Signaling in Pancreatic Islets | 001 | 1 | NIH | 9/3/2025 | $0 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R56HD096737 | Quantitative and computational characterization of oxytocin receptor function | 000 | 6 | NIH | 8/29/2025 | $999,593 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R21EY038987 | Scaling Strategies to Assess Pathogenicity of Variants of Uncertain Significance | 000 | 1 | NIH | 9/11/2025 | $427,625 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | F30DK143705 | Primary Cilia Regulate GLP-1 Signaling in Pancreatic Islets | 000 | 1 | NIH | 9/3/2025 | $36,046 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | K08AR086318 | The Role of Alternative Splicing in FSHD Disease Models | 000 | 1 | NIH | 8/29/2025 | $175,500 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01HL180913 | PET imaging of Chemotherapy-Induced Cardiotoxicity | 000 | 1 | NIH | 9/12/2025 | $768,567 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R33AG078799 | AI models of multi-omic data integration for ming longevity core signaling pathways | 000 | 2 | NIH | 8/29/2025 | $1,533,939 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01GM160854 | RNA damage induced DNA breaks: A new mechanism of genome instability | 000 | 1 | NIH | 9/3/2025 | $854,927 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | K99DK142010 | Identifying Early Signs of Foot Complications in Childhood-onset Type 2 Diabetes Mellitus | 000 | 1 | NIH | 9/2/2025 | $91,500 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | K01DK144664 | Cytoskeletal regulation of gut tube organogenesis and subsequent maturation of stem cell-derived islets | 000 | 1 | NIH | 9/11/2025 | $138,753 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | F30DK142304 | Identifying Prevotella copri-mediated effects of dietary glycan supplementation on microbial community and host metabolism | 000 | 1 | NIH | 9/5/2025 | $36,046 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01CA303538 | Natural killer cells subvert immune checkpoint therapy of tumors | 000 | 1 | NIH | 9/22/2025 | $3,182,665 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01AR085149 | Intra-articular corticosteroid injections for symptomatic osteoarthritis: The effects of injection dose, frequency, and timing on safety | 000 | 1 | NIH | 9/10/2025 | $2,017,972 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01DK144476 | Cellular Senescence and the AKI to CKD transition | 000 | 1 | NIH | 9/5/2025 | $1,491,303 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | UG3CA305777 | Implementation science to scale and sustain tobacco treatment leveraging point of care paradigm and health information technology | 000 | 1 | NIH | 9/5/2025 | $1,594,797 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01HD119277 | Modeling Human Trophoblast Differentiation and Function Using Pluripotent Stem Cells | 000 | 1 | NIH | 8/29/2025 | $657,377 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01DK142751 | Commensal fungi promote wound repair by modulating host metabolites | 000 | 1 | NIH | 9/8/2025 | $465,444 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | UH3CA272904 | Whole Genome Sequencing for Genomic Evaluation and Risk Stratification of Patients with Myelodysplastic Syndromes | 000 | 2 | NIH | 9/10/2025 | $388,750 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | F31MH139184 | Quantifying Psychological Resilience and Susceptibility to Predict Childhood Outcomes | 001 | 1 | NIH | 9/11/2025 | $0 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R00EY032171 | Signaling networks and transcriptional programs in lens vesicle formation | 000 | 3 | NIH | 9/9/2025 | $249,000 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R56DK139218 | Early myeloid lineage specification mechanisms at the top of the hematopoietic hierarchy | 000 | 1 | NIH | 9/11/2025 | $86,856 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | F31MH139184 | Quantifying Psychological Resilience and Susceptibility to Predict Childhood Outcomes | 000 | 1 | NIH | 9/11/2025 | $36,673 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | K01MD020519 | A Precision Medicine Approach to Fetal Growth Restriction Among Black Women | 000 | 1 | NIH | 9/5/2025 | $134,404 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01CA266041 | Understanding the role of DNA damage repair in racial disparities of triple-negative breast cancer outcomes | 000 | 4 | NIH | 3/7/2025 | $409,560 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01CA266041 | Understanding the role of DNA damage repair in racial disparities of triple-negative breast cancer outcomes | 001 | 4 | NIH | 5/23/2025 | $45,506 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | K08NS117888 | Role of Axonal Sprouting Mediated Network Reorganization in Stroke Recovery | 000 | 4 | NIH | 3/12/2025 | $198,676 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01HG014139 | High-throughput interrogation of long-range enhancers | 000 | 1 | NIH | 8/13/2025 | $2,796,648 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R35GM158294 | The role of the ribosome and translation factors in mediating stress signaling | 000 | 1 | NIH | 8/14/2025 | $2,777,852 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | K99AI193238 | Investigating the role of T cells in promoting post-acute memory deficits after COVID-19 in mice | 000 | 1 | NIH | 7/7/2025 | $107,995 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | U24CA305456 | Accelerating the expert-crowdsourcing of cancer variant interpretation in CIViC | 001 | 1 | NIH | 9/3/2025 | $0 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | U24CA305456 | Accelerating the expert-crowdsourcing of cancer variant interpretation in CIViC | 000 | 1 | NIH | 8/29/2025 | $809,106 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01HD119966 | Preclinical Testing of Early Life Anti-Myostatin Therapy for Osteogenesis | 000 | 1 | NIH | 8/14/2025 | $652,723 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | K01DA062777 | Investigation into nTS mu opioid receptor mechanisms contributing to fentanyl-induced cardiorespiratory depression | 000 | 1 | NIH | 8/19/2025 | $15,196 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01MH132504 | Investigating non-canonical mechanisms of endogenous opioids on motivation in dorsal midbrain | 000 | 3 | NIH | 3/12/2025 | $445,276 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | K01DA062777 | Investigation into nTS mu opioid receptor mechanisms contributing to fentanyl-induced cardiorespiratory depression | 000 | 1 | NIH | 8/19/2025 | $495,950 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | U01DE034565 | Validation of a clinically accessible prognostic biomarker for oropharynx cancer using molecular and spatial data | 005 | 1 | NIH | 9/8/2025 | $0 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | U01DE034565 | Validation of a clinically accessible prognostic biomarker for oropharynx cancer using molecular and spatial data | 003 | 1 | NIH | 8/6/2025 | $28,988 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R01MH132504 | Investigating non-canonical mechanisms of endogenous opioids on motivation in dorsal midbrain | 001 | 3 | NIH | 9/18/2025 | $78,579 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | U01DE034565 | Validation of a clinically accessible prognostic biomarker for oropharynx cancer using molecular and spatial data | 004 | 1 | NIH | 8/15/2025 | $32,872 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | U01DE034565 | Validation of a clinically accessible prognostic biomarker for oropharynx cancer using molecular and spatial data | 002 | 1 | NIH | 8/5/2025 | $75,000 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | U01DE034565 | Validation of a clinically accessible prognostic biomarker for oropharynx cancer using molecular and spatial data | 001 | 1 | NIH | 8/5/2025 | -$136,860 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | U01DE034565 | Validation of a clinically accessible prognostic biomarker for oropharynx cancer using molecular and spatial data | 000 | 1 | NIH | 3/12/2025 | $638,903 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R21EY037063 | Hyperoxia and enhancing efferocytosis in the eye | 001 | 1 | NIH | 9/26/2025 | $0 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R21EY037063 | Hyperoxia and enhancing efferocytosis in the eye | 000 | 1 | NIH | 8/15/2025 | $427,625 |
| | 2025 | 2025 | WASHINGTON UNIVERSITY, THE | 1 BROOKINGS DR | SAINT LOUIS | MO | 63130-4862 | SAINT LOUIS | USA | R21HD115568 | Peripheral and central mechanisms of endometriosis pain | 000 | 1 | NIH | 3/13/2025 | $233,250 |
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