Tuesday, January 6, 2026 1/6/2026

Upper Midwest StrokeNet Regional Coordinating Center (RCC)

Award Number: U24NS107269
ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/15/2018
PERIOD OF PERFORMANCE END DATE: 11/30/2028

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Upper Midwest StrokeNet Regional Coordinating Center (RCC) - Project Summary The Upper Midwest Regional Coordinating Center (RCC), previously the University of Minnesota (UMN) RCC, is an established, high-performance RCC within Stroke Net. The pillars of the Upper Midwest Stroke Net RCC are: 1) unparalleled expertise in clinical trial conduct with a track record of high enrollment, most notably in complex time-sensitive acute stroke trials, 2) close collaboration with robust stroke care systems in the upper Midwest led by our colleagues and former trainees, and 3) direct integration with physician-scientist training programs. The Upper Midwest RCC comprises 12 sites with large urban and rural catchment areas throughout Minnesota and neighboring states. Our leadership is uniquely qualified, complementary, and aligned with Stroke Net aims. Dr. Streib (PI), the Cerebrovascular Director at M Health-Fairview (MHFV), developed a centralized internal stroke research network across MHFV hospitals. Within this network we are driving clinical research innovation: ~50% of our acute stroke trial participants are enrolled utilizing “remote research” in which the subject is not physically in the same location as the clinical and research teams. Remote research expands access to clinical trials more equitably thereby reaching diverse, underrepresented populations in clinical trials. Dr. Lakshminarayan (PI, Career Enhancement Director) directs the Clinical Research Training Program in the nationally-ranked UMN School of Public Health. She is an NIH-funded investigator whose research deliberately involves low-resource health systems, including federally qualified health centers, in order to ensure recruitment of under-represented minorities. Ms. Staugaitis' accumulated experience as project manager for Stroke Net, Strategies to Innovate Emergency Care Clinical Trials Network (SIREN), and essential multicenter COVID trials has been critical to operationalizing practical, efficient, and effective clinical research workflows. M-Health Fairview sites are top enrollers in multiple StrokeNet (MOST, ARCADIA, and CAPTIVA), NIH (PRECISE), and industry stroke trials (TIMELESS). Study aims are: 1) Continue as a leading RCC within StrokeNet through sustained high-volume recruitment and support and mentorship of our satellite sites. 2) Further study, develop, and implement standardized remote research capability throughout MHFV and StrokeNet in order to increase equitable access to clinical trials, promote diversity, and improve the generalizability of StrokeNet clinical trial results. 3) Leverage the resources of the UMN CTSI and School of Public Health and the StrokeNet to mentor exceptional physician scientists who will develop and conduct future stroke trials. In the next grant cycle, our RCC will remain a vital contributor to StrokeNet through continued high-volume recruitment, the further development, modernization and dissemination of best-practice clinical trial workflows, and strong commitment to educating the next generation of talented stroke physician-scientists.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $372,117 )
2026	2026	REGENTS OF THE UNIVERSITY OF MINNESOTA	2221 UNIVERSITY AVE SE STE 100	MINNEAPOLIS	MN	55414	HENNEPIN	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	8	12/16/2025	NON-COMPETING CONTINUATION	$372,117
														Subtotal = $372,117

Issue Date FY: 2025 ( Subtotal = $372,117 )
2025	2025	REGENTS OF THE UNIVERSITY OF MINNESOTA	200 OAK ST SE	MINNEAPOLIS	MN	55455	HENNEPIN	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	002	7	11/29/2024	NON-COMPETING CONTINUATION	$372,117
2025	2024	REGENTS OF THE UNIVERSITY OF MINNESOTA	200 OAK ST SE	MINNEAPOLIS	MN	55455	HENNEPIN	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	6	11/8/2024	COMPETING CONTINUATION	$1
2025	2023	REGENTS OF THE UNIVERSITY OF MINNESOTA	200 OAK ST SE	MINNEAPOLIS	MN	55455	HENNEPIN	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	5	11/8/2024	SUPPLEMENT FOR EXPANSION	-$1
														Subtotal = $372,117

Issue Date FY: 2024 ( Subtotal = $413,463 )
2024	2024	REGENTS OF THE UNIVERSITY OF MINNESOTA	200 OAK ST SE	MINNEAPOLIS	MN	55455	HENNEPIN	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	002	6	12/5/2023	COMPETING CONTINUATION	$413,463
2024	2023	REGENTS OF THE UNIVERSITY OF MINNESOTA	200 OAK ST SE	MINNEAPOLIS	MN	55455	HENNEPIN	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	5	12/1/2023	SUPPLEMENT FOR EXPANSION	$0
2024	2022	REGENTS OF THE UNIVERSITY OF MINNESOTA	200 OAK ST SE	MINNEAPOLIS	MN	55455	HENNEPIN	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	5	12/1/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $413,463

Issue Date FY: 2023 ( Subtotal = $103,332 )
2023	2023	REGENTS OF THE UNIVERSITY OF MINNESOTA	200 OAK ST SE	MINNEAPOLIS	MN	55455	HENNEPIN	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	5	7/7/2023	SUPPLEMENT FOR EXPANSION	$103,332
														Subtotal = $103,332

Issue Date FY: 2022 ( Subtotal = $308,000 )
2022	2022	REGENTS OF THE UNIVERSITY OF MINNESOTA	200 OAK ST SE # 224	MINNEAPOLIS	MN	55455	HENNEPIN	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	5	8/1/2022	NON-COMPETING CONTINUATION	$308,000
2022	2021	REGENTS OF THE UNIVERSITY OF MINNESOTA	200 OAK ST SE # 224	MINNEAPOLIS	MN	55455	HENNEPIN	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	4	8/24/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $308,000

Issue Date FY: 2021 ( Subtotal = $308,000 )
2021	2021	REGENTS OF THE UNIVERSITY OF MINNESOTA	200 OAK ST SE # 224	MINNEAPOLIS	MN	55455	HENNEPIN	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	4	8/19/2021	NON-COMPETING CONTINUATION	$308,000
2021	2019	REGENTS OF THE UNIVERSITY OF MINNESOTA	200 OAK ST SE # 224	MINNEAPOLIS	MN	55455	HENNEPIN	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	2	8/16/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $308,000

Issue Date FY: 2020 ( Subtotal = $308,000 )
2020	2020	REGENTS OF THE UNIVERSITY OF MINNESOTA	200 OAK ST SE # 224	MINNEAPOLIS	MN	55455	HENNEPIN	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	3	8/4/2020	NON-COMPETING CONTINUATION	$308,000
2020	2019	REGENTS OF THE UNIVERSITY OF MINNESOTA	200 OAK ST SE # 224	MINNEAPOLIS	MN	55455	HENNEPIN	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	2	12/6/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $308,000

Issue Date FY: 2019 ( Subtotal = $330,290 )
2019	2019	REGENTS OF THE UNIVERSITY OF MINNESOTA	200 OAK ST SE # 224	MINNEAPOLIS	MN	55455	HENNEPIN	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	002	2	8/9/2019	NON-COMPETING CONTINUATION	$308,000
2019	2018	REGENTS OF THE UNIVERSITY OF MINNESOTA	200 OAK ST SE # 224	MINNEAPOLIS	MN	55455	HENNEPIN	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	1	3/26/2019	NEW	$0
2019	2018	REGENTS OF THE UNIVERSITY OF MINNESOTA	200 OAK ST SE # 224	MINNEAPOLIS	MN	55455	HENNEPIN	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	1	12/13/2018	NEW	$22,290
														Subtotal = $330,290

Issue Date FY: 2018 ( Subtotal = $308,000 )
2018	2018	REGENTS OF THE UNIVERSITY OF MINNESOTA	200 OAK ST SE # 224	MINNEAPOLIS	MN	55455	HENNEPIN	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	1	8/3/2018	NEW	$308,000
														Subtotal = $308,000

Grand Total All Awards = $2,823,319

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Upper Midwest StrokeNet Regional Coordinating Center (RCC)

Award Number: U24NS107269

ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/15/2018

PERIOD OF PERFORMANCE END DATE: 11/30/2028

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