Monday, June 30, 2025 6/30/2025

Sickle Pan-African Research Consortium Clinical Coordinating Center (SPARCO Center)

Award Number: U24HL135881
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 04/01/2017
PERIOD OF PERFORMANCE END DATE: 04/30/2026

Group Awards By:

View Award Description

Sickle Pan-African Research Consortium Clinical Coordinating Center (SPARCO Center) - Project Summary/Abstract Sickle Cell Disease (SCD) is a disorder of public health significance; common [300,000 global annual births, over 75% in Sub-Saharan Africa (SSA)], with a high burden of morbidity and mortality despite evidence based, effective interventions. Background: Sickle Pan-African Research Consortium (SPARCO) consisting of a hub in Tanzania and sub-award sites in three countries (Tanzania, Nigeria and Ghana) and the Sickle Africa Data Coordinating Center (SADACC) formed a SCD in Sub-Saharan Africa (SSA) Network. This successfully developed a registry and enrolled over 10,000 SCD patients; developed recommended standards of care for SCD management and facilitate skills development in clinicians, researchers and educators. A strategy for multi- site research was developed. The proposed phase: will entail growth of SPARCO from one entity into four entities, with SPARCO hub functioning as the clinical coordinating center (SPARCO Center) and the 3 sub- awards becoming autonomous SPARCO sites, with addition of three more sites in Africa. Unique features and innovation: Encouraging autonomy, whilst allowing sites to adapt activities to their settings whilst at the same retain network cohesiveness, allowing knowledge exchange. Furthermore, the integration of health, research and education is critical in areas with limited resources. Specific aims and approach: SPARCO Center will be responsible for facilitating and coordinating activities in SPARCO sites, enabling exchange of expertise and experience, sharing of resources and harmonize in order to implement SCD-related activities. SPARCO Center has six specific aims, to i) provide governance, oversight and operations for coordination of collaborative sites, by establishing a framework and procedures which will allow integration of new sites whilst strengthening the existing sites ii) expand the SCD registry database by enrolling 21,000 new participants to give a total of 34,000 participants and collect follow up data. In collaboration with SADaCC, SPARCO center will continue to refine database elements and harmonize SCD phenotype definitions. iii) support integration of consistent Standards of Care into SCD healthcare through dialogue with institutional, national, regional and global health authorities, Ministries of Health, public and private healthcare programs. iv) facilitate launching and successful completion of cohort and implementation research studies v) support participation in training programs by strengthening and developing partnerships with existing institutional, national, regional and international educational/training programs and vi) facilitate engagement with public and private partners at different levels across the globe, including sickle cell communities, public and private organizations in health, research and education. Expected application of results: To reduce the public health burden of SCD by establishing framework for research generating locally-appropriate evidence to address factors limiting successful implementation of interventions. SPARCO center will facilitate provision of comprehensive healthcare to increase survival and quality of life, whilst making a contribution to global scientific knowledge, enabling disease-modifying and curative treatment for SCD.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $506,215 )
2024	2024	MUHIMBILI UNIVERSITY OF HEALTH AND ALLIED SCIENCES	UNITED NATIONS ROAD	DAR ES SALAAM				TZA	Blood Diseases and Resources Research	000	8	5/20/2024	NON-COMPETING CONTINUATION	$506,215
														Subtotal = $506,215

Issue Date FY: 2023 ( Subtotal = $554,510 )
2023	2023	MUHIMBILI UNIVERSITY OF HEALTH AND ALLIED SCIENCES	UNITED NATIONS ROAD	DAR ES SALAAM				TZA	Blood Diseases and Resources Research	001	7	8/7/2023	NON-COMPETING CONTINUATION	$554,510
2023	2020	MUHIMBILI UNIVERSITY OF HEALTH AND ALLIED SCIENCES	UNITED NATIONS ROAD	DAR ES SALAAM				TZA	Blood Diseases and Resources Research	000	4	3/23/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $554,510

Issue Date FY: 2022 ( Subtotal = $648,358 )
2022	2022	MUHIMBILI UNIVERSITY OF HEALT H AND ALLIED SCIENCES	UNITED NATIONS ROAD	DAR ES SALAAM	NULL			TZA	Blood Diseases and Resources Research	000	6	6/13/2022	NON-COMPETING CONTINUATION	$648,358
														Subtotal = $648,358

Issue Date FY: 2021 ( Subtotal = $546,549 )
2021	2021	MUHIMBILI UNIVERSITY OF HEALT H AND ALLIED SCIENCES	UNITED NATIONS ROAD	DAR ES SALAAM	NULL			TZA	Blood Diseases and Resources Research	003	5	8/22/2021	COMPETING CONTINUATION	$71,023
2021	2021	MUHIMBILI UNIVERSITY OF HEALT H AND ALLIED SCIENCES	UNITED NATIONS ROAD	DAR ES SALAAM				TZA	Blood Diseases and Resources Research	001	5	4/30/2021	COMPETING CONTINUATION	$546,549
2021	2020	MUHIMBILI UNIVERSITY OF HEALT H AND ALLIED SCIENCES	UNITED NATIONS ROAD	DAR ES SALAAM	NULL			TZA	Blood Diseases and Resources Research	002	4	8/22/2021	NON-COMPETING CONTINUATION	-$71,023
2021	2020	MUHIMBILI UNIVERSITY OF HEALT H AND ALLIED SCIENCES	UNITED NATIONS ROAD	DAR ES SALAAM				TZA	Blood Diseases and Resources Research	000	4	4/26/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $546,549

Issue Date FY: 2020 ( Subtotal = $683,332 )
2020	2020	MUHIMBILI UNIVERSITY OF HEALT H AND ALLIED SCIENCES	UNITED NATIONS ROAD	DAR ES SALAAM				TZA	Blood Diseases and Resources Research	001	4	4/22/2020	NON-COMPETING CONTINUATION	$683,332
2020	2018	MUHIMBILI UNIVERSITY OF HEALT H AND ALLIED SCIENCES	UNITED NATIONS ROAD	DAR ES SALAAM				TZA	Blood Diseases and Resources Research	000	2	2/12/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $683,332

Issue Date FY: 2019 ( Subtotal = $680,765 )
2019	2019	MUHIMBILI UNIVERSITY OF HEALT H AND ALLIED SCIENCES	UNITED NATIONS ROAD	DAR ES SALAAM				TZA	Blood Diseases and Resources Research	001	3	9/20/2019	SUPPLEMENT FOR EXPANSION	$169,955
2019	2019	MUHIMBILI UNIVERSITY OF HEALT H AND ALLIED SCIENCES	UNITED NATIONS ROAD	DAR ES SALAAM				TZA	Blood Diseases and Resources Research	000	3	4/19/2019	NON-COMPETING CONTINUATION	$510,810
														Subtotal = $680,765

Issue Date FY: 2018 ( Subtotal = $511,938 )
2018	2018	MUHIMBILI UNIVERSITY OF HEALT H AND ALLIED SCIENCES	UNITED NATIONS ROAD	DAR ES SALAAM				TZA	Blood Diseases and Resources Research	000	2	5/25/2018	NON-COMPETING CONTINUATION	$511,938
														Subtotal = $511,938

Issue Date FY: 2017 ( Subtotal = $634,807 )
2017	2017	MUHIMBILI UNIVERSITY OF HEALT H AND ALLIED SCIENCES	UNITED NATIONS ROAD	DAR ES SALAAM				TZA	Blood Diseases and Resources Research	000	1	3/31/2017	NEW	$634,807
														Subtotal = $634,807

Grand Total All Awards = $4,766,474

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Sickle Pan-African Research Consortium Clinical Coordinating Center (SPARCO Center)

Award Number: U24HL135881

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 04/01/2017

PERIOD OF PERFORMANCE END DATE: 04/30/2026

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer