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National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA): Administrative Resource

Award Number: U24AA021695
ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA): Administrative Resource - PROJECT SUMMARY Initiating excessive alcohol drinking during adolescence is known to disturb typical neurodevelopment, increase the risk of alcohol use disorder (AUD), and accelerate involutional processes in adulthood. This application proposes examination of socioeconomic status (SES) and racial/ethnic differences in the Recovery specialty project of the National Consortium on Alcohol and Neurodevelopment in Adolescence - Adulthood (NCANDA- A). The Recovery Project at the Duke, OHSU, and UCSD Research Sites examines the extent to which short- term (i.e., 4 weeks) alcohol use discontinuation results in acute improvement in cognition, affect, sleep and resting heart rate, and reversal of the adverse structural and functional brain effects of frequent binge alcohol use. For this application, we will extend analyses planned in the parent grant with supplemental analyses of patterns and predictors of abstinence and changes in behavior for adolescents and young adults participating in the four-week abstinence protocol who identify as from diverse socioeconomic and minoritized ethnic/radial backgrounds. We will test the hypothesis that predictors of recovery after 4 weeks of discontinuation of alcohol consumption, and predictors of improvements in behavior and affect during this time, will differ by SES and ethnic/racial group. The study has two specific aims. Aim 1 will investigate how four weeks of abstinence influence mental health (depression and anxiety), physical activity level, social interaction, and self-reported sleep as a function of socioeconomic indicators and racial/ethnic group. Aim 2 will examine cultural, community, and context predictors of abstinence and improvements by SES and racial/ethnic group. Analyses within the Recovery Project will serve as pilot research to assist the candidate in understanding the social determinants of these aspects of health. A “Research Independence Plan” is proposed to shape the candidate’s future goals and professional development during the training period through weekly meetings with Dr. Sandra Brown, guided readings, and supervised writing, data analysis and scientific dissemination. The trainee will work with the NCANDA research team at UC San Diego to learn the Recovery protocol, attend biweekly seminars on substance use research with adolescents, and receive professional development mentorship with Dr. Brown in weekly meetings, including the responsible conduct of research.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $623,268 )
2024	2024	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	000	13	6/11/2024	NON-COMPETING CONTINUATION	$524,097
2024	2024	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	001	13	9/6/2024	SUPPLEMENT FOR EXPANSION	$99,171
														Subtotal = $623,268

Issue Date FY: 2023 ( Subtotal = $585,878 )
2023	2023	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	004	12	9/4/2023	SUPPLEMENT FOR EXPANSION	$39,500
2023	2023	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	003	12	6/28/2023	NON-COMPETING CONTINUATION	$546,378
2023	2022	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	002	11	5/8/2023	COMPETING CONTINUATION	$255,305
2023	2022	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	000	11	1/25/2023	COMPETING CONTINUATION	$0
2023	2021	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	001	10	5/8/2023	NON-COMPETING CONTINUATION	-$255,305
														Subtotal = $585,878

Issue Date FY: 2022 ( Subtotal = $562,769 )
2022	2022	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	000	11	8/5/2022	COMPETING CONTINUATION	$562,769
														Subtotal = $562,769

Issue Date FY: 2021 ( Subtotal = $474,861 )
2021	2021	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	000	10	6/15/2021	NON-COMPETING CONTINUATION	$474,861
														Subtotal = $474,861

Issue Date FY: 2020 ( Subtotal = $536,323 )
2020	2020	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	002	9	9/21/2020	SUPPLEMENT FOR EXPANSION	$0
2020	2020	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	000	9	6/9/2020	NON-COMPETING CONTINUATION	$486,486
2020	2020	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	001	9	7/30/2020	SUPPLEMENT FOR EXPANSION	$49,837
														Subtotal = $536,323

Issue Date FY: 2019 ( Subtotal = $548,452 )
2019	2019	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	002	8	6/19/2019	NON-COMPETING CONTINUATION	$489,882
2019	2019	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	004	8	8/7/2019	SUPPLEMENT FOR EXPANSION	$0
2019	2019	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	003	8	8/6/2019	SUPPLEMENT FOR EXPANSION	$58,570
2019	2018	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	001	7	3/4/2019	NON-COMPETING CONTINUATION	$0
2019	2018	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	000	7	10/24/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $548,452

Issue Date FY: 2018 ( Subtotal = $634,953 )
2018	2018	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	002	7	6/27/2018	NON-COMPETING CONTINUATION	$497,840
2018	2018	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	003	7	7/25/2018	SUPPLEMENT FOR EXPANSION	$137,113
2018	2017	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	001	6	12/14/2017	COMPETING CONTINUATION	$231,502
2018	2017	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	005	6	9/17/2018	COMPETING CONTINUATION	$1,909
2018	2016	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	004	5	9/17/2018	EXTENSION WITH OR WITHOUT FUNDS	-$1,909
2018	2016	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	000	5	12/14/2017	EXTENSION WITH OR WITHOUT FUNDS	-$231,502
														Subtotal = $634,953

Issue Date FY: 2017 ( Subtotal = $673,453 )
2017	2017	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	000	6	7/4/2017	COMPETING CONTINUATION	$541,801
2017	2016	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	001	5	9/18/2017	EXTENSION WITH OR WITHOUT FUNDS	$131,652
														Subtotal = $673,453

Issue Date FY: 2016 ( Subtotal = $505,722 )
2016	2016	UNIVERSITY OF CALIFORNIA-SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	000	5	6/24/2016	EXTENSION WITH OR WITHOUT FUNDS	$505,722
2016	2016	UNIVERSITY OF CALIFORNIA-SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Alcohol Research Programs	001	5	7/27/2016	EXTENSION WITH OR WITHOUT FUNDS	$0
														Subtotal = $505,722

Grand Total All Awards = $5,145,679

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National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA): Administrative Resource

Award Number: U24AA021695

ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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