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Enhancing the whole genome sequence(WGS)based surveillance of Salmonella, Listeria and Shiga Toxin producing Escherichia coli(STEC) isolated from food and environment at the national and global level

Award Number: U18FD006194
ORGANIZATION: FOOD AND DRUG ADMINISTRATION
OPDIV: FDA
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: KDA (KNOWLEDGE/DEVELOPMENT/APPLICATION)

Group Awards By Issue Date FY or Funding FY:

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Salmonella, Listeria and STEC isolated from retail meat, fresh produce and their environment have been implicated as the leading causes of bacterial foodborne illness in the US and around the world. It is important that we monitor the prevalence and trends of important foodborne bacterial strains in food products that can eventually pass to the consumers along the farm-to-fork chain resulting in significant public health impact. It is, therefore, important to expand the current surveillance network and monitor these important pathogens at the global scale to prevent future outbreaks. We propose to do this in collaboration with the WHO-AGISAR (Advisory Committee on Integrated Surveillance of Antimicrobial Resistance) which funds countries to conduct surveillance of antimicrobial resistant foodborne bacterial pathogens in humans, food products and the environment. We strongly believe that the data generated through the proposed work will assist in monitoring Salmonella, Listeria and STEC from at the international level where current surveillance systems are not robust enough to track them. The WGS data and metadata will significantly improve the power to resolve outbreaks by helping to quickly link clinical and retail product samples and assist in outbreak investigations. The PD (Dr. Thakur) laboratory, in partnership with the NC Department of Agriculture and Consumer Services (NCDACS), is a GenomeTrakr collaborating laboratory. Our proposal will significantly assist us in tracking emergence of potential new Salmonella, Listeria and STEC strains and allow the public health agencies to take appropriate steps to safeguard human and animal health at the global level. The specific objectives of our proposal are: 1) Establish a robust surveillance system based on whole genome sequence (WGS) profile of 400 Salmonella, Listeria and STEC isolated from food and environmental sources within and outside the US. 2) Compare the WGS profiles of Salmonella, Listeria and STEC at the global scale to assist in outbreak investigations and track emerging strains of public health importance. The long-term objective of our proposal is to protect and promote public health by strengthening the surveillance of Salmonella, Listeria and STEC within and outside the US by generating critical WGS data and contributing to the GenomeTrakr mission.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2023 ( Subtotal = -$39 )
2023	2018	NORTH CAROLINA STATE UNIVERSITY	2601 WOLF VILLAGE WAY	RALEIGH	NC	27607	WAKE	USA	Food and Drug Administration Research	000	2	12/5/2022	NON-COMPETING CONTINUATION	-$39
														Subtotal = -$39

Issue Date FY: 2019 ( Subtotal = $0 )
2019	2018	NORTH CAROLINA STATE UNIVERSITY	2701 SULLIVAN DR STE 240	RALEIGH	NC	27695	WAKE	USA	Food and Drug Administration Research	000	2	12/14/2018	NON-COMPETING CONTINUATION	$0
2019	2018	NORTH CAROLINA STATE UNIVERSITY	2701 SULLIVAN DR STE 240	RALEIGH	NC	27695	WAKE	USA	Food and Drug Administration Research	001	2	7/10/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2018 ( Subtotal = $164,998 )
2018	2018	NORTH CAROLINA STATE UNIVERSITY	2701 SULLIVAN DR STE 240	RALEIGH	NC	27695	WAKE	USA	Food and Drug Administration Research	000	2	6/12/2018	NON-COMPETING CONTINUATION	$164,998
														Subtotal = $164,998

Issue Date FY: 2017 ( Subtotal = $164,998 )
2017	2017	NORTH CAROLINA STATE UNIVERSITY	2701 SULLIVAN DR STE 240 CAMPUS BX 7514	RALEIGH	NC	27695	WAKE	USA	Food and Drug Administration Research	000	1	8/31/2017	NEW	$164,998
2017	2017	NORTH CAROLINA STATE UNIVERSITY	2701 SULLIVAN DR STE 240 CAMPUS BX 7514	RALEIGH	NC	27695	WAKE	USA	Food and Drug Administration Research	001	1	9/19/2017	NEW	$0
														Subtotal = $164,998

Grand Total All Awards = $329,957

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Enhancing the whole genome sequence(WGS)based surveillance of Salmonella, Listeria and Shiga Toxin producing Escherichia coli(STEC) isolated from food and environment at the national and global level

Award Number: U18FD006194

ORGANIZATION: FOOD AND DRUG ADMINISTRATION

OPDIV: FDA

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: KDA (KNOWLEDGE/DEVELOPMENT/APPLICATION)

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