Wednesday, April 2, 2025 4/2/2025

ECOG-ACRIN Network Group Statistics and Data Management Center

Award Number: U10CA180794
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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ECOG-ACRIN Network Group Statistics and Data Management Center - This grant will provide support for the Statistics and Data Management Center (SDMC) of the ECOG- ACRIN Cancer Research Group. The SDMC is organized and operated jointly by the Department of Biostatistics and Computational Biology at the Dana-Farber Cancer Institute (DFCI), the Department of Biostatistics at Brown University, the ECOG-ACRIN Medical Research Foundation (EAMRF), and the American College of Radiology (ACR), under the direction of the Group Statisticians. The primary responsibility for data collection and management belongs to the Data Management Center, consisting of EAMRF and ACR. The primary responsibility for study design, monitoring, and analysis, and for overseeing and coordinating SDMC operations, belongs to the Biostatistics Center, consisting of DFCI and Brown University. The primary contact site for grant administration is DFCI. ECOG-ACRIN is a multi-modality group conducting a wide range of studies, including definitive phase III trials of therapeutic interventions, earlier phase studies developing new therapies, studies focused on diagnosis and of advanced imaging methods, investigation of laboratory and imaging based biomarkers, and studies incorporating patient reported outcomes. The SDMC is responsible for all quantitative aspects of EA’s activities. Our overall goals are to conduct clinical trials to the highest standards in statistical methods, data management, and regulatory compliance, while continually improving efficiency of all of our processes and systems to optimize the use of our limited resources. Areas of particular focus in this grant include studies incorporating tissue and imaging biomarkers to direct therapy, studies of immunotherapy, studies of de-intensification of therapy to reduce morbidity, studies investigating novel biomarkers, and studies investigating the relationship of biomarkers and therapy in populations defined by race, ethnicity, gender, and age.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $4,683,890 )
2025	2025	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Cancer Treatment Research	000	11	2/28/2025	SUPPLEMENT FOR EXPANSION	$4,683,890
														Subtotal = $4,683,890

Issue Date FY: 2024 ( Subtotal = $7,906,229 )
2024	2024	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Cancer Treatment Research	001	11	2/27/2024	NON-COMPETING CONTINUATION	$6,896,646
2024	2024	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Cancer Treatment Research	003	11	9/6/2024	NON-COMPETING CONTINUATION	$619,260
2024	2024	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Cancer Treatment Research	004	11	9/26/2024	NON-COMPETING CONTINUATION	$0
2024	2024	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Cancer Treatment Research	002	11	4/26/2024	NON-COMPETING CONTINUATION	$390,323
2024	2023	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Cancer Treatment Research	000	10	2/23/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $7,906,229

Issue Date FY: 2023 ( Subtotal = $7,724,706 )
2023	2023	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	001	10	4/11/2023	NON-COMPETING CONTINUATION	$300,000
2023	2023	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	000	10	2/28/2023	NON-COMPETING CONTINUATION	$7,266,451
2023	2023	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Cancer Treatment Research	002	10	9/7/2023	NON-COMPETING CONTINUATION	$158,255
														Subtotal = $7,724,706

Issue Date FY: 2022 ( Subtotal = $8,149,308 )
2022	2022	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	001	9	8/23/2022	NON-COMPETING CONTINUATION	$807,699
2022	2022	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	002	9	9/21/2022	NON-COMPETING CONTINUATION	$0
2022	2022	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	000	9	3/3/2022	NON-COMPETING CONTINUATION	$7,341,609
														Subtotal = $8,149,308

Issue Date FY: 2021 ( Subtotal = $8,612,042 )
2021	2021	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	002	8	3/2/2021	NON-COMPETING CONTINUATION	$0
2021	2021	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	003	8	9/14/2021	NON-COMPETING CONTINUATION	$1,322,255
2021	2021	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	001	8	2/24/2021	NON-COMPETING CONTINUATION	$7,289,787
2021	2020	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	000	7	10/30/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $8,612,042

Issue Date FY: 2020 ( Subtotal = $9,053,875 )
2020	2020	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	001	7	9/8/2020	NON-COMPETING CONTINUATION	$1,327,463
2020	2020	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	000	7	2/28/2020	NON-COMPETING CONTINUATION	$7,726,412
														Subtotal = $9,053,875

Issue Date FY: 2019 ( Subtotal = $9,148,818 )
2019	2019	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	000	6	4/4/2019	COMPETING CONTINUATION	$7,870,599
2019	2019	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	003	6	9/16/2019	COMPETING CONTINUATION	$1,278,219
2019	2019	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	002	6	6/24/2019	COMPETING CONTINUATION	$81,303
2019	2018	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	001	5	6/24/2019	NON-COMPETING CONTINUATION	-$81,303
														Subtotal = $9,148,818

Issue Date FY: 2018 ( Subtotal = $7,856,253 )
2018	2018	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	001	5	9/17/2018	NON-COMPETING CONTINUATION	$723,052
2018	2018	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	000	5	2/20/2018	NON-COMPETING CONTINUATION	$7,133,201
														Subtotal = $7,856,253

Issue Date FY: 2017 ( Subtotal = $7,182,126 )
2017	2017	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	001	4	6/30/2017	NON-COMPETING CONTINUATION	$260,946
2017	2017	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	000	4	3/6/2017	NON-COMPETING CONTINUATION	$6,921,180
														Subtotal = $7,182,126

Issue Date FY: 2016 ( Subtotal = $6,920,200 )
2016	2016	DANA-FARBER CANCER INSTITUTE	44 BINNEY STREET	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	000	3	3/23/2016	NON-COMPETING CONTINUATION	$6,920,200
														Subtotal = $6,920,200

Issue Date FY: 2015 ( Subtotal = $6,421,209 )
2015	2015	DANA-FARBER CANCER INSTITUTE	44 BINNEY STREET	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	000	2	3/2/2015	NON-COMPETING CONTINUATION	$6,071,305
2015	2015	DANA-FARBER CANCER INSTITUTE	44 BINNEY STREET	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	001	2	9/2/2015	NON-COMPETING CONTINUATION	$349,904
														Subtotal = $6,421,209

Issue Date FY: 2014 ( Subtotal = $6,078,305 )
2014	2014	DANA-FARBER CANCER INSTITUTE	44 BINNEY STREET	BOSTON	MA	02115	SUFFOLK	USA	Cancer Treatment Research	000	1	4/29/2014	NEW	$6,078,305
														Subtotal = $6,078,305

Grand Total All Awards = $89,736,961

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ECOG-ACRIN Network Group Statistics and Data Management Center

Award Number: U10CA180794

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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