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NSABP COMMUNITY CLINICAL ONCOLOGY PROGRAM RESEARCH BASE - OPERATIONS CENTER

Award Number: U10CA037377
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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NSABP COMMUNITY CLINICAL ONCOLOGY PROGRAM RESEARCH BASE - OPERATIONS CENTER - DESCRIPTION (provided by applicant): The National Surgical Adjuvant Breast and Bowel Project (NSABP) is an NCI-funded clinical trials cooperative group for cancer treatment and prevention and control research. The group has a more than 40-year history of conducting large-scale controlled treatment trials that have improved the outcome for patients with breast or colorectal cancer and have provided a better understanding of tumor biology. In 1992, the NSABP extended its research agenda to include cancer prevention trials. The NSABP has been a CCOP Research Base since the inception of the CCOP Program and 45 CCOPs and 8 MBCCOPs currently list the NSABP among their research bases. CCOP participation in NSABP treatment and prevention trials is substantial; approximately 30% of NSABP accrual is attributable to CCOP investigators. This application requests continued funding for the NSABP to continue as a CCOP Research Base for the period of June 1, 2012, through May 31, 2017. During the proposed grant period, the NSABP will 1) continue to design and implement multi-institutional cancer treatment and prevention and control clinical trials; 2) analyze, report, and publish the results of current NSABP studies; 3) implement recruitment mechanisms and procedures to achieve adequate accrual and foster the participation of women and minorities in NSABP clinical trials; 4) maintain data collection, data monitoring, and quality control procedures that are in compliance with federal guidelines; 5) monitor CCOP performance through ongoing quality assurance programs; and, 6) continue the integration of CCOP investigators into the overall functioning of the NSABP. RELEVANCE (See instructions): Breast and bowel represents a major public health issue with a combined incidence of 361,530 cases in the United States in 2010 and more than 96,140 deaths attributed to the cancers. The NSABP has a 50+ year history of conducting high quality cancer, treatment, prevention, and control clinical trials that have substantially improved the survival and the quality of life of individuals with these diseases. This application will allow th NSABP to continue this important research that has the potential to impact the care of women and men in the United States and around the world.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2020 ( Subtotal = $0 )
2020	2014	NSABP FOUNDATION, INC.	TWO ALLEGHENY CTR STE 1200	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	000	28	10/1/2019	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $0

Issue Date FY: 2017 ( Subtotal = -$75,996 )
2017	2014	NSABP FOUNDATION, INC.	TWO ALLEGHENY CTR STE 1200	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	000	28	5/26/2017	SUPPLEMENT FOR EXPANSION	-$75,996
														Subtotal = -$75,996

Issue Date FY: 2016 ( Subtotal = $0 )
2016	2014	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	002	28	6/30/2016	SUPPLEMENT FOR EXPANSION	$0
2016	2013	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	000	28	6/30/2016	SUPPLEMENT FOR EXPANSION	$0
2016	2013	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	001	28	6/30/2016	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2015 ( Subtotal = $0 )
2015	2014	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	001	28	8/19/2015	SUPPLEMENT FOR EXPANSION	$0
2015	2013	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	002	28	8/19/2015	NON-COMPETING CONTINUATION	$0
2015	2013	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	000	28	8/19/2015	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $0

Issue Date FY: 2014 ( Subtotal = $100,000 )
2014	2014	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	000	28	5/29/2014	SUPPLEMENT FOR EXPANSION	$100,000
2014	2013	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	001	28	5/29/2014	NON-COMPETING CONTINUATION	$0
														Subtotal = $100,000

Issue Date FY: 2013 ( Subtotal = $8,917,710 )
2013	2013	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	003	28	9/5/2013	SUPPLEMENT FOR EXPANSION	$348,600
2013	2013	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	002	28	8/22/2013	SUPPLEMENT FOR EXPANSION	$6,339,793
2013	2013	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	001	28	8/21/2013	NON-COMPETING CONTINUATION	$1,582,384
2013	2013	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	000	27	7/12/2013	SUPPLEMENT FOR EXPANSION	$646,933
														Subtotal = $8,917,710

Issue Date FY: 2012 ( Subtotal = $3,659,425 )
2012	2012	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	000	27	8/23/2012	COMPETING CONTINUATION	$3,659,425
														Subtotal = $3,659,425

Issue Date FY: 2011 ( Subtotal = $6,937,584 )
2011	2011	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	000	26	8/15/2011	NON-COMPETING CONTINUATION	$6,937,584
														Subtotal = $6,937,584

Issue Date FY: 2010 ( Subtotal = $5,425,084 )
2010	2010	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	000	25	9/20/2010	NON-COMPETING CONTINUATION	$5,425,084
														Subtotal = $5,425,084

Issue Date FY: 2009 ( Subtotal = $6,177,145 )
2009	2009	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	002	24	9/21/2009	NON-COMPETING CONTINUATION	$0
2009	2009	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	004	24	9/18/2009	SUPPLEMENT FOR EXPANSION	$0
2009	2009	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	003	24	7/16/2009	SUPPLEMENT FOR EXPANSION	$123,992
2009	2009	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	001	24	6/17/2009	NON-COMPETING CONTINUATION	$6,053,153
2009	2008	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	000	23	11/3/2008	NON-COMPETING CONTINUATION	$0
														Subtotal = $6,177,145

Issue Date FY: 2008 ( Subtotal = $4,098,713 )
2008	2008	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	001	23	7/15/2008	SUPPLEMENT FOR EXPANSION	$1,657,976
2008	2008	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	000	23	7/14/2008	NON-COMPETING CONTINUATION	$1,275,285
2008	2008	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	002	23	8/29/2008	SUPPLEMENT FOR EXPANSION	$1,046,226
2008	2008	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Cause and Prevention Research	003	23	9/19/2008	SUPPLEMENT FOR EXPANSION	$119,226
														Subtotal = $4,098,713

Issue Date FY: 2007 ( Subtotal = $8,362,537 )
2007	2007	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	001	22	7/27/2007	SUPPLEMENT FOR EXPANSION	$4,237,409
2007	2007	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	000	22	7/27/2007	COMPETING CONTINUATION	$4,125,128
														Subtotal = $8,362,537

Issue Date FY: 2006 ( Subtotal = $5,548,610 )
2006	2006	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	002	21	6/12/2006	SUPPLEMENT FOR EXPANSION	$744,967
2006	2006	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Cause and Prevention Research	003	21	7/21/2006	SUPPLEMENT FOR EXPANSION	$80,000
2006	2006	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	004	21	9/15/2006	SUPPLEMENT FOR EXPANSION	$4,723,643
														Subtotal = $5,548,610

Issue Date FY: 2004 ( Subtotal = $11,093,612 )
2004	2004	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	001	20	7/30/2004	SUPPLEMENT FOR EXPANSION	$9,785,951
2004	2004	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	000	20	7/23/2004	NON-COMPETING CONTINUATION	$1,307,661
														Subtotal = $11,093,612

Issue Date FY: 2003 ( Subtotal = $8,203,990 )
2003	2003	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	000	19	6/9/2003	NON-COMPETING CONTINUATION	$815,136
2003	2003	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	001	19	6/17/2003	SUPPLEMENT FOR EXPANSION	$7,388,854
														Subtotal = $8,203,990

Grand Total All Awards = $116,878,819

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NSABP COMMUNITY CLINICAL ONCOLOGY PROGRAM RESEARCH BASE - OPERATIONS CENTER

Award Number: U10CA037377

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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