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NATIONAL SURGICAL ADJUVANT BREAST AND BOWEL PROJECT

Award Number: U10CA012027
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 12/01/1976
PERIOD OF PERFORMANCE END DATE: 01/31/2014

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NATIONAL SURGICAL ADJUVANT BREAST AND BOWEL PROJECT - The American Cancer Society estimated that in 2004, breast or colorectal cancer would strike over 350,000 Americans and close to 100,000 people would die from these diseases. The National Surgical Adjuvant Breast and Bowel Project(NSABP) is a multi-center clinical cooperative trials group with nearly 200 member institutions located throughout the US, Canada and Puerto Rico. The primary research objective of the NSABP is to conduct therapeutic research designed to improve the survival and the quality of life for persons with breast or colorectal cancer. This goal is achieved through the conduct of definitive phase III trials and the developmental efforts that lead to them. In calendar years 2002 and 2003, the NSABP entered 10,270 breast cancer patients and 962 colorectal cancer patients into adjuvant therapy trials. According to NCI data, this represents 64% of the breast cancer patients and 78% of the colorectal cancer patients entering NCI sponsored phase III cooperative group adjuvant breast or colorectal adjuvant trials. The NSABP integrates key behavior and health outcomes into its phase III trials to provide added value to the traditional endpoints of disease-free and overall survival. The NSABP also conducts correlative laboratory research in conjunction with its clinical trials designed to improve methods of assessing prognosis and predicting response to treatment with the aim of optimizing therapy for individual patients. In the proposed project period our aim will be to continue to improve breast and colorectal cancer therapies through the development and conduct of well-designed Phase III adjuvant therapy trials which will be carried out at our extensive network of affiliated members throughout North America.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2013 ( Subtotal = $0 )
2013	2011	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	000	41	2/5/2013	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2012 ( Subtotal = $3,834,085 )
2012	2012	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	000	41	4/6/2012	SUPPLEMENT FOR EXPANSION	$1,947,573
2012	2012	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	001	41	8/17/2012	SUPPLEMENT FOR EXPANSION	$1,886,512
														Subtotal = $3,834,085

Issue Date FY: 2011 ( Subtotal = $9,153,574 )
2011	2011	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	000	41	3/18/2011	NON-COMPETING CONTINUATION	$6,353,236
2011	2011	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	001	41	9/6/2011	SUPPLEMENT FOR EXPANSION	$2,800,338
														Subtotal = $9,153,574

Issue Date FY: 2010 ( Subtotal = $8,633,329 )
2010	2010	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Trans-NIH Recovery Act Research Support	001	40	7/2/2010	SUPPLEMENT FOR EXPANSION	$188,932
2010	2010	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	002	40	7/8/2010	NON-COMPETING CONTINUATION	$414,748
2010	2010	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	000	40	4/23/2010	NON-COMPETING CONTINUATION	$8,029,649
														Subtotal = $8,633,329

Issue Date FY: 2009 ( Subtotal = $6,161,066 )
2009	2009	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	001	39	4/20/2009	NON-COMPETING CONTINUATION	$1,091,133
2009	2009	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Trans-NIH Recovery Act Research Support	003	39	9/17/2009	SUPPLEMENT FOR EXPANSION	$69,847
2009	2009	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	000	39	2/2/2009	NON-COMPETING CONTINUATION	$5,000,086
2009	2009	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	002	39	9/14/2009	NON-COMPETING CONTINUATION	$0
														Subtotal = $6,161,066

Issue Date FY: 2008 ( Subtotal = $7,352,911 )
2008	2008	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	000	38	2/19/2008	NON-COMPETING CONTINUATION	$7,116,748
2008	2008	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	001	38	9/4/2008	SUPPLEMENT FOR EXPANSION	$236,163
														Subtotal = $7,352,911

Issue Date FY: 2007 ( Subtotal = $8,853,989 )
2007	2007	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	000	37	2/22/2007	NON-COMPETING CONTINUATION	$8,403,989
2007	2007	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	001	37	8/20/2007	SUPPLEMENT FOR EXPANSION	$450,000
														Subtotal = $8,853,989

Issue Date FY: 2006 ( Subtotal = $10,101,414 )
2006	2006	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	000	36	4/21/2006	COMPETING CONTINUATION	$10,101,414
														Subtotal = $10,101,414

Issue Date FY: 2004 ( Subtotal = $10,127,948 )
2004	2004	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	000	34	2/10/2004	NON-COMPETING CONTINUATION	$10,127,948
														Subtotal = $10,127,948

Issue Date FY: 2003 ( Subtotal = $10,967,068 )
2003	2003	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	000	33		NON-COMPETING CONTINUATION	$10,511,979
2003	2003	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	002	33	8/27/2003	SUPPLEMENT FOR EXPANSION	$386,095
2003	2003	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	001	33		SUPPLEMENT FOR EXPANSION	$68,994
														Subtotal = $10,967,068

Issue Date FY: 2002 ( Subtotal = $12,438,784 )
2002	2002	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	001	32	9/27/2002	SUPPLEMENT FOR EXPANSION	$86,328
2002	2002	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	000	32	9/30/2002	NON-COMPETING CONTINUATION	$12,352,456
														Subtotal = $12,438,784

Issue Date FY: 2001 ( Subtotal = $10,728,360 )
2001	2001	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	000	31	9/12/2001	NON-COMPETING CONTINUATION	$10,528,360
2001	2001	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	001	31	9/5/2001	SUPPLEMENT FOR EXPANSION	$200,000
														Subtotal = $10,728,360

Issue Date FY: 2000 ( Subtotal = $8,076,116 )
2000	2000	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	000	30	9/22/2000	COMPETING CONTINUATION	$8,076,116
														Subtotal = $8,076,116

Issue Date FY: 1999 ( Subtotal = $4,871,409 )
1999	1999	NSABP FOUNDATION, INC	4 ALLEGHENY CENTER 5TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	000	29	9/1/1999	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$4,871,409
														Subtotal = $4,871,409

Issue Date FY: 1998 ( Subtotal = $1,598,908 )
1998	1998	ALLEGHENY SINGER RESEARCH CORP	320 East North Avenue	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Control	001	28	9/14/1998	SUPPLEMENT FOR EXPANSION	$229,639
1998	1998	ALLEGHENY SINGER RESEARCH CORP	320 East North Avenue	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Treatment Research	000	28	1/29/1998	NON-COMPETING CONTINUATION	$1,369,269
														Subtotal = $1,598,908

Grand Total All Awards = $112,898,961

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NATIONAL SURGICAL ADJUVANT BREAST AND BOWEL PROJECT

Award Number: U10CA012027

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 12/01/1976

PERIOD OF PERFORMANCE END DATE: 01/31/2014

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