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Global Environmental and Occupational Health Research and Training for Eastern Africa

Award Number: U01TW010094
ORGANIZATION: FOGARTY INTERNATIONAL CENTER
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/28/2015
PERIOD OF PERFORMANCE END DATE: 02/28/2027

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Global Environmental and Occupational Health Research and Training for Eastern Africa - PROJECT SUMMARY/ABSTRACT This application requests renewal of an interdisciplinary mentored research program that will be supported by the linked U2R application (2/2: GEOHealth Hub for Research and Training in Eastern Africa – Ethiopia). Building on successes and lessons from the current program, the linked training and research programs of the Hub will advance research and the translation of locally-relevant findings into action around pressing public health issues related to air pollution exposure and health effects, and occupational exposure to extreme heat. The research and training program will be implemented in collaboration with Addis Ababa University (AAU) in Ethiopia, the Hub institution for the linked application. Spoke institutions are in Kenya (University of Nairobi) and Uganda (Makerere University). The research approach is structured around five aims. In Aim 1, the Hub will continue three activities that were successfully established during the first funding cycle, but that would be significantly enhanced by longitudinal data collection. Specifically, we propose to continue central site monitoring of air quality (fine particulate matter, or PM2.5) using infrastructure established in Cycle 1 in each city; to continue collecting hospital mortality and morbidity records in each city to enable time series studies linking air pollution and health; and to re-evaluate the respiratory health of the children included in the first cycle (the Eastern Africa Children’s Health Study – EACH) to examine the effect of PM2.5 on lung development trajectories. In Aim 2 we will measure personal air pollution exposure in 300 mother-child dyads in each city, supporting modeling of personal exposure in our entire child cohort and to establish a foundation for modeling personal exposure in our entire child cohort and for additional epidemiological studies of air pollution. Aim 3 will carry out a cross-sectional assessment of mothers of a subset of children in the EACH study to examine the effects of air pollution exposure on the respiratory and reproductive health of the woman/child dyad. In Aim 4, we seek to build on the enhanced capabilities and independence of the Hub investigators developed in Cycle 1 to conduct studies designed by each country based on local interest and relevance. In Ethiopia, we will implement a full version of a Cycle 1 pilot study of renal function and chronic kidney disease risk resulting from occupational heat stress. In Uganda we will assess ambulatory blood pressure in the subsample of EACH study children with personal exposure data. In Kenya, we will assess neurocognitive function in EACH study children using both test scores (full cohort) and psychometrics (personal exposure subsample). Aim 5 is to continue impacting policy and regulatory decisions via dissemination of study findings to central stakeholders at the local, national and regional level. This proposal brings together a transdisciplinary team of experts in environmental monitoring, epidemiology, and environmental policy; builds on the partners’ well-established research collaborations; and, promises to generate the evidence needed to support healthier environments and workplaces throughout Eastern Africa and beyond.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $298,123 )
2025	2025	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	000	9	3/18/2025	NON-COMPETING CONTINUATION	$298,123
														Subtotal = $298,123

Issue Date FY: 2024 ( Subtotal = $382,591 )
2024	2024	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	001	8	8/30/2024	SUPPLEMENT FOR EXPANSION	$84,468
2024	2024	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	000	8	4/16/2024	NON-COMPETING CONTINUATION	$298,123
														Subtotal = $382,591

Issue Date FY: 2023 ( Subtotal = $298,123 )
2023	2023	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	000	7	3/7/2023	NON-COMPETING CONTINUATION	$298,123
2023	2019	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	001	5	5/9/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $298,123

Issue Date FY: 2022 ( Subtotal = $298,123 )
2022	2022	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	005	6	6/20/2022	COMPETING CONTINUATION	$0
2022	2022	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	004	6	6/3/2022	COMPETING CONTINUATION	$298,123
2022	2022	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	007	6	9/15/2022	COMPETING CONTINUATION	$0
2022	2022	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	006	6	7/10/2022	COMPETING CONTINUATION	$0
2022	2020	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	002	5	5/30/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2020	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	003	5	5/30/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2019	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	001	5	5/30/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2019	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	000	5	5/30/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $298,123

Issue Date FY: 2021 ( Subtotal = $0 )
2021	2020	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	003	5	7/27/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2020	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	002	5	7/27/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2019	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	001	5	7/27/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2019	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	000	5	7/27/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2020 ( Subtotal = $222,783 )
2020	2020	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	001	5	8/29/2020	SUPPLEMENT FOR EXPANSION	$199,995
2020	2020	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	002	5	9/4/2020	SUPPLEMENT FOR EXPANSION	$22,788
2020	2019	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	000	5	8/14/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $222,783

Issue Date FY: 2019 ( Subtotal = $183,489 )
2019	2019	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	003	5	9/24/2019	SUPPLEMENT FOR EXPANSION	$17,388
2019	2019	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	002	5	9/20/2019	NON-COMPETING CONTINUATION	$166,101
2019	2018	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	001	4	2/13/2019	NON-COMPETING CONTINUATION	$0
2019	2018	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	000	4	12/11/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $183,489

Issue Date FY: 2018 ( Subtotal = $175,934 )
2018	2018	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	000	4	8/16/2018	NON-COMPETING CONTINUATION	$175,934
														Subtotal = $175,934

Issue Date FY: 2017 ( Subtotal = $184,679 )
2017	2017	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	000	3	8/26/2017	NON-COMPETING CONTINUATION	$184,679
2017	2017	ADDIS ABABA UNIVERSITY	ENTOTO ROAD	ADDIS ABABA				ETH	International Research and Research Training	001	3	9/21/2017	NON-COMPETING CONTINUATION	$0
														Subtotal = $184,679

Issue Date FY: 2016 ( Subtotal = $143,854 )
2016	2016	ADDIS ABABA UNIVERSITY	Mekude Bentyirgu Street	ADDIS ABABA				ETH	International Research and Research Training	000	2	8/26/2016	NON-COMPETING CONTINUATION	$143,854
														Subtotal = $143,854

Issue Date FY: 2015 ( Subtotal = $103,475 )
2015	2015	ADDIS ABABA UNIVERSITY	Mekude Bentyirgu Street	ADDIS ABABA				ETH	International Research and Research Training	000	1	9/24/2015	NEW	$103,475
														Subtotal = $103,475

Grand Total All Awards = $2,291,174

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Global Environmental and Occupational Health Research and Training for Eastern Africa

Award Number: U01TW010094

ORGANIZATION: FOGARTY INTERNATIONAL CENTER

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/28/2015

PERIOD OF PERFORMANCE END DATE: 02/28/2027

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