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Enhanced Surveillance for Newly Preventable Diseases (ARI and AGE Surveillance) - Rochester, NY

Award Number: U01IP001049
ORGANIZATION: NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES(NCIRD)
OPDIV: CDC
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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ABSTRACT This proposal is to enhance the New Vaccine Surveillance Network (NVSN) site in Rochester, NY, which has for 10 years been focused on prospective, population-based surveillance for acute gastroenteritis (AGE) caused by rotavirus, norovirus, and other viral pathogens, and for the past year, population-based surveillance for acute respiratory infections. We propose to continue and extend surveillance for ARI with a focus on influenza, respiratory syncytial virus (RSV), enterovirus-D68 (EV-D68), and other vaccine- preventable or potentially vaccine-preventable viruses, in order to both measure influenza vaccine effectiveness (VE) in preventing laboratory-confirmed influenza infections among hospitalized children <18 years of age, and to assess the inpatient burden of viral pathogens associated with ARIs, particularly influenza, RSV and EV-D68. We also will continue the AGE surveillance to allow for similar determinations of AGE burden and rotavirus vaccine efficacy among children hospitalized or visiting the emergency departments. The over-arching goal of the NVSN is to inform the nation about the burden of vaccine-preventable diseases (VPDs), and the impact of new vaccines and vaccine policies. Our Rochester NVSN site (a founding NVSN member), has been a leader in shaping all aspects of the NVSN, including population-based surveillance for new or upcoming vaccines, vaccine effectiveness (VE) studies, refinement of diagnostic laboratory methods, health services and epidemiologic studies, and dissemination of findings. We have the infrastructure and comprehensive expertise to begin all activities on day 1 of the funding period. Our NVSN site has: experienced personnel who have led and published many past NVSN influenza VE, surveillance, and molecular diagnostic laboratory studies; accurate laboratory and surveillance techniques consistent with CDC procedures; and outstanding epidemiologic and health services research capabilities. We have full access to all hospital and ED databases to complement surveillance activities. Our catchment area, the Monroe County NY/Rochester Metropolitan Statistical Area, has a total population of >1,000,000; >95% of ARI admissions for Monroe County resident children <18 years of age occur at our two NVSN hospitals, with nearly 1,000 hospitalizations for ARIs per year. Thus, we have a “captured population” precisely suited for the NVSN population-based surveillance projects. This proposal will provide critical information to develop sound polices consistent with national goals to preventing VPD in children.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2022 ( Subtotal = -$810,226 )
2022	2020	University of Rochester	500 Joseph C Wilson Blvd	Rochester	NY	14627	MONROE	USA	Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects	04	5	7/25/2022	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	-$810,226
2022	2019	University of Rochester	500 Joseph C Wilson Blvd	Rochester	NY	14627	MONROE	USA	Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects	04	5	7/25/2022	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2022	2018	University of Rochester	500 Joseph C Wilson Blvd	Rochester	NY	14627	MONROE	USA	Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects	04	5	7/25/2022	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2022	2017	University of Rochester	500 Joseph C Wilson Blvd	Rochester	NY	14627	MONROE	USA	Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects	04	5	7/25/2022	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2022	2016	University of Rochester	500 Joseph C Wilson Blvd	Rochester	NY	14627	MONROE	USA	Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects	04	5	7/25/2022	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
														Subtotal = -$810,226

Issue Date FY: 2021 ( Subtotal = -$2,718 )
2021	2020	University of Rochester	500 Joseph C Wilson Blvd	Rochester	NY	14627	MONROE	USA	Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects	02	5	9/1/2021	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2021	2020	University Of Rochester	500 Joseph C Wilson Blvd	Rochester	NY	14627	MONROE	USA	Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects	01	5	8/23/2021	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2021	2016	University Of Rochester	500 Joseph C Wilson Blvd	Rochester	NY	14627	MONROE	USA	Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects	03	5	6/16/2021	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	-$2,718
														Subtotal = -$2,718

Issue Date FY: 2020 ( Subtotal = $1,805,484 )
2020	2020	University of Rochester	500 Joseph C Wilson Blvd	Rochester	NY	14627	MONROE	USA	Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects	00	5	7/10/2020	NON-COMPETING CONTINUATION	$1,505,484
2020	2020	University of Rochester	500 Joseph C Wilson Blvd	Rochester	NY	14627	MONROE	USA	Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects	03	4	5/29/2020	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$300,000
2020	2019	University Of Rochester	500 Joseph C Wilson Blvd	Rochester	NY	14627	MONROE	USA	Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects	02	4	12/20/2019	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2020	2019	University of Rochester	500 Joseph C Wilson Blvd	Rochester	NY	14627	MONROE	USA	Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects	03	4	5/29/2020	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
														Subtotal = $1,805,484

Issue Date FY: 2019 ( Subtotal = $1,250,000 )
2019	2019	University of Rochester	500 Joseph C Wilson Blvd	Rochester	NY	14627	MONROE	USA	Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects	01	4	8/1/2019	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$250,000
2019	2019	University of Rochester	500 Joseph C Wilson Blvd	Rochester	NY	14627	MONROE	USA	Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects	00	4	6/24/2019	NON-COMPETING CONTINUATION	$1,000,000
														Subtotal = $1,250,000

Issue Date FY: 2018 ( Subtotal = $1,226,950 )
2018	2018	University Of Rochester	500 Joseph C Wilson Blvd	Rochester	NY	14627	MONROE	USA	Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects	00	3	8/9/2018	NON-COMPETING CONTINUATION	$1,226,950
2018	2016	University Of Rochester	500 Joseph C Wilson Blvd	Rochester	NY	14627	MONROE	USA	Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects	01	2	2/28/2018	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
														Subtotal = $1,226,950

Issue Date FY: 2017 ( Subtotal = $1,000,000 )
2017	2017	UNIVERSITY OF ROCHESTER	500 JOSEPH C WILSON BLVD	ROCHESTER	NY	14627	MONROE	USA	Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects	001	2	8/7/2017	NON-COMPETING CONTINUATION	$1,000,000
2017	2016	UNIVERSITY OF ROCHESTER	601 ELMWOOD AVE	ROCHESTER	NY	14642	MONROE	USA	Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects	000	1	10/18/2016	NEW	$0
														Subtotal = $1,000,000

Issue Date FY: 2016 ( Subtotal = $1,000,000 )
2016	2016	UNIVERSITY OF ROCHESTER	1325 MOUNT HOPE AVE, SUITE 260	ROCHESTER	NY	14642	MONROE	USA	Prevention and Public Health Fund (Affordable Care Act): Enhanced Surveillance for New Vaccine Preventable Disease	001	1	8/16/2016	SUPPLEMENT FOR EXPANSION	$785,715
2016	2016	UNIVERSITY OF ROCHESTER	1325 MOUNT HOPE AVE, SUITE 260	ROCHESTER	NY	14642	MONROE	USA	Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects	000	1	8/15/2016	NEW	$214,285
														Subtotal = $1,000,000

Grand Total All Awards = $5,469,490

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Enhanced Surveillance for Newly Preventable Diseases (ARI and AGE Surveillance) - Rochester, NY

Award Number: U01IP001049

ORGANIZATION: NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES(NCIRD)

OPDIV: CDC

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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