Wednesday, April 2, 2025 4/2/2025

Surviving the HIV Epidemic (S/HE) in metropolitan Washington DC - Advancing knowledge through cohort studies

Award Number: U01HL146205
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Group Awards By:

View Award Description

Surviving the HIV Epidemic (S/HE) in metropolitan Washington DC - Advancing knowledge through cohort studies - ABSTRACT About 1.1 million people are living with HIV (PLWH) in the US, with an estimated 39,782 individuals newly diagnosed with HIV in 2016. The Multicenter AIDS Cohort Study (MACS) and the Women’s Interagency HIV Study (WIHS) are two of the longest standing HIV cohort studies in the United States. Established in 1984 and 1993, respectively, these US-based cohorts currently follow 2,235 men and 2,304 women living with HIV, alongside high-risk but uninfected controls. HIV is at epidemic proportions in the nation’s capital, with overall HIV prevalence of 1.9% among the District of Columbia (DC) adult and adolescent residents. Approximately 3.7% of DC residents aged 40 to 49 years and 5.2% of residents aged 50 to 59 years are living with HIV. The highest life time risk of acquiring HIV in the U.S. is highest in DC with an estimated 1 in 17 individuals anticipated to acquire HIV in their lifetime, followed by 1 in 56 risk among the neighboring Maryland residents. Continuing to follow the women we have recruited and expanding our cohort to include a representative group of men and women is imperative in this region with epidemic levels of HIV. Our research will be focused on understanding the behavioral and social determinants that contribute to long term treatment success and failure, with a focus on identifying key resilience factors that may translate into innovative interventions to achieve the global goals of the HIV care continuum, to improve treatment uptake and viral suppression to decrease morbidity and mortality. We have four aims to achieve our goals. (1) To continue our strong collaborative relationship with the national MACS/WIHS CCS in protocol development, implementation, participant enrollment, retention, data acquisition, and sub-study participation; (2) To lead the CCS-wide effort to understand the psychosocial and behavioral determinants that contributes to treatment adherence, virologic suppression, and healthy coping among PLWH in the US; (3) To determine the effectiveness of treatment and prevention guidelines and identify disparities in service delivery for common morbidities with high associated mortality; and (4) To explore HIV, aging, and associated co-morbidities, including the role of microvascular/vascular function, the microbiome, neurocognitive decline in the context of contemporary antiretroviral treatment regimens, and hearing and balance disorders among men and women. Our long-term goal is to improve the health of people living with HIV and to help prevent those without HIV from seroconverting.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $2,589,325 )
2025	2025	GEORGETOWN UNIVERSITY	MAIN CAMPUS	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	001	7	3/27/2025	NON-COMPETING CONTINUATION	$2,589,325
2025	2024	GEORGETOWN UNIVERSITY	MAIN CAMPUS	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	000	6	2/28/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,589,325

Issue Date FY: 2024 ( Subtotal = $2,852,127 )
2024	2024	GEORGETOWN UNIVERSITY	MAIN CAMPUS	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	001	6	5/20/2024	NON-COMPETING CONTINUATION	$2,852,127
2024	2023	GEORGETOWN UNIVERSITY	MAIN CAMPUS	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	000	5	2/16/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,852,127

Issue Date FY: 2023 ( Subtotal = $2,839,771 )
2023	2023	GEORGETOWN UNIVERSITY	MAIN CAMPUS	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	000	5	4/28/2023	NON-COMPETING CONTINUATION	$2,839,771
														Subtotal = $2,839,771

Issue Date FY: 2022 ( Subtotal = $2,905,179 )
2022	2022	GEORGETOWN UNIVERSITY (THE)	37TH AND O ST NW	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	000	4	4/22/2022	NON-COMPETING CONTINUATION	$2,905,179
														Subtotal = $2,905,179

Issue Date FY: 2021 ( Subtotal = $2,939,532 )
2021	2021	GEORGETOWN UNIVERSITY (THE)	37TH AND O ST NW	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	002	3	8/16/2021	SUPPLEMENT FOR EXPANSION	$35,088
2021	2021	GEORGETOWN UNIVERSITY (THE)	37TH AND O ST NW	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	001	3	3/11/2021	NON-COMPETING CONTINUATION	$2,904,444
2021	2020	GEORGETOWN UNIVERSITY (THE)	37TH AND O ST NW	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	000	2	11/24/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,939,532

Issue Date FY: 2020 ( Subtotal = $3,015,201 )
2020	2020	GEORGETOWN UNIVERSITY (THE)	37TH AND O ST NW	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	006	2	8/25/2020	SUPPLEMENT FOR EXPANSION	$4,251
2020	2020	GEORGETOWN UNIVERSITY (THE)	37TH AND O ST NW	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	004	2	6/17/2020	SUPPLEMENT FOR EXPANSION	$18,015
2020	2020	GEORGETOWN UNIVERSITY (THE)	37TH AND O ST NW	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	002	2	4/14/2020	NON-COMPETING CONTINUATION	$0
2020	2020	GEORGETOWN UNIVERSITY (THE)	37TH AND O ST NW	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	001	2	3/30/2020	NON-COMPETING CONTINUATION	$2,881,859
2020	2020	GEORGETOWN UNIVERSITY (THE)	37TH AND O ST NW	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	007	2	9/10/2020	SUPPLEMENT FOR EXPANSION	$54,481
2020	2020	GEORGETOWN UNIVERSITY (THE)	37TH AND O ST NW	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	005	2	8/15/2020	SUPPLEMENT FOR EXPANSION	$56,595
2020	2020	GEORGETOWN UNIVERSITY (THE)	37TH AND O ST NW	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	003	2	5/29/2020	NON-COMPETING CONTINUATION	$0
2020	2019	GEORGETOWN UNIVERSITY (THE)	37TH AND O ST NW	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	000	1	3/16/2020	NEW	$0
														Subtotal = $3,015,201

Issue Date FY: 2019 ( Subtotal = $3,208,369 )
2019	2019	GEORGETOWN UNIVERSITY (THE)	37TH & O ST NW	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	000	1	3/29/2019	NEW	$2,429,051
2019	2019	GEORGETOWN UNIVERSITY (THE)	37TH & O ST NW	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	003	1	9/12/2019	SUPPLEMENT FOR EXPANSION	$500,351
2019	2019	GEORGETOWN UNIVERSITY (THE)	37TH & O ST NW	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	002	1	6/7/2019	NEW	$5,949
2019	2019	GEORGETOWN UNIVERSITY (THE)	37TH & O ST NW	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	004	1	9/16/2019	SUPPLEMENT FOR EXPANSION	$23,019
2019	2019	GEORGETOWN UNIVERSITY (THE)	37TH & O ST NW	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	005	1	9/18/2019	SUPPLEMENT FOR EXPANSION	$249,999
2019	2019	GEORGETOWN UNIVERSITY (THE)	37TH & O ST NW	WASHINGTON	DC	20057	DISTRICT OF COLUMBIA	USA	Cardiovascular Diseases Research	001	1	4/18/2019	NEW	$0
														Subtotal = $3,208,369

Grand Total All Awards = $20,349,504

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Surviving the HIV Epidemic (S/HE) in metropolitan Washington DC - Advancing knowledge through cohort studies

Award Number: U01HL146205

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer