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Detection and surveillance of antimicrobial resistance among enteric bacteria from raw retail meat and seafood in Iowa: A NARMS Retail Food Surveillance Project

Award Number: U01FD007136
ORGANIZATION: FOOD AND DRUG ADMINISTRATION
OPDIV: FDA
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Project Summary/Abstract Detection and surveillance of antimicrobial resistance among enteric bacteria from raw retail meat and seafood in Iowa: A NARMS Retail Food Surveillance Project Antimicrobial resistance (AMR) is a major health threat affecting the well-being of humans, animals, and the environment worldwide. Robust and comprehensive surveillance systems emphasizing the “One Health” approach are necessary for effectively combatting AMR. In the United States, the retail arm of the National Antimicrobial Resistance Monitoring System (NARMS) under the Food and Drug Administration, Center for Veterinary Medicine (FDA- CVM) performs surveillance of AMR in select enteric bacteria (non-typhoidal Salmonella, Campylobacter, Enterococcus and Escherichia coli) from retail raw meats (chicken, ground turkey and beef, and ground/chop pork) in 18 states. Recently, surveillance of AMR in retail seafood (tilapia, shrimp, salmon) for select bacteria (Vibrio, Aeromonas, E. coli, Enterococcus, carbapenemase-producing Enterobacteriaciae) has also been started in at least 8 states. The NARMS program has contributed significantly to monitoring the sources and trends of AMR in the food chain. To enhance the effort on combating AMR, FDA launched a cooperative agreement program to expand the NARMS surveillance network throughout the U.S in 2016. Under the initiative, Iowa State University (ISU) became a NARMS network laboratory in late 2016. Since then, the ISU site has contributed substantially to strengthening the capacity and effectiveness of the national AMR surveillance program in retail food. In this application, we propose to continue the collaborative partnership with NARMS to address the updated goals of the Retail Food Surveillance Program as described in FOA PAR-20-124 “NARMS Cooperative Agreement Program to Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens”. Specifically, we will continue to collect and process raw meat samples and seafood samples from grocery stores in Iowa and culture them for isolation of bacteria of interest as defined by NARMS, and ship the isolates to FDA on a monthly basis. In addition, we will continue to perform whole-genome sequencing of Salmonella, Campylobacter and E. coli isolates from the meat samples and share the sequences with FDA via GenomeTrakr. This application is built on existing experience and is a natural extension of our current effort with NARMS. Trained personnel and logistic infrastructure required for successful completion of the planned work are already in place. We strongly believe that ISU’s continued participation in this collaborative network will contribute significantly to mitigation of AMR in the food chain and ultimately to enhancement of food safety and public health.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2024	IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY	1350 BEARDSHEAR HALL	AMES	IA	50011	STORY	USA	Antimicrobial Resistance Surveillance in Retail Food Specimens	000	5	11/19/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $190,000 )
2024	2024	IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY	1350 BEARDSHEAR HALL	AMES	IA	50011	STORY	USA	Antimicrobial Resistance Surveillance in Retail Food Specimens	000	5	8/30/2024	NON-COMPETING CONTINUATION	$190,000
														Subtotal = $190,000

Issue Date FY: 2023 ( Subtotal = $190,000 )
2023	2023	IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY	515 MORRILL RD, 1350 BEARDSHEAR HALL	AMES	IA	50011	STORY	USA	Antimicrobial Resistance Surveillance in Retail Food Specimens	000	4	8/7/2023	NON-COMPETING CONTINUATION	$190,000
2023	2023	IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY	1350 BEARDSHEAR HALL	AMES	IA	50011	STORY	USA	Antimicrobial Resistance Surveillance in Retail Food Specimens	001	4	9/20/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $190,000

Issue Date FY: 2022 ( Subtotal = $180,000 )
2022	2022	IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY	515 MORRILL RD, 1350 BEARDSHEAR HALL	AMES	IA	50011	STORY	USA	Antimicrobial Resistance Surveillance in Retail Food Specimens	000	3	9/1/2022	NON-COMPETING CONTINUATION	$180,000
														Subtotal = $180,000

Issue Date FY: 2021 ( Subtotal = $167,000 )
2021	2021	IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY	515 MORRILL RD, 1350 BEARDSHEAR HALL	AMES	IA	50011	STORY	USA	Antimicrobial Resistance Surveillance in Retail Food Specimens	000	2	8/30/2021	NON-COMPETING CONTINUATION	$167,000
														Subtotal = $167,000

Issue Date FY: 2020 ( Subtotal = $155,000 )
2020	2020	IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY	515 MORRILL RD, 1350 BEARDSHEAR HALL	AMES	IA	50011	STORY	USA	Antimicrobial Resistance Surveillance in Retail Food Specimens	001	1	9/17/2020	NEW	$0
2020	2020	IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY	515 MORRILL RD, 1350 BEARDSHEAR HALL	AMES	IA	50011	STORY	USA	Antimicrobial Resistance Surveillance in Retail Food Specimens	000	1	8/26/2020	NEW	$155,000
														Subtotal = $155,000

Grand Total All Awards = $882,000

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Detection and surveillance of antimicrobial resistance among enteric bacteria from raw retail meat and seafood in Iowa: A NARMS Retail Food Surveillance Project

Award Number: U01FD007136

ORGANIZATION: FOOD AND DRUG ADMINISTRATION

OPDIV: FDA

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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